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Osteoarthritis, Knee

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https://www.readbyqxmd.com/read/28087567/interventions-to-increase-adherence-to-therapeutic-exercise-in-older-adults-with-low-back-pain-and-or-hip-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#1
Philippa J A Nicolson, Kim L Bennell, Fiona L Dobson, Ans Van Ginckel, Melanie A Holden, Rana S Hinman
OBJECTIVE: To evaluate whether interventions aimed at increasing adherence to therapeutic exercise increase adherence greater than a contextually equivalent control among older adults with chronic low back pain and/or hip/knee osteoarthritis. DESIGN: A systematic review and meta-analysis. DATA SOURCES: Five databases (MEDLINE (PubMed), CINAHL, SportDISCUS (EBSCO), Embase (Ovid) and Cochrane Library) were searched until 1 August 2016. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised controlled trials that isolated the effects of interventions aiming to improve adherence to therapeutic exercise among adults ≥45 years of age with chronic low back pain and/or hip/knee osteoarthritis were included...
January 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28087557/a-longitudinal-comparative-study-of-falls-in-persons-with-knee-arthroplasty-and-persons-with-or-at-high-risk-for-knee-osteoarthritis
#2
Daniel L Riddle, Gregory J Golladay
No abstract text is available yet for this article.
January 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28087412/pain-prediction-by-serum-biomarkers-of-bone-turnover-in-people-with-knee-osteoarthritis-an-observational-study-of-tracp5b-and-cathepsin-k-in-oa
#3
Lilian N Nwosu, Maximilian Allen, Laura Wyatt, Janet L Huebner, Victoria Chapman, David A Walsh, Virginia B Kraus
OBJECTIVES: To investigate serum biomarkers, tartrate resistant acid phosphatase 5b (TRAcP5b) and cathepsin K, indicative of osteoclastic bone resorption, and their relationship to pain and pain change in knee osteoarthritis (OA). METHODS: Sera and clinical data were collected from 129 people (97 with 3-year follow-up) with knee OA from the Prediction of Osteoarthritis Progression (POP) cohort. Knee OA-related outcomes in POP included: WOMAC pain, NHANES I (pain, aching and stiffness), subchondral sclerosis, and radiographically determined tibiofemoral and patellofemoral OA...
January 10, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28087396/influence-of-coronal-bowing-on-the-lower-alignment-and-the-positioning-of-component-in-navigation-and-conventional-total-knee-arthroplasty
#4
Hideo Kobayashi, Yasushi Akamatsu, Ken Kumagai, Yoshihiro Kusayama, Masato Aratake, Tomoyuki Saito
BACKGROUND: Coronal alignment is an important factor for the function and longevity of total knee arthroplasty (TKA). Coronal bowing of the lower extremity is common among Asians and it may pose a risk for malalignment of the lower leg and malposition of component. HYPOTHESIS: We hypothesized that coronal bowing itself has a risk for malalignment of the lower leg and malposition of femoral / tibial components and that navigation TKA is beneficial for patients with coronal bowing...
January 10, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28079634/characteristics-of-patients-with-satisfactory-functional-gain-following-total-joint-arthroplasty-in-a-postacute-rehabilitation-setting
#5
Avital Hershkovitz, Marina Vesilkov, Yichayaou Beloosesky, Shai Brill
BACKGROUND AND PURPOSE: Total joint arthroplasty (TJA) is an effective and successful treatment of osteoarthritis of the hip and knee as quantified by several measures, such as pain relief, improved walking, improved self-care, functions, and increased quality of life. Data are lacking as to the definition of a satisfactory functional gain in a postacute setting and identifying the characteristics of older patients with TJA who may achieve that gain. Our aim was to characterize patients who may achieve a satisfactory functional gain in a postacute rehabilitation setting following TJA...
