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Health related quality of life africa

Vincent A Adzika, Franklin N Glozah, Desmond Ayim-Aboagye, Collins S K Ahorlu
BACKGROUND: Sickle cell disease (SCD) is of major public health concern globally, with majority of patients living in Africa. Despite its relevance, there is a dearth of research to determine the socio-demographic distribution and psychosocial impact of SCD in Ghana. The objective of this study was to examine the socio-demographic distribution and psychosocial consequences of SCD among patients in Ghana and to assess their quality of life and coping mechanisms. METHODS: A cross-sectional research design was used that involved the completion of questionnaires on socio-demographic characteristics, quality of life, coping mechanisms, anxiety and depression...
January 31, 2017: Journal of Health, Population, and Nutrition
Des Scott, Gillian D Ferguson, Jennifer Jelsma
BACKGROUND: The EQ-5D-Y, an outcome measure of Health Related Quality of Life (HRQoL) in children, was developed by an international task team in 2010. The multinational feasibility, reliability and validity study which followed was undertaken with mainly healthy children. The aim of this study was to investigate the psychometric properties of the EQ-5D-Y when used to assess the HRQoL of children with different health states. METHOD: A sample of 224 children between eight and twelve years were grouped according to their health state...
January 19, 2017: Health and Quality of Life Outcomes
Liezel Ennion, Anton Johannesson, Anthea Rhoda
BACKGROUND: Challenges exist with the provision of appropriate mobility assistive devices in rural areas. The use of the direct manufacturing prosthetic socket system is a possible solution to these challenges. OBJECTIVES: The objective of this study was to test and explore the clients' perspectives with the application of this device. STUDY DESIGN: Within a mixed-methods approach, a longitudinal sequential explanatory design was applied. METHODS: The Orthotic and Prosthetic User's Survey was administered to explore the use of the direct manufacturing prosthetic socket system in terms of function, health-related quality of life and client satisfaction...
January 1, 2017: Prosthetics and Orthotics International
Bradley Y Harris, Matthew F Roth, Bassel G Diebo, Shay Bess, Alexander A Theologis, Justin K Scheer, Frank J Schwab, Virginie Lafage, Christopher P Ames, Richard Hodes, Jennifer Ayamga, Oheneba Boachie-Adjei
STUDY DESIGN: Retrospective analysis of propensity score-matched (PSM) observational cohorts. OBJECTIVES: To evaluate and compare preoperative health-related quality of life (HRQoL) scores and radiographic measurements of young African and US adults with spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: Young ASD patients in the United States are motivated more to correct coronal and sagittal plane deformities than to alleviate pain. Motivations for surgical correction in young ASD patients in Africa have not been previously investigated...
September 2016: Spine Deformity
I Alvarez-Alvarez, H Niu, F Guillen-Grima, I Aguinaga-Ontoso
BACKGROUND: Wheezing affects children's quality of life, and is related with asthma in childhood. Although prevalence of wheezing has been previously studied in several countries, there is no reference of worldwide prevalence in infants. The aim of this meta-analysis is to estimate the prevalence of wheezing and recurrent wheezing in infants aged up to two years, and compare the prevalence across world regions. METHODS: Literature search was conducted in MEDLINE and SCOPUS databases, looking for observational studies published up to June 2016, including as keywords "prevalence" or "epidemiology" combined with "wheeze", "wheezing" or "asthma symptoms" and "infant" or "preschool"...
November 16, 2016: Allergologia et Immunopathologia
Liezel Ennion, Anthea Rhoda
BACKGROUND: Major lower limb amputations result in a significant sense of loss, psychological stress, and decrease in function and overall quality of life for the amputee. The holistic, patient-centered prosthetic rehabilitation of an amputee requires input from a team of dedicated health professionals from different disciplines commonly referred to as a multidisciplinary team (MDT). MDT rehabilitation is considered crucial in the reintegration of the amputee into the community, as well as for providing psychological support after limb loss...
2016: Journal of Multidisciplinary Healthcare
Imade J Ayo-Yusuf, Sudeshni Naidoo
BACKGROUND: Oral pain affects people's daily activities and quality of life. The burden of oral pain may vary across socio-economic positions. Currently, little is known about the social gradient in the cost of oral pain among South Africans. This study therefore assessed the social gradient in the cost of oral pain and the related dental service utilisation pattern among South African adults. METHODS: Data were obtained from a nationally representative cross-sectional survey of South African adults ≥16 year-old (n = 2651) as part of the South African Social Attitudes Survey conducted by the South African Human Sciences Research Council...
