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Vijay M Ravindra, Jayson A Neil, Lubdha M Shah, Richard H Schmidt, Erica F Bisson
BACKGROUND: Neurosurgeons are frequently involved in the management of patients with traumatic frontal sinus injury; however, management options and operative techniques can vary significantly. In this study, the authors review the current literature and retrospectively review the clinical series at a single tertiary referral center. METHODS: After Institutional Review Board approval, the medical records and computed tomographic (CT) imaging of patients whose traumatic frontal sinus fractures were treated surgically at the University of Utah were retrospectively reviewed...
2015: Surgical Neurology International
F H Regan Nee Ashley, J Hockenhull, J C Pritchard, A E Waterman-Pearson, H R Whay
INTRODUCTIONS: Working donkeys are at risk of developing multiple, acute and chronic health problems. The ability to recognise and assess pain in donkeys associated with these health problems is important for people responsible for their care and treatment, including owners and veterinary or animal health workers. AIMS AND OBJECTIVES: The aims of this study were firstly to quantify the prevalence of a range of clinical abnormalities within a sample of working donkeys; and secondly to find out whether these abnormalities were associated with potential behavioural indicators of pain...
2015: Veterinary Record Open
C Hänsel, K Mertens, M C Elschner, F Melzer
INTRODUCTION: Brucella suis is the causative agent of brucellosis in suidae and is differentiated into five biovars (bv). Biovars 1 and 3 possess zoonotic potential and can infect humans, whereas biovar 2 represents the main source of brucellosis in feral and domestic pigs in Europe. Both aspects, the zoonotic threat and the economic loss, emphasize the necessity to monitor feral and domestic pig populations. Available serological or PCR based methods lack sensitivity and specificity...
2015: Veterinary Record Open
F J Pallarés, C Lasa, M Roozen, G Ramis
OBJECTIVES: The purpose of this study was to investigate the efficacy of tylvalosin (Aivlosin Water Soluble Granules, ECO Animal Health) in drinking water for control of Mycoplasma hyopneumoniae (M hyo) on a farm with chronic enzootic pneumonia (EP) problems and high prevalence of mycoplasma-like lesions at slaughter. DESIGN: On a 4000-sow farm in the southeast of Spain, 1500 animals of same age were randomly divided into two groups: 900 pigs in the treated group (TG) and 600 pigs in the non-treated control group (CG)...
2015: Veterinary Record Open
Heloisa Cristina Silva, Nancy Prette, Welber Daniel Zanetti Lopes, Cláudio Alessandro M Sakamoto, Carolina Buzzulini, Thais Rabelo Dos Santos, Breno Cayeiro Cruz, Weslen F Pires Teixeira, Gustavo Felippelli, Rafael Silveira Carvalho, Willian Giquelin Maciel, Vando Edésio Soares, Alvimar José da Costa
The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole...
2015: Veterinary Record Open
S Bonardi, I Alpigiani, R Tozzoli, A Vismarra, V Zecca, C Greppi, C Bacci, I Bruini, F Brindani
INTRODUCTION: Ruminants are regarded as the natural reservoir for Shiga toxin-producing Escherichia coli (STEC), especially of serogroup O157. MATERIALS AND METHODS: During 2011 and 2012, 320 samples (160 faecal samples from the rectum and 160 hide samples from the brisket area) were collected from 160 cattle at slaughter in Northern Italy during warm months (May to October). Cattle were reared in different farms and their age at slaughter ranged between nine months and 15 years, most of them being culled cattle (median age: six years; average age: 4...
2015: Veterinary Record Open
L Mendoza, D Piquemal, J P Lejeune, L Vander Heyden, F Noguier, R Bruno, C Sandersen, D Serteyn
INTRODUCTION: Osteochondrosis (OC) is a developmental disease in horses which has a significant impact on the horse's welfare and performance. The early disturbance in the process of endochondral ossification progresses to inflammatory and repair processes in older horses. Previously, differentially expressed genes in leukocytes of OC-affected horses have been identified. The aim of the present study is to detect age-related changes in these differentially expressed genes. MATERIALS AND METHODS: The expression of OC-related genes was analysed by real-time PCR and subsequent statistical analysis (ΔΔCT) in the leukocytes of 135 Belgian Warmblood horses divided into three different age groups: <12 months (n=47), 18-24 months (n=50) >30 months (n=38)...
2015: Veterinary Record Open
I Aytekin, H Aksit, A Sait, F Kaya, D Aksit, M Gokmen, A Unsal Baca
INTRODUCTION: Bluetongue (BT) is a non-contagious infectious disease of ruminants. The disease agent bluetongue virus (BTV) is classified in the Reoviridae family Orbivirus. AIMS AND OBJECTIVES: The aim of this study was to determine serum malondialdehyde (MDA), total antioxidative stres (TAS), total sialic acid (TSA), ceruloplasmin, triglyceride, alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), cholesterol, creatinine, albumin, and total protein levels in sheep with and without bluetongue (BT)...
2015: Veterinary Record Open
Lyndal Trevena
Smartphone technology is nascent compared to other technologies; however, it has shown an unprecedented uptake amongst lay consumers and professionals. This article presents the history, components, and key features of smartphones, as well as their related concepts and how they work, and it also delineates the process of smartphone applications (apps) development and publishing in the app stores. It also describes and discusses smartphone technology utilisation for health consumers, healthcare professionals, and health researchers, as well as the regulations of health-related apps...
