keyword
MENU ▼
Read by QxMD icon Read
search

Putamen

keyword
https://www.readbyqxmd.com/read/28718512/overweight-is-associated-with-lower-resting-state-functional-connectivity-in-females-after-eliminating-genetic-effects-a-twin-study
#1
Stieneke Doornweerd, Eelco van Duinkerken, Eco J de Geus, Parniane Arbab-Zadeh, Dick J Veltman, Richard G IJzerman
Obesity is related to altered functional connectivity of resting state brain networks that are involved in reward and motivation. It is unknown to what extent these associations reflect genetic confounding and whether the obesity-related connectivity changes are associated with differences in dietary intake. In this study, resting state functional MRI was performed after an overnight fast in 16 female monozygotic twin pairs (aged 48.8 ± 9.8 years) with a mean BMI discordance of 3.96 ± 2.1 kg/m(2) (range 0...
July 17, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28713979/roles-of-electro-acupuncture-in-glucose-metabolism-as-assessed-by-18f-fdg-pet-imaging-and-ampk%C3%AE-phosphorylation-in-rats-with-ischemic-stroke
#2
Jingsong Wu, Bingbing Lin, Weilin Liu, Jia Huang, Guanhao Shang, Yunjiao Lin, Lulu Wang, Lidian Chen, Jing Tao
Targeted energy metabolism balance contributes to neural survival during ischemic stroke. Herein, we tested the hypothesis that electro‑acupuncture (EA) can enhance cerebral glucose metabolism assessed by 18F‑fluorodeoxyglucose/positron emission tomography (18F‑FDG/PET) imaging to prevent propagation of tissue damage and improve neurological outcome in rats subjected to ischemia and reperfusion injury. Rats underwent middle cerebral artery occlusion (MCAO) and received EA treatment at the LI11 and ST36 acupoints or non‑acupoint treatment once a day for 7 days...
July 6, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28712121/motor-symptom-laterality-affects-acquisition-in-parkinson-s-disease-a-cognitive-and-functional-magnetic-resonance-imaging-study
#3
Pei Huang, Yu-Yan Tan, Dong-Qiang Liu, Mohammad M Herzallah, Elizabeth Lapidow, Ying Wang, Yu-Feng Zang, Mark A Gluck, Sheng-Di Chen
BACKGROUND AND OBJECTIVES: Asymmetric onset of motor symptoms in PD can affect cognitive function. We examined whether motor-symptom laterality could affect feedback-based associative learning and explored its underlying neural mechanism by functional magnetic resonance imaging in PD patients. METHODS: We recruited 63 early-stage medication-naïve PD patients (29 left-onset medication-naïve patients, 34 right-onset medication-naïve patients) and 38 matched normal controls...
July 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28707138/gray-matter-changes-and-cognitive-predictors-of-2-year-follow-up-abnormalities-in-early-onset-first-episode-psychosis
#4
Josefina Castro-Fornieles, Nuria Bargalló, Anna Calvo, Celso Arango, Immaculada Baeza, Ana Gonzalez-Pinto, Mara Parellada, Montserrat Graell, Carmen Moreno, Soraya Otero, Joost Janssen, Marta Rapado-Castro, Elena de la Serna
This study aims to examine regional gray matter (GM) changes over a period of 2 years in patients diagnosed with early-onset first-episode psychosis (EO-FEP), and to identify baseline predictors of abnormalities at the follow-up. Fifty-nine patients with EO-FEP aged 11-17 years were assessed. Magnetic resonance imaging was carried out at admission and 2 years later. Changes over time were assessed with voxel-based morphometry. Fifty-nine patients (34 schizophrenia-SCZ, 15 bipolar disorder-BP, and 10 other psychotic disorders) and 70 healthy controls were assessed...
July 13, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28707072/catechol-o-methyltransferase-val158met-polymorphism-on-striatum-structural-covariance-networks-in-alzheimer-s-disease
#5
Chiung-Chih Chang, Shih-Jen Tsai, Nai-Ching Chen, Chi-Wei Huang, Shih-Wei Hsu, Ya-Ting Chang, Mu-En Liu, Wen-Neng Chang, Wan-Chen Tsai, Chen-Chang Lee
The catechol-O-methyltransferase enzyme metabolizes dopamine in the prefrontal axis, and its genetic polymorphism (rs4680; Val158Met) is a known determinant of dopamine signaling. In this study, we investigated the possible structural covariance networks that may be modulated by this functional polymorphism in patients with Alzheimer's disease. Structural covariance networks were constructed by 3D T1 magnetic resonance imaging. The patients were divided into two groups: Met-carriers (n = 91) and Val-homozygotes (n = 101)...
