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https://www.readbyqxmd.com/read/28231685/unmet-psychosocial-needs-in-adolescents-with-inflammatory-bowel-disease
#1
(no author information available yet)
BACKGROUND: Inflammatory bowel diseases (IBD) are severe medical conditions with adverse impact on the quality of life of both children and their caregivers. IBD are associated with many limitations in personal and interpersonal functioning, and it also restricts the patients' ability to use the full potential (extent) of their capabilities. With the progress and humanization in society, the issue of patients' needs became an important topic; however, the psychosocial functioning and quality of life of adolescents suffering from IBD and their caregivers have been understudied...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231682/unmet-needs-of-the-patients-with-obsessive-compulsive-disorder
#2
(no author information available yet)
BACKGROUND: Obsessive compulsive disorder (OCD) is a disabling mental disorder with the chronic and difficult course. The disorder is accompanied by numerous limitations in personal and interpersonal functioning. OCD decreases the quality of life and the chance to maintain relationships and professional status. The patients with OCD often experience a severe disabling course of the disorder. Even the individuals, who follow treatment advice, are often still highly symptomatic. In the last decade, the concept of the needs has been assessed as an extent of the traditional outcome evaluation in order to focus on the identification of the specific needs of the patients and their relatives, improve the patients´ overall mental condition and quality of life, and also to increase the treatment effectiveness of the mental disorders...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231680/-a-review-on-the-advancement-of-internet-based-public-health-surveillance-program
#3
Y Q Zhao, W J Ma
Internet data is introduced into public health arena under the features of fast updating and tremendous volume. Mining and analyzing internet data, researchers can model the internet-based surveillance system to assess the distribution of health-related events. There are two main types of internet-based surveillance systems, i.e. active and passive, which are distinguished by the sources of information. Through passive surveillance system, information is collected from search engine and social media while the active system gathers information through provision of the volunteers...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231677/-a-systematic-review-of-worldwide-natural-history-models-of-colorectal-cancer-classification-transition-rate-and-a-recommendation-for-developing-chinese-population-specific-model
#4
Z F Li, H Y Huang, J F Shi, C G Guo, S M Zou, C C Liu, Y Wang, L Wang, S L Zhu, S L Wu, M Dai
Objective: To review the worldwide studies on natural history models among colorectal cancer (CRC), and to inform building a Chinese population-specific CRC model and developing a platform for further evaluation of CRC screening and other interventions in population in China. Methods: A structured literature search process was conducted in PubMed and the target publication dates were from January 1995 to December 2014. Information about classification systems on both colorectal cancer and precancer on corresponding transition rate, were extracted and summarized...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231642/meniscal-transplants-and-scaffolds-a-systematic-review-of-the-literature
#5
REVIEW
Sean Dangelmajer, Filippo Familiari, Roberto Simonetta, Mehmet Kaymakoglu, Gazi Huri
The reported incidence of meniscal tears is approximately 61 per 100,000. In instances where preservation of the native meniscus is no longer a feasible option, meniscal allograft transplantation (MAT) and implants or scaffolds may be considered. The goal of this review was to compare the success and failure rates of two techniques, MAT and meniscal scaffolds, and make an inference which treatment is more preferable at the present time and future. Studies that met inclusion criteria were assessed for technique used, type of transplant used, number of procedures included in the study, mean age of patients, mean follow-up time, number of failures, failure rate, and reported reoperation rate...
March 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28231639/cell-cycle-rna-regulons-coordinating-early-lymphocyte-development
#6
REVIEW
Alison Galloway, Martin Turner
Lymphocytes undergo dynamic changes in gene expression as they develop from progenitor cells lacking antigen receptors, to mature cells that are prepared to mount immune responses. While transcription factors have established roles in lymphocyte development, they act in concert with post-transcriptional and post-translational regulators to determine the proteome. Furthermore, the post-transcriptional regulation of RNA regulons consisting of mRNAs whose protein products act cooperatively allows RNA binding proteins to exert their effects at multiple points in a pathway...
February 23, 2017: Wiley Interdisciplinary Reviews. RNA
https://www.readbyqxmd.com/read/28231637/preen-oil-and-bird-fitness-a-critical-review-of-the-evidence
#7
Gregorio Moreno-Rueda
The uropygial gland is a holocrine complex exclusive to birds that produces an oleaginous secretion (preen oil) whose function is still debated. Herein, I examine critically the evidence for the many hypotheses of potential functions of this gland. The main conclusion is that our understanding of this gland is still in its infancy. Even for functions that are considered valid by most researchers, real evidence is scarce. Although it seems clear that preen oil contributes to plumage maintenance, we do not know whether this is due to a role in reducing mechanical abrasion or in reducing feather degradation by keratinophilic organisms...
