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https://www.readbyqxmd.com/read/28440394/g-protein-coupled-receptor-30-mediates-the-effects-of-estrogen-on-endothelial-cell-tube-formation-in%C3%A2-vitro
#1
Liyuan Zhou, Hong Chen, Xun Mao, Hongbo Qi, Philip N Baker, Hua Zhang
The placenta is the exchange organ between the mother and the fetus. The inadequate function of this organ is associated with a number of pregnancy disorders. Hypoxia and oxidative stress during placental development may induce endothelial dysfunction, resulting in the reduction in the perfusion of the placenta. During pregnancy, the levels of estrogen are increased. Decreased estrogen levels have been reported in women with preeclampsia. However, whether estrogen is involved in placental angiogenesis remains unclear...
April 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28382479/tuned-in-plant-roots-use-sound-to-locate-water
#2
Monica Gagliano, Mavra Grimonprez, Martial Depczynski, Michael Renton
Because water is essential to life, organisms have evolved a wide range of strategies to cope with water limitations, including actively searching for their preferred moisture levels to avoid dehydration. Plants use moisture gradients to direct their roots through the soil once a water source is detected, but how they first detect the source is unknown. We used the model plant Pisum sativum to investigate the mechanism by which roots sense and locate water. We found that roots were able to locate a water source by sensing the vibrations generated by water moving inside pipes, even in the absence of substrate moisture...
April 5, 2017: Oecologia
https://www.readbyqxmd.com/read/28371351/identification-of-pyrolysis-products-of-the-new-psychoactive-substance-2-amino-1-4-bromo-2-5-dimethoxyphenyl-ethanone-hydrochloride-bk-2c-b-and-its-iodo-analog-bk-2c-i
#3
Kelly B Texter, Rachel Waymach, Pierce V Kavanagh, John E O'Brien, Brian Talbot, Simon D Brandt, Elizabeth A Gardner
2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone hydrochloride (bk-2C-B) has recently emerged as a new psychoactive substance (NPS). It is most commonly consumed orally although there are indications that it might also be ingested by inhalation or 'smoking'. Information about the stability of bk-2C-B when exposed to heat is unavailable and the potential for pyrolytic degradation and formation of unknown substances available for inhalation prompted an investigation using a simulated 'meth pipe' scenario. Twelve products following pyrolysis of bk-2C-B were detected and verified by organic synthesis of the corresponding standards...
March 31, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28363920/design-and-rationale-of-a-matched-cohort-study-to-assess-the-effectiveness-of-a-combined-household-level-piped-water-and-sanitation-intervention-in-rural-odisha-india
#4
Heather Reese, Parimita Routray, Belen Torondel, Gloria Sclar, Maryann G Delea, Sheela S Sinharoy, Laura Zambrano, Bethany Caruso, Samir R Mishra, Howard H Chang, Thomas Clasen
INTRODUCTION: Government efforts to address massive shortfalls in rural water and sanitation in India have centred on construction of community water sources and toilets for selected households. However, deficiencies with water quality and quantity at the household level and community coverage and actual use of toilets have led Gram Vikas, a local non-governmental organization in Odisha, India, to develop an approach that provides household-level piped water connections contingent on full community-level toilet coverage...
March 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28353111/the-search-for-an-alternative-to-piped-water-and-sewer-systems-in-the-alaskan-arctic
#5
Korie A Hickel, Aaron Dotson, Timothy K Thomas, Mia Heavener, Jack Hébert, John A Warren
Forty-two communities in rural Alaska are considered unserved or underserved with water and sewer infrastructure. Many challenges exist to provide centralized piped water and sewer infrastructure to the homes, and they are exacerbated by decreasing capital funding. Unserved communities in rural Alaska experience higher rates of disease, supporting the recommendation that sanitation infrastructure should be provided. Organizations are pursuing alternative solutions to conventional piped water and sewer in order to maximize water use and reuse for public health...
