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https://www.readbyqxmd.com/read/28817393/increased-expiratory-computed-tomography-density-reveals-possible-abnormalities-in-radiologically-preserved-lung-parenchyma-in-idiopathic-pulmonary-fibrosis
#1
Valentina Petroulia, Manuela Funke, Pascal Zumstein, Sabina Berezowska, Lukas Ebner, Thomas Geiser, Nenad Torbica, Johannes Heverhagen, Alexander Poellinger
OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive lethal chronic lung disease with unclear pathogenesis. Radiological hallmark is the pattern of usual interstitial pneumonia accentuated in peripheral and basal areas with otherwise preserved lung structure. One hypothesis is that alveolar collapse and consequent induration lead to fibrotic transformation of lung tissue. The aim of the study was to investigate normal-appearing tissue during expiration for signs of collapsibility and differences from other diseases or controls...
August 16, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28816974/efficacy-of-cortico-cancellous-composite-allograft-in-treatment-of-cervical-spondylosis
#2
Jung-Ho Park, Yoon-Kwang Bae, Seung-Woo Suh, Jae-Hyuk Yang, Jae-Young Hong
This was a prospective comparative study.The aim of this study was to compare the clinical and radiologic outcomes of patients treated with cortico/cancellous composite allograft or autoiliac bone graft in anterior cervical discectomy and fusion.Several methods have been developed to fuse the cervical spine for treatment of cervical spondylosis. Cortico/cancellous composite allograft might be another alternative.A total of 46 patients who underwent surgery for treatment of cervical spondylosis were evaluated between September 2010 and January 2015...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816960/successful-open-reduction-and-internal-fixation-for-displaced-femoral-fracture-in-a-patient-with-osteopetrosis-case-report-and-lessons-learned
#3
Jiangfa Huang, Jianke Pan, Mingtao Xu, Shuchai Xu
RATIONALE: Osteopetrosis is a rare disease that predominantly occurs in descendants of inbreeding families. In the case of fractures happen in patients with osteopetrosis, the choice between operative or conservative treatment is still controversial. Open reduction and internal fixation (ORIF) is a conventional treatment for fractures, and it possesses more applicability than conservative treatment. During this surgical treatment, ensure that bone union in the right way is pivotal to success and simultaneously prevents refracture and displacement after the operation...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816953/peritumoral-decreased-uptake-area-of-gadoxetic-acid-enhanced-magnetic-resonance-imaging-and-tumor-recurrence-after-surgical-resection-in-hepatocellular-carcinoma-a-strobe-compliant-article
#4
Seung Kak Shin, Yun Soo Kim, Young Sup Shim, Seung Joon Choi, So Hyun Park, Dong Hae Jung, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim
Recently, it has been suggested that peritumoral decreased uptake area (PDUA) in the hepatobiliary phase (HBP) of gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) was associated with vascular invasion in hepatocellular carcinoma (HCC). We aimed to investigate correlations between microvascular invasion and PDUA, and elucidate the predictability of PDUA for tumor recurrence after resection.We retrospectively analyzed clinicopathological and radiological data from 126 consecutive patients with single HCC ≤5 cm without macrovascular invasion who underwent preoperative Gd-EOB-DTPA-enhanced MRI and surgical resection...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816947/kinematic-analysis-of-the-relationship-between-modic-changes-and-sagittal-balance-parameters-in-the-cervical-spine
#5
Zikun Ma, Peng Liu, Jingpei Liu, Jianhui Mou, Zhaolin Wang, Dong Sun, Jie Cheng, Dengwei Zhang, Jianlin Xiao
The aim of this study is to investigate the relationship between the Modic changes (MCs) and sagittal parameters of the cervical spine.We conducted a retrospective review of 100 outpatients with magnetic resonance imaging (MRI) scans of the cervical spine (50 male and 50 female). MRI parameters were measured, including neck tilt, T1 slope (T1 ), thoracic inlet angle (TIA), and cervical lordosis (CL: Cobb C2-7). Patients were divided into 4 groups according to the presence or absence of MC and T1s, respectively: MC(+) and MC(-) groups, as well as H-T1s (T1s ≥25°) and L-T1s subgroups (T1s <25°)...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816932/postmenopausal-choriocarcinoma-a-rare-case-report-and-review-of-the-literature
#6
Na Guo, Rutie Yin, Qingli Li, Liang Song, Danqing Wang
OBJECTIVE: Choriocarcinoma is rare in postmenopausal women, and an early diagnosis contributes to a potential cure. METHODS: We report a rare case of a postmenopausal woman with choriocarcinoma. The 61-year-old patient presented with irregular vaginal bleeding, 11 years after menopause and 30 years after the birth of the last child. RESULTS: Radiological investigation found a 3-cm mass on the lower left part of the vaginal wall, and also bilateral lung nodules...