November 5, 2016: BMC Oral Health
Eugene T Richardson, Mohamed Bailor Barrie, J Daniel Kelly, Yusupha Dibba, Songor Koedoyoma, Paul E Farmer
Despite more than 25 documented outbreaks of Ebola since 1976, our understanding of the disease is limited, in particular the social, political, ecological, and economic forces that promote (or limit) its spread. In the following study, we seek to provide new ways of understanding the 2013-2016 Ebola pandemic. We use the term, 'pandemic,' instead of 'epidemic,' so as not to elide the global forces that shape every localized outbreak of infectious disease. By situating life histories via a biosocial approach, the forces promoting or retarding Ebola transmission come into sharper focus...
June 2016: Health and Human Rights
(no author information available yet)
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015...
8, 2016: Lancet
Monika R Asnani, Kim R Quimby, Nadia R Bennett, Damian K Francis
BACKGROUND: Sickle cell disease is a group of genetic diseases which is especially prevalent in tropical and subtropical regions; however, forced migration and ongoing population movement have spread it throughout the world, with estimated birth rates reaching 0.49 per 1000 in the Americas, 0.07 per 1000 in Europe, 0.68 per 1000 in South and Southeast Asia, and 10.68 per 1000 in Africa. Life for individuals with sickle cell disease can be affected by repeated acute complications and compounded by progressive organ damage...
October 6, 2016: Cochrane Database of Systematic Reviews
Talita le Roux, Bart Vinck, Iain Butler, Liebie Louw, Leone Nauta, Dani Schlesinger, De Wet Swanepoel
OBJECTIVE: To identify and describe predictors of health-related quality of life (HRQoL) outcomes for adult cochlear implant (CI) recipients in South Africa. DESIGN: A retrospective study of adult CI recipients was conducted and cross-sectional HRQoL outcome data were added at the time of data collection, using the Nijmegen Cochlear Implant Questionnaire (NCIQ). Twenty-two potential predictive factors were identified from the retrospective dataset, including demographic, hearing loss, CI and risk-related factors...
January 2017: International Journal of Audiology
R Daya, Z Bayat, F J Raal
BACKGROUND: Diabetes mellitus (DM) is a chronic metabolic disease that potentially causes debilitating and life-threatening complications, demands a lifestyle change, and has important implications with regard to wellbeing and health-related quality of life (HRQOL). OBJECTIVES: To: (i) determine the HRQOL of a sample of patients with type 2 diabetes; (ii) describe the demographics (age, gender, and smoking and alcohol use) of the population studied; (iii) document the following parameters, which are important in determining the control and severity of type 2 diabetes: (a) glycosylated haemoglobin (HbA1C), (b) total amount of insulin required per day (if on insulin therapy), (c) body mass index (BMI), and (d) exercise compliance; (iv) determine whether there was an association between any or all of the above parameters and the HRQOL of these patients; and (v) determine whether coexisting diseases (hypertension (HT) and dyslipidaemia) were present, and compare HRQOL between diabetic patients with and without these diseases...
September 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Gladys Matseke, Violeta J Rodriguez, Karl Peltzer, Deborah Jones
The aim of the study was to determine the prevalence of intimate partner violence (IPV) and associated factors among pregnant HIV-infected women in primary health care facilities in Nkangala and Gert Sibande districts, Mpumalanga, South Africa. Participants were 673 women who were, on average, 28.39 ± 5.73 years old. Data were collected through Audio Computer Assisted Self Interview (ACASI), and analysed using the IBM Statistical Package for Social Sciences (SPSS). Overall, 56.3% reported having experienced either psychological or physical IPV, and 19...
2016: Journal of Psychology in Africa (south of the Sahara, the Caribbean, and Afro-Latin America)
Pascal Geldsetzer, Katrina Ortblad, Till Bärnighausen
The number of people needing chronic disease care is projected to increase in sub-Saharan Africa as a result of expanding human immunodeficiency virus (HIV) treatment coverage, rising life expectancies, and lifestyle changes. Using nationally representative data of healthcare facilities, Di Giorgio et al. found that many HIV clinics in Kenya, Uganda, and Zambia appear to have considerable untapped capacity to provide care for additional patients. These findings highlight the potential for increasing the efficiency of clinical processes for chronic disease care at the facility level...
2016: BMC Medicine
Jamilah Meghji, Hope Simpson, S Bertel Squire, Kevin Mortimer
BACKGROUND: Tuberculosis is an important risk factor for chronic respiratory disease in resource poor settings. The persistence of abnormal spirometry and symptoms after treatment are well described, but the structural abnormalities underlying these changes remain poorly defined, limiting our ability to phenotype post-TB lung disease in to meaningful categories for clinical management, prognostication, and ongoing research. The relationship between post-TB lung damage and patient-centred outcomes including functional impairment, respiratory symptoms, and health related quality of life also remains unclear...