July 13, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28705766/patients-with-major-depressive-disorder-exhibit-reduced-reward-size-coding-in-the-striatum
#6
Masahiro Takamura, Yasumasa Okamoto, Go Okada, Shigeru Toki, Tetsuya Yamamoto, Naho Ichikawa, Asako Mori, Hideaki Minagawa, Yoshiyuki Takaishi, Yasutaka Fujii, Yoko Kaichi, Yuji Akiyama, Kazuo Awai, Shigeto Yamawaki
BACKGROUND: Anhedonia is a core symptom of major depressive disorder (MDD). While recent evidence suggests that reduced motivation for reward may be a core feature of anhedonia, the abnormalities in modulatory neural responses to variable reward amounts in MDD patients remain unclear. We investigated whether MDD patients' ability to represent variable-sized monetary rewards in the striatum is disrupted. METHODS: Twelve MDD patients and 12 healthy volunteers completed an assessment of psychometric status and participated in a functional magnetic resonance imaging (fMRI) task that involved the anticipation of financial reward (monetary incentive delay task)...
July 10, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28700568/neonatal-basal-ganglia-and-thalamic-volumes-very-preterm-birth-and-7-year-neurodevelopmental-outcomes
#7
Wai Yen Loh, Peter J Anderson, Jeanie L Y Cheong, Alicia J Spittle, Jian Chen, Katherine J Lee, Charlotte Molesworth, Terrie E Inder, A Connelly, Lex W Doyle, Deanne K Thompson
BACKGROUND: This study aims to (1) compare volumes of individual basal ganglia nuclei (caudate nucleus, pallidum, putamen) and the thalamus between very preterm (VP) and term-born infants at term-equivalent age; (2) explore neonatal basal ganglia and thalamic volume relationships with 7-year neurodevelopmental outcomes, and whether these relationships differed between VP and term-born children. METHODS: 210 VP (<30 weeks' gestational age) and 39 term-born (≥37 weeks' gestational age) infants underwent brain magnetic resonance imaging at term-equivalent age, and deep grey matter volumes of interest were automatically generated...
July 12, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28699182/amygdala-and-hippocampus-volumes-are-differently-affected-by-childhood-trauma-in-patients-with-bipolar-disorders-and-healthy-controls
#8
Delfina Janiri, Gabriele Sani, Pietro De Rossi, Fabrizio Piras, Mariangela Iorio, Nerisa Banaj, Giulia Giuseppin, Edoardo Spinazzola, Matteo Maggiora, Elisa Ambrosi, Alessio Simonetti, Gianfranco Spalletta
OBJECTIVES: Volumetric studies on deep gray matter structures in bipolar disorder (BP) have reported contrasting results. Childhood trauma, a relevant environmental stressor for BP, could account for the variability of the results, modulating differences in the amygdala and hippocampus in patients with BP compared with healthy controls (HC). Our study aimed to test this hypothesis. METHODS: We assessed 105 outpatients, diagnosed with bipolar disorder type I (BP-I) or bipolar disorder type II (BP-II) according to DSM-IV-TR criteria, and 113 HC subjects...
July 12, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28697581/altered-gray-matter-volume-and-functional-connectivity-of-the-motor-network-in%C3%A2-young%C3%A2-divers
#9
Xia Liu, Liansheng Liu, Fen Hou, Zhifeng Zhou, Qingying Wu, Hengguo Li
BACKGROUND: Motor learning and professional sports training can induce plastic changes in brain structures that are associated with distinct training demands. OBJECTIVE: To testify the hypothesis of that regional gray matter structures in the motor-related cortex and its functional connectivity (FC) are altered in young divers. METHODS: We undertook T1-voxel-based morphometry (VBM) structural and resting-state functional magnetic resonance imaging in groups of diving athletes (DAs) and demographically-matched healthy controls...
July 7, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28694044/more-randomized-and-resilient-in-the-topological-properties-of-functional-brain-networks-in-patients-with-major-depressive-disorder
#10
Huaizhou Li, Haiyan Zhou, Yang Yang, Haiyuan Wang, Ning Zhong
Previous studies have reported the enhanced randomization of functional brain networks in patients with major depressive disorder (MDD). However, little is known about the changes of key nodal attributes for randomization, the resilience of network, and the clinical significance of the alterations. In this study, we collected the resting-state functional MRI data from 19 MDD patients and 19 healthy control (HC) individuals. Graph theory analysis showed that decreases were found in the small-worldness, clustering coefficient, local efficiency, and characteristic path length (i...
