keyword
MENU ▼
Read by QxMD icon Read
search

Hailey hailey disease

keyword
https://www.readbyqxmd.com/read/29725648/nephcure-accelerating-cures-institute-a-multidisciplinary-consortium-to-improve-care-for-nephrotic-syndrome
#1
Debbie S Gipson, David T Selewski, Susan F Massengill, Mary Margaret Modes, Hailey Desmond, Lauren Lee, Elaine Kamil, Matthew R Elliott, Sharon G Adler, Gia Oh, Richard A Lafayette, Patrick E Gipson, Aditi Sinha, Arvind Bagga, Anne Pesenson, Cheryl Courtlandt, Cathie Spino, Richard Eikstadt, Renée Pitter, Samara Attalla, Anne Waldo, Richard Winneker, Noelle E Carlozzi, Jonathan P Troost, Irving Smokler, Mark Stone
Introduction: NephCure Accelerating Cures Institute (NACI) is a collaborative organization sponsored by NephCure Kidney International and the University of Michigan. The Institute is composed of 7 cores designed to improve treatment options and outcomes for patients with glomerular disease: Clinical Trials Network, Data Warehouse, Patient-Reported Outcomes (PRO) and Endpoints Consortium, Clinical Trials Consulting Team, Quality Initiatives, Education and Engagement, and Data Coordinating Center...
March 2018: KI Reports
https://www.readbyqxmd.com/read/29705999/mild-hailey-hailey-disease-cases-with-aberrant-splicing-variants-of-atp2c1-successfully-controlled-with-excimer-light
#2
M Kono, M Niizawa, T Takeichi, Y Muro, M Akiyama
A 79-year-old Japanese male (Case 1) had had repetitive erosions on the neck and trunk every summer for 13 years (Fig. 1a). A 69-year-old Japanese female (Case 2) had had recurrent erosions on the axillae, the inframammary areas and the groin every summer since her early sixties (Fig. 1d). The lesions of both patients revealed acantholysis and dyskeratosis in the epidermis (Fig. 1c, f). Neither patient had any family history of similar skin disorders. This article is protected by copyright. All rights reserved...
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29644210/dermoscopy-of-hailey-hailey-disease
#3
Payal Chauhan, Dilip Meena, Neirita Hazarika
No abstract text is available yet for this article.
March 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29594415/restricted-mhc-class-i-a-locus-diversity-in-olive-and-hybrid-olive-yellow-baboons-from-the-southwest-national-primate-research-center
#4
Rebecca A Morgan, Julie A Karl, Hailey E Bussan, Katelyn E Heimbruch, David H O'Connor, Dawn M Dudley
Baboons are valuable models for complex human diseases due to their genetic and physiologic similarities to humans. Deep sequencing methods to characterize full-length major histocompatibility complex (MHC) class I (MHC-I) alleles in different nonhuman primate populations were used to identify novel MHC-I alleles in baboons. We combined data from Illumina MiSeq sequencing and Roche/454 sequencing to characterize novel full-length MHC-I transcripts in a cohort of olive and hybrid olive/yellow baboons from the Southwest National Primate Research Center (SNPRC)...
March 28, 2018: Immunogenetics
https://www.readbyqxmd.com/read/29555205/store-independent-coupling-between-the-secretory-pathway-ca-2-transport-atpase-spca1-and-orai1-in-golgi-stress-and-hailey-hailey-disease
#5
Susanne Smaardijk, Jialin Chen, Sara Kerselaers, Thomas Voets, Jan Eggermont, Peter Vangheluwe
The Secretory Pathway Ca2+ ATPases SPCA1 and SPCA2 transport Ca2+ and Mn2+ into the Golgi and Secretory Pathway. SPCA2 mediates store-independent Ca2+ entry (SICE) via STIM1-independent activation of Orai1, inducing constitutive Ca2+ influx in mammary epithelial cells during lactation. Here, we show that like SPCA2, also the overexpression of the ubiquitous SPCA1 induces cytosolic Ca2+ influx, which is abolished by Orai1 knockdown and occurs independently of STIM1. This process elevates the Ca2+ concentration in the cytosol and in the non-endoplasmic reticulum (ER) stores, pointing to a functional coupling between Orai1 and SPCA1...
March 16, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29538692/outpatient-clinic-visits-during-heat-waves-findings-from-a-large-family-medicine-clinical-database
#6
Devesh Vashishtha, William Sieber, Brittany Hailey, Kristen Guirguis, Alexander Gershunov, Wael K Al-Delaimy
Introduction: The purpose of this study was to determine whether heat waves are associated with increased frequency of clinic visits for ICD-9 codes of illnesses traditionally associated with heat waves. Methods: During 4 years of family medicine clinic data between 2012 and 2016, we identified six heat wave events in San Diego County. For each heat wave event, we selected a control period in the same season that was twice as long. Scheduling a visit on a heat wave day (versus a non-heat wave day) was the primary predictor, and receiving a primary ICD-9 disease code related to heat waves was the outcome...
