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Maxim Van den Bempt, Wouter Van Genechten, Toon Claes, Steven Claes
BACKGROUND: The aim of this study was to give an overview of the accuracy of coronal limb alignment correction after high tibial osteotomy (HTO) for the arthritic varus knee by performing a systematic review of the literature. METHODS: The databases PubMed, MEDLINE and Cochrane Library were screened for relevant articles. Only prospective clinical studies with the accuracy of alignment correction by performing HTO as primary or secondary objective were included...
October 21, 2016: Knee
Cynthia A Kahlenberg, Benedict U Nwachukwu, Kamran S Hamid, Michael E Steinhaus, Riley J Williams
PURPOSE: To evaluate reported medium- to long-term outcomes after high tibial osteotomy (HTO) with associated cartilage restoration procedures. METHODS: A review of the MEDLINE database was performed. The inclusion criteria were English language, clinical outcome study with HTO as the primary procedure, use of a form of cartilage repair included, and the mean follow-up period of at least 2 years. Each identified study was reviewed for study design, patient demographics, type of procedures performed, clinical outcomes, progression to total knee arthroplasty, and complications...
October 20, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Gerrit Bode, Ferdinand Kloos, Matthias J Feucht, Benjamin Fleischer, Norbert Südkamp, Philipp Niemeyer, Christoph Becher
PURPOSE: The unloading effect of an extra-articular absorber system on the knee joint medial compartment was compared with high tibial osteotomy (HTO) under physiological conditions in vitro. METHODS: Seven fresh-frozen cadaveric knees were used to test isokinetic flexion-extension motions under physiological loading using a biomechanical knee simulator. Tibiofemoral area contact and peak contact pressures were measured using pressure-sensitive film in the untreated medial compartment...
October 19, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Hendrik A Zuiderbaan, Jelle P van der List, Laura J Kleeblad, Pauline Appelboom, Nanne P Kort, Andrew D Pearle, Maarten V Rademakers
In this review, we evaluate the modern indications, subjective outcome scores, and survivorship results of unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) in the treatment of isolated medial compartment degeneration of the knee. In addition, in a thorough review of the literature, we evaluate global trends in the use of both methods. In our evaluation of articles, we note that inclusion criteria are relatively broader for UKA than for HTO, where age and body mass index should be considered before HTO surgery in order to optimize clinical outcome and survivorship results...
September 2016: American Journal of Orthopedics
Oui Sik Yoo, Yong Seuk Lee, Myung Chul Lee, Jae Hong Park, Jae Won Kim, Doo Hoon Sun
BACKGROUND: After open wedge high tibial osteotomy (OWHTO), the proximal fragment resembles the anatomy of the proximal tibia that is aligned in the anterior-posterior direction and the distal fragment resembles the anatomy of the mid shaft that is aligned in the proximal-distal direction. In addition, the medial portion of the proximal fragment becomes aligned medially and the medial portion of the distal fragment, laterally, depending on the magnitude of the posterior opening gap. Therefore, there would be a mismatch between the post-correction bony surface and the previous pre-contoured plate geometry...
October 10, 2016: BMC Musculoskeletal Disorders
Ayan Sarkar, Keshab Karmakar, Ashutosh K Singh, Kalyan Mandal, Gobinda Gopal Khan
This article demonstrates comprehensive studies on different visible-light driven photoelectrochemical and photocatalytic aspects of a hydrothermally synthesized n-type H2Ti3O7 (HTO) nanowire mesh and its carbon and nitrogen functionalized counterparts, namely C-HTO and N-HTO. It was found that the presence of various defect states within the band gap of HTO, C-HTO and N-HTO nanowires, make them photoactive under visible-light. The photo-conversion efficiencies of HTO, C-HTO, and N-HTO nanowire electrodes are about 0...
September 29, 2016: Physical Chemistry Chemical Physics: PCCP
Young Gon Na, Moon Jong Chang, Sang Hwa Eom, Seok Jin Kim, Seong Cheol Park, Tae Kyun Kim
BACKGROUND: We aimed to determine whether coronal alignment measured on the single-limb stance (SLS) radiographs differs from those on the double-limb stance (DLS) images. We also investigated whether the size of such differences was affected by the knee pathology, lower limb alignment, and geometry of the tibia or femur. METHODS: We measured coronal alignment with mechanical tibiofemoral angle (MTFA) on the DLS and SLS radiographs in patients with posterolateral rotatory instability (PLRI, 30 knees), osteoarthritis (OA) with varus deformity who were scheduled for high tibial osteotomy (HTO) (60 knees), and in normal control (60 knees)...
