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Tracheal stenosis

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https://www.readbyqxmd.com/read/28921522/extraluminal-biodegradable-splint-to-treat-upper-airway-anterior-malacia-a-preclinical-proof-of-principle
#1
François Gorostidi, Cécile Courbon, Marco Burki, Antoine Reinhard, Kishore Sandu
OBJECTIVE: Upper airway malacia highly complicates the treatment of benign laryngotracheal stenosis, and no ideal option is available to date. We here explore the use of extraluminal biodegradable splints in an animal model of long-segment anterior tracheomalacia (TM). We show the efficacy, as well as the tissue tolerance, of a custom-made biodegradable extraluminal device surgically inserted around the trachea. STUDY DESIGN: Preclinical animal study. METHODS: Anterior TM was induced in rabbits through an anterior neck approach by removing eight consecutive anterior tracheal rings without damaging the underlying mucosa...
September 16, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28914829/-circular-tracheal-resection-for-cicatrical-stenosis-and-functioning-tracheostomy
#2
V D Parshin, V A Titov, V V Parshin, A V Parshin, Z Berikkhanov, D M Amangeldiev
AIM: To analyze the results of tracheal resection for cicatricial stenosis depending on the presence of tracheostomy. MATERIAL AND METHODS: 1128 patients with tracheal cicatricial stenosis were treated for the period 1963-2015. The first group consisted of 297 patients for the period 1963-2000, the second group - 831 patients for the period 2001-2015. Most of them 684 (60.6%) were young and able-bodied (age from 21 to 50 years). In the first group 139 (46.8%) out of 297 patients had functioning tracheostomy...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28904244/tracheobronchopathia-osteochondroplastica-in-recurrent-retrosternal-goiter-surgical-management
#3
Francesco Quaglino, Enrico Mazza, Mauro Navarra, Nicola Palestini, Valentina Marchese, Riccardo Lemini, Francesca Talarico, Emilpaolo Manno
Tracheobronchopathia osteochondroplastica (TPO) is a rare pathology characterized by a progressive segmentary stenosis of the respiratory tract due to proliferation of osteocartilagineous nodules in the lumen of the distal part of the trachea and large bronchial trunks. Prognosis is usually benign, but some cases with an acute progression and a lethal outcome have been described. Clinical presentation is non specific, the chest x-ray is generally normal and there are not typical radiological signs of suspicion: diagnosis of TPO is usually incidental...
September 4, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28888019/in-vivo-characterization-of-a-3d-hybrid-scaffold-based-on-pcl-decellularized-aorta-for-tracheal-tissue-engineering
#4
Fariba Ghorbani, Lida Moradi, Mohammad Behgam Shadmehr, Shahin Bonakdar, Atosa Droodinia, Farzaneh Safshekan
INTRODUCTION: As common treatments for long tracheal stenosis are associated with several limitations, tracheal tissue engineering is considered as an alternative treatment. AIM OF STUDY: This study aimed at preparing a hybrid scaffold, based on biologic and synthetic materials for tracheal tissue engineering. MATERIALS AND METHODS: Three electrospun polycaprolactone (PCL) scaffolds, namely E1 (pure PCL), E2 (collagen-coated PCL) and E3 (PCL blended with collagen) were prepared...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28882637/successful-retrograde-intubation-after-failed-fiberoptic-intubation-and-percutaneous-cricothyrotomy
#5
Stephanie Brenman, Sachin Gupta, Stephanie Tseeng
BACKGROUND: An obstructive neck lesion presents an airway challenge for any emergency physician. Retrograde intubation is an infrequently used airway alternative that can be employed in the difficult airway algorithm that requires little training and is less invasive than surgical cricothyrotomy. CASE REPORT: We report a case of a 31-year-old male patient who presented with respiratory distress progressing to respiratory failure from upper airway obstruction. The patient had significant tracheal thickening at the level of the thyroid gland based on a computed tomography report from 3 weeks prior to his presentation...
September 4, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28869225/resection-and-anastomosis-for-benign-tracheal-stenosis-single-institution-experience-of-18-cases
#6
Arvind Kumar, Belal Bin Asaf, Harsh Vardhan Puri, Amr Abdellateef
INTRODUCTION: Tracheal stenosis is a complex condition caused by altered inflammatory response to injury and subsequent excessive circumferential scar formation. Surgical resection, wherever possible, offers the best long-term results. Nonsurgical methods provide immediate relief to all can be curative in few but mostly serve as an excellent bridge to surgery in majority. The purpose of this study is to retrospectively evaluate the outcome following surgery for benign tracheal stenosis at our center...
September 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28857529/-surgical-treatment-of-tracheal-stenosis-a-11-year-report-in-a-pediatric-hospital
#7
M Boglione, A Reusmann, M Cadario, C Giuseppucci, H Botto, M Nieto, M Barrenechea
OBJECTIVES: To report our experience in the surgical treatment of patients having acquired and congenital tracheal stenosis. MATERIAL AND METHODS: Fifty eight patients with tracheal stenosis were surgically treated between July 2005 and May 2016, 29 were females and 29 were males. Thirty patients had acquired stenosis and 28 had congenital stenosis. RESULTS: Five to 12 rings were resected (median 5) in 26 patients, in 2 cartilage was grafted in the anterior wall, in another carinostomy was performed, and in the remaining, the trachea was replaced using an aortic cryopreserved graft...