March 29, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28336609/transition-from-turbulent-to-coherent-flows-in-confined-three-dimensional-active-fluids
#6
Kun-Ta Wu, Jean Bernard Hishamunda, Daniel T N Chen, Stephen J DeCamp, Ya-Wen Chang, Alberto Fernández-Nieves, Seth Fraden, Zvonimir Dogic
Transport of fluid through a pipe is essential for the operation of macroscale machines and microfluidic devices. Conventional fluids only flow in response to external pressure. We demonstrate that an active isotropic fluid, composed of microtubules and molecular motors, autonomously flows through meter-long three-dimensional channels. We establish control over the magnitude, velocity profile, and direction of the self-organized flows and correlate these to the structure of the extensile microtubule bundles...
March 24, 2017: Science
https://www.readbyqxmd.com/read/28298331/expression-of-leptin-receptor-in-the-oviduct-of-chinese-brown-frog-rana-dybowskii
#7
Liqin Xi, Yuning Liu, Zeqi Tang, Xia Sheng, Haolin Zhang, Qiang Weng, Meiyu Xu
The oviduct of Chinese brown frog (Rana dybowskii) expands specifically during pre-hibernation instead of in the breeding period. In this study, we investigated the expression of leptin receptor (Ob-Rb) in Rana dybowskii oviduct during the breeding period and pre-hibernation. Histologically, the oviduct of Rana dybowskii consists of glandular cells, tubule lumen and epithelial cells. The oviductal weight and pipe diameter also revealed significant differences, which were higher in pre-hibernation than that of the breeding period...
March 15, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28248977/evolution-of-protein-protein-interaction-networks-in-yeast
#8
Andrew Schoenrock, Daniel Burnside, Houman Moteshareie, Sylvain Pitre, Mohsen Hooshyar, James R Green, Ashkan Golshani, Frank Dehne, Alex Wong
Interest in the evolution of protein-protein and genetic interaction networks has been rising in recent years, but the lack of large-scale high quality comparative datasets has acted as a barrier. Here, we carried out a comparative analysis of computationally predicted protein-protein interaction (PPI) networks from five closely related yeast species. We used the Protein-protein Interaction Prediction Engine (PIPE), which uses a database of known interactions to make sequence-based PPI predictions, to generate high quality predicted interactomes...
2017: PloS One
https://www.readbyqxmd.com/read/28242223/evaluation-on-the-decomposability-of-tropical-forest-peat-soils-after-conversion-to-an-oil-palm-plantation
#9
Faustina E Sangok, Nagamitsu Maie, Lulie Melling, Akira Watanabe
To understand the variations in the decomposability of tropical peat soil following deforestation for an oil palm plantation, a field incubation experiment was conducted in Sarawak, Malaysia. Peat soils collected from three types of primary forest, namely Mixed Peat Swamp (MPS; Gonystylus-Dactylocladus-Neoscrotechinia association), Alan Batu (ABt; Shorea albida-Gonstylus-Strenonurus association), and Alan Bunga (ABg; Shorea albida association), were packed in polyvinyl chloride pipes and installed in an oil palm plantation...
February 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28238364/design-and-performance-of-subgrade-biogeochemical-reactors
#10
Jeff Gamlin, Doug Downey, Brad Shearer, Paul Favara
Subgrade biogeochemical reactors (SBGRs), also commonly referred to as in situ bioreactors, are a unique technology for treatment of contaminant source areas and groundwater plume hot spots. SBGRs have most commonly been configured for enhanced reductive dechlorination (ERD) applications for chlorinated solvent treatment. However, they have also been designed for other contaminant classes using alternative treatment media. The SBGR technology typically consists of removal of contaminated soil via excavation or large-diameter augers, and backfill of the soil void with gravel and treatment amendments tailored to the target contaminant(s)...