July 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28694016/-18-f-fdopa-positron-emission-tomography-in-manganese-exposed-workers
#11
Susan R Criswell, Susan Searles Nielsen, Mark Warden, Joel S Perlmutter, Stephen M Moerlein, Hubert P Flores, John Huang, Lianne Sheppard, Noah Seixas, Harvey Checkoway, Brad A Racette
Occupational manganese (Mn) exposure is associated with the development of parkinsonism; however, the mechanism of neurotoxicity is unknown. Brain positron emission tomography (PET) imaging provides a non-invasive method of assessing dopamineric neuronal function. 6-[(18)F]fluoro-L-DOPA (FDOPA) PET reflects in-vivo nigrostriatal function, but results in Mn exposure are conflicting. The objective of this study was to investigate the association between Mn exposure secondary to occupational welding, FDOPA striatal uptake, and clinical parkinsonism as measured by Unified Parkinson Disease Rating Scale motor subscore 3 (UPDRS3) scores...
July 7, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28693073/-resting-state-fmri-study-of-emotional-network-in-patients-with-postconcussion-syndrome
#12
X Zhang, R B Qian, X M Fu, B Lin, D Zhang, C S Xia, X P Wei, C S Niu, Y H Wang
Objective: To discuss functional connectivity changes in the emotional network of patients with post-concussion syndrome (PCS) and their clinical significance by resting-state functional magnetic resonance imaging (rs-fMRI). Methods: Twenty-seven patients with PCS were recruited from the Department of Neurosurgery of Anhui provincial hospital affiliated to Anhui medical university from October 2015 to April 2016, and 27 healthy subjects were recruited as the controls. The Hamilton Anxiety Scale (HAMA) and The Hamilton Depression Scale (HAMD) were used to evaluate the emotional state of two groups of subjects...
July 4, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28691842/response-in-taste-circuitry-is-not-modulated-by-hunger-and-satiety-in-women-remitted-from-bulimia-nervosa
#13
Alice V Ely, Christina E Wierenga, Amanda Bischoff-Grethe, Ursula F Bailer, Laura A Berner, Julie L Fudge, Martin P Paulus, Walter H Kaye
Individuals with bulimia nervosa (BN) engage in episodes of binge eating, marked by loss of control and eating despite fullness. Does altered reward and metabolic state contribute to BN pathophysiology? Normally, hunger increases (and satiety decreases) reward salience to regulate eating. We investigated whether BN is associated with an abnormal response in a neural circuit involved in translating taste signals into motivated behavior, when hungry and fed. Twenty-six women remitted from BN (RBN) and 22 control women (CW) were administered water and sucrose during 2 counterbalanced fMRI visits, following a 16-hr fast or a standardized breakfast...
July 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28691248/adolescent-alcohol-exposure-decreases-frontostriatal-resting-state-functional-connectivity-in-adulthood
#14
Margaret A Broadwater, Sung-Ho Lee, Yang Yu, Hongtu Zhu, Fulton T Crews, Donita L Robinson, Yen-Yu Ian Shih
Connectivity of the prefrontal cortex (PFC) matures through adolescence, coinciding with emergence of adult executive function and top-down inhibitory control over behavior. Alcohol exposure during this critical period of brain maturation may affect development of PFC and frontolimbic connectivity. Adult rats exposed to adolescent intermittent ethanol (AIE; 5 g/kg ethanol, 25 percent v/v in water, intragastrically, 2-day-on, 2-day-off, postnatal day 25-54) or water control underwent resting-state functional MRI to test the hypothesis that AIE induces persistent changes in frontolimbic functional connectivity under baseline and acute alcohol conditions (2 g/kg ethanol or saline, intraperitoneally administered during scanning)...
July 9, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28689259/differential-diagnosis-of-parkinsonism-by-a-combined-use-of-diffusion-kurtosis-imaging-and-quantitative-susceptibility-mapping
#15
Kenji Ito, Chigumi Ohtsuka, Kunihiro Yoshioka, Hiroyuki Kameda, Suguru Yokosawa, Ryota Sato, Yasuo Terayama, Makoto Sasaki
PURPOSE: We investigated whether diffusion kurtosis imaging (DKI) and quantitative susceptibility mapping (QSM) could detect pathological changes that occur in Parkinson's disease (PD), multiple system atrophy with predominant parkinsonism (MSA-P) or predominant cerebellar ataxia (MSA-C), and progressive supranuclear palsy syndrome (PSPS) and thus be used for differential diagnosis that is often difficult. METHODS: Seventy patients (41 with PD, 6 with MSA-P, 7 with MSA-C, 16 with PSPS) and 20 healthy controls were examined using a 3...
