keyword
MENU ▼
Read by QxMD icon Read
search

Appropriateness

keyword
https://www.readbyqxmd.com/read/28212541/analysis-of-variability-in-high-throughput-screening-data-applications-to-melanoma-cell-lines-and-drug-responses
#1
Kuan-Fu Ding, Darren Finlay, Hongwei Yin, William P D Hendricks, Chris Sereduk, Jeffrey Kiefer, Aleksandar Sekulic, Patricia M LoRusso, Kristiina Vuori, Jeffrey M Trent, Nicholas J Schork
High-throughput screening (HTS) strategies and protocols have undergone significant development in the last decade. It is now possible to screen hundreds of thousands of compounds, each exploring multiple biological phenotypes and parameters, against various cell lines or model systems in a single setting. However, given the vast amount of data such studies generate, the fact that they use multiple reagents, and are often technician-intensive, questions have been raised about the variability, reliability and reproducibility of HTS results...
February 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212516/sex-disparities-in-substance-abuse-research-evaluating-23-years-of-structural-neuroimaging-studies
#2
Kimberly E Lind, Eric J Gutierrez, Dorothy J Yamamoto, Michael F Regner, Sherry A McKee, Jody Tanabe
BACKGROUND: Sex differences in brain structure and clinical course of substance use disorders underscores the need to include women in structural brain imaging studies. The NIH has supported the need for research to address sex differences. We evaluated female enrollment in substance abuse structural brain imaging research and the methods used to study sex differences in substance effects. METHODS: Structural brain imaging studies published through 2016 (n=230) were evaluated for number of participants by sex and substance use status and methods used to evaluate sex differences...
January 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28212496/antipsychotic-use-in-dementia
#3
Julia Kirkham, Chelsea Sherman, Clive Velkers, Colleen Maxwell, Sudeep Gill, Paula Rochon, Dallas Seitz
Antipsychotics are necessary for many older adults to treat major mental illnesses or reduce distressing psychiatric symptoms. Current controversy exists over the role of antipsychotics in the management of neuropsychiatric symptoms (NPS) in persons with dementia. Although some NPS may be appropriately and safely treated with antipsychotics, a fine balance must be achieved between the benefits of these medications, which are often modest, and adverse events, which may have significant consequences. Approximately one-third of all persons with dementia are currently prescribed antipsychotic medications, and there is significant variation in the use of antipsychotics across care settings and providers...
March 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28212482/-using-polypropylene-mesh-in-surgery-for-stress-urinary-incontinence
#4
Erick Arturo Murguía-Flores, Fernando Quintero-Granados, Luis Guillermo Torres-Gómez, Mariela Mariela Chávez-Navarro, Martha Berenice Vázquez-Gómez, Elizabeth Rodríguez-Rodríguez
BACKGROUND: Stress urinary incontinence (SUI) is defined as the involuntary leakage of urine while making an effort, such as coughing, sneezing or during activity. Since SUI generates high costs and affects the quality of life, it is important to make a proper diagnosis and, consequently, manage SUI efficiently. The objective was to know whether it is appropriate to use polypropylene mesh for SUI. METHODS: A historical cohort was conducted by reviewing records of patients with SUI treated with polypropylene mesh during 2013 with a follow-up of 12 months...
2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28212449/energy-intake-and-energy-expenditure-of-pre-professional-female-contemporary-dancers
#5
Meghan A Brown, Glyn Howatson, Edel Quin, Emma Redding, Emma J Stevenson
Many athletes in aesthetic and weight dependent sports are at risk of energy imbalance. However little is known about the exercise and eating behaviours of highly trained dance populations. This investigation sought to determine the energy intake and energy expenditure of pre-professional female contemporary dancers. Twenty-five female contemporary dance students completed the study. Over a 7-day period, including five week days (with scheduled dance training at a conservatoire) and two weekend days (with no scheduled dance training at the conservatoire), energy intake (self-reported weighed food diary and 24 h dietary recall) and expenditure (tri-axial accelerometry) were recorded...
2017: PloS One
https://www.readbyqxmd.com/read/28212400/surveys-of-public-knowledge-and-attitudes-with-regard-to-antibiotics-in-poland-did-the-european-antibiotic-awareness-day-campaigns-change-attitudes
#6
Beata Mazińska, Izabela Strużycka, Waleria Hryniewicz
BACKGROUND: Antimicrobial resistance is a global public health problem. Monitoring the level of knowledge regarding antibiotics is a part of the European Union Community strategy against antimicrobial resistance. OBJECTIVE: To assess knowledge by the general public in Poland regarding antibiotics, AMR, and the impact of the European Antibiotic Awareness Day campaigns. METHODS: The repeated cross-sectional study was developed and carried out among the general public in Poland (in 5 waves between 2009 and 2011, embracing a total of 5004 respondents)...