March 10, 2018: Family Practice
https://www.readbyqxmd.com/read/29496987/-18-f-xtra-pet-for-enhanced-imaging-of-the-extrathalamic-%C3%AE-4%C3%AE-2-nicotinic-acetylcholine-receptor
#7
Jennifer Marie Coughlin, Stephanie Slania, Yong Du, Hailey B Rosenthal, Wojciech G Lesniak, Il Minn, Gwenn S Smith, Robert F Dannals, Hiroto Kuwabara, Dean F Wong, Yuchuan Wang, Andrew G Horti, Martin G Pomper
Reduced density of the α4β2 nicotinic acetylcholine receptor (α4β2-nAChR) in the cortex and hippocampus of human brain has been reported in aging and patients with neurodegenerative disease. This study assessed the pharmacokinetic behavior of 18 F-XTRA, a new radiotracer for in vivo positron emission tomography (PET) imaging of the α4β2-nAChR, particularly in extrathalamic regions of interest (ROIs) where the α4β2-nAChR is less densely expressed than in thalamus. 18 F-XTRA was also used to evaluate the α4β2-nAChR in hippocampus in human aging...
March 1, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29470861/mini-cog-for-the-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-within-a-primary-care-setting
#8
REVIEW
Dallas P Seitz, Calvin Ch Chan, Hailey T Newton, Sudeep S Gill, Nathan Herrmann, Nadja Smailagic, Vasilis Nikolaou, Bruce A Fage
BACKGROUND: Alzheimer's disease and other forms of dementia are becoming increasingly common with the aging of most populations. The majority of individuals with dementia will first present for care and assessment in primary care settings. There is a need for brief dementia screening instruments that can accurately diagnose dementia in primary care settings. The Mini-Cog is a brief, cognitive screening test that is frequently used to evaluate cognition in older adults in various settings...
February 22, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29468291/lymphangiomatosis-a-rare-entity-presenting-with-involvement-of-the-sacral-plexus
#9
Megan K Mills, Bryn Putbrese, Hailey Allen, Sarah E Stilwill
Lymphangiomatosis is an uncommon disease process characterized by multisystem lymphatic malformations that can involve numerous body systems, including organs, muscles, soft tissues, and bones. Involvement of the nervous system is rare and has even been previously described as a site of sparing. We present a case of a 24-year-old female with known lymphangiomatosis, presenting with acute onset of lower extremity paresthesias, weakness, and new urinary retention. MRI of the pelvis revealed lymphangiomatosis of the sacral plexus, which has not been previously reported...
February 21, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29467079/narrowband-uv-b-phototherapy-in-the-treatment-of-generalized-hailey-hailey-disease
#10
M C Abaca, L Flores, V Parra
No abstract text is available yet for this article.
February 18, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29446546/de-novo-variants-in-myelin-regulatory-factor-myrf-as-candidates-of-a-new-syndrome-of-cardiac-and-urogenital-anomalies
#11
Hailey Pinz, Louise C Pyle, Dong Li, Kosuke Izumi, Cara Skraban, Jennifer Tarpinian, Stephen R Braddock, Aida Telegrafi, Kristin G Monaghan, Elaine Zackai, Elizabeth J Bhoj
Myelin Regulatory Factor (MYRF) is a transcription factor that has previously been associated with the control of the expression of myelin-related genes. However, it is highly expressed in human tissues and mouse embryonic tissues outside the nervous system such as the stomach, lung, and small intestine. It has not previously been reported as a cause of any Mendelian disease. We report here two males with Scimitar syndrome [MIM 106700], and other features including penoscrotal hypospadias, cryptorchidism, pulmonary hypoplasia, tracheal anomalies, congenital diaphragmatic hernia, cleft spleen, thymic involution, and thyroid fibrosis...
April 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29445030/cabozantinib-in-patients-with-advanced-merkel-cell-carcinoma
#12
Guilherme Rabinowits, Cecilia Lezcano, Paul J Catalano, Patricia McHugh, Hailey Becker, Megan M Reilly, Julian Huang, Ayushi Tyagi, Manisha Thakuria, Scott C Bresler, Lynette M Sholl, Geoffrey I Shapiro, Robert Haddad, James A DeCaprio
BACKGROUND: This study sought to determine the efficacy and safety profile of cabozantinib in patients with advanced Merkel cell carcinoma (MCC). EXPERIMENTAL DESIGN: This prospective, phase II, single-institution trial enrolled patients with platinum-failure, recurrent/metastatic MCC to receive cabozantinib 60 mg orally daily until disease progression, withdrawal from study, or severe toxicity. The primary endpoint was disease control rate. Secondary endpoints included overall survival (OS), progression-free survival (PFS), and toxicity...