February 23, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28231630/the-role-of-the-family-in-supporting-the-self-management-of-chronic-conditions-a-qualitative-systematic-review
#8
Whitehead Lisa, Towell Amanda, Abu-Qamar Ma'en, Cole-Heath Amanda
AIMS AND OBJECTIVES: To explore the contribution of family members in promoting and supporting the self-management of chronic conditions among adult family members. BACKGROUND: The prevalence of chronic disease continues to grow globally. The role of the family in chronic condition management and support for self-management has received little attention. DESIGN: A systematic review of qualitative literature using the Joanna Briggs Institute approach for qualitative systematic reviews...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231624/targets-and-mechanisms-in-prevention-of-parkinson-s-disease-through-immunomodulatory-treatments
#9
REVIEW
Marianne von Euler Chelpin, Thomas Vorup-Jensen
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the world, however, there is no cure for it. Current treatments only relieve some of the symptoms, without ceasing the disease, and lose efficacy with prolonged treatment. Considerable evidence shows that persistent inflammatory responses, involving T cell infiltration and glial cell activation, are common characteristics of human patients and play a crucial role in the degeneration of dopaminergic neurons. Therefore, it is important to develop therapeutic strategies that can impede or halt the disease through the modulation of the peripheral immune system by aiming at controlling the existing neuroinflammation...
February 23, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28231623/compassion-fatigue-in-nurses-a-metasynthesis
#10
Anna G W Nolte, Charlene Downing, Annie Temane, Marie Hastings-Tolsma
AIM: The purpose of this research was to interpret the body of qualitative work focusing on compassion fatigue to distill a common understanding that could then be applied to nursing care. BACKGROUND: Complex demands place extraordinary stress on nurses struggling to work in overburdened healthcare systems. The result can be the inability to care well for others, leading to compassion fatigue, burnout, and increased numbers leaving the profession. Meta-synthesis offers a means of more fully illuminating compassion fatigue and further understanding of practices which might reduce its negative consequences...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231607/position-in-the-second-stage-of-labour-for-women-with-epidural-anaesthesia
#11
REVIEW
Marion Kibuka, Jim G Thornton
BACKGROUND: Epidural analgesia for pain relief in labour prolongs the second stage of labour and results in more instrumental deliveries. It has been suggested that a more upright position of the mother during all or part of the second stage may counteract these adverse effects. This is an update of a Cochrane review first published in 2013. OBJECTIVES: To assess the effects of different birthing positions (upright and recumbent) during the second stage of labour, on important maternal and fetal outcomes for women with epidural analgesia...
February 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28231605/endonasal-versus-external-dacryocystorhinostomy-for-nasolacrimal-duct-obstruction
#12
REVIEW
Lona Jawaheer, Caroline J MacEwen, Deepa Anijeet
BACKGROUND: A dacryocystorhinostomy (DCR) procedure aims to restore drainage of tears by bypassing a blockage in the nasolacrimal duct, through the creation of a bony ostium that allows communication between the lacrimal sac and the nasal cavity. It can be performed using endonasal or external approaches. The comparative success rates of these two approaches have not yet been established and this review aims to evaluate the relevant up-to-date research. OBJECTIVES: The primary aim of this review is to compare the success rates of endonasal DCR with that of external DCR...
February 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28231594/-conception-and-preliminary-evaluation-of-a-rehabilitation-attending-counseling-service-for-caregivers-of-stroke-patients
#13
J Jungbauer, T Krieger, M Floren
This paper presents the pilot project "The Caregivers' Guide", which is financed by the German Federal Ministry of Education and Research (BMBF). The project's concept is outreach-oriented and personal, giving constant support to relatives of stroke patients throughout rehabilitation. Its effects were reviewed in an accompanying study. A combination of qualitative and quantitative methods was chosen to gather data on the experiences and assessments of the caregivers, as well as changes during the counselling process...
