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https://www.readbyqxmd.com/read/28549332/synthesis-and-characterization-of-fullerene-modified-znalti-ldo-in-photo-degradation-of-bisphenol-a-under-simulated-visible-light-irradiation
#1
Liting Ju, Pingxiao Wu, Xiaolin Lai, Shanshan Yang, Beini Gong, Meiqing Chen, Nengwu Zhu
In this study, ZnAlTi layered double hydroxide (ZnAlTi-LDH) combined with fullerene (C60) was fabricated by the urea method, and calcined under vacuum atmosphere to obtain nanocomposites of C60-modified ZnAlTi layered double oxide (ZnAlTi-LDO). The morphology, structure and composition of the nanocomposites were analyzed by Scanning Electron Microscopy, High-resolution transmission electron microscopy, X-ray diffraction patterns, Fourier transform infrared and specific surface area. The UV-vis diffuse reflectance spectra indicated that the incorporation of C60 expanded the absorption of ZnAlTi-LDO to visible-light region...
May 23, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28549143/bile-acids-and-tryptophan-metabolism-are-novel-pathways-involved-in-metabolic-abnormalities-in-bpa-exposed-pregnant-mice-and-male-offspring
#2
Martha Susiarjo, Frances Xin, Martha Stefaniak, Clementina Mesaros, Rebecca A Simmons, Marisa S Bartolomei
Increasing evidence has demonstrated that exposure to endocrine disrupting chemicals (EDCs) impacts maternal and fetal health, but the underlying mechanisms are still unclear. We have previously shown that dietary exposure to 10 µg/kg bw/day and 10 mg/kg bw/day bisphenol A (BPA) during pregnancy induced metabolic abnormalities in F1 male offspring and gestational glucose intolerance in F0 pregnant mice. The aim of this study is to elucidate the underlying etiologies of BPA exposure-induced metabolic disease by analyzing male fetal liver metabolome...
May 25, 2017: Endocrinology
https://www.readbyqxmd.com/read/28548952/bisphenol-a-exposure-promotes-htr-8-svneo-cell-migration-and-impairs-mouse-placentation-involving-upregulation-of-integrin-%C3%AE-1-and-mmp-9-and-stimulation-of-mapk-and-pi3k-signaling-pathways
#3
Xi Lan, Li-Juan Fu, Jun Zhang, Xue-Qing Liu, Hui-Jie Zhang, Xue Zhang, Ming-Fu Ma, Xue-Mei Chen, Jun-Lin He, Lian-Bing Li, Ying-Xiong Wang, Yu-Bin Ding
In this study, we investigated the effect of Bisphenol A (BPA), an endocrine-disrupting chemical, on the migration of human trophoblasts and mouse placentation by using the primary extravillous trophoblast (EVT) and its cell line HTR-8/SVneo, villous explant cultures, and pregnant mice. BPA increased EVT motility and the outgrowth of villous explants in a dose-dependent manner. BPA also increased the protein levels of integrin-β1 and matrix metalloproteinase (MMP)-9 in human EVTs. Low-dose BPA (≤50 mg) increased the protein levels of MMP-9 and MMP-2 as well as integrin-β1 and integrin-α5 in mouse placenta and decreased the proportion of the labyrinth and spongiotrophoblast layers...
May 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28545000/occurrence-and-effects-of-plastic-additives-on-marine-environments-and-organisms-a-review
#4
REVIEW
Ludovic Hermabessiere, Alexandre Dehaut, Ika Paul-Pont, Camille Lacroix, Ronan Jezequel, Philippe Soudant, Guillaume Duflos
Plastics debris, especially microplastics, have been found worldwide in all marine compartments. Much research has been carried out on adsorbed pollutants on plastic pieces and hydrophobic organic compounds (HOC) associated with microplastics. However, only a few studies have focused on plastic additives. These chemicals are incorporated into plastics from which they can leach out as most of them are not chemically bound. As a consequence of plastic accumulation and fragmentation in oceans, plastic additives could represent an increasing ecotoxicological risk for marine organisms...
