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https://www.readbyqxmd.com/read/29785077/mediterranean-diet-and-nonalcoholic-fatty-liver-disease
#1
REVIEW
Caterina Anania, Francesco Massimo Perla, Francesca Olivero, Lucia Pacifico, Claudio Chiesa
Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstone of NAFLD management...
May 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29781841/carbohydrates-and-diet-patterns-in-nonalcoholic-fatty-liver-disease-in-children-and-adolescents
#2
Ahlia Sekkarie, Jean A Welsh, Miriam B Vos
PURPOSE OF REVIEW: The primary treatment for nonalcoholic fatty liver disease (NAFLD) in children is lifestyle change, including a healthier diet. However, there are no agreed upon expert recommendations for a specific diet in the prevention or treatment of NAFLD. In this study, we review studies published between 2015 and 2017 contributing to further understanding of the role of diet in the development and progression of NAFLD, particularly those addressing sugars and dietary patterns...
May 16, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29778381/dietary-patterns-are-positively-associated-with-semen-quality
#3
Michal Efrat, Anat Stein, Haim Pinkas, Ron Unger, Ruth Birk
OBJECTIVE: To study association of semen quality with a priori whole dietary pattern indexes, which reflect real-world dietary practices and the numerous combinations by which foods are consumed: Healthy Eating Index (HEI), Dietary Approaches to Stop Hypertension (DASH), alternate Mediterranean Diet score (aMED), and Alternative Healthy Eating Index (AHEI). DESIGN: A cross-sectional single-center study. SETTING: Hospital fertility center and university...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29775747/mediterranean-diet-and-depression-among-older-individuals-the-multinational-medis-study
#4
Maria F Masana, Josep Maria Haro, Anargiros Mariolis, Suzanne Piscopo, Giuseppe Valacchi, Vassiliki Bountziouka, Foteini Anastasiou, Akis Zeimbekis, Dimitra Tyrovola, Efthimios Gotsis, George Metallinos, Anna Polystipioti, Josep-Antoni Tur, Antonia-Leda Matalas, Christos Lionis, Evangelos Polychronopoulos, Labros S Sidossis, Stefanos Tyrovolas, Demosthenes B Panagiotakos
BACKGROUND: Depression has been linked to a large and growing economic and societal burden worldwide. In Europe, depression is one of the most frequent mental disorders across all age groups, but particularly in people aged 65 years and over, and higher depressive symptoms have been reported among individuals with chronic diseases (e.g., diabetes and heart disease). AIM: To evaluate the role of adherence to the Mediterranean diet (MedDiet) in depression in a sample of older people living in the Mediterranean basin...
May 15, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29769748/comparative-ecologic-relationships-of-saturated-fat-sucrose-food-groups-and-a-mediterranean-food-pattern-score-to-50-year-coronary-heart-disease-mortality-rates-among-16-cohorts-of-the-seven-countries-study
#5
Daan Kromhout, Alessandro Menotti, Adalberta Alberti-Fidanza, Paolo Emilio Puddu, Peter Hollman, Anthony Kafatos, Hanna Tolonen, Hisashi Adachi, David R Jacobs
BACKGROUND/OBJECTIVES: We studied the ecologic relationships of food groups, macronutrients, eating patterns, and an a priori food pattern score (Mediterranean Adequacy Index: MAI) with long-term CHD mortality rates in the Seven Countries Study. SUBJECTS/METHODS: Sixteen cohorts (12,763 men aged 40-59 years) were enrolled in the 1960s in seven countries (US, Finland, The Netherlands, Italy, Greece, former Yugoslavia: Croatia/Serbia, Japan). Dietary surveys were carried out at baseline and only in a subsample of each cohort...
May 17, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29767701/microbiome-mediated-effects-of-the-mediterranean-diet-on-inflammation
#6
Melisa A Bailey, Hannah D Holscher
The Mediterranean diet pattern is increasingly associated with improved metabolic health. Two mechanisms by which consuming a Mediterranean diet pattern may contribute to improved metabolic health are modulation of the gastrointestinal (GI) microbiota and reduction of metabolic endotoxemia. Metabolic endotoxemia, defined as a 2- to 3-fold increase in circulating levels of bacterial endotoxin, has been proposed as a cause of inflammation during metabolic dysfunction. As the largest source of endotoxins in the human body, the GI microbiota represents a crucial area for research on strategies for reducing endotoxemia...
