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https://www.readbyqxmd.com/read/28539007/videolaryngoscopy-versus-direct-laryngoscopy-for-tracheal-intubation-in-children-excluding-neonates
#1
REVIEW
Ibtihal S Abdelgadir, Robert S Phillips, Davinder Singh, Michael P Moncreiff, Joanne L Lumsden
BACKGROUND: Direct laryngoscopy is the method currently used for tracheal intubation in children. It occasionally offers unexpectedly poor laryngeal views. Indirect laryngoscopy involves visualizing the vocal cords by means other than obtaining a direct sight, with the potential to improve outcomes. We reviewed the current available literature and performed a meta-analysis to compare direct versus indirect laryngoscopy, or videolaryngoscopy, with regards to efficacy and adverse effects...
May 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28527873/comparison-of-xenon-with-led-illuminant-in-difficult-and-inhalation-injury-airway-scenario-a-randomized-crossover-manikin-study
#2
Andreas Moritz, Johannes Prottengeier, Joachim Schmidt
PURPOSE: The purpose of this study was to compare the effectiveness of a Xenon halogen with a light-emitting diode (LED) laryngoscope light handle in a difficult airway scenario, as well as in an inhalation injury airway scenario that combines a difficult airway and a limited view. METHODS: We recruited forty-two anesthetists into a randomized crossover trial. Each performed tracheal intubation (TI) with a Xenon halogen and a LED light handle in the two manikin scenarios...
May 8, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28525401/glidescope-versus-airtraq-dl-for-double-lumen-tracheal-tube-insertion-in-patients-with-a-predicted-or-known-difficult-airway-a-randomised-study
#3
Olivier Belze, Evan Lepage, Yvan Bazin, Pierre Kerourin, Jacques Fusciardi, Francis Remérand, Fabien Espitalier
BACKGROUND: Double-lumen tracheal tube (DLT) insertion can be managed with videolaryngoscopes such as the Glidescope or indirect laryngoscopes like the Airtraq DL. No study has compared both devices when a difficult intubation is predicted. OBJECTIVE: Our hypothesis was that the Glidescope is superior to the Airtraq for double-lumen tube insertion in patients with a predicted or known difficult airway. DESIGN: Adult patients scheduled for elective thoracic surgery with a predicted risk (evaluated preoperatively using the Arné score) or history of difficult intubation were allocated randomly to one of two groups: a Glidescope group and an Airtraq group...
May 19, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28515522/comparison-of-airtraq%C3%A2-mccoy%C3%A2-and-macintosh-laryngoscopes-for-endotracheal-intubation-in-patients-with-cervical-spine-immobilisation-a-randomised-clinical-trial
#4
Vinod Hosalli, B K Arjun, Uday Ambi, Shivanand Hulakund
BACKGROUND AND AIMS: The study aimed at comparing the performance of the novel optical Airtraq™ laryngoscope with the McCoy™ and conventional Macintosh laryngoscopes for ease of endotracheal intubation in patients with neck immobilisation using manual inline axial cervical spine stabilisation (MIAS) technique. METHODS: Ninety consenting American Society of Anaesthesiologist's physical status I-II patients, aged 18-60 years, scheduled for various surgeries requiring tracheal intubation were randomly assigned into three groups of thirty each to undergo intubation with Macintosh, Airtraq™, or McCoy™ laryngoscope with neck immobilisation by MIAS technique...
April 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28500233/nanoformulation-of-olaparib-amplifies-parp-inhibition-and-sensitizes-pten-tp53-deficient-prostate-cancer-to-radiation
#5
Anne L van de Ven, Shifalika Tangutoori, Paige Baldwin, Ju Qiao, Codi Gharagouzloo, Nina Seitzer, John G Clohessy, G Mike Makrigiorgos, Robert Cormack, Pier Paolo Pandolfi, Srinivas Sridhar
The use of PARP inhibitors in combination with radiation therapy is a promising strategy to locally enhance DNA-damage in tumors. Here we show that radiation-resistant cells and tumors derived from a Pten/Trp53-deficient mouse model of advanced prostate cancer are rendered radiation-sensitive following treatment with NanoOlaparib, a lipid-based injectable nanoformulation of Olaparib. This enhancement in radiosensitivity is accompanied by radiation dose-dependent changes in γ-H2AX expression and is specific to NanoOlaparib alone...