February 14, 2018: Oncologist
https://www.readbyqxmd.com/read/29440034/subclinical-compromise-in-cardiac-strain-relates-to-lower-cognitive-performances-in-older-adults
#13
Hailey A Kresge, Omair A Khan, Madison A Wagener, Dandan Liu, James G Terry, Sangeeta Nair, Francis E Cambronero, Katherine A Gifford, Katie E Osborn, Timothy J Hohman, Kimberly R Pechman, Susan P Bell, Thomas J Wang, John Jeffrey Carr, Angela L Jefferson
BACKGROUND: Global longitudinal strain (GLS), reflecting total shortening of the myocardium during the cardiac cycle, has emerged as a more precise myocardial function measure than left ventricular ejection fraction (LVEF). Longitudinal strain may be selectively affected in subclinical heart disease, even in the presence of normal LVEF. This study examines subclinical cardiac dysfunction, assessed by GLS and LVEF, and cognition among older adults. METHODS AND RESULTS: Vanderbilt Memory and Aging Project participants who were free of clinical dementia, stroke, and heart failure (n=318, 73±7 years, 58% male) completed neuropsychological assessment and cardiac magnetic resonance to quantify GLS and LVEF...
February 13, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29426802/development-of-mycoplasma-pneumoniae-biofilms-in-vitro-and-the-limited-role-of-motility
#14
Monica Feng, Andrew C Schaff, Sara A Cuadra Aruguete, Hailey E Riggs, Steven L Distelhorst, Mitchell F Balish
Mycoplasma pneumoniae is a bacterial pathogen of humans that is a major causative agent of chronic respiratory disease. M. pneumoniae infections often recur even after successful treatment of symptoms with antibiotics, and resistance to antibiotics is increasing worldwide, with nearly complete resistance in some places. Although biofilms often contribute to chronicity and resistance, M. pneumoniae biofilms remain poorly characterized. Scanning electron microscopy revealed that cells of wild-type (WT) M. pneumoniae strain M129 biofilms, as well as mutants II-3 and II-3R, in vitro became increasingly rounded as the biofilm towers matured over 5 days...
April 2018: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29420051/loss-of-cdkn2b-promotes-fibrosis-via-increased-fibroblast-differentiation-rather-than-proliferation
#15
Anne M Scruggs, Hailey B Koh, Priya Tripathi, Nicholas J Leeper, Eric S White, Steven K Huang
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease characterized by excessive scarring and fibroblast activation. We previously showed that fibroblasts from patients with IPF are hypermethylated at the CDKN2B gene locus resulting in decreased CDKN2B expression. Here, we examine how diminished CDKN2B expression in normal and IPF fibroblasts affect fibroblast function and how loss of CDKN2B contributes to IPF pathogenesis. We first confirmed that protein expression of CDKN2B was diminished in IPF lungs in situ...
February 8, 2018: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/29396807/the-cns-penetrating-taxane-tpi-287-and-the-aurka-inhibitor-alisertib-induce-synergistic-apoptosis-in-glioblastoma-cells
#16
Cory T Zumbar, Aisulu Usubalieva, Paul D King, Xiaohui Li, Caroline S Mifsud, Hailey M Dalton, Muge Sak, Sara Urio, William M Bryant, Joseph P McElroy, George Farmer, Norman L Lehman
Glioblastoma is a highly malignant disease in critical need of expanded treatment options. The AURKA inhibitor alisertib exhibits antiproliferative activity against glioblastoma in vitro and in vivo. Unlike current clinically used taxane drugs, the novel taxane TPI 287 penetrates the CNS. We tested for interactions between three selective AURKA inhibitors and TPI 287 against standard U87 and U1242 cells and primary glioblastoma neurospheres using colony formation assays. Bliss and Chou-Talalay analyses were utilized to statistically test for synergism...
May 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29381840/swimming-against-the-current-a-qualitative-review-of-the-work-experiences-and-adaptations-made-by-employees-with-arthritis
#17
R J Purc-Stephenson, Jessica Dostie, Hailey J Smith
OBJECTIVE: To describe the experiences and strategies of employees with arthritis (EwA) to maintain employment and to use this information to build a conceptual model. METHODS: We conducted a systematic review of qualitative studies that examined the work experiences of EwA. Published studies on arthritis and employment were searched from electronic databases (1980-2017) and bibliographical reviews of relevant studies. We used meta-ethnography to synthesize the findings...
January 30, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29374028/paediatric-obesity-appears-to-lower-the-risk-of-diabetes-if-selection-bias-is-ignored
#18
Steven D Stovitz, Hailey R Banack, Jay S Kaufman
BACKGROUND: Frustrated with the onslaught of articles reporting fascination with results that appear paradoxical but are merely due to selection bias, we studied the apparent effect of obesity on diabetes risk in youth who had a test for diabetes. We hypothesised that obese subjects would have lower rates of diabetes than non-obese subjects due to selection bias, and consequently, obesity would appear to lower the risk of diabetes. METHODS: Retrospective cohort study of children (4-9 years), pre-teens (10-12 years) and teenagers (13-19 years)...
April 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29344611/variable-response-to-naltrexone-in-patients-with-hailey-hailey-disease
#19
Severine Cao, Evelyn Lilly, Steven T Chen
No abstract text is available yet for this article.
March 1, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29289401/structural-bias-in-studies-of-cardiovascular-disease-let-s-not-be-fooled-by-the-obesity-paradox
#20
EDITORIAL
Steven D Stovitz, Hailey R Banack, Jay S Kaufman
No abstract text is available yet for this article.
May 2018: Canadian Journal of Cardiology
keyword
keyword
20790
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"