May 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29766837/diet-quality-and-depressive-symptoms-in-adolescence-no-cross-sectional-or-prospective-associations-following-adjustment-for-covariates
#7
Eleanor M Winpenny, Anne-Laura van Harmelen, Martin White, Esther Mf van Sluijs, Ian M Goodyer
OBJECTIVE: Adolescence is a critical period for development of depression and understanding of behavioural risk factors is needed to support appropriate preventive strategies. We examined associations between adolescent diet quality and depressive symptoms, cross-sectionally and prospectively, in a large community cohort, adjusting for behavioural and psychosocial covariates. DESIGN: Prospective community-based cohort study (ROOTS). SETTING: Secondary schools in Cambridgeshire and Suffolk, UK...
May 16, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29765333/beneficial-effects-of-elderly-tailored-mediterranean-diet-on-the-proteasomal-proteolysis
#8
Sophia Athanasopoulou, Niki Chondrogianni, Aurelia Santoro, Konstantina Asimaki, Vasiliki Delitsikou, Konstantinos Voutetakis, Cristina Fabbri, Barbara Pietruszka, Joanna Kaluza, Claudio Franceschi, Efstathios S Gonos
Aging is a multifactorial process characterized by the accumulation of proteins undergoing oxidative modifications, either due to enhanced levels of oxidative stress or due to their decreased clearance; both facts are related to the establishment of chronic inflammatory processes. These processes are directly associated with functional and structural modifications of a key cellular component, namely the proteasome. In this study, levels of oxidized proteins, along with proteasome and immunoproteasome composition and activity on a selected group of 120 elderly volunteers were analyzed before and after the administration of a specific dietary protocol, based on an elderly tailored Mediterranean diet (the "NU-AGE diet")...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29763722/lifestyle-determinants-of-healthy-ageing-in-a-mediterranean-population-the-multinational-medis-study
#9
Alexandra Foscolou, Emmanuella Magriplis, Stefanos Tyrovolas, George Soulis, Vassiliki Bountziouka, Anargiros Mariolis, Suzanne Piscopo, Giuseppe Valacchi, Foteini Anastasiou, Efthimios Gotsis, George Metallinos, Dimitra Tyrovola, Anna Polystipioti, Evangelos Polychronopoulos, Antonia-Leda Matalas, Christos Lionis, Akis Zeimbekis, Josep-Antoni Tur, Labros S Sidossis, Demosthenes Panagiotakos
BACKGROUND: To evaluate modifiable, lifestyle risk factors of cardiovascular disease (CVD) among older adults, across ageing, in the Mediterranean area. METHODS: During 2005-2017, 3131 individuals from 26 Mediterranean islands of 5 countries, ≥65 years of age, were voluntarily enrolled. Anthropometrical, clinical and socio-demographic characteristics, dietary habits, lifestyle parameters were measured through standard procedures. Analyses were performed by year and across consecutive age groups of the participants...
May 12, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29757402/adherence-to-healthful-dietary-patterns-is-associated-with-lower-risk-of-hearing-loss-in-women
#10
Sharon G Curhan, Molin Wang, Roland D Eavey, Meir J Stampfer, Gary C Curhan
Background: Specific nutrients have been associated with hearing status, but associations between healthful dietary patterns and risk of hearing loss have not been prospectively evaluated. Objective: We sought to prospectively examine the relations between adherence to the Alternate Mediterranean diet (AMED), the Dietary Approaches to Stop Hypertension (DASH), and the Alternative Healthy Eating Index-2010 (AHEI-2010), and risk of hearing loss. Methods: We conducted a longitudinal cohort study (1991-2013) of 81,818 women in the Nurses' Health Study II, aged 27-44 y at baseline...