April 20, 2017: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28814580/ventrain-from-theory-to-practice-bridging-until-re-tracheostomy
#8
Bianca Maria Wahlen, Hassan Al-Thani, Ayman El-Menyar
Imminent upper airway obstruction due to life-threatening tracheal stenosis of any cause is challenging. A 77-year-old woman, with a history of temporal tracheostomy for prolonged mechanical ventilation, presented with life-threatening tracheal stenosis to the emergency department. After failed intubation with a 5.0 mm internal diameter endotracheal tube, the patient was ventilated via a tube exchanger using Ventrain. Ventrain is a manual ventilation device that, in addition to oxygen supply during inspiration, initiates expiration by actively removing gas from the lungs by suction...
August 16, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28801794/management-of-congenital-tracheal-stenosis-in-the-neonatal-period
#9
Keiichi Morita, Kosaku Maeda, Kiyoaki Yabe, Yoshihiro Oshima
PURPOSE: Few reports have focused on the management of congenital tracheal stenosis (CTS) in the neonatal period. The aim of this study was to determine appropriate management strategies for CTS in the neonatal period. METHODS: The medical records of eight neonatal patients with CTS at a single institution between January 2007 and December 2016 were retrospectively reviewed. RESULTS: Three patients with frequent ventilatory insufficiency despite assisted ventilation underwent surgical intervention (balloon tracheoplasty: n = 1, slide tracheoplasty: n = 2)...
August 11, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28794964/innovative-use-of-a-montgomery-cannula-in-the-bronchoscopic-management-of-tracheal-stenosis-and-failed-tracheostomy-decannulation
#10
Haidong Huang, Changming Chen, Harmeet Bedi, Chong Bai, Qiang Li, Wolfgang Hohenforst-Schmidt, Paul Zarogoulidis
BACKGROUND: Endoprosthesis are being used in the everyday clinical practice either as a permanent solution or transient. They can be used in both benign and malignant situations. CASE PRESENTATION: We report a case in which a temporary Montgomery cannula is used in conjunction with therapeutic bronchoscopy to manage a patient with failed tracheostomy decannulation secondary to a distal complex tracheal stenosis. CONCLUSIONS: This innovative use of the Montgomery cannula allowed for successful management of the patient's tracheal stenosis and subsequent tracheostomy tube decannulation...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28793902/30-year-experience-of-fontan-surgery-single-centre-s-data
#11
Laurynas Bezuska, Virgilijus Lebetkevicius, Rita Sudikiene, Daina Liekiene, Virgilijus Tarutis
BACKGROUND: The Fontan procedure has been modified several times since it was introduced into practice in 1968. As many patients now survive to adulthood, attention is directed towards their clinical status and late morbidity. We report our surgical experience of 30 years in Fontan procedures. METHODS: From January 1985 to January 2015, 80 patients underwent Fontan surgery. Twenty-one patients received an atrio-pulmonary Fontan (Group I), four patients underwent total cavopulmonary connection (TCPC) with an intra-atrial lateral tunnel (Group II), six patients received extra-cardiac TCPC with an aortic homograft (group III) and 49 patients received extra-cardiac TCPC with an expanded polytetrafluoroethylene conduit...
August 9, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28776693/a-comparison-of-tracheal-scaffold-strategies-for-pediatric-transplantation-in-a-rabbit-model
#12
Elizabeth F Maughan, Colin R Butler, Claire Crowley, Gui Zhen Teoh, Margot Den Hondt, Nicholas J Hamilton, Robert E Hynds, Peggy Lange, Tahera Ansari, Luca Urbani, Samuel M Janes, Paolo De Coppi, Martin A Birchall, Martin J Elliott
OBJECTIVES/HYPOTHESIS: Despite surgical advances, childhood tracheal stenosis is associated with high morbidity and mortality. Various tracheal scaffold strategies have been developed as the basis for bioengineered substitutes, but there is no consensus on which may be superior in vivo. We hypothesized that there would be no difference in morbidity and mortality between three competing scaffold strategies in rabbits. STUDY DESIGN: Pilot preclinical study. METHODS: Tracheal scaffolds were prepared by three methods that have been applied clinically and reported: preserved cadaveric ("Herberhold") allografts, detergent-enzymatically decellularized allografts, and synthetic scaffolds (nanocomposite polymer [polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU)])...
August 4, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28768272/comparison-between-primary-and-secondary-tracheoesophageal-puncture-prosthesis-a-systematic-review
#13
José Carlos Barauna Neto, Rogério Aparecido Dedivitis, Felipe Toyama Aires, Robert Zasawadzki Pfann, Leandro Luongo Matos, Claudio Roberto Cernea
INTRODUCTION: Since the introduction of tracheoesophageal puncture (TEP) and placement of voice prosthesis, this has become the method of choice to achieve speech rehabilitation after total laryngectomy. OBJECTIVE: To compare the complications and success in speech rehabilitation of patients undergoing rehabilitation after primary and secondary TEP (TEP1 and TEP2) through a systematic review. METHODS: The literature survey included research in MedLine, Scielo, Lilacs, Cochrane and Websco until June 2016...