May 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28543135/bone-mineral-density-testing-and-bisphosphonate-and-oestrogen-prescribing-associated-with-depot-medroxyprogesterone-acetate-utilization-the-impact-of%C3%A2-the%C3%A2-boxed-warning
#5
E Eworuke, V Popat, D G Moeny
WHAT IS KNOWN AND OBJECTIVE: Depot medroxyprogesterone acetate (DMPA) prevents follicular maturation and ovulation, resulting in oestrogen deficiency. Oestrogen deficiency is particularly concerning as it is associated with decreases in bone mineral density (BMD) or bone mass. Widespread use of concurrent oestrogen or bisphosphonates with DMPA has been observed in a previous single-centre US study. The authors also reported that more than half of obstetrician-gynaecologists ordered BMD testing solely due to DMPA...
May 23, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28536853/simultaneous-production-of-laccase-and-degradation-of-bisphenol-a-with-trametes-versicolor-cultivated-on-agricultural-wastes
#6
Shengquan Zeng, Jie Zhao, Liming Xia
Solid state fermentation with Trametes versicolor was carried out on agricultural wastes containing bisphenol A (BPA). It was found that BPA degradation was along with the occurrence of laccase production, and wheat bran and corn straw were identified as suitable mixed substrates for laccase production. In the process of BPA degradation with T. versicolor, laccase activity increased rapidly at the 6th-10th day after inoculation. Moreover, BPA can enhance the production of laccase. After 10 days of fermentation, degradation rate of BPA exceeded 90% without the usage of mediators ABTS and acetosyringone at pH 4...
May 23, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/28535862/effects-of-water-bottle-materials-and-filtration-on-bisphenol-a-content-in-laboratory-animal-drinking-water
#7
Jennifer A Honeycutt, Jenny Q T Nguyen, Amanda C Kentner, Heather C Brenhouse
Bisphenol A (BPA) is widely used in the polycarbonate plastics and epoxy resins that are found in laboratory animal husbandry materials including cages and water bottles. Concerns about BPA exposure in humans has led to investigations that suggest physiologic health risks including disruptions to the endocrine system and CNS. However, the extent of exposure of laboratory animals to BPA in drinking water is unclear. In the first study, we compared the amount of BPA contamination in water stored in plastic bottles used in research settings with that in glass bottles...
May 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28535429/high-speed-video-analysis-of-forward-and-backward-spattered-blood-droplets
#8
P M Comiskey, A L Yarin, D Attinger
High-speed videos of blood spatter due to a gunshot taken by the Ames Laboratory Midwest Forensics Resource Center (MFRC) [1] are analyzed. The videos used in this analysis were focused on a variety of targets hit by a bullet which caused either forward, backward, or both types of blood spatter. The analysis process utilized particle image velocimetry (PIV) and particle analysis software to measure drop velocities as well as the distributions of the number of droplets and their respective side view area. The results of this analysis revealed that the maximal velocity in the forward spatter can be about 47±5m/s and for the backward spatter - about 24±8m/s...
May 1, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28529144/toxicant-induced-behavioural-aberrations-in-larval-zebrafish-are-dependent-on-minor-methodological-alterations
#9
Thomas W K Fraser, Abdolrahman Khezri, Juan G H Jusdado, Anna M Lewandowska-Sabat, Theodore Henry, Erik Ropstad
Alterations in zebrafish motility are used to identify neurotoxic compounds, but few have reported how methodology may affect results. To investigate this, we exposed embryos to bisphenol A (BPA) or tetrabromobisphenol A (TBBPA) before assessing larval motility. Embryos were maintained on a day/night cycle (DN) or in constant darkness, were reared in 96 or 24 well plates (BPA only), and behavioural tests were carried out at 96, 100, or 118 (BPA only) hours post fertilisation (hpf). We found that the prior photo-regime, larval age, and/or arena size influence behavioural outcomes in response to toxicant exposure...
May 18, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28528315/bisphenol-a-and-replacements-in-thermal-paper-a-review
#10
REVIEW
Maria K Björnsdotter, Jacob de Boer, Ana Ballesteros-Gómez
Thermal paper contains potentially toxic compounds such as bisphenol A (BPA), which is used as a color developer. BPA has been reported in thermal paper in concentrations up to 42,600 μg g(-1). The exposure to BPA via dermal transfer has been recently discussed as a significant contribution to the overall human exposure and the estimated daily intake (EDI) has been reported up to 218 μg d(-1). BPA has been also detected in recycled paper with concentrations up to 46 μg g(-1). Due to the fact that BPA is a known endocrine disruptor and migrates from materials, regulatory restrictions have been established to prevent risks for the human health...
