Giorgia D'Este, Federico Fabris, Marco Stazi, Chiara Baggio, Morena Simonato, Aram Megighian, Michela Rigoni, Samuele Negro, Cesare Montecucco
Snake envenoming is a major, but neglected, tropical disease. Among venomous snakes, those inducing neurotoxicity such as kraits (Bungarus genus) cause a potentially lethal peripheral neuroparalysis with respiratory deficit in a large number of people each year. In order to prevent the development of a deadly respiratory paralysis, hospitalization with pulmonary ventilation and use of antivenoms are the primary therapies currently employed. However, hospitals are frequently out of reach for envenomated patients and there is a general consensus that additional, non-expensive treatments, deliverable even long after the snake bite, are needed...
January 8, 2024: PLoS Neglected Tropical Diseases