2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28747947/a-foreign-body-mimicking-tracheal-stenosis
#14
Ahmet Sizlanan, Onur Akcay
No abstract text is available yet for this article.
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28736614/tracheal-granuloma-7-years-after-extubation
#15
Kazuhisa Nakashima, Tateaki Naito, Masahiro Endo, Takashi Nakajima, Toshiaki Takahashi
Tracheal granuloma can cause severe stenosis long after extubation. When a patient with a history of endobronchial intubation has an intratracheal tumour, we should consider the possibility of this condition.
September 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28731623/concentric-photothermal-coagulation-with-basket-integrated-optical-device-for-treatment-of-tracheal-stenosis
#16
Van Nam Tran, Hyungshin Lee, Van Gia Truong, Yun-Hee Rhee, Hyun Wook Kang
A basket-integrated optical device is developed to consistently treat tubular tissue by centering an optical diffuser in the lumen. Four nitinol arms in conjunction with the optical diffusing applicator are deployed to induce homogeneous circumferential light emission and concentric photothermal coagulation on tracheal tissue. 1470-nm laser light is employed for the tissue testing at various irradiation conditions and evaluated in terms of thermal gradient and temperature evolution. Preliminary experiments on liver tissue demonstrate the concentric development of the radial thermal coagulation in the tissue (eccentric ratio = ~5...
July 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28715559/interferon-%C3%AE-treatment-of-human-laryngotracheal-stenosis-derived-fibroblasts
#17
Kevin Motz, Idris Samad, Linda X Yin, Michael K Murphy, Madhavi Duvvuri, Dacheng Ding, Alexander T Hillel
Importance: Laryngotracheal stenosis (LTS) is a fibroproliferative disorder of the glottis, subglottis, and trachea. In models of fibrosis from other organ systems, the CD4+ T-cell response has been shown to regulate extracellular matrix deposition. Specifically, helper T cell 2 (TH2) promotes fibrosis, whereas TH1 and associated cytokines have been shown to be antifibrotic. However, this antifibrotic effect of the TH1 response has not been demonstrated in LTS. Objective: To determine whether the TH1 cytokine interferon-γ inhibits the function of LTS-derived fibroblasts in vitro...
July 13, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28701742/tissue-engineered-trachea-from-a-3d-printed-scaffold-enhances-whole-segment-tracheal-repair
#18
Manchen Gao, Hengyi Zhang, Wei Dong, Jie Bai, Botao Gao, Dekai Xia, Bei Feng, Maolin Chen, Xiaomin He, Meng Yin, Zhiwei Xu, Nevin Witman, Wei Fu, Jinghao Zheng
Long segmental repair of trachea stenosis is an intractable condition in the clinic. The reconstruction of an artificial substitute by tissue engineering is a promising approach to solve this unmet clinical need. 3D printing technology provides an infinite possibility for engineering a trachea. Here, we 3D printed a biodegradable reticular polycaprolactone (PCL) scaffold with similar morphology to the whole segment of rabbits' native trachea. The 3D-printed scaffold was suspended in culture with chondrocytes for 2 (Group I) or 4 (Group II) weeks, respectively...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28701608/management-of-a-case-of-double-aortic-arch-with-tracheal-compression-complicated-with-postoperative-tracheal-restenosis
#19
Hemang Gandhi, T Vikram Kumar Naidu, Amit Mishra, Pankaj Garg, Jigar Surti, Visharad Trivedi, Himanshu Acharya
Tracheal stenosis in association with the double aortic arch (DAA) is uncommon; however, it carries a high risk of morbidity, mortality, and restenosis. Although surgery is the mainstay of managing a case of the DAA with tracheal stenosis, management of tracheal restenosis requires a multidisciplinary approach. In this case report, we present our successful experience in managing a child of DAA with tracheal stenosis who developed tracheal restenosis after sliding tracheoplasty of trachea.
July 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28701606/silicone-tracheobronchial-stent-a-rare-cause-for-bronchoesophageal-fistula-and-distortion-of-airway-anatomy
#20
Bhupesh Kumar, Ganesh Kumar Munirathinam, Goverdhan Dutt Puri, Anand Kumar Mishra, Virendra Kumar Arya
Silicone tracheobronchial stents are being increasingly used in a large number of patients for the treatment of tracheal stenosis. One very rare complication due to tracheobronchial stenting is bronchoesophageal fistula (BEF), which has been associated with the use of metallic stents. We report intraoperative management of a patient undergoing repair of a BEF, following previous insertion of a silicone Y-stent that is soft in texture and has not been implicated for this complication till date. In addition, misalignment of this silicone tracheobronchial Y-stent resulted in a tracheal mucosal bulge proximal to the stent that vanished after its removal...
July 2017: Annals of Cardiac Anaesthesia
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