May 11, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29757226/inflammation-not-cholesterol-is-a-cause-of-chronic-disease
#11
REVIEW
Alexandros Tsoupras, Ronan Lordan, Ioannis Zabetakis
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in relation to the development of chronic diseases have been somewhat demonised. However, the principles of the Mediterranean diet and relevant data linked to the examples of people living in the five blue zones demonstrate that the key to longevity and the prevention of chronic disease development is not the reduction of dietary or serum cholesterol but the control of systemic inflammation. In this review, we present all the relevant data that supports the view that it is inflammation induced by several factors, such as platelet-activating factor (PAF), that leads to the onset of cardiovascular diseases (CVD) rather than serum cholesterol...
May 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29754829/randomization-to-6-month-mediterranean-diet-compared-with-a-low-fat-diet-leads-to-improvement-in-dietary-inflammatory-index-scores-in-patients-with-coronary-heart-disease-the-ausmed-heart-trial
#12
Hannah L Mayr, Colleen J Thomas, Audrey C Tierney, Teagan Kucianski, Elena S George, Miguel Ruiz-Canela, James R Hebert, Nitin Shivappa, Catherine Itsiopoulos
A higher dietary inflammatory index (DII®) score is associated with inflammation and incidence of coronary heart disease (CHD). We hypothesized that a Mediterranean diet (MedDiet) intervention would reduce DII score. We assessed dietary data from a randomized controlled trial comparing 6-month MedDiet versus low-fat diet intervention, in patients with CHD. We aimed to determine the DII scores of the prescribed diets' model meal plans, followed by whether dietary intervention led to lower (i.e., more anti-inflammatory) DII scores and consequently lower high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (hs-IL-6)...
April 14, 2018: Nutrition Research
https://www.readbyqxmd.com/read/29747957/home-exercise-childhood-obesity-intervention-a-randomized-clinical-trial-comparing-print-versus-web-based-move-it-platforms
#13
Alejandro Bruñó, Patricia Escobar, Ausias Cebolla, Julio Álvarez-Pitti, Jaime Guixeres, Empar Lurbe, Rosa Baños, Juan F Lisón
PURPOSE: To compare the impact of adhering to a Mediterranean diet plus mixed physical exercise program (Move-It) implemented by means of printed instructions or via a web-platform (with or without e-mail support) on body composition, physical fitness, and blood pressure. DESIGN AND METHODS: Randomized clinical trial. Fifty-two overweight or obese Spanish children and adolescents were randomly assigned to the print-based (n = 18), Move-It (n = 18), or Move-It plus support (n = 16) intervention groups...
May 7, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29742452/anti-senescence-compounds-a-potential-nutraceutical-approach-to-healthy-aging
#14
REVIEW
Felicia Gurău, Simone Baldoni, Francesco Prattichizzo, Emma Espinosa, Francesco Amenta, Antonio Domenico Procopio, Maria Cristina Albertini, Massimiliano Bonafè, Fabiola Olivieri
The desire of eternal youth seems to be as old as mankind. However, the increasing life expectancy experienced by populations in developed countries also involves a significantly increased incidence of the most common age-related diseases (ARDs). Senescent cells (SCs) have been identified as culprits of organismal aging. Their number rises with age and their senescence-associated secretory phenotype fuels the chronic, pro-inflammatory systemic state (inflammaging) that characterizes aging, impairing the regenerative ability of stem cells and increasing the risk of developing ARDs...
May 6, 2018: Ageing Research Reviews
https://www.readbyqxmd.com/read/29740638/mediterranean-diet-based-intervention-in-pregnancy-to-improve-maternal-and-fetal-outcomes-methodological-challenges-and-lessons-learned-from-the-multicentre-esteem-study
#15
Bassel H Al Wattar, Julie Dodds, Anna Placzek, Eleni Spyreli, Sally Higgins, Amanda Moore, Richard Hooper, Lee Beresford, Tessa J Roseboom, Maira Bes-Rastrollo, Graham Hitman, Khalid S Khan, Shakila Thangaratinam
Introduction: Evaluating complex dietary interventions such as Mediterranean diet in pregnancy presents unique methodological challenges. We present the challenges and the lessons learned from a multicentre randomised trial (ESTEEM) on Mediterranean-based dietary intervention in pregnancy. Methods: We recruited pregnant women who met our predefined inclusion criteria and randomised those with metabolic risk factors to the Mediterranean-based dietary intervention or routine antenatal care...