February 23, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28231589/ultrasound-elastography-in-diffuse-and-focal-parotid-gland-lesions
#14
Naglaa Mansour, Benedikt Hofauer, Andreas Knopf
In Europe, ultrasound (US) is the diagnostic gold standard for the visualisation of parotid gland disorders. While high-resolution B-mode US reliably visualises focal lesions, its diagnostic capacity to distinguish tumour entities or to characterise diffuse lesions remains poor. Strain elastography (SE) and shear wave elastography (SWE) are novel imaging techniques that provide additional information about tissue elasticity. SE analyses the strain or displacement in response to force or compression and, therefore, shows the relative tissue elasticity within a selected region of interest (ROI)...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231588/checkpoint-inhibition-in-head-and-neck-cancer-immune-therapeutic-options-limitations-and-beyond
#15
Bastian Höchst, Percy A Knolle
The immune system functions to defend the organism against infectious microorganisms but also against transformed cells. This key role of the immune system, in particular cancer-specific T cells, in eliminating cancer cells is compromised by various immune escape strategies employed by cancer cells and the cancer microenvironment. Here, we review the current knowledge about the immune escape mechanisms of cancer and the attempts to reconstitute cancer-specific immunity by using checkpoint inhibitors in head and neck squamous cell carcinoma...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231584/characteristics-of-sarcoidosis-in-patients-with-previous-malignancy-causality-or-coincidence
#16
Nissim Arish, Rottem Kuint, Eli Sapir, Liran Levy, Avraham Abutbul, Zvi Fridlender, Uri Laxer, Neville Berkman
BACKGROUND: The association between sarcoidosis and malignancy is poorly defined. Sarcoidosis can precede, be diagnosed concurrently with, or follow malignancy. OBJECTIVES: We describe the clinical and radiological features of patients with sarcoidosis following malignancy to determine whether this association is causal or coincidental. METHODS: We performed a search for all patients with confirmed sarcoidosis following malignancy in our institution during 2001-2015...
February 24, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28231580/pediatric-hangman-s-fracture-a-comprehensive-review
#17
Michael Montalbano, Christian Fisahn, Marios Loukas, Rod J Oskouian, Jens R Chapman, R Shane Tubbs
PURPOSE: Over 170 years ago, traumatic spondylolisthesis of the axis or hangman's fracture was described. Most descriptions of this entity have focused on adult presentations. METHODS: We review the literature on pediatric cases of hangman's fracture emphasizing the embryological as well as presentation aspects. RESULTS: The majority of cervical spine fractures in children occur at C1 and C2 vertebrae. A normal anterolisthesis of C2 can be seen in younger children and can mimic the anterolisthesis seen after traumatic spondylolisthesis...
February 24, 2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28231579/vibration-induced-nystagmus-a-biomarker-for-vestibular-deficits-a-synopsis
#18
Karl-Friedrich Hamann
A review of more than 20 years of experience with vibratory stimulation in vestibular diseases is given. Vibrations in a frequency frame of 30-60 Hz are applied on the mastoid during 20 s. Eye movements are recorded by video-oculography to detect a vibration-induced nystagmus (VIN). A VIN occurs in cases of a side difference between the peripheral vestibular receptors beating to the side of better excitability. In patients with central lesions, a VIN does not appear generally, only exceptionally if the lesion is located laterally in the brain stem...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231576/molecular-markers-involved-in-tumorigenesis-of-thyroid-carcinoma-focus-on-aggressive-histotypes
#19
Gustavo C Penna, Fernanda Vaisman, Mario Vaisman, Manuel Sobrinho-Simões, Paula Soares
Thyroid cancer derived from follicular cells (TCDFC) comprises well-differentiated (papillary and follicular) carcinoma, poorly differentiated carcinoma, and anaplastic carcinoma. Papillary thyroid carcinoma is the most common endocrine cancer, and its incidence is steadily increasing. Lethality and aggressiveness of TCDFC is inversely correlated with differentiation degree. In this review, an emphasis has been put on molecular markers involved in tumorigenesis of thyroid carcinoma with a focus on aggressive histotypes and the role of such biomarkers in predicting thyroid cancer outcome...
February 24, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28231569/biomarkers-in-autoimmune-salivary-gland-disorders-a-review
#20
Benedikt Hofauer, Klaus Thuermel, Constanze Gahleitner, Andreas Knopf
Salivary glands are frequent sites of manifestations of autoimmune disorders in the head and neck. Sjögren syndrome, sarcoidosis, granulomatosis with polyangiitis, and IgG4-related sialadenitis represent the most important autoimmune salivary gland disorders. Due to the lack of specific symptoms, diagnosis of these conditions remains a challenge. Diagnosis is usually based on classification criteria involving clinical tests, histopathological evaluation, and serological examinations. Depending on the disease, biomarkers are of different value and have to be interpreted carefully...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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