May 12, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28487139/a-multicenter-randomized-trial-of-ramped-position-versus-sniffing-position-during-endotracheal-intubation-of-critically-ill-adults
#6
Matthew W Semler, David R Janz, Derek W Russell, Jonathan D Casey, Robert J Lentz, Aline N Zouk, Bennett P deBoisblanc, Jairo I Santanilla, Yasin A Khan, Aaron M Joffe, William S Stigler, Todd W Rice
BACKGROUND: Hypoxemia is the most common complication during endotracheal intubation of critically ill adults. Intubation in the ramped position has been hypothesized to prevent hypoxemia by increasing functional residual capacity and decreasing the duration of intubation, but has never been studied outside of the operating room. METHODS: Multicenter, randomized trial comparing ramped position (head of the bed elevated to 25 degrees) to sniffing position (torso supine, neck flexed, head extended) among 260 adults undergoing endotracheal intubation by Pulmonary and Critical Care Medicine fellows in four intensive care units between July 22, 2015 and July 19, 2016...
May 6, 2017: Chest
https://www.readbyqxmd.com/read/28479280/pelagic-and-benthic-communities-of-the-antarctic-ecosystem-of-potter-cove-genomics-and-ecological-implications
#7
REVIEW
D Abele, S Vazquez, A G J Buma, E Hernandez, C Quiroga, C Held, S Frickenhaus, L Harms, J L Lopez, E Helmke, W P Mac Cormack
Molecular technologies are more frequently applied in Antarctic ecosystem research and the growing amount of sequence-based information available in databases adds a new dimension to understanding the response of Antarctic organisms and communities to environmental change. We apply molecular techniques, including fingerprinting, and amplicon and metagenome sequencing, to understand biodiversity and phylogeography to resolve adaptive processes in an Antarctic coastal ecosystem from microbial to macrobenthic organisms and communities...
May 4, 2017: Marine Genomics
https://www.readbyqxmd.com/read/28445110/normobaric-hypoxia-increases-the-growth-hormone-response-to-maximal-resistance-exercise-in-trained-men
#8
Dean Filopoulos, Stuart J Cormack, Douglas G Whyte
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82 ± 2%) and normoxia (NOR; FiO2 0.21, SpO2 98 ± 0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum...
April 26, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28443579/determining-the-efficiency-of-different-preoperative-difficult-intubation-tests-on-patients-undergoing-caesarean-section
#9
İlker Yıldırım, Mehmet Turan İnal, Dilek Memiş, F Nesrin Turan
BACKGROUND: Pregnancy induced anatomical and physiological changes in the airway makes airway management difficult in obstetric patients, thus the preoperative evaluation of the airway is important for obstetric patients. AIMS: The first aim was determine the effectiveness of the modified mallampati test, the interincisor, sternomental, thyromental distances, the upper limb bite tests and the second aim was to access the effectiveness of the combination of the upper limb bite test with the other tests in obstetric patients...
April 13, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28443560/advances-in-nutrition-of-the-newborn-infant
#10
REVIEW
Jane E Harding, Barbara E Cormack, Tanith Alexander, Jane M Alsweiler, Frank H Bloomfield
Nutrition of newborn infants, particularly of those born preterm, has advanced substantially in recent years. Extremely preterm infants have high nutrient demands that are challenging to meet, such that growth faltering is common. Inadequate growth is associated with poor neurodevelopmental outcomes, and although improved early growth is associated with better cognitive outcomes, there might be a trade-off in terms of worse metabolic outcomes, although the contribution of early nutrition to these associations is not established...
