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https://www.readbyqxmd.com/read/29771779/cost-of-integrating-non-communicable-disease-screening-into-home-based-hiv-testing-and-counseling-in-south-africa
#1
Ilya Golovaty, Monisha Sharma, Alastair Van Heerden, Heidi van Rooyen, Jared M Baeten, Connie Celum, Ruanne V Barnabas
INTRODUCTION: Integrated HIV-non-communicable disease (NCD) services have the potential to avert death and disability, but require data on program costs to assess the impact of integrated services on affordability. METHODS: We estimated the incremental costs of NCD screening as part of home-based HIV testing and counseling (HTC) and referral to care in KwaZulu-Natal, South Africa. All adults in the households were offered integrated HIV-NCD screening (for HIV, diabetes, hypertension, hypercholesterolemia, obesity, depression, tobacco and alcohol use), counseling, and linkage to care...
May 10, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29723253/why-some-women-fail-to-give-birth-at-health-facilities-a-comparative-study-between-ethiopia-and-nigeria
#2
Sanni Yaya, Ghose Bishwajit, Olalekan A Uthman, Agbessi Amouzou
BACKGROUND: Obstetric complications and maternal deaths can be prevented through safe delivery process. Facility based delivery significantly reduces maternal mortality by increasing women's access to skilled personnel attendance. However, in sub-Saharan Africa, most deliveries take place without skilled attendants and outside health facilities. Utilization of facility-based delivery is affected by socio-cultural norms and several other factors including cost, long distance, accessibility and availability of quality services...
2018: PloS One
https://www.readbyqxmd.com/read/29567495/characterizing-exposure-to-household-air-pollution-within-the-prospective-urban-rural-epidemiology-pure-study
#3
Raphael E Arku, Aaron Birch, Matthew Shupler, Salim Yusuf, Perry Hystad, Michael Brauer
BACKGROUND: Household air pollution (HAP) from combustion of solid fuels is an important contributor to disease burden in low- and middle-income countries (LIC, and MIC). However, current HAP disease burden estimates are based on integrated exposure response curves that are not currently informed by quantitative HAP studies in LIC and MIC. While there is adequate evidence supporting causal relationships between HAP and respiratory disease, large cohort studies specifically examining relationships between quantitative measures of HAP exposure with cardiovascular disease are lacking...
May 2018: Environment International
https://www.readbyqxmd.com/read/29543818/economic-costs-and-health-related-quality-of-life-outcomes-of-hospitalised-patients-with-high-hiv-prevalence-a-prospective-hospital-cohort-study-in-malawi
#4
Hendramoorthy Maheswaran, Stavros Petrou, Danielle Cohen, Peter MacPherson, Felistas Kumwenda, David G Lalloo, Elizabeth L Corbett, Aileen Clarke
INTRODUCTION: Although HIV infection and its associated co-morbidities remain the commonest reason for hospitalisation in Africa, their impact on economic costs and health-related quality of life (HRQoL) are not well understood. This information is essential for decision-makers to make informed choices about how to best scale-up anti-retroviral treatment (ART) programmes. This study aimed to quantify the impact of HIV infection and ART on economic outcomes in a prospective cohort of hospitalised patients with high HIV prevalence...
2018: PloS One
https://www.readbyqxmd.com/read/29450195/insecticide-treated-nets-utilization-and-associated-factors-among-under-5-years-old-children-in-mirab-abaya-district-gamo-gofa-zone-ethiopia
#5
Amha Admasie, Amanuel Zemba, Wondimagegn Paulos
Background: Malaria can be prevented using cost-effective interventions. It can be prevented at large via the use of insecticide-treated mosquito nets (ITNs). The use of ITNs decreases malaria mortality rates by 55% in under-5 years old children in Africa, Ethiopia, realizing the effectiveness, scaling up distribution and utilization of ITNs to cover 100% of children less than 5 years of age. However, little is known about ITNs utilization and factors associated with the utilization in under-5 years old children in the study area yet...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29408895/systematic-review-of-school-tobacco-prevention-programs-in-african-countries-from-2000-to-2016
#6
REVIEW
Akihiro Nishio, Junko Saito, Sachi Tomokawa, Jun Kobayashi, Yuka Makino, Takeshi Akiyama, Kimihiro Miyake, Mayumi Yamamoto
BACKGROUND: The World Bank has reported that global smoking rates declined from 2000 to 2012, with the only exception found in males in Sub-Saharan Africa. Sub-Saharan Africa is considered to be in stage one of the tobacco epidemic continuum. To address this problem, school-based programs for smoking prevention are considered cost-effective and promising. Since tobacco prevention programs are influenced by social competence or customs of each country, tobacco prevention programs that have success in Western countries are not always effective in African countries...
