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Economic evaluation congenital heart disease

Aziz Rezapour, Saeed Bagheri Faradonbeh, Vahid Alipour, Mani Yusefvand
BACKGROUND: Cardiomyopathies is a group of heart diseases that directly affects the heart muscle, and their causes is not just high blood pressure, congenital and pericardial diseases but ischemic cardiomyopathy disease are also caused by vascular disorders, and to confirm the diagnosis, angiography is required. There are several methods for treating and controlling ischemic cardiomyopathy in world health systems and especially in the Iran health system, which include medical treatment, percutaneous coronary intervention (PCI), and coronary artery bypass graft (CABG)...
March 2018: Medicine (Baltimore)
Josepheen De Asis-Cruz, Mary T Donofrio, Gilbert Vezina, Catherine Limperopoulos
Newborns with congenital heart disease (CHD) requiring open heart surgery are at increased risk for neurodevelopmental disabilities. Recent quantitative MRI studies have reported disrupted growth, microstructure, and metabolism in fetuses and newborns with complex CHD. To date, no study has examined whether functional brain connectivity is altered in this high-risk population after birth, before surgery. Our objective was to compare whole-brain functional connectivity of resting state networks in healthy, term newborns (n = 82) and in term neonates with CHD before surgery (n = 30) using graph theory and network-based statistics...
2018: NeuroImage: Clinical
Muhammet Fatih Kilinc, Sedat Cakmak, Demirhan Orsan Demir, Omer Gokhan Doluoglu, Yildiray Yildiz, Kaya Horasanli, Ayhan Dalkilic
INTRODUCTION: The association between ambient temperature that the mother is exposed to during pregnancy and hypospadias has not been investigated by the studies, although the recent studies showed the correlation between some congenital malformations (congenital heart disease, neural tube defect, etc.) and ambient temperature. OBJECTIVE: The aim was to investigate the relation between hypospadias and the ambient temperatures that the mother is exposed to during her pregnancy...
December 2016: Journal of Pediatric Urology
Ewa-Lena Bratt, Stina Järvholm, Britt-Marie Ekman-Joelsson, Lars-Åke Mattson, Mats Mellander
BACKGROUND: Prenatal screening for foetal cardiac abnormalities has been increasingly practiced in Sweden during the last 25 years. A prenatal diagnosis may have medical benefits but may also cause sustained parental psychological distress. The aim of this study was to explore pregnant women's, and their partner's, experiences of counselling and need for support during continued pregnancy following a prenatal diagnosis of a cardiac defect. A second aim was to use this information to propose a structured follow-up programme for continued support after the first counselling...
2015: BMC Pregnancy and Childbirth
Bertin Dibi Kouame, Isabelle Ama N'guetta-Brou, Guy Serge Yapo Kouame, Moufidath Sounkere, Maxime Koffi, Jean Baptiste Yaokreh, Thierry Odehouri-Koudou, Samba Tembely, Gaudens Atafi Dieth, Ossenou Ouattara, Ruffin Dick
BACKGROUND: Congenital abnormalities constitute one of the major causes of infant mortality, particularly in developing countries. The aim of this study was to describe the epidemiology of congenital anomalies in Cote d'Ivoire. MATERIALS AND METHODS: It was a multicentric study of three academic hospitals and the Heart Institute of Abidjan over 10 years. The epidemiologic Data concerned the Parturients, the annual frequency of congenital abnormalities. Distribution of the congenital abnormalities according to the organs, overall mortality and lethality of congenital abnormalities were evaluated...
January 2015: African Journal of Paediatric Surgery: AJPS
Cora Peterson, Scott D Grosse, Jill Glidewell, Lorraine F Garg, Kim Van Naarden Braun, Mary M Knapp, Leslie M Beres, Cynthia F Hinton, Richard S Olney, Cynthia H Cassell
OBJECTIVE: Critical congenital heart disease (CCHD) was recently added to the U.S. Recommended Uniform Screening Panel for newborns. This evaluation aimed to estimate screening time and hospital cost per newborn screened for CCHD using pulse oximetry as part of a public health economic assessment of CCHD screening. METHODS: A cost survey and time and motion study were conducted in well-newborn and special/intensive care nurseries in a random sample of seven birthing hospitals in New Jersey, where the state legislature mandated CCHD screening in 2011...
