Frederick A Heberle, Drew Marquardt, Milka Doktorova, Barbara Geier, Robert F Standaert, Peter Heftberger, Benjamin Kollmitzer, Jonathan D Nickels, Robert A Dick, Gerald W Feigenson, John Katsaras, Erwin London, Georg Pabst
Cell membranes possess a complex three-dimensional architecture, including nonrandom lipid lateral organization within the plane of a bilayer leaflet, and compositional asymmetry between the two leaflets. As a result, delineating the membrane structure-function relationship has been a highly challenging task. Even in simplified model systems, the interactions between bilayer leaflets are poorly understood, due in part to the difficulty of preparing asymmetric model membranes that are free from the effects of residual organic solvent or osmotic stress...
May 24, 2016: Langmuir: the ACS Journal of Surfaces and Colloids