2018: PloS One
https://www.readbyqxmd.com/read/29368531/exploratory-study-of-the-dispensing-patterns-of-vaccines-by-a-sample-of-community-pharmacies-in-southern-africa
#7
Ilse Truter
Vaccination is one of the most cost-effective healthcare interventions. Pharmacies in South Africa provide a vaccination service where childhood immunizations, some travel vaccines and vaccines for specific populations are dispensed and administered, but little has been published on which vaccines are dispensed and at what cost. Areas covered: This retrospective drug utilization study determined the dispensing patterns of vaccines in community pharmacies during 2015 with the focus on the types and cost of vaccines dispensed in ATC group J07...
January 25, 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/29360841/does-directly-administered-antiretroviral-therapy-represent-good-value-for-money-in-sub-saharan-africa-a-cost-utility-and-value-of-information-analysis
#8
Rashidah T Uthman, Andrew J Sutton, Louise J Jackson, Olalekan A Uthman
BACKGROUND: Successful antiretroviral therapy (ART) relies on the optimal level of ART adherence to achieve reliable viral suppression, avert HIV drug resistance, and prevent avoidable deaths. It has been shown that there are various groups of people living with HIV at high-risk of non-adherence to ART in sub-Saharan Africa. The objective of this study was to examine the cost effectiveness and value-of-information of directly administered antiretroviral therapy (DAART) versus self-administered ART among people living with HIV, at high risk of non-adherence to ART in sub-Saharan Africa...
2018: PloS One
https://www.readbyqxmd.com/read/29347849/joint-pain-within-adult-middle-aged-women-attending-a-community-clinic-in-a-peri-urban-area-in-south-africa-a-cross-sectional-survey
#9
Roline Barnes, Jennifer Jelsma, Romy Parker
BACKGROUND: This study aimed to investigate the prevalence of joint pain in women between the ages of 40 and 64 years who attended a community clinic in the Free State to provide micro-information for health care planners. METHODS: A sample of convenience was utilized in the cross-sectional survey. Health care workers were recruited to conduct the survey. Outcome measures included the Community-Oriented-Programme-For-The-Control-Of-Rheumatic-Disease questionnaire and European Quality of Life - 5 Dimensions health related quality of life measure...
January 19, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29316917/an-observational-analysis-of-the-impact-of-indoor-residual-spraying-with-non-pyrethroid-insecticides-on-the-incidence-of-malaria-in-s%C3%A3-gou-region-mali-2012-2015
#10
Joseph Wagman, Christelle Gogue, Kenzie Tynuv, Jules Mihigo, Elie Bankineza, Mamadou Bah, Diadier Diallo, Andrew Saibu, Jason H Richardson, Diakalkia Kone, Seydou Fomba, Jeff Bernson, Richard Steketee, Laurence Slutsker, Molly Robertson
BACKGROUND: Ségou Region in Central Mali is an area of high malaria burden with seasonal transmission, high access to and use of long-lasting insecticidal nets (LLINs), and resistance to pyrethroids and DDT well documented in Anopheles gambiae s.l. (the principal vector of malaria in Mali). Ségou has recently received indoor residual spraying (IRS) supported by Mali's collaboration with the US President's Malaria Initiative/Africa Indoor Residual Spraying programme. From 2012 to 2015, two different non-pyrethroid insecticides: bendiocarb in 2012 and 2013 and pirimiphos-methyl in 2014 and 2015, were used for IRS in two districts...
January 10, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29309556/statistics-on-the-use-of-cardiac-electronic-devices-and-interventional-electrophysiological-procedures-in-africa-from-2011-to-2016-report-of-the-pan-african-society-of-cardiology-pascar-cardiac-arrhythmias-and-pacing-task-forces
#11
Aimé Bonny, Marcus Ngantcha, Mohamed Jeilan, Emmy Okello, Bundhoo Kaviraj, Mohammed A Talle, George Nel, Eloi Marijon, Mahmoud U Sani, Zaheer Yousef, Kamilu M Karaye, Ibrahim A Touré, Mohamed A Awad, George Millogo, Jonas Kologo, Adama Kane, Romain Houndolo, Anastase Dzudié, Amam Mbakwem, Bongani M Mayosi, Ashley Chin
Aims: To provide comprehensive information on the access and use of cardiac implantable electronic devices (CIED) and catheter ablation procedures in Africa. Methods and results: The Pan-African Society of Cardiology (PASCAR) collected data on invasive management of cardiac arrhythmias from 2011 to 2016 from 31 African countries. A specific template was completed by physicians, and additional information obtained from industry. Information on health care systems, demographics, economics, procedure rates, and specific training programs was collected...