February 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28235877/spread-from-the-sink-to-the-patient-in-situ-study-using-green-fluorescent-protein-gfp-expressing-escherichia-coli-to-model-bacterial-dispersion-from-hand-washing-sink-trap-reservoirs
#11
Shireen Kotay, Weidong Chai, William Guilford, Katie Barry, Amy J Mathers
There have been an increasing number of reports implicating Gammaproteobacteria as often carrying genes of drug resistance from colonized sink traps to vulnerable hospitalized patients. However, the mechanism of transmission from the wastewater of the sink P-trap to patients remains poorly understood. Herein we report the use of a designated hand-washing sink lab gallery to model dispersion of green fluorescent protein (GFP)-expressing Escherichia coli from sink wastewater to the surrounding environment. We found no dispersion of GFP-expressing E...
April 15, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28228457/impact-of-workplace-physical-activity-interventions-on-physical-activity-and-cardiometabolic-health-among-working-age-women-a-systematic-review-and-meta-analysis
#12
Jennifer L Reed, Stephanie A Prince, Cara G Elliott, Kerri-Anne Mullen, Heather E Tulloch, Swapnil Hiremath, Lisa M Cotie, Andrew L Pipe, Robert D Reid
BACKGROUND: Cardiovascular disease is the leading cause of death among women in high-income Organization for Economic Co-operation and Development countries. Physical activity is protective for cardiovascular disease. The realities of modern life require working-age women to address work-related, family, and social demands. Few working-age women meet current moderate-to-vigorous-intensity physical activity (MVPA) recommendations. Given that working-age women spend a substantial proportion of their waking hours at work, places of employment may be an opportune and a controlled setting to implement programs, improving MVPA levels and enhancing cardiometabolic health...
February 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28153294/attenuated-total-reflectance-fourier-transform-infrared-spectroscopy-for-determination-of-long-chain-free-fatty-acid-concentration-in-oily-wastewater-using-the-double-wavenumber-extrapolation-technique
#13
Zisu Hao, Divya Malyala, Lisa Dean, Joel Ducoste
Long Chain Free Fatty Acids (LCFFAs) from the hydrolysis of fat, oil and grease (FOG) are major components in the formation of insoluble saponified solids known as FOG deposits that accumulate in sewer pipes and lead to sanitary sewer overflows (SSOs). A Double Wavenumber Extrapolative Technique (DWET) was developed to simultaneously measure LCFFAs and FOG concentrations in oily wastewater suspensions. This method is based on the analysis of the Attenuated Total Reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) spectrum, in which the absorbance of carboxyl bond (1710cm(-1)) and triglyceride bond (1745cm(-1)) were selected as the characteristic wavenumbers for total LCFFAs and FOG, respectively...
April 1, 2017: Talanta
https://www.readbyqxmd.com/read/28126285/particulate-matter-pollution-over-china-and-the-effects-of-control-policies
#14
REVIEW
Jiandong Wang, Bin Zhao, Shuxiao Wang, Fumo Yang, Jia Xing, Lidia Morawska, Aijun Ding, Markku Kulmala, Veli-Matti Kerminen, Joni Kujansuu, Zifa Wang, Dian Ding, Xiaoye Zhang, Huanbo Wang, Mi Tian, Tuukka Petäjä, Jingkun Jiang, Jiming Hao
China is one of the regions with highest PM2.5 concentration in the world. In this study, we review the spatio-temporal distribution of PM2.5 mass concentration and components in China and the effect of control measures on PM2.5 concentrations. Annual averaged PM2.5 concentrations in Central-Eastern China reached over 100μgm(-3), in some regions even over 150μgm(-3). In 2013, only 4.1% of the cities attained the annual average standard of 35μgm(-3). Aitken mode particles tend to dominate the total particle number concentration...
April 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28125625/on-the-identification-of-associations-between-five-world-health-organization-water-sanitation-and-hygiene-phenotypes-and-six-predictors-in-low-and-middle-income-countries
#15
Hugh Ellis, Erica Schoenberger
BACKGROUND: According to the most recent estimates, 842,000 deaths in low- to middle-income countries were attributable to inadequate water, sanitation and hygiene in 2012. Despite billions of dollars and decades of effort, we still lack a sound understanding of which kinds of WASH interventions are most effective in improving public health outcomes, and an important corollary-whether the right things are being measured. The World Health Organization (WHO) has made a concerted effort to compile comprehensive data on drinking water quality and sanitation in the developing world...
