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https://www.readbyqxmd.com/read/28725251/custom-made-micro-applicators-for-high-dose-rate-brachytherapy-treatment-of-chronic-psoriasis
#1
Ivan M Buzurovic, Desmond A O'Farrell, Mandar S Bhagwat, Jorgen L Hansen, Thomas C Harris, Scott Friesen, Robert A Cormack, Phillip M Devlin
PURPOSE: In this study, we present the treatment of the psoriatic nail beds of patients refractory to standard therapies using high-dose-rate (HDR) brachytherapy. The custom-made micro applicators (CMMA) were designed and constructed for radiation dose delivery to small curvy targets with complicated topology. The role of the HDR brachytherapy treatment was to stimulate the T cells for an increased immune response. MATERIAL AND METHODS: The patient diagnosed with psoriatic nail beds refractory to standard therapies received monthly subunguinal injections that caused significant pain and discomfort in both hands...
June 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28714739/relationships-between-model-predicted-and-actual-match-performance-in-professional-australian-footballers-during-an-in-season-training-macrocycle
#2
Stuart R Graham, Stuart Cormack, Gaynor Parfitt, Roger Eston
PURPOSE: To assess and compare the validity of internal and external Australian Football (AF) training load measures for predicting match exercise intensity (MEI.min(-1)) and player rank score (PR(Score)) using a variable dose-response model. METHODS: 25 professional AF players (23 ± 3 y, 188.3 ± 7.2 cm and 87.7 ± 8.4 kg) completed a 24-week in-season macrocycle. In-season internal training and match load was quantified using session-RPE (sRPE) and external load from satellite and accelerometer data...
July 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28712013/a-novel-approach-to-an-automated-needle-insertion-in-brachytherapy-procedures
#3
Ivan M Buzurovic, Slavisa Salinic, Peter F Orio, Paul L Nguyen, Robert A Cormack
One of the most challenging phases in interstitial brachytherapy is the placement of the needles. In these medical procedures, the needles are inserted inside the tissue to guide the positioning of the radioactive sources. The low-dose-rate radioactive sources are placed inside the tissue permanently, whereas a radioactive source in the high-dose-rate brachytherapy is temporarily placed in the desired positions so that the delivery of the prescription dose to the clinical targets can be achieved. Consequently, the precise needle placement directly influences the radiation dose delivery and the treatment outcomes of patients...
July 15, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28702706/metagenomic-analysis-of-subtidal-sediments-from-polar-and-subpolar-coastal-environments-highlights-the-relevance-of-anaerobic-hydrocarbon-degradation-processes
#4
Fernando Espínola, Hebe M Dionisi, Sharon Borglin, Colin J Brislawn, Janet K Jansson, Walter P Mac Cormack, JoLynn Carroll, Sara Sjöling, Mariana Lozada
In this work, we analyzed the community structure and metabolic potential of sediment microbial communities in high-latitude coastal environments subjected to low to moderate levels of chronic pollution. Subtidal sediments from four low-energy inlets located in polar and subpolar regions from both Hemispheres were analyzed using large-scale 16S rRNA gene and metagenomic sequencing. Communities showed high diversity (Shannon's index 6.8 to 10.2), with distinct phylogenetic structures (<40% shared taxa at the Phylum level among regions) but similar metabolic potential in terms of sequences assigned to KOs...
July 12, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28694175/daily-consumption-of-methylene-blue-reduces-attentional-deficits-and-dopamine-reduction-in-a-6-ohda-model-of-parkinson-s-disease
#5
Elizabeth S Smith, Madeline E Clark, Gwendolyn A Hardy, David J Kraan, Elisa Biondo, F Gonzalez-Lima, Lawrence K Cormack, Marie Monfils, Hongjoo J Lee
Recently, alternative drug therapies for Parkinson's disease (PD) have been investigated as there are many shortcomings of traditional dopamine-based therapies including difficulties in treating cognitive and attentional dysfunction. A promising therapeutic avenue is to target mitochondrial dysfunction and oxidative stress in PD. One option might be the use of methylene blue (MB), an antioxidant and metabolic enhancer. MB has been shown to improve cognitive function in both intact rodents and rodent disease models...
July 8, 2017: Neuroscience
https://www.readbyqxmd.com/read/28687543/injury-epidemiology-of-tennis-players-at-the-2011-2016-australian-open-grand-slam
#6
Danielle T Gescheit, Stuart J Cormack, Rob Duffield, Stephanie Kovalchik, Tim O Wood, Melanie Omizzolo, Machar Reid
AIM: To examine the epidemiology and in-event treatment frequency of injury at the 2011-2016 Australian Open tournaments. METHODS: Injury incidence was defined as a medical consultation by a tournament physician and in-event treatment frequency as the mean total number of follow-up medical/physiotherapy consultations (2013-2016 tournaments only). Data were collated by sex, injury region and type and reported as frequencies per 10 000 game exposures. Incidence rate s± 95% CI and rate ratios were used to test effects for injury, sex and year...