September 28, 2016: Knee
Jason Beng Teck Lim, Bryan Loh, Hwei Chi Chong, Andrew Hwee Chye Tan
BACKGROUND: Patients with a history of previous knee surgeries, such as anterior cruciate ligament reconstruction (ACLR) and high tibial osteotomy (HTO), often have a higher likelihood of requiring a subsequent total knee arthroplasty (TKA). However, there is relatively limited data, especially in the Asian population, on how previous knee surgery could affect the clinical outcomes of TKA. Therefore, this study aims to evaluate the impact of previous knee surgeries on the clinical outcomes of future TKA...
August 2016: Annals of Translational Medicine
James Yan, Volker Musahl, Jeffrey Kay, Moin Khan, Nicole Simunovic, Olufemi R Ayeni
PURPOSE: This systematic review evaluates radiographic and clinical outcome reporting following navigated high tibial osteotomy (HTO). Conventional HTO was used as a control to compare outcomes and furthermore investigate the quality of evidence in studies reporting outcomes for navigated HTO. It was hypothesized that navigated HTO will show superior clinical and radiographic outcomes compared to conventional HTO. METHODS: Two independent reviewers searched PubMed, Ovid (MEDLINE), EMBASE, and Cochrane databases for studies reporting outcomes following navigated HTO...
September 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Magali Cucchiarini, Laura de Girolamo, Giuseppe Filardo, J Miguel Oliveira, Patrick Orth, Dietrich Pape, Pascal Reboul
Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large population worldwide and for which there is no definitive cure. This review provides critical insights into the basic knowledge on OA that may lead to innovative end efficient new therapeutic regimens. While degradation of the articular cartilage is the hallmark of OA, with altered interactions between chondrocytes and compounds of the extracellular matrix, the subchondral bone has been also described as a key component of the disease, involving specific pathomechanisms controlling its initiation and progression...
December 2016: Journal of Experimental Orthopaedics
D Saragaglia, B Chedal-Bornu, R C Rouchy, B Rubens-Duval, R Mader, R Pailhé
PURPOSE: The goal of this article is to present our experience on navigation for osteotomies around the knee and especially osteotomies for coronal deformities. The first computer-assisted osteotomy was performed in March 2001 and since that time more than 1000 osteotomies have been performed in our department. METHODS: All the osteotomies were performed with the Orthopilot(®) device (B-Braun-Aesculap, Tuttlingen, Germany). The main indication was for genu varum deformities but several cases were operated for genu valgum...
September 1, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Seong-Il Bin, Hyun-Jung Kim, Hyeong-Sik Ahn, Daniel Sungku Rim, Dae-Hee Lee
PURPOSE: To test that patellar height decreases (patellar baja) after opening wedge high tibial osteotomy (HTO) and increases (patellar alta) after closing wedge HTO. In addition, this meta-analysis evaluated whether the method of measuring patellar height affected the change in patellar height after opening and closing HTO. METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, all studies comparing pre- and postoperative patellar height using various indices, including the Insall-Salvati index (ISI), Blackburne-Peel index, and Caton Deschamps index, in patients who underwent opening or closing wedge HTO were included...
August 25, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Omer Slevin, Olufemi R Ayeni, Stefan Hinterwimmer, Thomas Tischer, Matthias J Feucht, Michael T Hirschmann
PURPOSE: A variety of bone void filling materials and methods are available in opening medial wedge HTO (OWHTO). The pertinent question revolves around if and when bone void fillers are needed. The primary purpose of this study was to systematically review outcomes and complications after OWHTO with and without the use of bone void fillers. METHODS: The EMBASE, PubMed\MEDLINE, Cochrane Library and Google Scholar databases were searched to identify articles that reported OWHTO results using different bone void fillers until March 2016...
August 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Lorna J Dallas, Tim P Bean, Andrew Turner, Brett P Lyons, Awadhesh N Jha
Temperature is an abiotic factor of particular concern for assessing the potential impacts of radionuclides on marine species. This is particularly true for tritium, which is discharged as tritiated water (HTO) in the process of cooling nuclear institutions. Additionally, with sea surface temperatures forecast to rise 0.5-3.5 °C in the next 30-100 years, determining the interaction of elevated temperature with radiological exposure has never been more relevant. We assessed the tissue-specific accumulation, transcriptional expression of key genes, and genotoxicity of tritiated water to marine mussels at either 15 or 25 °C, over a 7 day time course with sampling after 1 h, 12 h, 3 d and 7d...