January 10, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28078503/efficacy-of-pulsed-nd-yag-laser-in-the-treatment-of-patients-with-knee-osteoarthritis-a-randomized-controlled-trial
#6
Mohamed Salaheldien Mohamed Alayat, Tarek Helmy Ahmed Aly, Aly Elsayed Mohamed Elsayed, Ammar Suliman Mohamed Fadil
The purpose of this study was to investigate the effects of pulsed Nd:YAG laser plus glucosamine/chondroitin sulfate (GCS) in patients with knee osteoarthritis (KOA) by examining changes in pain and knee function, as well as synovial thickness (ST) and femoral cartilage thickness (FCT). Sixty-seven male patients participated, with a mean (SD) age of 53.85 (4.39) years, weight of 84.01 (4.70) kg, height of 171.51 (3.96) cm, and BMI of 28.56 (1.22). Group 1 was treated with high-intensity laser therapy (HILT), GCS, and exercises (HILT + GCS + EX)...
January 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28078435/the-effects-of-therapeutic-exercises-on-pain-muscle-strength-functional-capacity-balance-and-hemodynamic-parameters-in-knee-osteoarthritis-patients-a-randomized-controlled-study-of-supervised-versus-home-exercises
#7
Tuğba Kuru Çolak, Bahar Kavlak, Onur Aydoğdu, Emir Şahin, Gönül Acar, İlkşan Demirbüken, Zübeyir Sarı, İlker Çolak, Güven Bulut, M Gülden Polat
The aim of the study was to compare the effects of low-intensity exercise programs for lower extremities, either supervised or at home, on pain, muscle strength, balance and the hemodynamic parameters of knee osteoarthritis (OA) patients. This randomized study included 78 patients with knee OA in 2 groups of supervised and home-based exercise program. Exercises were applied to the first group in the clinic as a group exercise program and were demonstrated to the second group to be performed at home. Before and after the 6-week exercise program, assessment was made of pain, quadriceps and hamstring muscle strengths, 6-min walk test (6MWT), and non-invasive hemodynamic parameters...
January 11, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28077355/no-evidence-for-the-use-of-stem-cell-therapy-for-tendon-disorders-a-systematic-review
#8
Haiko I M F L Pas, Maarten H Moen, Hidde J Haisma, Marinus Winters
INTRODUCTION: Stem cells have emerged as a new treatment option for tendon disorders. We systematically reviewed the current evidence for stem cell therapy in tendon disorders. METHODS: Randomised and non-randomised controlled trials, cohort studies and case series with a minimum of 5 cases were searched in MEDLINE, CENTRAL, EMBASE, CINAHL, PEDro and SPORTDiscus. In addition, we searched grey literature databases and trial registers. Only human studies were included and no time or language restrictions were applied to our search...
January 11, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28077008/is-decreasing-mortality-in-total-hip-and-knee-arthroplasty-patients-dependent-on-patients-comorbidity
#9
Eva N Glassou, Alma B Pedersen, Torben B Hansen
Background and purpose - Mortality after primary total hip and knee arthroplasty (THA and TKA) has declined, and the proportion of THA and TKA patients with comorbid conditions has increased. We therefore wanted to examine changes in comorbidity burden over time and the impact of comorbid on mortality following primary total hip and knee arthroplasty in patients with osteoarthritis. Patients and methods - We used the Danish arthroplasty registers to identify THA and TKA patients from 1996 through 2013. From administrative databases, we collected data on pre-surgery hospital history for all patients, which were used to calculate the Charlson comorbidity index (CCI)...
January 12, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28073368/advanced-knee-structure-analysis-aksa-a-comparison-of-bone-mineral-density-and-trabecular-texture-measurements-using-computed-tomography-and-high-resolution-peripheral-quantitative-computed-tomography-of-human-knee-cadavers
#10
Torsten Lowitz, Oleg Museyko, Valérie Bousson, Christine Chappard, Liess Laouisset, Jean-Denis Laredo, Klaus Engelke
BACKGROUND: A change of loading conditions in the knee causes changes in the subchondral bone and may be a cause of osteoarthritis (OA). However, quantification of trabecular architecture in vivo is difficult due to the limiting spatial resolution of the imaging equipment; one approach is the use of texture parameters. In previous studies, we have used digital models to simulate changes of subchondral bone architecture under OA progression. One major result was that, using computed tomography (CT) images, subchondral bone mineral density (BMD) in combination with anisotropy and global homogeneity could characterize this progression...