May 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28526030/prenatal-bisphenol-a-exposure-and-dysregulation-of-infant-hypothalamic-pituitary-adrenal-axis-function-findings-from-the-apron-cohort-study
#11
Gerald F Giesbrecht, Maede Ejaredar, Jiaying Liu, Jenna Thomas, Nicole Letourneau, Tavis Campbell, Jonathan W Martin, Deborah Dewey
BACKGROUND: Animal models show that prenatal bisphenol A (BPA) exposure leads to sexually dimorphic disruption of the neuroendocrine system in offspring, including the hypothalamic-pituitary-adrenal (HPA) neuroendocrine system, but human data are lacking. In humans, prenatal BPA exposure is associated with sex-specific behavioural problems in children, and HPA axis dysregulation may be a biological mechanism. The objective of the current study was to examine sex differences in associations between prenatal maternal urinary BPA concentration and HPA axis function in 3 month old infants...
May 19, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28521687/diet-and-contaminants-driving-the-rise-to-obesity-epidemics
#12
Agostino Di Ciaula, Piero Portincasa
The obesity epidemic is spreading worldwide without reversal trend and despite specific policies oriented to dietary habits and lifestyle, which seem to have modest effects. Genetic factors only partly explain the rise, whereas environmental factors seem to play a key role, mainly by gene-environment interactions through epigenetic mechanisms. A number of animal and human studies point to maternal diet, intestinal microbiota and chemicals introduced as contaminants with food, all factors able to increase the risk of obesity...
May 17, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28521190/simultaneous-determination-of-bisphenol-a-and-estrogens-in-hair-samples-by-liquid-chromatography-electrospray-tandem-mass-spectrometry
#13
Chaelin Lee, Chong Hyeak Kim, Sunghwan Kim, Sung-Hee Cho
Bisphenol A (BPA), an endocrine disrupter, is widely used to make chemicals for polycarbonate, plastics, beverage containers, epoxy resins, and cash register receipts. BPA is one of the known xenoestrogens, which have weak estrogenic activity and cause obesity, diabetes, breast cancer, and reproductive disorders. Even though the concentration level of metabolomes in hair is usually lower than that in urine and blood, there are several reasons why we chose to use hair samples. First, the sampling procedure of hairs is simple...
May 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28521160/evidence-for-bisphenol-a-induced-disruption-of-maternal-thyroid-homeostasis-in-the-pregnant-ewe-at-low-level-representative-of-human-exposure
#14
Davy Guignard, Véronique Gayrard, Marlène Z Lacroix, Sylvie Puel, Nicole Picard-Hagen, Catherine Viguié
Many uncertainties remain regarding the potential of bisphenol A (BPA) as a thyroid disruptor in mammals and the relevance of experimental data to humans. The relevance of the exposure schemes used in experimental in vivo studies is also a major source of uncertainty when analysing the risk of BPA exposure for human health. In this context, the goals of our study, conducted in an ovine model relevant to human gestation and thyroid physiologies, were to: 1) determine the equivalence of subcutaneous and dietary exposures and 2) determine if environmentally relevant doses of BPA can alter gestational and newborn thyroid functions...
May 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28516806/is-bisphenol-a-exposure-associated-with-the-development-of-glucose-intolerance-and-increased-insulin-resistance-in-thais
#15
La-Or Chailurkit, Pechngam Tengpraettanakorn, Suwannee Chanprasertyotin, Boonsong Ongphiphadhanakul
Bisphenol A (BPA), the monomeric component of polycarbonate plastics, reportedly possesses endocrine-disrupting effects. Exposure to low levels of BPA during more vulnerable periods leads to abnormalities related to sexual development in experimental animals. Moreover, recently a few epidemiological studies in Caucasians have demonstrated the association of BPA exposure with type 2 diabetes. Therefore, in the present study we examined the association of BPA exposure and abnormal glucose tolerance in Thais. This is a cross-sectional study of 240 participants aged at least 50 years, randomly selected by computer-generated random numbers within each glucose tolerance status from an oral glucose tolerance study of 661 participants...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28512708/titanium-dioxide-based-sonophotocatalytic-mineralization-of-bisphenol-a-and-its-intermediates
#16
Sharmini Sunasee, Kien Tiek Wong, Gooyong Lee, Saravanan Pichiah, Shaliza Ibrahim, Chulhwan Park, Nam Chan Kim, Yeomin Yoon, Min Jang
In this study, bisphenol A (BPA) removal by sonophotocatalysis coupled with commercially available titanium dioxide (TiO2, P25) was assessed in batch tests using energy-based advanced oxidation combining ultrasound (US) and ultraviolet (UV). The kinetics of BPA removal were systematically evaluated by changing operational parameters, such as US frequency and power, mechanical stirring speed, and temperature, but also comparison of single and coupled systems under the optimum US conditions (35 kHz, 50 W, 300 rpm stirring speed, and 20 °C)...