August 14, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28816821/adjacent-segment-disease-after-cervical-spine-fusion-evaluation-of-a-70-patient-long-term-follow-up
#7
Mohamed Alhashash, Mootaz Shousha, Heinrich Boehm
STUDY DESIGN: A retrospective study of 70 patients undergoing surgical treatment for adjacent segment disease (ASD) after anterior cervical decompression and fusion (ACDF). OBJECTIVES: To analyze the risk factors for the development of ASD in patients who underwent ACDF. SUMMARY OF BACKGROUND DATA: ACDF has provided a high rate of clinical success for the cervical degenerative disc disease; nevertheless, adjacent segment degeneration has been reported as a complication at the adjacent level secondary to the rigid fixation...
August 14, 2017: Spine
https://www.readbyqxmd.com/read/28816800/acute-sickle-cell-orbitopathy-masquerading-as-orbital-cellulitis
#8
Christopher M Stewart, Zuzana Sipkova, Goran D Hildebrand, Jonathan H Norris
Sickle cell orbitopathy is a rare manifestation of a sickle cell crisis and can closely mimic orbital cellulitis, both clinically and radiologically. We present a case where a child presented with what was thought to be orbital cellulitis and was treated accordingly. Subtle radiologic features of sickle cell orbitopathy were initially overlooked, resulting in an incorrect diagnosis and a treatment delay for the patient. Correctly treated most cases resolve with no adverse affects, highlighting how important it is to consider acute sickle cell orbitopathy in the differential diagnosis of acute periorbital swelling in children with sickle disease...
August 14, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28816756/characterizing-the-posttransfer-period-among-patients-with-pediatric-onset-ibd-the-impact-of-academic-versus-community-adult-care-on-emergent-health-resource-utilization
#9
Natasha Bollegala, Eric I Benchimol, Anne M Griffiths, Adrienne Kovacs, Allan H Steinhart, Xinbei Zhao, Geoffrey C Nguyen
BACKGROUND: Patients diagnosed with inflammatory bowel disease (IBD) during childhood require transfer to an adult gastroenterologist, in Ontario usually just before their 18th birthday. Pediatric onset IBD is a complex phenotype with demonstrated noncompliance risk that may require targeted measures to optimize health care outcomes in the adult care setting. PURPOSE: The purpose of this study was to determine the impact of posttransfer health care setting (academic versus community gastroenterologist) on emergent health resource utilization...
September 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28816746/characterizing-the-posttransfer-period-among-patients-with-pediatric-onset-ibd-the-impact-of-academic-versus-community-adult-care-on-emergent-health-resource-utilization
#10
Natasha Bollegala, Eric I Benchimol, Anne M Griffiths, Adrienne Kovacs, Allan H Steinhart, Xinbei Zhao, Geoffrey C Nguyen
BACKGROUND: Patients diagnosed with inflammatory bowel disease (IBD) during childhood require transfer to an adult gastroenterologist, in Ontario usually just before their 18th birthday. Pediatric onset IBD is a complex phenotype with demonstrated noncompliance risk that may require targeted measures to optimize health care outcomes in the adult care setting. PURPOSE: The purpose of this study was to determine the impact of posttransfer health care setting (academic versus community gastroenterologist) on emergent health resource utilization...
