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https://www.readbyqxmd.com/read/29334198/enzyme-based-glucose-sensor-from-invasive-to-wearable-device
#1
REVIEW
Hyunjae Lee, Yongseok Joseph Hong, Seungmin Baik, Taeghwan Hyeon, Dae-Hyeong Kim
Blood glucose concentration is a key indicator of patients' health, particularly for symptoms associated with diabetes mellitus. Because of the large number of diabetic patients, many approaches for glucose measurement have been studied to enable continuous and accurate glucose level monitoring. Among them, electrochemical analysis is prominent because it is simple and quantitative. This technology has been incorporated into commercialized and research-level devices from simple test strips to wearable devices and implantable systems...
January 15, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29333853/a-highly-sensitive-and-very-stretchable-strain-sensor-based-on-a-rubbery-semiconductor
#2
Hae-Jin Kim, Anish Thukral, Cunjiang Yu
There is a growing interest in developing stretchable strain sensors to quantify the large mechanical deformation and strain associated with the activities for a wide range of species, such as humans, machines, and robots. Here, we report a novel stretchable strain sensor entirely in a rubber format by using a solution processed rubbery semiconductor as the sensing material to achieve high sensitivity, large mechanical strain tolerance, hysteresis-less and highly linear responses. Specifically, the rubbery semiconductor exploits π-π stacked poly(3-hexylthiophene-2,5-diyl) nanofibrils (P3HT-NFs) percolated in silicone elastomer of polydimethylsiloxane (PDMS) to yield semiconducting nanocomposite with a large mechanical stretchability, although P3HT is a well-known nonstretchable semiconductor...
January 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29332423/first-experiences-with-a-wearable-multisensor-in-an-outpatient-glucose-monitoring-study-part-i-the-users-view
#3
Andreas Caduff, Mattia Zanon, Pavel Zakharov, Martin Mueller, Mark Talary, Achim Krebs, Werner A Stahel, Marc Donath
BACKGROUND: Extensive past work showed that noninvasive continuous glucose monitoring with a wearable Multisensor device worn on the upper arm provides useful information about glucose trends to improve diabetes therapy in controlled and semicontrolled conditions. METHODS: To test previous findings also in uncontrolled in-clinic and outpatient conditions, a long-term study has been conducted to collect Multisensor and reference glucose data in a population of 20 type 1 diabetes subjects...
January 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29331656/effect-of-a-wearable-patient-sensor-on-care-delivery-for-preventing-pressure-injuries-in-acutely-ill-adults-a-pragmatic-randomized-clinical-trial-ls-hapi-study
#4
David Pickham, Nic Berte, Mike Pihulic, Andre Valdez, Barbara Mayer, Manisha Desai
IMPORTANCE: Though theoretically sound, studies have failed to demonstrate the benefit of routine repositioning of at-risk patients for the prevention of hospital acquired pressure injuries. OBJECTIVE: To assess the clinical effectiveness of a wearable patient sensor to improve care delivery and patient outcomes by increasing the total time with turning compliance and preventing pressure injuries in acutely ill patients. DESIGN: Pragmatic, investigator initiated, open label, single site, randomized clinical trial...
December 30, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29330962/skin-conformal-polymer-electrodes-for-clinical-ecg-and-eeg-recordings
#5
Flurin Stauffer, Moritz Thielen, Christina Sauter, Séverine Chardonnens, Simon Bachmann, Klas Tybrandt, Christian Peters, Christofer Hierold, Janos Vörös
Preparation-free and skin compliant biopotential electrodes with high recording quality enable wearables for future healthcare and the Internet of Humans. Here, super-soft and self-adhesive electrodes are presented for use on dry and hairy skin without skin preparation or attachment pressure. The electrodes show a skin-contact impedance of 50 kΩ cm2 at 10 Hz that is comparable to clinical standard gel electrodes and lower than existing dry electrodes. Microstructured electrodes inspired by grasshopper feet adhere repeatedly to the skin with a force of up to 0...
