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https://www.readbyqxmd.com/read/29223110/systemic-inflammatory-markers-associated-with-cardiovascular-disease-and-acute-and-chronic-exposure-to-fine-particulate-matter-air-pollution-pm2-5-among-us-nhanes-adults-with-metabolic-syndrome
#1
Arvind Dabass, Evelyn O Talbott, Judith R Rager, Gary M Marsh, Arvind Venkat, Fernando Holguin, Ravi K Sharma
BACKGROUND: There has been no investigation to date of adults with metabolic syndrome examining the association of short and long-term exposure to fine particulate matter (PM2.5) air pollution with cardiovascular-disease related inflammatory marker (WBC and CRP) levels in a nationally representative sample. The goal of this study is to assess the susceptibility of adults with metabolic syndrome to PM2.5 exposure as suggested by increased cardiovascular-disease related inflammatory marker levels...
December 6, 2017: Environmental Research
https://www.readbyqxmd.com/read/29223087/oxidative-stress-in-birds-along-a-nox-and-urbanisation-gradient-an-interspecific-approach
#2
Pablo Salmón, Emilie Stroh, Amparo Herrera-Dueñas, Maria von Post, Caroline Isaksson
Urbanisation is regarded as one of the most threatening global issues for wildlife, however, measuring its impact is not always straight forward. Oxidative stress physiology has been suggested to be a useful biomarker of health and therefore, a potentially important indicator of the impact that urban environmental stressors, especially air pollution, can have on wildlife. For example, nitrogen oxides (NOx), released during incomplete combustion of fossil fuels, are highly potent pro-oxidants, thus predicted to affect either the protective antioxidants and/or cause oxidative damage to bio-molecules...
December 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29223086/perceived-versus-actual-water-quality-community-studies-in-rural-oaxaca-mexico
#3
Lewis Stetson Rowles, Reinaldo Alcalde, Francisca Bogolasky, Soyoon Kum, Farith A Diaz-Arriaga, Craig Ayres, Anne M Mikelonis, Luis Javier Toledo-Flores, Manuel Gerardo Alonso-Gutiérrez, Maria Eufemia Pérez-Flores, Desmond F Lawler, Peter M Ward, Juana Yolanda Lopez-Cruz, Navid B Saleh
Compromised water quality risks public health, which becomes particularly acute in economically marginalized communities. Although the majority of the clean-water-deprived population resides in Sub-Saharan Africa and Asia, a significant portion (32 million) lives in Meso- and Latin-America. Oaxaca is one of the marginalized southern states of Mexico, which has experienced high morbidity from infectious diseases and also has suffered from a high rate of infant mortality. However, there has been a paucity of reports on the status of water quality of culturally diverse rural Oaxaca...
December 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29223041/understanding-motivations-for-dietary-supplementation-during-pregnancy-a-focus-group-study
#4
Lenka Malek PhD, Wendy J Umberger PhD, Maria Makrides PhD, Carmel T Collins PhD, Shao Jia Zhou PhD
OBJECTIVE: to increase understanding of psychosocial factors (behavioural, normative and control beliefs) motivating vitamin and mineral supplement use during pregnancy. DESIGN: ten focus group discussions and two in-depth interviews were conducted using a script comprising questions based on study objectives. All discussions were recorded, transcribed verbatim and analysed using a framework approach. SETTING: South Australia, Australia. SUBJECTS: 40 women aged 21-45 years who were either pregnant or<12 months postpartum...
November 26, 2017: Midwifery
https://www.readbyqxmd.com/read/29222815/evaluation-and-comparison-of-2-on-farm-tests-for-estimating-somatic-cell-count-in-quarter-milk-samples-from-lactating-dairy-cattle
#5
S A Kandeel, A A Megahed, F K Arnaout, P D Constable
BACKGROUND: The somatic cell count (SCC) is commonly used to monitor udder health and diagnose subclinical intramammary infection (IMI) in dairy cattle. HYPOTHESIS: The Somaticell test (ST) and California mastitis test (CMT) are clinically useful cow-side tests for diagnosing subclinical IMI. ANIMALS: One hundred and eleven dairy cows at dry-off and 92 cows within 4-7 days postcalving. METHODS: Quarter foremilk samples were obtained and analyzed with a DeLaval cell counter (DCC, reference method), ST, and CMT...