January 10, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28072902/development-of-an-encompassing-questionnaire-for-evaluating-the-outcomes-following-total-knee-arthroplasty
#11
Morad Chughtai, Anton Khlopas, Melbin Thomas, Chukwuweike U Gwam, Julio J Jauregui, Randa K Elmallah, Martin Roche, Michael A Mont
INTRODUCTION: There are many standardized scales and questionnaires used to evaluate TKA patients; however, individually they do not always assess patients adequately. Consequently, many are used in combinations to provide a thorough evaluation. However, this leads to redundancy, confusion, and an excessive patient time-burden. Therefore, the purpose of this study was to develop a usable combined knee questionnaire that combines questions in a non-redundant manner. Specifically, we aimed to: 1) create a combined knee questionnaire that encompasses questions from multiple systems, while eliminating redundancy; 2) correlate the new system with the existing validated questionnaires; and 3) determine the length of time it takes to administer this new questionnaire...
10, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28072630/bracing-of-the-reconstructed-and-osteoarthritic-knee-during-high-dynamic-load-tasks
#12
Harvi F Hart, Kay M Crossley, Natalie J Collins, David C Ackland
PURPOSE: Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics are frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee brace during high dynamic loading activities in individuals with lateral knee osteoarthritis after ACLR and valgus malalignment. METHODS: Nineteen participants who had undergone ACLR 5 to 20 years previously and had symptomatic and radiographic lateral knee osteoarthritis with valgus malalignment were assessed...
January 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28070864/factors-that-affect-the-content-of-cadmium-nickel-copper-and-zinc-in-tissues-of-the-knee-joint
#13
Wojciech Roczniak, Barbara Brodziak-Dopierała, Elżbieta Cipora, Agata Jakóbik-Kolon, Joanna Kluczka, Magdalena Babuśka-Roczniak
Osteoarthritis causes the degradation of the articular cartilage and periarticular bones. Trace elements influence the growth, development and condition of the bone tissue. Changes to the mineral composition of the bone tissue can cause degenerative changes and fractures. The aim of the research was to determine the content of cadmium (Cd), nickel (Ni), copper (Cu) and zinc (Zn) in the tibia, the femur and the meniscus in men and women who underwent a knee replacement surgery. Samples were collected from 50 patients, including 36 women and 14 men...
January 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28070457/the-concurrent-validity-and-reliability-of-the-leg-motion-system-for-measuring-ankle-dorsiflexion-range-of-motion-in-older-adults
#14
Carlos Romero Morales, César Calvo Lobo, David Rodríguez Sanz, Irene Sanz Corbalán, Beatriz Ruiz Ruiz, Daniel López López
BACKGROUND: New reliable devices for range of motion (ROM) measures in older adults are necessary to improve knowledge about the functional capability in this population. Dorsiflexion ROM limitation is associated with ankle injuries, foot pain, lower limb disorders, loss of balance, gait control disorders and fall risk in older adults. The aim of the present study was to assess the validity and reliability of the Leg Motion device for measuring ankle dorsiflexion ROM in older adults. METHODS: Adescriptive repeated-measures study was designed to test the reliability of Leg Motion in thirty-three healthy elderly patients older than 65 years...
2017: PeerJ
https://www.readbyqxmd.com/read/28068837/immediate-effects-of-acupuncture-treatment-on-intra-and-inter-limb-contributions-to-body-support-during-gait-in-patients-with-bilateral-medial-knee-osteoarthritis
#15
Yen-Hung Liu, I-Pin Wei, Ting-Ming Wang, Tung-Wu Lu, Jaung-Geng Lin
Knee osteoarthritis (OA) often leads to altered balance control, joint motion and loading patterns during gait. Acupuncture has been proven to be effective in pain relief but its effects on inter-joint load-sharing for body balance have not been reported. The current study bridged the gap by quantifying the immediate effects of acupuncture on the inter-joint and inter-limb load-sharing in patients with knee OA during level walking in terms of the total support moment (Ms) and the contribution of individual joints to the total support moment...