January 13, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29330762/how-honest-are-the-signals-a-protocol-for-validating-wearable-sensors
#6
Varol Onur Kayhan, Zheng Chris Chen, Kimberly A French, Tammy D Allen, Kristen Salomon, Alison Watkins
There is growing interest among organizational researchers in tapping into alternative sources of data beyond self-reports to provide a new avenue for measuring behavioral constructs. Use of alternative data sources such as wearable sensors is necessary for developing theory and enhancing organizational practice. Although wearable sensors are now commercially available, the veracity of the data they capture is largely unknown and mostly based on manufacturers' claims. The goal of this research is to test the validity and reliability of data captured by one such wearable badge (by Humanyze) in the context of structured meetings where all individuals wear a badge for the duration of the encounter...
January 12, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29330476/high-performance-flexible-supercapacitors-based-on-electrochemically-tailored-three-dimensional-reduced-graphene-oxide-networks
#7
Taniya Purkait, Guneet Singh, Dinesh Kumar, Mandeep Singh, Ramendra Sundar Dey
A simple approach for growing porous electrochemically reduced graphene oxide (pErGO) networks on copper wire, modified with galvanostatically deposited copper foam is demonstrated. The as-prepared pErGO networks on the copper wire are directly used to fabricate solid-state supercapacitor. The pErGO-based supercapacitor can deliver a specific capacitance (Csp) as high as 81±3 F g-1 at 0.5 A g-1 with polyvinyl alcohol/H3PO4 gel electrolyte. The Csp per unit length and area are calculated as 40.5 mF cm-1 and 283...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330154/novel-wearable-seismocardiography-and-machine-learning-algorithms-can-assess-clinical-status-of-heart-failure-patients
#8
Omer T Inan, Maziyar Baran Pouyan, Abdul Q Javaid, Sean Dowling, Mozziyar Etemadi, Alexis Dorier, J Alex Heller, A Ozan Bicen, Shuvo Roy, Teresa De Marco, Liviu Klein
BACKGROUND: Remote monitoring of patients with heart failure (HF) using wearable devices can allow patient-specific adjustments to treatments and thereby potentially reduce hospitalizations. We aimed to assess HF state using wearable measurements of electrical and mechanical aspects of cardiac function in the context of exercise. METHODS AND RESULTS: Patients with compensated (outpatient) and decompensated (hospitalized) HF were fitted with a wearable ECG and seismocardiogram sensing patch...
January 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29328106/polymer-thermal-optical-switch-for-a-flexible-photonic-circuit
#9
Yue Sun, Yue Cao, Qi Wang, Yunji Yi, Xiaoqiang Sun, Yuanda Wu, Fei Wang, Daming Zhang
Flexible and wearable optoelectronic devices are the new trend for an active lifestyle. These devices are polymer-based for flexibility. We demonstrated flexible polymer waveguide optical switches for a flexible photonic integrated circuit. The optical switches are composed of a single-mode inverted waveguide with dimensions of 5 μm waveguide width, 3 μm ridge height, and 3 μm slab height. A Mach-Zehnder structure was used in the device, with the Y-branch horizontal length of 0.1 cm, the distance between two heating branches of 30 μm, and the heating branch length of 1 cm...
January 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29327335/classification-and-characterization-of-postural-transitions-using-instrumented-shoes
#10
Christopher Moufawad El Achkar, Constanze Lenbole-Hoskovec, Anisoara Paraschiv-Ionescu, Kristof Major, Kamiar Aminian, Christophe Büla
The frequency and quality of sit-to-stand and stand-to-sit postural transitions decrease with age and are highly relevant for fall risk assessment. Accurate classification and characterization of these transitions in daily life of older adults are therefore needed. In this study, we propose to use instrumented shoes for postural transition classification as well as transition duration estimation from insole force signals. In the first part, data were collected with 10 older adults and 10 young participants performing transitions in the laboratory while wearing the instrumented shoes, without arm assistance...