July 8, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28684245/assessment-of-neuroinflammation-in-patients-with-idiopathic-rapid-eye-movement-sleep-behaviour-disorder-a-case-control-study
#16
Morten Gersel Stokholm, Alex Iranzo, Karen Østergaard, Mónica Serradell, Marit Otto, Kristina Bacher Svendsen, Alicia Garrido, Dolores Vilas, Per Borghammer, Joan Santamaria, Arne Møller, Carles Gaig, David J Brooks, Eduardo Tolosa, Nicola Pavese
BACKGROUND: Findings from longitudinal follow-up studies in patients with idiopathic rapid-eye-movement sleep behaviour disorder (IRBD) have shown that most patients will eventually develop the synucleinopathies Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy. Neuroinflammation in the form of microglial activation is present in synucleinopathies and is a potential therapeutic target to halt or delay the neurodegenerative process. We aimed to investigate whether neuroinflammation is present in patients with IRBD and its possible relation to nigrostriatal dopamine function...
July 3, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28683981/noradrenergic-modulation-of-neural-erotic-stimulus-perception
#17
Heiko Graf, Maike Wiegers, Coraline Danielle Metzger, Martin Walter, Georg Grön, Birgit Abler
We recently investigated neuromodulatory effects of the noradrenergic agent reboxetine and the dopamine receptor affine amisulpride in healthy subjects on dynamic erotic stimulus processing. Whereas amisulpride left sexual functions and neural activations unimpaired, we observed detrimental activations under reboxetine within the caudate nucleus corresponding to motivational components of sexual behavior. However, broadly impaired subjective sexual functioning under reboxetine suggested effects on further neural components...
July 3, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28680706/abnormal-functional-connectivity-of-ventral-anterior-insula-in-asthmatic-patients-with-depression
#18
Yuqun Zhang, Yuan Yang, Rongrong Bian, Yingying Yin, Zhenghua Hou, Yingying Yue, Zhi Xu, Yonggui Yuan
OBJECTIVE: To explore the underlying mechanism of depression in asthmatic patients, the ReHo in the insula and its FC was used to probe the differences between depressed asthmatic (DA) and nondepressed asthmatic (NDA) patients. METHODS: 18 DA patients, 24 NDA patients, and 60 healthy controls (HCs) received resting-state fMRI scan, severity of depression, and asthma control assessment. RESULTS: DA patients showed increased FC between the left ventral anterior insula (vAI) and the left middle temporal gyrus compared with both NDA and HC groups...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28676738/the-multiple-correspondence-analysis-method-and-brain-functional-connectivity-its-application-to-the-study-of-the-non-linear-relationships-of-motor-cortex-and-basal-ganglia
#19
Clara Rodriguez-Sabate, Ingrid Morales, Alberto Sanchez, Manuel Rodriguez
The complexity of basal ganglia (BG) interactions is often condensed into simple models mainly based on animal data and that present BG in closed-loop cortico-subcortical circuits of excitatory/inhibitory pathways which analyze the incoming cortical data and return the processed information to the cortex. This study was aimed at identifying functional relationships in the BG motor-loop of 24 healthy-subjects who provided written, informed consent and whose BOLD-activity was recorded by MRI methods. The analysis of the functional interaction between these centers by correlation techniques and multiple linear regression showed non-linear relationships which cannot be suitably addressed with these methods...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28675473/localization-of-orofacial-representation-in-the-corona-radiata-internal-capsule-and-cerebral-peduncle-in-macaca-mulatta
#20
R J Morecraft, A Binneboese, K S Stilwell-Morecraft, J Ge
Subcortical white matter injury is often accompanied by orofacial motor dysfunction, but little is known about the structural substrates accounting for these common neurological deficits. We studied the trajectory of the corticobulbar projection from the orofacial region of the primary (M1), ventrolateral (LPMCv), supplementary (M2), rostral cingulate (M3) and caudal cingulate (M4) motor regions through the corona radiata (CR), internal capsule (IC) and crus cerebri of the cerebral peduncle (ccCP). In the CR each pathway was segregated...
July 4, 2017: Journal of Comparative Neurology
keyword
keyword
20850
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"