2017: PloS One
https://www.readbyqxmd.com/read/28212392/what-s-in-a-game-a-systems-approach-to-enhancing-performance-analysis-in-football
#7
Scott McLean, Paul M Salmon, Adam D Gorman, Gemma J M Read, Colin Solomon
PURPOSE: Performance analysis (PA) in football is considered to be an integral component of understanding the requirements for optimal performance. Despite vast amounts of research in this area key gaps remain, including what comprises PA in football, and methods to minimise research-practitioner gaps. The aim of this study was to develop a model of the football match system in order to better describe and understand the components of football performance. Such a model could inform the design of new PA methods...
2017: PloS One
https://www.readbyqxmd.com/read/28212351/black-box%C3%A2-gastrointestinal%C3%A2-tract-needs%C3%A2-and%C3%A2-prospects%C3%A2-of%C3%A2-gaining%C3%A2-insights%C3%A2-of%C3%A2-fate%C3%A2-of%C3%A2-fat-%C3%A2-protein-%C3%A2-and%C3%A2-starch%C3%A2-in%C3%A2-case%C3%A2-of%C3%A2-exocrine%C3%A2-pancreatic%C3%A2-insufficiency%C3%A2-by%C3%A2-using%C3%A2-fistulated%C3%A2-pigs
#8
REVIEW
Anne Mößeler, Josef Kamphues
Exocrine pancreatic insufficiency (EPI) results in the maldigestion and malabsorption of nutrients. The digestive processes in humans and other monogastric species like rat and pig are characterized by a predominantly enzymatic digestion within the small intestine and microbial fermentation located in the hindgut. For protein, it is doctrine that only prececally absorbed amino acids can be transferred to the amino acid pool of the host, while postileal absorption of nitrogen-containing compounds occurs mainly in the form of ammonia, being a burden rather than a benefit for the organism...
February 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28212290/defining-clinical-response-criteria-and-early-response-criteria-for-precision-oncology-current-state-of-the-art-and-future-perspectives
#9
Vivek Subbiah, Hubert H Chuang, Dhiraj Gambhire, Kalevi Kairemo
In this era of precision oncology, there has been an exponential growth in the armamentarium of genomically targeted therapies and immunotherapies. Evaluating early responses to precision therapy is essential for "go" versus "no go" decisions for these molecularly targeted drugs and agents that arm the immune system. Many different response assessment criteria exist for use in solid tumors and lymphomas. We reviewed the literature using the Medline/PubMed database for keywords "response assessment" and various known response assessment criteria published up to 2016...
February 15, 2017: Diagnostics
https://www.readbyqxmd.com/read/28212285/transcriptomic-analysis-reveals-selective-metabolic-adaptation-of-streptococcus-suis-to-porcine-blood-and-cerebrospinal-fluid
#10
Anna Koczula, Michael Jarek, Christian Visscher, Peter Valentin-Weigand, Ralph Goethe, Jörg Willenborg
Streptococcus suis is a zoonotic pathogen that can cause severe pathologies such as septicemia and meningitis in its natural porcine host as well as in humans. Establishment of disease requires not only virulence of the infecting strain but also an appropriate metabolic activity of the pathogen in its host environment. However, it is yet largely unknown how the streptococcal metabolism adapts to the different host niches encountered during infection. Our previous isotopologue profiling studies on S. suis grown in porcine blood and cerebrospinal fluid (CSF) revealed conserved activities of central carbon metabolism in both body fluids...
February 15, 2017: Pathogens
https://www.readbyqxmd.com/read/28212212/neuromuscular-blocking-agents-during-electroconvulsive-therapy-was-the-crossover-design-appropriate-and-valid
#11
Mahmoud Daoud
No abstract text is available yet for this article.
February 16, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28212203/adding-examples-to-the-asa-physical-status-classification-improves-correct-assignment-to-patients
#12
Erin E Hurwitz, Michelle Simon, Sandhya R Vinta, Charles F Zehm, Sarah M Shabot, Abu Minhajuddin, Amr E Abouleish
BACKGROUND: Despite its widespread use, the American Society of Anesthesiologists (ASA)-Physical Status Classification System has been shown to result in inconsistent assignments among anesthesiologists. The ASA-Physical Status Classification System is also used by nonanesthesia-trained clinicians and others. In 2014, the ASA developed and approved examples to assist clinicians in determining the correct ASA-Physical Status Classification System assignment. The effect of these examples by anesthesia-trained and nonanesthesia-trained clinicians on appropriate ASA-Physical Status Classification System assignment in hypothetical cases was examined...
February 17, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28212202/psychometric-evaluation-of-the-adolescent-health-promotion-scale-in-chile-differences-by-socioeconomic-status-and-gender
#13
Cristian A Rojas-Barahona, Jorge Gaete, Esterbina Olivares, Carla E Förster, Eugenio Chandia, Mei-Yen Chen
BACKGROUND: The promotion of healthy behaviors is a relevant issue worldwide, especially among adolescent populations, as this is the developmental stage where most unhealthy behaviors become ingrained. PURPOSE: The aim of this study was to analyze the psychometric properties of the Spanish version of the Adolescent Health Promotion Scale (AHPS) in a Chilean sample of early adolescents. METHODS: The sample was composed of 1,156 adolescents aged 10-14 years from schools in San Felipe, Chile...