January 12, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29327220/patient-perceptions-and-preferences-for-a-mealtime-insulin-delivery-patch
#11
Mark Peyrot, Darlene Dreon, Vivien Zraick, Brett Cross, Meng H Tan
INTRODUCTION: A basal-bolus insulin regimen is needed to achieve glycated hemoglobin A1c (HbA1c) below 7.0% in people with type 1 (T1D) or type 2 (T2D) diabetes who have significant loss of beta-cell function. Nonadherence to therapy is common and negatively affects the ability to reach treatment goals. We examined patient assessment of a new, wearable mealtime insulin-delivery system (patch) relative to their current mealtime insulin-delivery system (syringe, pen, or pump). The patch is designed to deliver only boluses of fast-acting insulin (no basal insulin), mechanically controlled by the patient...
January 11, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29325208/bioinspired-universal-flexible-elastomer-based-microchannels
#12
Feng Wu, Songyue Chen, Baiyi Chen, Miao Wang, Lingli Min, Jack Alvarenga, Jie Ju, Ali Khademhosseini, Yuxing Yao, Yu Shrike Zhang, Joanna Aizenberg, Xu Hou
Flexible and stretchable microscale fluidic devices have a broad range of potential applications, ranging from electronic wearable devices for convenient digital lifestyle to biomedical devices. However, simple ways to achieve stable flexible and stretchable fluidic microchannels with dynamic liquid transport have been challenging because every application for elastomeric microchannels is restricted by their complex fabrication process and limited material selection. Here, a universal strategy for building microfluidic devices that possess exceptionally stable and stretching properties is shown...
January 11, 2018: Small
https://www.readbyqxmd.com/read/29324641/genetic-algorithm-based-motion-estimation-method-using-orientations-and-emgs-for-robot-controls
#13
Jeongsook Chae, Yong Jin, Yunsick Sung, Kyungeun Cho
Demand for interactive wearable devices is rapidly increasing with the development of smart devices. To accurately utilize wearable devices for remote robot controls, limited data should be analyzed and utilized efficiently. For example, the motions by a wearable device, called Myo device, can be estimated by measuring its orientation, and calculating a Bayesian probability based on these orientation data. Given that Myo device can measure various types of data, the accuracy of its motion estimation can be increased by utilizing these additional types of data...
January 11, 2018: Sensors
https://www.readbyqxmd.com/read/29324440/micro-patterned-graphene-based-sensing-skins-for-human-physiological-monitoring
#14
Long Wang, Kenneth J Loh, Wei-Hung Chiang, Kausik Manna
Ultrathin, flexible, conformal, and skin-like electronic transducers are emerging as promising candidates for noninvasive and nonintrusive human health monitoring. In this work, a wearable sensing membrane is developed by patterning a graphene-based solution onto ultrathin medical tapes, which can then be attached to the skin for monitoring human physiological parameters and physical activity. Here, the sensor is validated for monitoring finger bending/movements and for recognizing hand motion patterns, thereby demonstrating its future potential for evaluating athletic performance, physical therapy, and designing next-generation human-machine interfaces...
January 11, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29324240/cognitive-science-in-the-era-of-artificial-intelligence-a-roadmap-for-reverse-engineering-the-infant-language-learner
#15
Emmanuel Dupoux
Spectacular progress in the information processing sciences (machine learning, wearable sensors) promises to revolutionize the study of cognitive development. Here, we analyse the conditions under which 'reverse engineering' language development, i.e., building an effective system that mimics infant's achievements, can contribute to our scientific understanding of early language development. We argue that, on the computational side, it is important to move from toy problems to the full complexity of the learning situation, and take as input as faithful reconstructions of the sensory signals available to infants as possible...
January 8, 2018: Cognition
https://www.readbyqxmd.com/read/29323395/self-powered-implantable-electronic-skin-for-in-situ-analysis-of-urea-uric-acid-in-body-fluids-and-the-potential-applications-in-real-time-kidney-disease-diagnosis
#16
Wenyan Yang, Wuxiao Han, Huiling Gao, Linlin Zhang, Shuai Wang, Lili Xing, Yan Zhang, Xinyu Xue
As the concentration of different biomarkers in human body fluids are an important parameter of chronic disease, wearable biosensors for in situ analysis of body fluids with high sensitivity, real-time detection, flexibility and biocompatibility have significant potential therapeutic applications. In this paper, a flexible self-powered implantable electronic-skin (e-skin) for in situ body fluids analysis (urea/uric-acid) as a real-time kidney-disease diagnoser has been proposed based on the piezo-enzymatic-reaction coupling process of ZnO nanowire arrays...