August 14, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28816695/audiological-and-radiological-characteristics-in-incomplete-partition-malformations
#11
Merve Özbal Batuk, Betül Çiçek Çınar, Burçe Özgen, Gonca Sennaroğlu, Levent Sennaroğlu
OBJECTIVE: To compare the audiological and radiological findings of patients with incomplete partition malformations (IPs) and analyze the relationship between the audiological and radiological findings. MATERIALS AND METHODS: The study included 84 patients (168 ears) with IPs as follows: 26 patients with Type I;IP-I (41 ears), 54 patients with Type II;IP-II (108 ears), and 4 patients with Type III;IP-III (8 ears). Remaining 11 ears were diagnosed with other inner ear malformations...
August 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28816643/pharmacometabolomics-informs-quantitative-radiomics-for-glioblastoma-diagnostic-innovation
#12
Theodora Katsila, Minos-Timotheos Matsoukas, George P Patrinos, Dimitrios Kardamakis
Applications of omics systems biology technologies have enormous promise for radiology and diagnostics in surgical fields. In this context, the emerging fields of radiomics (a systems scale approach to radiology using a host of technologies, including omics) and pharmacometabolomics (use of metabolomics for patient and disease stratification and guiding precision medicine) offer much synergy for diagnostic innovation in surgery, particularly in neurosurgery. This synthesis of omics fields and applications is timely because diagnostic accuracy in central nervous system tumors still challenges decision-making...
August 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28816234/novel-mutations-of-tcirg1-cause-a-malignant-and-mild-phenotype-of-autosomal-recessive-osteopetrosis-aro-in-four-chinese-families
#13
Xiao-Ya Zhang, Jin-Wei He, Wen-Zhen Fu, Chun Wang, Zhen-Lin Zhang
Human autosomal recessive osteopetrosis (ARO), also known as infantile malignant osteopetrosis, is a rare genetic bone disorder that often causes death. Mutations in T-cell immune regulator 1 (TCIRG1) are a frequent cause of human ARO. Six additional genes (TNFSF11, TNFRSF11A, CLCN7, OSTM1, SNX10, PLEKHM1) were also found to be associated with human ARO. In order to expand the mutation spectrum and clinical diversity for a better understanding of the ARO phenotype and to further investigate the clinical characteristics of benign subjects with ARO, we here report five individuals with ARO from four unrelated Chinese families...
August 17, 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/28816212/scrub-typhus-a-prospective-observational-study-during-an-outbreak-in-rajasthan-india
#14
Rajendra Prasad Takhar, Moti Lal Bunkar, Savita Arya, Nitin Mirdha, Arif Mohd
BACKGROUND: Scrub typhus, a potentially fatal rickettsial infection, is common in India. It usually presents with acute febrile illness along with multi-organ involvement caused by Orientia tsutsugamushi. As there was an outbreak of scrub typhus in the Hadoti region of Rajasthan and there is a paucity of data from this region, we studied this entity to describe the diverse epidemiological, clinico-radiological, laboratory parameters and outcome profile of patients with scrub typhus in a tertiary care hospital...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28816186/reliability-of-orthopantomography-and-cone-beam-computed-tomography-in-presurgical-implant-planning-a-clinical-study
#15
Jasjit Sahota, Aditya Bhatia, Megha Gupta, Vishal Singh, Juhi Soni, Richa Soni
BACKGROUND: Preoperative diagnosis and treatment planning are fundamental requirements to ensure success rate of implant. Cone-beam computed tomography (CBCT) provides all three dimensions and has been proved as a tool for radiology, especially in the success of implant. This study was conducted to evaluate the reliability of orthopantomography (OPG) and CBCT in presurgical implant planning. MATERIALS AND METHODS: The study was conducted on 110 partially or completely edentulous adult patients (male 50 and female 60)...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28816139/total-mesorectal-excision-versus-local-excision-after-favorable-response-to-preoperative-chemoradiotherapy-in-early-clinical-t3-rectal-cancer-a-propensity-score-analysis