April 22, 2017: Lancet
https://www.readbyqxmd.com/read/28422546/competition-sleep-is-not-compromised-compared-to-habitual-in-elite-australian-footballers
#11
Benita J Lalor, Shona L Halson, Jacquie Tran, Justin G Kemp, Stuart J Cormack
PURPOSE: To assess the impact of match start time and days relative to match compared to the habitual sleep characteristics of elite Australian Football (AF) players. METHODS: 45 elite male AF players were assessed during the pre-season (habitual) and across four home matches during the season. Players wore an activity monitor the night before (-1), night of (0), one night after (+1), and two nights (+2) after each match and completed a self-reported rating of sleep quality...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28412838/self-reported-sleep-complaints-are-associated-with-adverse-health-outcomes-cross-sectional-analysis-of-the-2002-03-new-zealand-health-survey
#12
Sarah-Jane Paine, Ricci Harris, Donna Cormack, James Stanley
OBJECTIVE: The aim was to investigate the prevalence of self-reported sleep complaints in New Zealand adults and determine the independent association of sleep complaints with adverse health outcomes. DESIGN: We used 2002/03 New Zealand Health Survey data (n = 12,500 adults, ≥15 years). The prevalence of self-reported sleep complaints was estimated by ethnicity. The relationship between sleep complaints and mental health, physical health and health risk behaviors were investigated using multivariable logistic regression models...
April 15, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28408081/-nondepolarizing-muscle-relaxant-improves-direct-laryngoscopy-view-with-no-effect-on-face-mask-ventilation
#13
Marwan S Rizk, Salah M Zeineldine, Mohamad F El-Khatib, Vanda G Yazbeck-Karam, Sophie D Ayoub, Pierre K Bou-Khalil, Elie Abi-Nader, Marc M Ghabach, Chakib M Ayoub
BACKGROUND: Difficult or impossible face mask ventilation complicated with difficult tracheal intubation during anesthesia induction occurs in 0.4% of adult anesthesia cases, possibly leading to life-threatening complications. Because of such catastrophes, muscle relaxants have been recommended to be administered after confirming adequate face mask ventilation without a solid scientific validation of this principal. METHODS: In this observational study, the ease of ventilation and the scores of direct laryngoscopy views before and after administration of cisatracurium were assessed in ninety young healthy adults, without anesthetic risks and without foreseen difficult intubation and who were scheduled for general elective surgeries...
April 10, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28404553/airway-emergencies-presenting-to-the-paediatric-emergency-department-requiring-advanced-management-techniques
#14
Leopold Simma, Domenic Cincotta, Stefan Sabato, Elliot Long
BACKGROUND: Airway emergencies presenting to the emergency department (ED) are usually managed with conventional equipment and techniques. The patient group managed urgently in the operating room (OR) has not been described. AIMS: This study aims to describe a case series of children presenting to the ED with airway emergencies managed urgently in the OR, particularly the anaesthetic equipment and techniques used and airway findings. METHODS: A retrospective cohort study undertaken at The Royal Children's Hospital, Melbourne, Australia...
April 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28397770/prospecting-biotechnologically-relevant-monooxygenases-from-cold-sediment-metagenomes-an-in-silico-approach
#15
Matías A Musumeci, Mariana Lozada, Daniela V Rial, Walter P Mac Cormack, Janet K Jansson, Sara Sjöling, JoLynn Carroll, Hebe M Dionisi
The goal of this work was to identify sequences encoding monooxygenase biocatalysts with novel features by in silico mining an assembled metagenomic dataset of polar and subpolar marine sediments. The targeted enzyme sequences were Baeyer-Villiger and bacterial cytochrome P450 monooxygenases (CYP153). These enzymes have wide-ranging applications, from the synthesis of steroids, antibiotics, mycotoxins and pheromones to the synthesis of monomers for polymerization and anticancer precursors, due to their extraordinary enantio-, regio-, and chemo- selectivity that are valuable features for organic synthesis...