January 11, 2018: Nanoscale
https://www.readbyqxmd.com/read/29323385/2d-end-to-end-carbon-nanotube-conductive-networks-in-polymer-nanocomposites-a-conceptual-design-to-dramatically-enhance-the-sensitivities-of-strain-sensors
#17
Jun-Hong Pu, Xiang-Jun Zha, Min Zhao, Shengyao Li, Rui-Ying Bao, Zheng-Ying Liu, Bang-Hu Xie, Ming-Bo Yang, Zhanhu Guo, Wei Yang
New generation wearable devices require mechanically compliant strain sensors with a high sensitivity in a full detecting range. Herein, novel 2D end-to-end contact conductive networks of multi-walled carbon nanotubes (MWCNTs) were designed and realized in an ethylene-α-octene block copolymer (OBC) matrix. The prepared strain sensor showed a high gauge factor (GF) of 248 even at a small strain (5%) and a linear resistance response throughout the whole strain range. The sensors also exhibited very good stretchability up to 300% and high cycling durability...
January 11, 2018: Nanoscale
https://www.readbyqxmd.com/read/29323376/a-multifunctional-wearable-sensor-based-on-a-graphene-inverse-opal-cellulose-film-for-simultaneous-in-situ-monitoring-of-human-motion-and-sweat
#18
Hua Xu, Yi Fei Lu, Jian Xin Xiang, Ming Kun Zhang, Yuan Jin Zhao, Zhuo Ying Xie, Zhong Ze Gu
A multifunctional, wearable sensor based on a reduced oxide graphene (rGO) film onto a porous inverse opal acetylcellulose (IOAC) film has been developed and can perform simultaneous, in situ monitoring of various human motions and ion concentrations in sweat. The rGO film is used as a strain-sensing layer for monitoring human motion via its resistance change, whereas the porous IOAC film is used as a flexible microstructured substrate not only for high sensitive motion sensing, but also for collection and analysis of ion concentrations in sweat by its simple colorimetric changes or reflection-peak shifts...
January 11, 2018: Nanoscale
https://www.readbyqxmd.com/read/29322351/from-pacemaker-to-wearable-techniques-for-ecg-detection-systems
#19
REVIEW
Ashish Kumar, Rama Komaragiri, Manjeet Kumar
With the alarming rise in the deaths due to cardiovascular diseases (CVD), present medical research scenario places notable importance on techniques and methods to detect CVDs. As adduced by world health organization, technological proceeds in the field of cardiac function assessment have become the nucleus and heart of all leading research studies in CVDs in which electrocardiogram (ECG) analysis is the most functional and convenient tool used to test the range of heart-related irregularities. Most of the approaches present in the literature of ECG signal analysis consider noise removal, rhythm-based analysis, and heartbeat detection to improve the performance of a cardiac pacemaker...
January 11, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29321637/detection-of-american-football-head-impacts-using-biomechanical-features-and-support-vector-machine-classification
#20
Lyndia C Wu, Calvin Kuo, Jesus Loza, Mehmet Kurt, Kaveh Laksari, Livia Z Yanez, Daniel Senif, Scott C Anderson, Logan E Miller, Jillian E Urban, Joel D Stitzel, David B Camarillo
Accumulation of head impacts may contribute to acute and long-term brain trauma. Wearable sensors can measure impact exposure, yet current sensors do not have validated impact detection methods for accurate exposure monitoring. Here we demonstrate a head impact detection method that can be implemented on a wearable sensor for detecting field football head impacts. Our method incorporates a support vector machine classifier that uses biomechanical features from the time domain and frequency domain, as well as model predictions of head-neck motions...
December 21, 2017: Scientific Reports
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