January 9, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28068520/impact-loading-following-quadriceps-strength-training-in-individuals-with-medial-knee-osteoarthritis-and-varus-alignment
#16
Crystal O Kean, Rana S Hinman, Tim V Wrigley, Boon-Whatt Lim, Kim L Bennell
BACKGROUND: Greater impact loading at initial contact is postulated to play a role in the progression of osteoarthritis. Quadriceps weakness is common in individuals with knee osteoarthritis and may contribute to high impact loading. The purpose of this study was to examine the effects of quadriceps strengthening on impact loading parameters. METHODS: Data from 97 individuals with knee osteoarthritis who participated in a randomized clinical trial examining effects of a 12-week quadriceps strengthening program was used to conduct this secondary exploratory analysis...
January 4, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28068480/magnetic-resonance-imaging-characterization-and-clinical-outcomes-after-neocart-surgical-therapy-as-a-primary-reparative-treatment-for-knee-cartilage-injuries
#17
Devon E Anderson, Riley J Williams, Thomas M DeBerardino, Dean C Taylor, C Benjamin Ma, Marie S Kane, Dennis C Crawford
BACKGROUND: Autologous cartilage tissue implants, including the NeoCart implant, are intended to repair focal articular cartilage lesions. Short-term results from United States Food and Drug Administration (FDA) phase I and phase II clinical trials indicated that the NeoCart implant was safe when surgically applied as a cell-based therapy and efficacious compared with microfracture. HYPOTHESIS: Quantitative magnetic resonance imaging (MRI) analysis would reveal NeoCart tissue maturation through to 60-month follow-up...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28065624/outcome-of-unicondylar-knee-arthroplasty-vs-total-knee-arthroplasty-for-early-medial-compartment-arthritis-a-randomized-study
#18
Vikas Kulshrestha, Barun Datta, Santhosh Kumar, Gaurav Mittal
BACKGROUND: With increasing number of patients with early osteoarthritis of knee opting for total knee arthroplasty (TKA), there has been increase in patients dissatisfied with surgical outcomes. It is being presumed that offering unicondylar knee arthroplasty (UKA) to them would improve outcomes. METHODS: Primary objective of our study was to look for any difference in patient-reported outcome and function at 2-year follow-up in patients undergoing UKA as compared to TKA...
December 23, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28065381/the-contribution-of-3d-quantitative-meniscal-and-cartilage-measures-to-variation-in-normal-radiographic-joint-space-width-data-from-the-osteoarthritis-initiative-healthy-reference-cohort
#19
Melanie Roth, Wolfgang Wirth, Katja Emmanuel, Adam G Culvenor, Felix Eckstein
OBJECTIVE: To explore to what extent three-dimensional measures of the meniscus and femorotibial cartilage explain the variation in medial and lateral femorotibial radiographic joint space width (JSW), in healthy men and women. METHODS: The right knees of 87 Osteoarthritis Initiative healthy reference participants (no symptoms, radiographic signs or risk factors of osteoarthritis; 37 men, 50 women; age 55.0±7.6; BMI 24.4±3.1) were assessed. Quantitative measures of subregional femorotibial cartilage thickness and meniscal position and morphology were computed from segmented magnetic resonance images...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28065216/expression-of-mirna-140-in-chondrocytes-and-synovial-fluid-of-knee-joints-in-patients-with-osteoarthritis
#20
Si Hai-Bo, Zeng Yi, Zhou Zong-Ke, Pei Fu-Xing, Lu Yan-Rong, Cheng Jing-Qiu, Shen Bin
Objective To investigate the expression of miRNA-140 in chondrocytes and synovial fluid of osteoarthritis (OA) patients, and explore the relationship between the miRNA-140 expression and OA severity.Methods This study enrolled 30 OA patients who underwent total knee arthroplasty for chondrocytes sampling and 30 OA patients who underwent intra-articular injection for synovial fluid sampling. All OA patients were grouped into mild [Kellgren and Lawrence (KL) grade 1-2], moderate (KL grade 3) and severe (KL grade 4), with 10 in each subgroups for each sampling purposes...
November 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
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