April 9, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28393782/thyromental-height-test-for-prediction-of-difficult-laryngoscopy-in-patients-undergoing-coronary-artery-bypass-graft-surgical-procedure
#16
Nilesh Jain, Sucharita Das, Muralidhar Kanchi
BACKGROUND: Patients undergoing coronary artery bypass graft (CABG) procedures have higher incidence of difficult laryngoscopy and intubation than general surgery population. Accurate prediction of difficult laryngoscopy in CABG patients is desirable to reduce the hemodynamic response and myocardial oxygen requirements. Recently, thyromental height test (TMHT) has been proposed as one of the highly sensitive and specific bedside tests to predict difficult airway. We, in our prospective observational study, evaluated the accuracy of the TMHT in predicting difficult laryngoscopy...
April 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28376741/neck-circumference-to-inter-incisor-gap-ratio-a-new-predictor-of-difficult-laryngoscopy-in-cervical-spondylosis-patients
#17
Yong-Zheng Han, Yang Tian, Mao Xu, Cheng Ni, Min Li, Jun Wang, Xiang-Yang Guo
BACKGROUND: Preoperative airway assessment help anticipate a difficult airway. We hypothesized that a close association existed between difficult laryngoscopy and the neck circumference/inter-incisor gap ratio (RNIIG). Our aim was to determine its utility in predicting difficult laryngoscopy in cervical spondylosis patients. METHODS: Two hundred thirteen consecutive patients, aged 20-70 years, scheduled to undergo cervical spine surgery under general anesthesia, were recruited...
April 4, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28355228/indo-pacific-humpback-dolphins-sousa-chinensis-in-hong-kong-modelling-demographic-parameters-with-mark-recapture-techniques
#18
Stephen C Y Chan, Leszek Karczmarski
Indo-Pacific humpback dolphins (Sousa chinensis) inhabiting Hong Kong waters are thought to be among the world's most anthropogenically impacted coastal delphinids. We have conducted a 5-year (2010-2014) photo-ID study and performed the first in this region comprehensive mark-recapture analysis applying a suite of open population models and robust design models. Cormack-Jolly-Seber (CJS) models suggested a significant transient effect and seasonal variation in apparent survival probabilities as result of a fluid movement beyond the study area...
2017: PloS One
https://www.readbyqxmd.com/read/28341185/c-mac-compared-with-direct-laryngoscopy-for-intubation-in-patients-with-cervical-spine-immobilization-a-manikin-trial
#19
Jacek Smereka, Jerzy R Ladny, Amanda Naylor, Kurt Ruetzler, Lukasz Szarpak
INTRODUCTION: The aim of this study was to compare C-MAC videolaryngoscopy with direct laryngoscopy for intubation in simulated cervical spine immobilization conditions. METHODS: The study was designed as a prospective randomized crossover manikin trial. 70 paramedics with <5years of medical experience participated in the study. The paramedics attempted to intubate manikins in 3 airway scenarios: normal airway without cervical immobilization (Scenario A); manual inline cervical immobilization (Scenario B); cervical immobilization using cervical extraction collar (Scenario C)...
March 16, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28337769/accuracy-intra-and-inter-rater-reliability-of-three-scoring-systems-for-the-glottic-view-at-videolaryngoscopy
#20
E J O'Loughlin, A D Swann, J D English, R Ramadas
An accurate and reproducible recording of laryngoscopic view at tracheal intubation is an important aspect of anaesthetic practice. Unlike direct laryngoscopy, in which the view achieved by the line of sight directly relates to the ease of intubating the trachea, videolaryngoscopy can create a situation in which the view is good, but intubation difficult or impossible. Communicating this to a subsequent anaesthetist is important. We compared three scoring systems: Cormack and Lehane; POGO (percentage of glottic opening); and the Fremantle score, as used by 74 critical care doctors rating 30 anonymised videos of videolaryngoscopic intubations...
March 24, 2017: Anaesthesia
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