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https://www.readbyqxmd.com/read/26874516/identification-of-relationships-between-interleukin-15-mrna-and-brain-derived-neurotrophic-factor-ii-mrna-levels-with-formal-components-of-temperament-in-asthmatic-patients
#1
Michał Panek, Mateusz Jonakowski, Jan Zioło, Tadeusz Pietras, Łukasz Wieteska, Beata Małachowska, Łukasz Mokros, Janusz Szemraj, Piotr Kuna
Asthma is a chronic inflammatory and heterogeneous disease developing mostly through allergic inflammation, which modifies the expression of various cytokines and neurotrophins. Previous studies suggest the involvement of interleukin (IL)-15 in the regulation of immune response in asthma. Brain-derived neurotrophic factor (BDNF) II plays an important role as a regulator of development and survival of neurons as well as maintenance of their physiological activity. Chronic stress associated with asthma and elevated IL-15 mRNA and BDNFII mRNA levels may affect the mood and a subjective sensation of dyspnoea-inducing anxiety...
February 13, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/26556085/potential-therapeutic-effects-of-physical-exercise-for-bipolar-disorder
#2
REVIEW
Alberto Souza de Sá Filho, Antonio Marcos de Souza Moura, Murilo Khede Lamego, Nuno Barbosa Ferreira Rocha, Flávia Paes, Ana Cristina Oliveira, Eduardo Lattari, Ridson Rimes, João Manochio, Henning Budde, Mirko Wegner, Gioia Mura, Oscar Arias-Carrión, Elie Cheniaux, Ti-Fei Yuan, Antonio Egidio Nardi, Sergio Machado
Cognitive deficits are observed in a variety of domains in patients with bipolar disorder (BD). These deficits are attributed to neurobiological, functional and structural brain factors, particularly in prefrontal cortex. Furthermore, cortical alterations in each phase (mania/hypomania, euthymia and depression) are also present. A growing basis of evidence supports aerobic exercise as an alternative treatment method for BD symptoms. Its benefits for physical health in healthy subjects and some psychiatric disorders are fairly established; however evidence directly addressed to BD is scant...
2015: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/26556073/aerobic-exercise-does-not-predict-brain-derived-neurotrophic-factor-and-cortisol-alterations-in-depressed-patients
#3
REVIEW
Murilo Khede Lamego, Antonio Marcos de Souza Moura, Flávia Paes, Nuno Barbosa Ferreira Rocha, Alberto Souza de Sá Filho, Eduardo Lattari, Ridson Rimes, João Manochio, Henning Budde, Mirko Wegner, Gioia Mura, Oscar Arias-Carrión, Ti-Fei Yuan, Antonio Egidio Nardi, Sergio Machado
The pathophysiology of depression is related to neurobiological changes that occur in the monoamine system, hypothalamic-pituitary-adrenal axis, neurogenesis system and the neuroimmune system. In recent years, there has been a growing interest in the research of the effects of exercise on brain function, with a special focus on its effects on brain-derived neurotrophic factor (BDNF), cortisol and other biomarkers. Thus, the aim of this study is to present a review investigating the acute and chronic effects of aerobic exercise on BDNF and cortisol levels in individuals with depression...
2015: CNS & Neurological Disorders Drug Targets
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