December 9, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29222785/neuronal-cell-morphology-in-primary-cerebellar-granule-cells-using-high-content-analysis
#6
Nicholas Radio, Steven Frank
Neurite outgrowth, one of the underlying cellular processes that defines the development and functionality of the mammalian nervous system, is also a sensitive indicator of neuronal cell health. From screening libraries of putative neurotherapeutic compounds to analyzing the millions of environmental pollutants for which we have inadequate neurotoxicity safety data, the large volume of chemical compounds that require evaluation is a major obstacle for manual imaging and analysis methods. In this context, high-content analysis (HCA) has emerged as a sensitive and accurate method for detecting changes in neuronal cell morphology within a format applicable to screening large chemical libraries...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29222728/fetal-electrocardiogram-extraction-and-analysis-using-adaptive-noise-cancellation-and-wavelet-transformation-techniques
#7
P Sutha, V E Jayanthi
Birth defect-related demise is mainly due to congenital heart defects. In the earlier stage of pregnancy, fetus problem can be identified by finding information about the fetus to avoid stillbirths. The gold standard used to monitor the health status of the fetus is by Cardiotachography(CTG), cannot be used for long durations and continuous monitoring. There is a need for continuous and long duration monitoring of fetal ECG signals to study the progressive health status of the fetus using portable devices. The non-invasive method of electrocardiogram recording is one of the best method used to diagnose fetal cardiac problem rather than the invasive methods...
December 8, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29222678/dose-responses-for-mortality-from-cerebrovascular-and-heart-diseases-in-atomic-bomb-survivors-1950-2003
#8
Helmut Schöllnberger, Markus Eidemüller, Harry M Cullings, Cristoforo Simonetto, Frauke Neff, Jan Christian Kaiser
The scientific community faces important discussions on the validity of the linear no-threshold (LNT) model for radiation-associated cardiovascular diseases at low and moderate doses. In the present study, mortalities from cerebrovascular diseases (CeVD) and heart diseases from the latest data on atomic bomb survivors were analyzed. The analysis was performed with several radio-biologically motivated linear and nonlinear dose-response models. For each detrimental health outcome one set of models was identified that all fitted the data about equally well...
December 8, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/29222670/venetoclax-for-treating-chronic-lymphocytic-leukaemia-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#9
REVIEW
Hema Mistry, Chidozie Nduka, Martin Connock, Jill Colquitt, Theodoros Mantopoulos, Emma Loveman, Renata Walewska, James Mason
Venetoclax is licensed to treat relapsed or refractory (R/R) chronic lymphocytic leukaemia (CLL). As part of the Single Technology Appraisal (STA) ID944, the National Institute for Health and Care Excellence (NICE) invited AbbVie, the manufacturer, to submit evidence on the use of venetoclax, within its licensed indication. The Evidence Review Group (ERG), Warwick Evidence, was asked to provide an independent and critical review of the submitted evidence. Evidence came from three single-arm trials in CLL patients with or without 17p deletion [del(17p])/TP53 chromosomal abnormalities...
December 8, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29222598/information-needs-of-adolescent-and-young-adult-cancer-patients-and-their-parent-carers
#10
Maria C McCarthy, Robyn McNeil, Sarah Drew, Lisa Orme, Susan M Sawyer
PURPOSE: This study aimed to explore health-related information needs of adolescent and young adults (AYAs) and their parent-carers and to examine demographic and clinical variables associated with unmet information needs, including patient activation. METHODS: In a national cross-sectional study, 196 Australian AYAs diagnosed with cancer between 15 and 25 years and within 24 months of diagnosis and 204 parent-carers reported on total and unmet needs for cancer and health-related information...