#16
Young Seob Shin, Chang Sik Yu, Jin-Hong Park, Jin Cheon Kim, Seok-Byung Lim, In Ja Park, Tae Won Kim, Yong Sang Hong, Kyu-Pyo Kim, Sang Min Yoon, Ji Hyeon Joo, Jong Hoon Kim
PURPOSE: To compare oncological outcomes of total mesorectal excision (TME) and local excision (LE) in patients with "early" clinical T3 rectal cancer who received preoperative chemoradiotherapy (PCRT). METHODS AND MATERIALS: "Early" clinical T3 rectal cancer was radiologically defined as tumors with extramural extension of <5 mm without mesorectal fascia involvement and lateral lymph node metastasis. Patients with "early" clinical T3 rectal cancer who received PCRT followed by TME or LE between January 2007 and December 2013 were retrospectively analyzed...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28815556/trends-in-indications-complications-and-outcomes-for-venous-resection-during-pancreatoduodenectomy
#17
D Kleive, M A Sahakyan, A E Berstad, C S Verbeke, I P Gladhaug, B Edwin, B Fosby, P-D Line, K J Labori
BACKGROUND: Pancreatoduodenectomy with superior mesenteric-portal vein resection has become a common procedure in pancreatic surgery. The aim of this study was to compare standard pancreatoduodenectomy with pancreatoduodenectomy plus venous resection at a high-volume centre, and to examine trends in management and outcome over a decade for the latter procedure. METHODS: This retrospective observational study included all patients undergoing pancreatoduodenectomy with or without venous resection at Oslo University Hospital between January 2006 and December 2015...
August 17, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28815363/the-use-of-natural-language-processing-on-pediatric-diagnostic-radiology-reports-in-the-electronic-health-record-to-identify-deep-venous-thrombosis-in-children
#18
Jorge A Gálvez, Janine M Pappas, Luis Ahumada, John N Martin, Allan F Simpao, Mohamed A Rehman, Char Witmer
Venous thromboembolism (VTE) is a potentially life-threatening condition that includes both deep vein thrombosis (DVT) and pulmonary embolism. We sought to improve detection and reporting of children with a new diagnosis of VTE by applying natural language processing (NLP) tools to radiologists' reports. We validated an NLP tool, Reveal NLP (Health Fidelity Inc, San Mateo, CA) and inference rules engine's performance in identifying reports with deep venous thrombosis using a curated set of ultrasound reports...
August 16, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28815313/epidemiology-and-cerebrovascular-events-related-to-cervical-and-intracranial-arteries-dissection-the-experience-of-the-city-of-pisa
#19
N Giannini, L Ulivi, M Maccarrone, V Montano, G Orlandi, E Ferrari, C Cravcenco, U Bonuccelli, M Mancuso
Spontaneous dissection of cervical arteries (sCAD) is a major cause of ischemic stroke in young patients, with an incidence varying from 1.7 to 3/100,000/year for extracranial internal carotid artery (ICAD) and 1 to 1.9/100,000/year for extracranial vertebral artery (VAD). Reliable epidemiological data on stroke incidence related to sCAD are scarce in Italy. This study aims to evaluate the incidence, clinical features, and outcome of cerebrovascular events related to sCAD and spontaneous intracranial arteries dissections (sIAD) in the city of Pisa (Italy)...
August 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28815163/does-operative-or-nonoperative-treatment-achieve-better-results-in-a3-and-a4-spinal-fractures-without-neurological-deficit-systematic-literature-review-with-meta-analysis
#20
REVIEW
Elke Rometsch, Maarten Spruit, Roger Härtl, Robert Alton McGuire, Brigitte Sandra Gallo-Kopf, Vasiliki Kalampoki, Frank Kandziora
STUDY DESIGN: Systematic literature review with meta-analysis. OBJECTIVE: Thoracolumbar (TL) fractures can be treated conservatively or surgically. Especially, the treatment strategy for incomplete and complete TL burst fractures (A3 and A4, AOSpine classification) in neurologically intact patients remains controversial. The aim of this work was to collate the clinical evidence on the respective treatment modalities. METHODS: Searches were performed in PubMed and the Web of Science...
June 2017: Global Spine Journal
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