2015: Online Journal of Public Health Informatics
Jacob Krive, Joel S Shoolin, Steven D Zink
OBJECTIVE: Evidence-based sets of medical orders for the treatment of patients with common conditions have the potential to induce greater efficiency and convenience across the system, along with more consistent health outcomes. Despite ongoing utilization of order sets, quantitative evidence of their effectiveness is lacking. In this study, conducted at Advocate Health Care in Illinois, we quantitatively analyzed the benefits of community acquired pneumonia order sets as measured by mortality, readmission, and length of stay (LOS) outcomes...
2015: Online Journal of Public Health Informatics
C Freitag, C Noble, J Fritzsche, F Persson, M Reiter-Schad, A N Nilsson, A Granéli, T Ambjörnsson, K U Mir, J O Tegenfeldt
The contiguity and phase of sequence information are intrinsic to obtain complete understanding of the genome and its relationship to phenotype. We report the fabrication and application of a novel nanochannel design that folds megabase lengths of genomic DNA into a systematic back-and-forth meandering path. Such meandering nanochannels enabled us to visualize the complete 5.7 Mbp (1 mm) stained DNA length of a Schizosaccharomyces pombe chromosome in a single frame of a CCD. We were able to hold the DNA in situ while implementing partial denaturation to obtain a barcode pattern that we could match to a reference map using the Poland-Scheraga model for DNA melting...
July 2015: Biomicrofluidics
Jessica R Lichter, Lawrence B Marr, Dennis E Schilling, Mark E Hudson, Robert H Boretsky, Roxana F Barad, Jacques E Chelly
INTRODUCTION: Corneal abrasions (CAs) are the most prevalent ocular injuries in the perioperative period. Previously, patients at our community hospital would wait for an ophthalmologist to be available to manage these minor injuries. To decrease this waiting period - and thereby increase patient satisfaction - we developed an anesthesiology-based protocol to manage minor CAs arising in the recovery room. The current study sought to assess this protocol's efficacy as well as further establish the incidence and some risk factors of CA...
2015: Clinical Ophthalmology
M F Freshwater
The purpose of medical journals is to disseminate information. This is achieved in a different manner than ordinary conversation. Conversation has the advantage over the virtual or printed page because the listener can immediately request clarification of any ambiguities. Common ambiguities in medical writing include words and phrases that are statistically incorrect, potentially inflammatory or logically flawed. Statistically incorrect words include association, average, incidence, prevalence, rate, significant and trend...
October 2015: Journal of Hand Surgery, European Volume
D F Hamilton, M Ghert, A H R W Simpson
No abstract text is available yet for this article.
September 2015: Bone & Joint Research
Thomas F Lüscher
No abstract text is available yet for this article.
September 21, 2015: European Heart Journal
R Libé, I Borget, C L Ronchi, B Zaggia, M Kroiss, T Kerkhofs, J Bertherat, M Volante, M Quinkler, O Chabre, M Bala, A Tabarin, F Beuschlein, D Vezzosi, T Deutschbein, F Borson-Chazot, I Hermsen, A Stell, C Fottner, S Leboulleux, S Hahner, M Mannelli, A Berruti, H Haak, M Terzolo, M Fassnacht, E Baudin
BACKGROUND: The clinical course of advanced adrenocortical carcinoma (ACC) is heterogeneous. Our study aimed primarily to refine and make headway in the prognostic stratification of advanced ACC. PATIENTS AND METHODS: Patients with advanced ENSAT ACC (stage III or stage IV) at diagnosis registered between 2000 and 2009 in the ENSAT database were enrolled. The primary end point was overall survival (OS). Parameters of potential prognostic relevance were selected...
October 2015: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Femke Simmer, Sabine Venderbosch, Jeroen R Dijkstra, Elisa M Vink-Börger, Claudius Faber, Leonie J Mekenkamp, Miriam Koopman, Anton F De Haan, Cornelis J Punt, Iris D Nagtegaal
Approximately half of the colorectal cancer (CRC) patients develop metastatic disease. Fluoropyrimidine-based chemotherapy forms the backbone of treatment in these patients. However, the response to this therapy varies between individuals. Therefore, an important challenge in CRC research is to identify biomarkers that are predictive of this response. In this study, we explored the potential of miRNAs, and the miRNA producing protein Dicer, as biomarkers that can predict chemo-sensitivity to fluoropyrimidine chemotherapy in patients with metastatic colorectal cancer (mCRC)...
September 8, 2015: Oncotarget
Mette Maria Skjøth, Helle Ploug Hansen, Eva Draborg, Claus Duedal Pedersen, Ronald F Lamont, Jan Stener Jørgensen
BACKGROUND: In Denmark, all pregnant women are offered screening in early pregnancy to estimate the risk of having a fetus with Down syndrome. Pregnant women participating in the screening program should be provided with information and support to allow them to make an informed choice. There is increasing interest in the use of Web-based technology to provide information and digital solutions for the delivery of health care. OBJECTIVE: The aim of this study was to develop an eHealth tool that contained accurate and relevant information to allow pregnant women to make an informed choice about whether to accept or reject participation in screening for Down syndrome...
2015: JMIR Research Protocols
M Müller-Eschner, M Dadrich, T Vogl, F Grünwald
No abstract text is available yet for this article.
2015: Nuklearmedizin. Nuclear Medicine
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