December 8, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29222351/how-are-junior-doctors-managing-patients-with-self-limiting-illnesses-at-their-first-presentation-a-video-vignette-study
#11
Eugene D'Souza, Catherine Krejany, Rosie Meng, Moyez Jiwa
PURPOSE: To conduct a video vignette survey of medical students and doctors investigating test ordering for patients presenting with self-limiting or minor illness. METHODS: Participants were shown six video vignettes of common self-limiting illnesses and invited to devise investigation and management plans for the patients' current presentation. The number of tests ordered was compared with those recommended by an expert panel. A Theory of Planned Behaviour Questionnaire explored participants' beliefs and attitudes about ordering tests in the context of self-limiting illness...
December 8, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29222227/pings-phone-based-intervention-under-nurse-guidance-after-stroke-interim-results-of-a-pilot-randomized-controlled-trial
#12
Fred Sarfo, Frank Treiber, Mulugeta Gebregziabher, Sheila Adamu, Sachin Patel, Michelle Nichols, Dominic Awuah, Asumadu Sakyi, Nyantakyi Adu-Darko, Arti Singh, Raelle Tagge, Jenkins Carolyn, Bruce Ovbiagele
BACKGROUND AND PURPOSE: Stroke exacts an immense toll in sub-Saharan Africa where there are few resources, and stroke prevention research is limited. The aim of this study is to test the feasibility and preliminary efficacy of an m-Health technology-enabled, nurse-guided intervention in improving blood pressure (BP) control among Ghanaian stroke patients within 1 month of symptom onset. METHODS: We conducted a 2-arm cluster pilot randomized controlled trial involving 60 recent stroke survivors encountered within a single tertiary medical system in Ghana...
December 8, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29222108/illicit-cigarette-sales-in-indian-cities-findings-from-a-retail-survey
#13
Rijo M John, Hana Ross
OBJECTIVE: To estimate illicit cigarette consumption in India using a modified and replicable method and compare it with estimates generated by the tobacco industry and by a commercial entity. METHODS: The study employed a modified approach to cigarette pack analysis suitable for countries with prevalent single-cigarette sales. Empty cigarette packs generated by 1 day's single-cigarette sales were collected directly from cigarette vendors in four large and four small cities covering the length and breadth of India...
December 8, 2017: Tobacco Control
https://www.readbyqxmd.com/read/29222080/the-12-item-self-report-world-health-organization-disability-assessment-schedule-whodas-2-0-administered-via-the-internet-to-individuals-with-anxiety-and-stress-disorders-a-psychometric-investigation-based-on-data-from-two-clinical-trials
#14
Erland Axelsson, Elin Lindsäter, Brjánn Ljótsson, Erik Andersson, Erik Hedman-Lagerlöf
BACKGROUND: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a widespread measure of disability and functional impairment, which is bundled with the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) for use in psychiatry. Administering psychometric scales via the Internet is an effective way to reach respondents and allow for convenient handling of data. OBJECTIVE: The aim was to study the psychometric properties of the 12-item self-report WHODAS 2...
December 8, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29221947/-the-impact-of-patient-identification-on-an-integrated-program-of-palliative-care-in-basque-country
#15
Igor Larrañaga, Jesús Millas, Myriam Soto-Gordoa, Arantzazu Arrospide, Ricardo San Vicente, Marisa Irizar, Itziar Lanzeta, Javier Mar
OBJECTIVE: Evaluate the process and the economic impact of an integrated palliative care program. DESIGN: Comparative cross-sectional study. LOCATION: Integrated Healthcare Organizations of Alto Deba and Goierri Alto-Urola, Basque Country. PARTICIPANTS: Patients dead due to oncologic and non-oncologic causes in 2012 (control group) and 2015 (intervention group) liable to need palliative care according to McNamara criteria...