January 2014: Public Health Reports
Julius A Ogeng'o, Patrick M Gatonga, Beda O Olabu, Diana K Nyamweya, Dennis Ong'era
BACKGROUND: Heart failure in children is a common cause of morbidity and mortality, with high socio-economic burden. Its pattern varies between countries but reports from Africa are few. The data are important to inform management and prevention strategies. OBJECTIVE: To describe the pattern of congestive heart failure in a Kenyan paediatric population. METHODS: This was a retrospective study done at Kenyatta National Hospital, Nairobi Kenya...
May 2013: Cardiovascular Journal of Africa
Stefan Orwat, Gerhard-Paul Diller, Helmut Baumgartner
Major advances in noninvasive imaging of adult congenital heart disease have been accomplished. These tools play now a key role in comprehensive diagnostic work-up, decision for intervention, evaluation for the suitability of specific therapeutic options, monitoring of interventions and regular follow-up. Besides echocardiography, magnetic resonance (CMR) and computed tomography (CT) have gained particular importance. The choice of imaging modality has thus become a critical issue. This review summarizes strengths and limitations of the different imaging modalities and how they may be used in a complementary fashion...
January 2014: European Heart Journal Cardiovascular Imaging
Massimiliano Cantinotti, Nadia Assanta, Bruno Murzi, Leo Lopez
Haemodynamically insignificant left-to-right shunts are frequently discovered when screening for congenital heart disease, resulting in significant economic and psychosocial impact. A literature search was performed within the National Library of Medicine using the keywords small/insignificant/silent atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA) and patent foramen ovale (PFO). The search was refined by adding the keywords definition, classification and follow-up...
February 2014: Heart: Official Journal of the British Cardiac Society
Tea Andabaka, Jason W Nickerson, Maria Ximena Rojas-Reyes, Juan David Rueda, Vesna Bacic Vrca, Bruno Barsic
BACKGROUND: Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing acute respiratory infections in children. It results in about 3.4 million hospitalisations annually in children under five. Palivizumab is an anti-RSV monoclonal antibody, administered intramuscularly at a dose of 15 mg/kg once every 30 days. The efficacy and safety of palivizumab has been evaluated in multicentre, randomised controlled trials (RCTs) and a large number of economic evaluations (EEs) have tested its cost-effectiveness...
2013: Cochrane Database of Systematic Reviews
M Westwood, M Al, L Burgers, K Redekop, S Lhachimi, N Armstrong, H Raatz, K Misso, J Severens, J Kleijnen
BACKGROUND: Computed tomography (CT) is important in diagnosing and managing many conditions, including coronary artery disease (CAD) and congenital heart disease. Current CT scanners can very accurately diagnose CAD requiring revascularisation in most patients. However, imaging technologies have developed rapidly and new-generation computed tomography (NGCCT) scanners may benefit patients who are difficult to image (e.g. obese patients, patients with high or irregular heart beats and patients who have high levels of coronary calcium or a previous stent or bypass graft)...
2013: Health Technology Assessment: HTA
J M Hussman, K L Lanctôt, B Paes
OBJECTIVE: To review and summarize the literature concerning the cost-effectiveness of palivizumab compared to no prophylaxis in infants and young children with congenital heart disease (CHD). METHODS: A systematic literature search (MEDLINE to March 2012, limited to English language) identified studies that examined the cost-effectiveness of palivizumab in CHD populations. The quality of each study was assigned a quality score of 1-100 based on the Quality of Health Economic Studies (QHES) instrument...
2013: Journal of Medical Economics
Gamze Demirel, Basak Tezel, Sema Ozbas, Serife Suna Oguz, Omer Erdeve, Nurdan Uras, Ugur Dilmen
Our aim was to assess trends in neonatal mortality in 2009, evaluate advances in health policy, determine new goals to preserve a higher quality health service, and to prevent neonatal deaths. Data were gathered from the system of the General Directorate of Mother and Child and Family Planning. Maternal age, birth weight, gestational week, delivery at a health center, delivery by trained assistant, antenatal visits, and cause of death were evaluated. The neonatal mortality rate was 10/1,000 in Turkey in 2009, significantly better than rates of 26 in 1998, 17 in 2003, and 13 in 2008...