July 7, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28682897/previsional-space-during-direct-laryngoscopy-implication-in-the-difficult-laryngoscopy
#7
Seongjoo Park, Ji-Won Han, Sukwon Cha, Sung-Hee Han, Jin-Hee Kim
The laryngoscope should displace oral soft tissues forward out of the operator's vision. Therefore, the space in front of the view may be critical for determining the laryngoscopic view. The aim was to investigate the difference in the previsional space during difficult versus easy laryngoscopy (EL).Under general anesthesia, digital photographs of the lateral view of the head and neck were taken in the horizontal sniffing position, after head extension, and during laryngoscopy with a defined force (50 N)...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28676767/when-is-a-sprint-a-sprint-a-review-of-the-analysis-of-team-sport-athlete-activity-profile
#8
REVIEW
Alice J Sweeting, Stuart J Cormack, Stuart Morgan, Robert J Aughey
The external load of a team-sport athlete can be measured by tracking technologies, including global positioning systems (GPS), local positioning systems (LPS), and vision-based systems. These technologies allow for the calculation of displacement, velocity and acceleration during a match or training session. The accurate quantification of these variables is critical so that meaningful changes in team-sport athlete external load can be detected. High-velocity running, including sprinting, may be important for specific team-sport match activities, including evading an opponent or creating a shot on goal...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28662428/bacterial-communities-and-chemical-parameters-in-soils-and-coastal-sediments-in-response-to-diesel-spills-at-carlini-station-antarctica
#9
Susana Vázquez, Patrick Monien, Roberto Pepino Minetti, Jutta Jürgens, Antonio Curtosi, Julia Villalba Primitz, Stephan Frickenhaus, Doris Abele, Walter Mac Cormack, Elisabeth Helmke
A diesel spill occurring at Carlini Station (King George Island (Isla 25 de Mayo), South Shetland Islands) in 2009 started the study of the fate of the hydrocarbons and their effect on the bacterial communities of the Potter Cove ecosystem. Soils and sediments were sampled across the 200-meter long diesel plume towards Potter Cove four and 15months after the spill. The sampling revealed a second fuel leakage from an underground pipeline at the spill site. The hydrocarbon fraction spilt over frozen and snow-covered ground reached the sea and dispersed with the currents...
June 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28655086/-clinical-study-of-smt-%C3%A2-video-laryngoscope-with-difficult-airway-intubation-in-emergency-department
#10
J H Yu, Y Wang
Objective: To observe the clinical feasibility and security of SMT-Ⅱ video laryngoscope in difficult airway intubation in emergency department. Methods: This study took 90 adults with difficult airway who were admitted to the rescue room of Jingxi court of Beijing Chao-Yang Hospital, Capital Medical University from January 2015 to December 2016.The patients were randomly divided into 2 groups(SMT-Ⅱ video laryngoscope group: n=45, Macintosh direct laryngoscope group: n=45), which were treated with endotracheal intubation and ventilator assisted ventilation...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28637820/dynamic-mechanisms-of-visually-guided-3d-motion-tracking
#11
Kathryn L Bonnen, Alexander C Huk, Lawrence Kevin Cormack
The continuous perception of motion-through-depth is critical both for navigation and interacting with objects in a dynamic three dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to frontoparallel motion. Observers manually tracked a stereoscopic target as it moved in a 3D Brownian random walk. We found that continuous tracking of motion-through-depth was selectively impaired, showing different spatiotemporal properties compared to frontoparallel motion tracking...
June 21, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28626978/a-fast-multi-target-inverse-treatment-planning-strategy-optimizing-dosimetric-measures-for-high-dose-rate-hdr-brachytherapy
#12
Christian V Guthier, Antonio L Damato, Akila N Viswanathan, Juergen W Hesser, Robert A Cormack
PURPOSE: In this study, we introduce a novel, fast, inverse treatment planning strategy for interstitial high-dose-rate (HDR) brachytherapy with multiple regions of interest solely based on dose-volume-histogram-related dosimetric measures (DMs). METHODS: We present a new problem formulation of the objective function that approximates the indicator variables of the standard DM optimization problem with a smooth logistic function. This problem is optimized by standard gradient-based methods...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28620866/high-levels-of-igf-1-predict-difficult-intubation-of-patients-with-acromegaly
#13
Yu Zhang, Xiaopeng Guo, Lijian Pei, Zhuhua Zhang, Gang Tan, Bing Xing
PURPOSE: To investigate the characteristics of difficult intubation and identify novel efficient predictors in patients with acromegaly. METHODS: Patients with either untreated acromegaly or non-functional pituitary adenomas were enrolled. Patients with acromegaly underwent hormone assays, upper airway computed tomography and magnetic resonance imaging examinations and preoperative overnight polysomnography. The modified Mallampati classification, mouth opening, neck circumference, and neck extension were assessed, and the Cormack-Lehane grades and the time of tracheal intubation were recorded...