2017: PloS One
https://www.readbyqxmd.com/read/28117002/b3-adrenoceptor-control-of-lower-gen%C3%A4-tour%C3%A4-nary-tract-organs-and-funct%C3%A4-on-in-male-an-overv%C3%A4-ew
#16
Ecem Kaya, Suresh C Sikka, Didem Yilmaz Oral, Isil Ozakca, Serap Gur
BACKGROUND: The sympathetic nervous system is one component of the nervous regulatory system of the physiological function of the lower genitourinary tract. Our knowledge on the role of this sympathetic system has advanced during the last decade due to the characterization of b3-adrenoceptors (b3-ARs) in the urogenital system. OBJECTIVE: This review focuses on the pharmacological and molecular evidence supporting the functional roles of β3-AR in male genitourinary tissues of various species...
January 20, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28116058/effects-of-temperature-on-transcriptome-and-cuticular-hydrocarbon-expression-in-ecologically-differentiated-populations-of-desert-drosophila
#17
William J Etges, Cássia C de Oliveira, Subhash Rajpurohit, Allen G Gibbs
We assessed the effects of temperature differences on gene expression using whole-transcriptome microarrays and cuticular hydrocarbon variation in populations of cactophilic Drosophila mojavensis. Four populations from Baja California and mainland Mexico and Arizona were each reared on two different host cacti, reared to sexual maturity on laboratory media, and adults were exposed for 12 hr to 15, 25, or 35°C. Temperature differences influenced the expression of 3,294 genes, while population differences and host plants affected >2,400 each in adult flies...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28110150/enhanced-degradation-of-iopamidol-by-peroxymonosulfate-catalyzed-by-two-pipe-corrosion-products-cuo-and-%C3%AE-mno2
#18
Jun Hu, Huiyu Dong, Jiuhui Qu, Zhimin Qiang
Peroxymonosulfate (PMS) is a promising alternative for drinking water disinfection; also many organic micropollutants may be present in drinking water sources nowadays. However, pipe corrosion products (PCPs) may impact the reactions between a disinfectant and organic micropollutants in water distribution systems. This study investigated iopamidol (IPM) degradation by PMS under catalysis of two PCPs (i.e., CuO and δ-MnO2). The pseudo-first-order rate constant of IPM degradation in the CuO/PMS system (CuPS) was 3...
January 16, 2017: Water Research
https://www.readbyqxmd.com/read/28095993/evaluation-of-the-short-term-fate-and-transport-of-chemicals-of-emerging-concern-during-soil-aquifer-treatment-using-select-transformation-products-as-intrinsic-redox-sensitive-tracers
#19
Meriam Muntau, Manoj Schulz, Kevin S Jewell, Nina Hermes, Uwe Hübner, Thomas Ternes, Jörg E Drewes
In this study, known products from oxic transformation of the X-ray contrast medium iopromide were introduced for the first time as intrinsic tracer for in situ characterization of the transition zone between oxic and suboxic conditions during the initial phase of soil-aquifer treatment (SAT). Two wet-dry cycles of a full-scale infiltration basin were monitored to characterize hydraulic retention times, redox conditions, removal of bulk organic parameters and the fate of chemicals of emerging concern (CECs)...
January 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28078333/topography-guided-buckling-of-swollen-polymer-bilayer-films-into-three-dimensional-structures
#20
Joonwoo Jeong, Yigil Cho, Su Yeon Lee, Xingting Gong, Randall D Kamien, Shu Yang, A G Yodh
Thin films that exhibit spatially heterogeneous swelling often buckle into the third dimension to minimize stress. These effects, in turn, offer a promising strategy to fabricate complex three-dimensional structures from two-dimensional sheets. Here we employ surface topography as a new means to guide buckling of swollen polymer bilayer films and thereby control the morphology of resulting three-dimensional objects. Topographic patterns are created on poly(dimethylsiloxane) (PDMS) films selectively coated with a thin layer of non-swelling parylene on different sides of the patterned films...
February 7, 2017: Soft Matter
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