May 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28511354/occurrence-distribution-and-sources-of-bisphenol-analogues-in-a-shallow-chinese-freshwater-lake-taihu-lake-implications-for-ecological-and-human-health-risk
#17
Yanhua Liu, Shenghu Zhang, Ninghui Song, Ruixin Guo, Meihong Chen, Dina Mai, Zhengyu Yan, Zhihua Han, Jianqiu Chen
Since the production and use of BPA were regulated in China around 2008, several bisphenol analogues were widely used to substitute BPA in the manufacture of polycarbonates, epoxy resins, and plastics. However, there is limited understanding of the spatial distribution, potential sources and risk assessment for those bisphenol analogues. In this study, seven bisphenol analogues were investigated in water and sediment samples from Taihu Lake, China. Compared to the same lake in 2013 (range: 5.4-87ng/L for waters and 0...
May 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28511040/removal-of-selected-ppcps-edcs-and-antibiotic-resistance-genes-in-landfill-leachate-by-a-full-scale-constructed-wetlands-system
#18
Xinzhu Yi, Ngoc Han Tran, Tingru Yin, Yiliang He, Karina Yew-Hoong Gin
Landfill leachate could be a significant source of emerging contaminants (ECs) and antibiotic resistance genes (ARGs) into the environment. This study provides the first information on the occurrence of selected ECs and ARGs in raw leachate from 16-year old closed landfill site in Singapore. Among the investigated ECs, acetaminophen (ACT), bisphenol A (BPA), clofibric acid (CA), caffeine (CF), crotamiton (CTMT), diclofenac (DCF), N,N-diethyl-m-toluamide (DEET), gemfibrozil (GFZ), lincomycin (LIN), salicylic acid (SA), and sulfamethazine (SMZ) were the most frequently detected compounds in raw landfill leachate...
May 8, 2017: Water Research
https://www.readbyqxmd.com/read/28505529/influence-of-bisphenol-a-on-the-transport-and-deposition-behaviors-of-bacteria-in-quartz-sand
#19
Dan Wu, Lei He, Ruonan Sun, Meiping Tong, Hyunjung Kim
The influence of Bisphenol A (BPA) on the transport and deposition behaviors of bacteria in quartz sand was examined in both NaCl (10 and 25 mM) and CaCl2 solutions (1.2 and 5 mM) by comparing the breakthrough curves and retained profiles of cell with BPA in suspensions versus those without BPA. Gram-negative Escherichia coli and Gram-positive Bacillus subtilis were employed as model cells in the present study. The extended Derjaguin-Landau-Verwey-Overbeek interaction energy calculation revealed that the presence of BPA in cell suspensions led to a lower repulsive interaction between the cells and the quartz sand...
May 7, 2017: Water Research
https://www.readbyqxmd.com/read/28505145/dna-methylation-targets-influenced-by-bisphenol-a-and-or-genistein-are-associated-with-survival-outcomes-in-breast-cancer-patients
#20
Rohit R Jadhav, Julia Santucci-Pereira, Yao V Wang, Joseph Liu, Theresa D Nguyen, Jun Wang, Sarah Jenkins, Jose Russo, Tim H-M Huang, Victor X Jin, Coral A Lamartiniere
Early postnatal exposures to Bisphenol A (BPA) and genistein (GEN) have been reported to predispose for and against mammary cancer, respectively, in adult rats. Since the changes in cancer susceptibility occurs in the absence of the original chemical exposure, we have investigated the potential of epigenetics to account for these changes. DNA methylation studies reveal that prepubertal BPA exposure alters signaling pathways that contribute to carcinogenesis. Prepubertal exposure to GEN and BPA + GEN revealed pathways involved in maintenance of cellular function, indicating that the presence of GEN either reduces or counters some of the alterations caused by the carcinogenic properties of BPA...
May 15, 2017: Genes
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