December 5, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/29221944/living-uterus-donation-and-transplantation-experience-of-interest-and-screening-in-a-single-center-in-the-united-states
#16
Liza Johannesson, Kristin Wallis, E Colin Koon, Gregory J Mckenna, Tiffany Anthony, Sara G Leffingwell, Goran B Klintmalm, Robert T Gunby, Giuliano Testa
BACKGROUND: Little is known about attitudes toward uterus donation and transplantation in society and the interest of the women the treatment is aimed to assist. OBJECTIVE: This study examined the interest of recipients and living donors in our uterus transplantation program; it describes the screening protocol we developed and the results of the screening and reports demographic data and characteristics of screened candidates. STUDY DESIGN: Initial screening and evaluation included physical examinations by a gynecologist and a transplant surgeon; psychological evaluation; imaging (x-ray, computed tomography, ultrasound); blood tests; immunological testing; viral, bacterial, and fungal testing; drug screen; hormonal testing; Pap smear; urinalysis; and electrocardiogram...
December 5, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29221890/22nd-international-conference-on-medical-physics-2016-bangkok-thailand-medical-physics-propelling-global-health
#17
EDITORIAL
Virginia Tsapaki, Geoff Ibbott, Anchali Krisanachinda, Kwan-Hoong Ng, Tae-Suk Suh, Slavik Tabakov, John Damilakis
As medical technology evolves and patient needs increase, the need for well-trained and highly professional medical physicists (MPs) becomes even more urgent. The roles and responsibilities of MPs in various departments within the hospital are diverse and demanding. It is obvious that training, continuing education and professional development of MPs have become essential. One of the ways for an MP to advance his or her knowledge is to participate in conferences and congresses. Last year, the 22nd International Conference of Medical Physics (ICMP 2016) took place in Bangkok, Thailand...
December 6, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/29221787/evaluation-of-alternative-serum-biomarkers-to-monitor-the-progression-of-chronic-hbv-and-hcv-infection
#18
S Tsiomita, U Georgopoulou, P P Doumba, J Koskinas, K Adamidis, C Papaloukas, G Thyphronitis
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are among the most serious health conditions affecting about 600 million people worldwide leading to a number of severe liver diseases. Due to the lack of warning signs or mild symptoms during the early stage of the infection, a molecular signature associated with disease progression would be useful. Based on our recent paper where candidate biomarkers were determined through topological and modularity analysis of protein interaction networks (PINs), this study was focused on the evaluation of MIF, TNFRSF1A, FAS and TMSB4X as diagnostic biomarkers in chronic HBV and HCV infections...
December 5, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29221670/sociodemographic-and-obstetric-factors-related-to-symptoms-of-postpartum-depression-in-hispanic-women-in-rural-california
#19
Younglee Kim, Vivien Dee
OBJECTIVE: To investigate the relationships among sociodemographic and obstetric factors and symptoms of postpartum depression (PPD) in Hispanic women living in rural California. DESIGN: Quantitative, cross-sectional, descriptive design. SETTING: Rural southern California communities. PARTICIPANTS: A convenience sample of 223 Hispanic women, ages 18 to 42 years old, with one living infant younger than 12 months old...
December 5, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29221650/-immunohistochemistry-using-clone-ve1-is-an-economic-specific-and-sensitive-method-for-detecting-the-presence-of-brafv600e-mutations-in-melanoma
#20
M Etienne, F Oca, D Prunier-Mirebeau, A Croué, L Martin
BACKGROUND: Determination of BRAF mutation status is mandatory in the management of patients with inoperable stage IIIC or stage IV melanoma. Currently, molecular biology (MB) has been validated for detecting the presence of BRAF mutations. OBJECTIVE: To compare the sensitivity, specificity and cost of immunohistochemistry (IHC) (clone VE1) versus BM methods (qPCR and Sanger sequencing). PATIENTS AND METHODS: All the samples for which BRAF mutation status was requested between March 2013 and February 2015 at the cellular and molecular analysis laboratory of the Angers Hospital were included retrospectively and consecutively...
December 5, 2017: Annales de Dermatologie et de Vénéréologie
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