February 16, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28212196/prison-nursing-formation-of-a-stable-professional-identity
#14
Khurshid Choudhry, David Armstrong, Alexandru Dregan
AIM: The aim of this study was to analyze how working within prison environments can influence the self-identity and professional identity of nurses. BACKGROUND: The prison environment can be a difficult environment for nurses to deliver care within, with nurses having to carry out activities that seem to go against their professional role, while at the same time providing care to prisoners who have greater health needs than the general population. There is a lack of theoretical consideration of how prison nurses carry out their role in the face of such challenges...
January 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28212157/current-approaches-to-myopia-control
#15
Seo Wei Leo
PURPOSE OF REVIEW: Myopia is a global problem, being particularly prevalent in the urban areas of east and southeast Asia. In addition to the direct economic and social burdens, associated ocular complications may lead to substantial vision loss. With prevalence of myopia above 80% and high myopia over 20%, it is crucial to control myopia. The aim of this review to is provide an update on the interventions to slow the onset of myopia and retard its progression. RECENT FINDINGS: The epidemic of myopia is characterized by increasingly early onset, combined with high myopia progression rates...
February 15, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28212153/new-therapies-for-the-prevention-and-treatment-of-exacerbations-of-bronchiectasis
#16
Hani Abo-Leyah, James D Chalmers
PURPOSE OF REVIEW: Exacerbations of bronchiectasis have a major impact on quality of life, healthcare costs, and long-term risk of complications. Preventing exacerbations is one of the major goals of treatment. Bronchiectasis is increasingly recognized and the impact of bronchiectasis exacerbations on daily clinical practice is also increasing. RECENT FINDINGS: Preventing bronchiectasis exacerbations are dependent on appropriate risk assessment, identifying the patients at highest risk to rationally target preventive therapies...
February 16, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28212142/honoring-motherhood-the-meaning-of-childbirth-for-tongan-women
#17
Shelly J Reed, Lynn Clark Callister, ʼAna Kavaefiafi, Cheryl Corbett, Debra Edmunds
PURPOSE: The purpose of this ethnographic study was to describe the meaning of childbirth for Tongan women. STUDY DESIGN AND METHODS: In this qualitative descriptive study, 38 Tongan women, 18 from Tonga and 20 from the United States, who had given birth in the past year were invited to share their perceptions of childbirth. Themes were generated collaboratively by the research team. FINDINGS: The overarching theme was honoring motherhood, with other themes including using strength to facilitate an unmedicated vaginal birth, describing the spiritual dimensions of birth, adhering to cultural practices associated with childbearing, and the influence of the concept of respect on childbearing...
February 16, 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28212113/age-and-gender-dependency-of-physiological-networks-in-sleep
#18
Dagmar Krefting, Christoph Jansen, Thomas Penzel, Fang Han, Jan Kantelhardt
Recently, time delay stability analysis of biosignals has been successfully applied as a multivariate time series analysis method to assess the human physiological network in young adults. The degree of connectivity between different network nodes is described by the so-called link strength. Based on polysomnographic recordings (PSGs), it could be shown that the network changes with the sleep stage. Here, we apply the method to a large set of healthy controls spanning six decades of age. As it is well known, that the overall sleep architecture is dependent both on age and on gender, we particularly address the question, if these changes are also found in the network dynamics...
February 17, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28212080/improving-registration-robustness-for-image-guided-liver-surgery-in-a-novel-human-to-phantom-data-framework
#19
Jarrod Collins, Jared Weis, Jon Heiselman, Logan Clements, Amber Simpson, Willam Jarnagin, Michael Miga
In open image-guided liver surgery (IGLS), a sparse representation of the intraoperative organ surface can be acquired to drive image-to-physical registration. We hypothesize that uncharacterized error induced by variation in the collection patterns of organ surface data limits the accuracy and robustness of IGLS registration. Clinical validation of such registration methods is challenged due to the difficulty in obtaining data representative of the true state of organ deformation. We propose a novel human-to-phantom validation framework that transforms surface collection patterns from in vivo IGLS procedures (n=13) onto a well-characterized hepatic deformation phantom for the purpose of validating surface-driven, volumetric nonrigid registration methods...
February 13, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28212003/tip2o7-and-expanded-graphite-nanocomposite-as-anode-material-for-aqueous-lithium-ion-batteries
#20
Yunping Wen, Long Chen, Ying Pang, Zhaowei Guo, Duan Bin, Yong-Gang Wang, Congxiao Wang, Yongyao Xia
This paper reports a facile sol-gel synthesis method to successfully prepare the TiP2O7/expanded graphite (EG) nanocomposite as an advanced anode material for aqueous lithium-ion batteries. The constructed TiP2O7 nanocomposite (50-100 nm) are in-situ encapsulated in the pore and layer structure of expanded graphite with good conductivity and high specific surface area. As a consequence, the resulting TiP2O7/EG electrode exhibits a reversible capacity of 66 mAh g-1 at 0.1 A g-1 with an appropriate potential of -0...
February 17, 2017: ACS Applied Materials & Interfaces
keyword
keyword
20730
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"