August 2017: Endocrine
https://www.readbyqxmd.com/read/28607336/cervical-spine-motion-during-tracheal-intubation-with-king-visiontm-video-laryngoscopy-and-conventional-laryngoscopy-a-crossover-randomized-study
#14
Mohamed R El-Tahan, Samah El Kenany, Alaa M Khidr, Abdulmohsen A Al Ghamdi, Ahmed M Tawfik, Abdullah S Al Mulhim
BACKGROUND: The King VisonTM (KVL) videolaryngoscope with a wide field of view could potentially reduce cervical spine motion during intubation. We aimed to compare the extent of cervical spine movement during laryngoscopy using the KVL and Macintosh laryngoscopes. METHODS: Following ethical approval, 29 patients with a normal cervical spine requiring general anesthesia and tracheal intubation were randomly subjected to both KVL and Macintosh laryngoscopy in a crossover...
June 12, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28588178/assessment-of-difficulties-associated-with-endotracheal-intubation-using-modified-mallampati-and-upper-lip-bite-test
#15
D Banik, L Ray, A K Akhtaruzzaman, D K Bhowmick, M S Hossain, M S Islam, M F Haque
This study was aimed at finding the parameters for prediction of difficulty in endotracheal intubation, that are easy to examine and that could better predict difficulty. The current observational prospective, cross sectional study was conducted in the department of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2015 to September 2015 comprising 180 patient of both sexes requiring endotracheal intubation were arranged into two groups, Group A: Modified Mallampati test Group and Group B: Modified Mallampati & upper lip bite test group (combined) Assessment of difficulty in intubation was done by Cormack & Lehane direct Laryngoscopic grading...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28581411/computerized-system-for-safety-verification-of-external-beam-radiation-therapy-planning
#16
Clay Holdsworth, Jacek Kukluk, Christina Molodowitch, Maria Czerminska, Cindy Hancox, Robert A Cormack, Kevin Beaudette, Joseph H Killoran
PURPOSE: To report an assessment of in-house software, Verifier, developed to improve efficacy and efficiency of the radiation therapy (RT) treatment planning process and quality control review (QCR). METHODS AND MATERIALS: Radiation therapy plan parameters retrieved from our treatment planning database are used by automated tests to give 75 types of warnings, such as prescription and plan discrepancies. The software is continuously updated on the basis of new issues, ideas, and planning policies...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28577883/corrigendum-to-comparison-of-outcomes-for-mr-guided-versus-ct-guided-high-dose-rate-interstitial-brachytherapy-in-women-with-locally-advanced-carcinoma-of-the-cervix-gynecol-oncol-145-2017-284-290
#17
Sophia C Kamran, Matthias M Manuel, Linda P Cho, Antonio L Damato, Ehud J Schmidt, Clare Tempany, Robert A Cormack, Akila N Viswanathan
No abstract text is available yet for this article.
May 31, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28564686/bayesian-depth-estimation-from-monocular-natural-images
#18
Che-Chun Su, Lawrence K Cormack, Alan C Bovik
Estimating an accurate and naturalistic dense depth map from a single monocular photographic image is a difficult problem. Nevertheless, human observers have little difficulty understanding the depth structure implied by photographs. Two-dimensional (2D) images of the real-world environment contain significant statistical information regarding the three-dimensional (3D) structure of the world that the vision system likely exploits to compute perceived depth, monocularly as well as binocularly. Toward understanding how this might be accomplished, we propose a Bayesian model of monocular depth computation that recovers detailed 3D scene structures by extracting reliable, robust, depth-sensitive statistical features from single natural images...
May 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28539007/videolaryngoscopy-versus-direct-laryngoscopy-for-tracheal-intubation-in-children-excluding-neonates
#19
REVIEW
Ibtihal S Abdelgadir, Robert S Phillips, Davinder Singh, Michael P Moncreiff, Joanne L Lumsden
BACKGROUND: Direct laryngoscopy is the method currently used for tracheal intubation in children. It occasionally offers unexpectedly poor laryngeal views. Indirect laryngoscopy involves visualizing the vocal cords by means other than obtaining a direct sight, with the potential to improve outcomes. We reviewed the current available literature and performed a meta-analysis to compare direct versus indirect laryngoscopy, or videolaryngoscopy, with regards to efficacy and adverse effects...
May 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28527873/comparison-of-xenon-with-led-illuminant-in-difficult-and-inhalation-injury-airway-scenario-a-randomized-crossover-manikin-study
#20
Andreas Moritz, Johannes Prottengeier, Joachim Schmidt
PURPOSE: The purpose of this study was to compare the effectiveness of a Xenon halogen with a light-emitting diode (LED) laryngoscope light handle in a difficult airway scenario, as well as in an inhalation injury airway scenario that combines a difficult airway and a limited view. METHODS: We recruited forty-two anesthetists into a randomized crossover trial. Each performed tracheal intubation (TI) with a Xenon halogen and a LED light handle in the two manikin scenarios...
May 8, 2017: American Journal of Emergency Medicine
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