December 21, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29300755/incremental-cost-effectiveness-of-screening-and-laser-treatment-for-diabetic-retinopathy-and-macular-edema-in-malawi
#12
Damir Vetrini, Christine A Kiire, Philip I Burgess, Simon P Harding, Petros C Kayange, Khumbo Kalua, Gerald Msukwa, Nicholas A V Beare, Jason Madan
OBJECTIVE: To investigate the economic impact of introducing targeted screening and laser photocoagulation treatment for sight-threatening diabetic retinopathy and macular edema in a setting with no previous screening or laser treatment for diabetic retinopathy in sub-Saharan Africa. MATERIALS AND METHODS: A cohort Markov model was built to compare combined targeted screening and laser treatment for patients with sight-threatening diabetic retinopathy and macular edema against no intervention...
2018: PloS One
https://www.readbyqxmd.com/read/29121482/feasibility-of-coupling-a-thermal-optical-carbon-analyzer-to-a-quadrupole-mass-spectrometer-for-enhanced-pm2-5-speciation
#13
Gustavo M Riggio, Judith C Chow, Paul M Cropper, Xiaoliang Wang, Reddy L N Yatavelli, Xufei Yang, John G Watson
A thermal/optical carbon analyzer (TOA), normally used for quantification of organic carbon (OC) and elemental carbon (EC) in PM2.5 speciation networks, was adapted to direct thermally-evolved gases to an electron impact quadrupole mass spectrometer (QMS), creating a TOA-QMS. This approach produces spectra similar to those obtained by the Aerodyne Aerosol Mass Spectrometer (AMS), but the ratios of the mass to charge (m/z) signals differ and must be re-measured using laboratory-generated standards. Linear relationships are found between TOA-QMS signals and ammonium (NH4(+)), nitrate (NO3(-)), and sulfate (SO4(2-)) standards...
November 9, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29020295/improved-retention-with-6-month-clinic-return-intervals-for-stable-human-immunodeficiency-virus-infected-patients-in-zambia
#14
Aaloke Mody, Monika Roy, Kombatende Sikombe, Thea Savory, Charles Holmes, Carolyn Bolton-Moore, Nancy Padian, Izukanji Sikazwe, Elvin Geng
Background: Extending appointment intervals for stable HIV-infected patients in sub-Saharan Africa can reduce patient opportunity costs and decongest overcrowded facilities. Methods: We analyzed a cohort of stable HIV-infected adults (on treatment with CD4 >200 cells/μL for more than 6 months) who presented for clinic visits in Lusaka, Zambia. We used multilevel, mixed-effects logistic regression adjusting for patient characteristics, including prior retention, to assess the association between scheduled appointment intervals and subsequent missed visits (>14 days late to next visit), gaps in medication (>14 days late to next pharmacy refill), and loss to follow-up (LTFU; >90 days late to next visit)...
January 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28991025/the-costs-of-hiv-treatment-and-care-in-ghana
#15
Evelinn Mikkelsen, Jan A C Hontelez, Justice Nonvignon, Sam Amon, Felix A Asante, Moses K Aikins, Julie van de Haterd, Rob Baltussen
OBJECTIVE: To determine cost functions that describe the dynamics of costs of HIV treatment and care in Ghana by CD4 cell count at treatment initiation and over time on antiretroviral therapy (ART). DESIGN: We used detailed longitudinal healthcare utilization data from clinical health records of HIV-infected patients at seven Ghanaian ART clinics to estimate cost functions of treatment and care by CD4 cell count at treatment initiation and time on ART. METHODS: We developed two linear regression models; one with individual random effects to determine the relationship between CD4 cell count at ART initiation and costs of treatment and care, and one with individual fixed effects to determine the causal effect of time in care on costs of treatment and care...