June 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29735268/evaluation-of-mediterranean-diet-adherence-in-patients-with-a-history-of-coronary-revascularization
#16
B Acar, E Gucuk Ipek, S Unal, C Yayla, M Karanfil, C Burak, M Kara, F Bayraktar, M S Kuyumcu, S Aydogdu
INTRODUCTION: Lifestyle modification is an important component of the secondary prevention strategies; and a healthy diet is one of the cornerstones in management of the coronary heart disease. We aimed to investigate the dietary habits of the patients with history of coronary revascularization, characteristics of the ones with good adherence by using alternate MedDiet questionnaire. METHODS: We included outpatients who had a history of coronary revascularization at least 6 months prior to enrollment...
May 4, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29734769/novel-natural-products-for-healthy-ageing-from-the-mediterranean-diet-and-food-plants-of-other-global-sources-the-medihealth-project
#17
Birgit Waltenberger, Maria Halabalaki, Stefan Schwaiger, Nicolas Adamopoulos, Noureddine Allouche, Bernd L Fiebich, Nina Hermans, Pidder Jansen-Dürr, Victor Kesternich, Luc Pieters, Stefan Schönbichler, Alexios-Leandros Skaltsounis, Hung Tran, Ioannis P Trougakos, Alvaro Viljoen, Jean-Luc Wolfender, Christian Wolfrum, Nikos Xynos, Hermann Stuppner
There is a rapid increase in the percentage of elderly people in Europe. Consequently, the prevalence of age-related diseases will also significantly increase. Therefore, the main goal of MediHealth, an international research project, is to introduce a novel approach for the discovery of active agents of food plants from the Mediterranean diet and other global sources that promote healthy ageing. To achieve this goal, a series of plants from the Mediterranean diet and food plants from other origins are carefully selected and subjected to in silico, cell-based, in vivo (fly and mouse models), and metabolism analyses...
May 6, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29734664/blood-ammonia-as-a-possible-etiological-agent-for-alzheimer-s-disease
#18
REVIEW
Yan Yan Jin, Parul Singh, Hea-Jong Chung, Seong-Tschool Hong
Alzheimer’s disease (AD), characterized by cognitive decline and devastating neurodegeneration, is the most common age-related dementia. Since AD is a typical example of a complex disease that is affected by various genetic and environmental factors, various factors could be involved in preventing and/or treating AD. Extracellular accumulation of beta-amyloid peptide (Aβ) and intracellular accumulation of tau undeniably play essential roles in the etiology of AD. However, interestingly enough, medications targeting Aβ or tau all failed and the only clinically efficient medications for AD are drugs targeting the cholinergic pathway...
May 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29733820/considerations-to-facilitate-a-us-study-that-replicates-predimed
#19
REVIEW
David R Jacobs, Kristina S Petersen, Karianne Svendsen, Emilio Ros, Carol B Sloan, Lyn M Steffen, Linda C Tapsell, Penny M Kris-Etherton
The PREDIMED clinical trial provided strong evidence that a Mediterranean dietary pattern (MedDiet) could help prevent cardiovascular disease (CVD) events in high risk middle-aged/older people. This report considers the feasibility of replicating PREDIMED in the U.S., including recommendations for dietary and behavioral principles. A 14-point Mediterranean Diet Adherence Score (MEDAS) guided the PREDIMED MedDiet recommendations. At baseline MEDAS points were ~8.5. During intervention this score increased to nearly 11 in MedDiet vs...
May 4, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29731626/the-influence-of-disease-severity-and-lifestyle-factors-on-the-peak-annual-25-oh-d-value-of-copd-patients
#20
Magnus Kentson, Per Leanderson, Petra Jacobson, Hans Lennart Persson
Background: The prevalence of individuals deficient in vitamin D (defined as a serum level of the stable metabolite 25(OH)D <50 nmol/L) is increasing in countries with low annual ultraviolet (UV) radiation and among individuals unable to perform outdoor activities, for example, COPD patients. Objective: To assess the role of vitamin D deficiency, independently of seasonal variation, the peak annual value of 25(OH)D was measured in subjects with advanced COPD ± long-term oxygen therapy (LTOT) and lung healthy control subjects...
2018: International Journal of Chronic Obstructive Pulmonary Disease
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