September 2013: Maternal and Child Health Journal
Bahareh Eslami, Orjan Sundin, Gloria Macassa, Hamid Reza Khankeh, Joaquim J F Soares
BACKGROUND: Providing appropriate care for adults with congenital heart disease requires the evaluation of their current situation. There is limited research in Iran about these patients, particularly in relation to gender differences in the demographic/socio-economic and lifestyle factors, as well as disease parameters. MATERIALS AND METHODS: The sample consisted of 347 congenital heart disease patients in the age group of 18–64 years, including 181 women, assessed by an analytical cross-sectional study...
April 2013: Cardiology in the Young
Kevin C Harris, Aslam H Anis, Marsha C Crosby, Laurie M Cender, James E Potts, Derek G Human
BACKGROUND: Respiratory syncytial virus (RSV) is a common cause of bronchiolitis in infants. In children with congenital heart disease (CHD), it is associated with significant morbidity and mortality. Palivizumab is a monoclonal antibody that reduces the number of RSV-associated hospitalizations in children with CHD. We sought to assess cost savings and cost-effectiveness of palivizumab in children < 2 years old with hemodynamically significant CHD in a provincially administered RSV prophylaxis program...
July 2011: Canadian Journal of Cardiology
W E Sadoh, D U Nwaneri, A C Owobu
OBJECTIVE: To evaluated the economic burden to families of managing chronic heart failure in children with congenital heart disease. MATERIALS AND METHODS: This longitudinal study was conducted over a year. The families of children with congenital heart disease who were being managed for chronic heart failure in the clinic were recruited for the study. With the aid of a structured questionnaire, data were collected on a monthly basis for three consecutive months, on the family's monthly income, cost of anti-failure medicines, transportation and the number of man-hours spent on clinic visitation...
January 2011: Nigerian Journal of Clinical Practice
Christian Hampp, Teresa L Kauf, Arwa S Saidi, Almut G Winterstein
OBJECTIVES: To evaluate the cost-effectiveness of immunoprophylaxis against respiratory syncytial virus (RSV) infections with palivizumab based on actual cost and observed incidence rates in various pediatric risk groups. DESIGN: Decision tree analysis comparing children with various combinations of the following indications: chronic lung disease, congenital heart disease, or prematurity (≤32 weeks gestation), and children with none of these indications. One-way sensitivity analyses and Monte Carlo simulations were used to quantify parameter uncertainty...
June 2011: Archives of Pediatrics & Adolescent Medicine
D Wang, S Bayliss, C Meads
BACKGROUND: Respiratory syncytial virus (RSV) is a seasonal infectious disease, with epidemics occurring annually from October to March in the UK. It is a very common infection in infants and young children and can lead to hospitalisation, particularly in those who are premature or who have chronic lung disease (CLD) or congenital heart disease (CHD). Palivizumab (Synagis®, MedImmune) is a monoclonal antibody designed to provide passive immunity against RSV and thereby prevent or reduce the severity of RSV infection...
January 2011: Health Technology Assessment: HTA
N Sinzobahamvya, T Kopp, J Photiadis, C Arenz, E Schindler, C Haun, V Hraska, B Asfour
BACKGROUND: Hospital costs are expected to correlate with clinical complexity. Do costs for congenital heart surgery correlate with Aristotle complexity scores? METHODS: 442 inpatient stays in 2008 were evaluated. Aristotle scores and levels were determined. Costs were estimated according to the German Institute for Hospital Reimbursement system. Pearson and Spearman R correlation coefficients and corresponding goodness-of-fit regression coefficients R2 were calculated...
September 2010: Thoracic and Cardiovascular Surgeon
Renata Gomes, Renata Rossi, Sónia Lima, Pedro Carmo, Rui Ferreira, Isabel Menezes, Rui Anjos, Ana Teixeira, João Rosa, José Matono, Paula Maciel, Maynone Martins
BACKGROUND: A telemedicine program was initiated in November 2000 between the Pediatric Cardiology Department of a tertiary care hospital in Lisbon and pediatricians and obstetricians from three remote Portuguese hospitals: two in mainland Portugal and one in the Azores. Images were transmitted by a telemedicine link over three integrated service digital network (ISDN) lines to a regional pediatric cardiology unit for interpretation by a consultant pediatric cardiologist. METHODS: We performed a retrospective review of all teleconsultations at our Department between November 2000 and December 2007...
February 2010: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
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