2016: PloS One
Diana Huis In 't Veld, Supa Pengpid, Robert Colebunders, Linda Skaal, Karl Peltzer
Alcohol use may have a negative impact on the course of HIV disease and the effectiveness of its treatment. We studied patients with HIV who use alcohol and associated socio-demographic, health and psychosocial factors. Outcomes from this study may help in selecting patients from clinical practice with high-risk alcohol use and who are likely to benefit most from alcohol reduction interventions. In a cross sectional study in three primary health care clinics in Pretoria, South Africa, from January 2012 to June 2012, patients with HIV infection were interviewed and patients' medical files were reviewed to obtain data on levels of alcohol use (Alcohol Use Disorder Identification Test), patients' socio-demographic characteristics, HIV-related information, health related quality of life (WHOQoL-HIVBref), internalized AIDS stigma, symptoms of depression and adherence to antiretroviral therapy...
July 21, 2016: International Journal of STD & AIDS
Neil K Mehta, Irma T Elo, Michal Engelman, Diane S Lauderdale, Bert M Kestenbaum
In recent decades, the geographic origins of America's foreign-born population have become increasingly diverse. The sending countries of the U.S. foreign-born vary substantially in levels of health and economic development, and immigrants have arrived with distinct distributions of socioeconomic status, visa type, year of immigration, and age at immigration. We use high-quality linked Social Security and Medicare records to estimate life tables for the older U.S. population over the full range of birth regions...
August 2016: Demography
John A Maluccio, Fan Wu, Redwan B Rokon, Rahul Rawat, Suneetha Kadiyala
HIV-related stigma among persons living with HIV/AIDS (PLHIV) is prevalent throughout sub-Saharan Africa. There is limited evidence, however, on which interventions are effective in reducing it. We used data from a prospective impact evaluation of a 12-month food assistance intervention among 904 antiretroviral therapy (ART)- naïve PLHIV in Uganda to examine the program impact on stigma. Stigma was measured using the comprehensive HASI-P scale, which demonstrated good internal consistency (Cronbach's alpha = 0...
July 2, 2016: AIDS and Behavior
Birgit Fullerton, Andrea Siebenhofer, Klaus Jeitler, Karl Horvath, Thomas Semlitsch, Andrea Berghold, Johannes Plank, Thomas R Pieber, Ferdinand M Gerlach
BACKGROUND: Short-acting insulin analogue use for people with diabetes is still controversial, as reflected in many scientific debates. OBJECTIVES: To assess the effects of short-acting insulin analogues versus regular human insulin in adults with type 1 diabetes. SEARCH METHODS: We carried out the electronic searches through Ovid simultaneously searching the following databases: Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R) (1946 to 14 April 2015), EMBASE (1988 to 2015, week 15), the Cochrane Central Register of Controlled Trials (CENTRAL; March 2015), ClinicalTrials...
June 30, 2016: Cochrane Database of Systematic Reviews
Nicola Mulder, Victoria Nembaware, Adekunle Adekile, Kofi A Anie, Baba Inusa, Biobele Brown, Andrew Campbell, Furahini Chinenere, Catherine Chunda-Liyoka, Vimal K Derebail, Amy Geard, Kais Ghedira, Carol M Hamilton, Neil A Hanchard, Melissa Haendel, Wayne Huggins, Muntaser Ibrahim, Simon Jupp, Karen Kengne Kamga, Jennifer Knight-Madden, Philomène Lopez-Sall, Mamana Mbiyavanga, Deogratias Munube, Damian Nirenberg, Obiageli Nnodu, Solomon Fiifi Ofori-Acquah, Kwaku Ohene-Frempong, Kenneth Babu Opap, Sumir Panji, Miriam Park, Gift Pule, Charmaine Royal, Raphael Sangeda, Bamidele Tayo, Marsha Treadwell, Léon Tshilolo, Ambroise Wonkam
Sickle cell disease (SCD) is a debilitating single gene disorder caused by a single point mutation that results in physical deformation (i.e. sickling) of erythrocytes at reduced oxygen tensions. Up to 75% of SCD in newborns world-wide occurs in sub-Saharan Africa, where neonatal and childhood mortality from sickle cell related complications is high. While SCD research across the globe is tackling the disease on multiple fronts, advances have yet to significantly impact on the health and quality of life of SCD patients, due to lack of coordination of these disparate efforts...
June 2016: Applied & Translational Genomics
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