November 2016: Journal of Environmental Radioactivity
Dahee Jung, Dami Kim, Joonhee Park, Joo Young Lee
BACKGROUND: Insensible body mass loss (IBL) from the human body continuously occurs, which is an important component in body heat exchange. The purpose of this study was to examine the relevance of IBL to anthropometric characteristics and self-identified thermal tolerance. METHODS: A total of 289 healthy young Korean males were chosen and sorted into the following three groups: heat tolerable only (HTO, N = 79), cold tolerable only (CTO, N = 104), neither heat nor cold tolerable (NHC, N = 106)...
2016: Journal of Physiological Anthropology
J Thulasi Brindha, K R Sreedevi, C Manonmani, T Jesan, S Rajaram, P M Ravi, R M Tripathi
The field measurements of (3)H in the form of HTO present in air moisture carried out around Madras Atomic Power Station were compared with predicted values using atmospheric dispersion modeling. Air (3)H samples were collected from different sectors at the site boundary of the operating reactors for the period of 2 y and compared with Gaussian Plume model. The predictions were comparable with the measured value. The slight variation observed between the two methods is attributed to the uncertainty involved in the measurement of air (3)H concentration and in the measurement of site-specific meteorological parameters...
August 19, 2016: Radiation Protection Dosimetry
Joon Ho Wang, Jung Min Shin, Hyun Ho Kim, Seung-Hoon Kang, Byung Hoon Lee
PURPOSE: To evaluate the differences in the amount of varus malalignment and valgus (over) correction in relation to three different weight bearing conditions from whole leg AP radiographs (single-limb (SL) stance, double-limb (DL) stance, supine position (S)) before and after high tibial osteotomy (HTO), and to evaluate which alignment parameters affect the changes for patients in three different weight bearing conditions. METHODS: A total of 40 consecutive patients (43 knees) with varus osteoarthritis underwent navigation assisted open wedge HTO...
August 18, 2016: International Orthopaedics
Joong Il Kim, Bo Hyun Kim, Ki Woung Lee, Osung Lee, Hyuk Soo Han, Sahnghoon Lee, Myung Chul Lee
BACKGROUND: High tibial osteotomy (HTO) produces valgus limb alignment, and this change can affect lower limb length. PURPOSE: To compare the change in lower limb length and the discrepancy compared with the contralateral limb after unilateral lateral closing wedge HTO (CWHTO) and medial opening wedge HTO (OWHTO). STUDY DESIGN: Randomized controlled trial; Level of evidence, 1. METHODS: In this study, 30 knees undergoing unilateral CWHTO and 30 knees undergoing unilateral OWHTO for medial compartmental osteoarthritis were analyzed with 1-year follow-up...
August 8, 2016: American Journal of Sports Medicine
Anil S Ranawat, Benedict U Nwachukwu, Andrew D Pearle, Hendrik A Zuiderbaan, Kenneth D Weeks, Saker Khamaisy
BACKGROUND: Lateral closing-wedge (LCW) and medial opening-wedge (MOW) high tibial osteotomies (HTOs) correct varus knee alignment and stabilize the anterior cruciate ligament (ACL)-deficient knee. Tibiofemoral and patellofemoral alignment and kinematics after HTO are not well quantified. PURPOSE: To compare the effect of LCW and MOW HTO on tibiofemoral and patellofemoral alignment in the ACL-deficient knee. STUDY DESIGN: Controlled laboratory study...
August 5, 2016: American Journal of Sports Medicine
Sam Hopwood, Wasim Khan, Sanjeev Agarwal
BACKGROUND: High tibial osteotomy (HTO) is a treatment option for relatively young patients with isolated medial compartment arthritis of the knee. Medial open wedge osteotomies allow easier control of correction, but can lead to patella infera as a result of distalization of the tibial tubercle. This retrospective study reports results of a biplanar tibial tubercle preserving HTO, designed to preserve patellar height. METHODS: The study is a retrospective analysis of 12 consecutive patients (11 men, 1 woman) average age 39...
July 30, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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