October 23, 2017: AIDS
https://www.readbyqxmd.com/read/28985730/clinical-utility-of-the-low-density-infinium-qc-genotyping-array-in-a-genomics-based-diagnostics-laboratory
#16
Petr Ponomarenko, Alex Ryutov, Dennis T Maglinte, Ancha Baranova, Tatiana V Tatarinova, Xiaowu Gai
BACKGROUND: With 15,949 markers, the low-density Infinium QC Array-24 BeadChip enables linkage analysis, HLA haplotyping, fingerprinting, ethnicity determination, mitochondrial genome variations, blood groups and pharmacogenomics. It represents an attractive independent QC option for NGS-based diagnostic laboratories, and provides cost-efficient means for determining gender, ethnic ancestry, and sample kinships, that are important for data interpretation of NGS-based genetic tests. METHODS: We evaluated accuracy and reproducibility of Infinium QC genotyping calls by comparing them with genotyping data of the same samples from other genotyping platforms, whole genome/exome sequencing...
October 6, 2017: BMC Medical Genomics
https://www.readbyqxmd.com/read/28972982/feasibility-of-utilizing-the-sd-bioline-onchocerciasis-igg4-rapid-test-in-onchocerciasis-surveillance-in-senegal
#17
Yakou Dieye, Helen L Storey, Kelsey L Barrett, Emily Gerth-Guyette, Laura Di Giorgio, Allison Golden, Dunia Faulx, Michael Kalnoky, Marie Khemesse Ngom Ndiaye, Ngayo Sy, Malang Mané, Babacar Faye, Mamadou Sarr, Elhadji Mamadou Dioukhane, Roger B Peck, Philippe Guinot, Tala de Los Santos
As effective onchocerciasis control efforts in Africa transition to elimination efforts, different diagnostic tools are required to support country programs. Senegal, with its long standing, successful control program, is transitioning to using the SD BIOLINE Onchocerciasis IgG4 (Ov16) rapid test over traditional skin snip microscopy. The aim of this study is to demonstrate the feasibility of integrating the Ov16 rapid test into onchocerciasis surveillance activities in Senegal, based on the following attributes of acceptability, usability, and cost...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28900370/utility-of-routine-laboratory-preoperative-tests-based-on-previous-results-time-to-give-up
#18
Enrique Rodríguez-Borja, Africa Corchon-Peyrallo, Gerardo Aguilar-Aguilar, Arturo Carratala-Calvo
INTRODUCTION: The usefulness and cost-effectiveness of routine laboratory preoperative tests (POTs) have been challenged recently. In fact, the American Society of Anesthesiologists (ASA) Task Force has stated that test results obtained from the medical record within 6 months of surgery generally are mostly acceptable. The aim of our study was to evaluate the degree of utility of POTs and their clinical benefit based on this recommendation. MATERIAL AND METHODS: We studied retrospectively every routine POT request from 8 randomly selected weeks in 2016...
October 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28875531/pathogen-reduction-of-whole-blood-utility-and-feasibility
#19
REVIEW
J-P Allain, R Goodrich
OBJECTIVES: To collect information on pathogen reduction applied to whole blood. BACKGROUND: Pathogen reduction (PR) of blood components has been developed over the past two decades, and pathogen-reduced fresh-frozen plasma and platelet concentrates are currently in clinical use. High cost and incomplete coverage of components make PR out of reach for low- and middle-income countries (LMIC). However, should PR become applicable to whole blood (WB), the main product transfused in sub-Saharan Africa, and be compatible with the preparation of clinically suitable components, cost would be minimised, and a range of safety measures in place at high cost in developed areas would become redundant...
October 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28870567/tele-neurology-in-sub-saharan-africa-a-systematic-review-of-the-literature
#20
REVIEW
Fred S Sarfo, Sheila Adamu, Dominic Awuah, Bruce Ovbiagele
BACKGROUND: The rapid advancement in telecommunications on the African continent has opened up avenues for improving medical care to underserved populations. Although the greatest burden of neurological disorders is borne by Low-and-Middle Income Countries (LMICs) including sub-Saharan Africa (SSA), there is a profound paucity of neurologists to serve the population. Telemedicine presents a promising avenue for effective mobilization and utilization of the few neurologists in Africa. OBJECTIVE: To systematically review the published literature on the use of telemedicine for improved care and outcomes for patients with neurological disorders in SSA...
September 15, 2017: Journal of the Neurological Sciences
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