keyword
https://read.qxmd.com/read/38493448/single-measurement-of-bowel-wall-thickness-using-intestinal-ultrasonography-in-children-with-ulcerative-colitis
#1
JOURNAL ARTICLE
Masano Otani, Takeru Okuhira, Atsushi Yoden, Emiri Kaji, Keisuke Inoue, Tomoki Aomatsu, Kimitaka Takitani, Akira Ashida
BACKGROUND: Endoscopic monitoring of disease activity in patients with ulcerative colitis (UC) is important. However, frequent colonoscopic examinations are difficult to perform because of their invasiveness, especially in children. Bowel wall thickness (BWT) measurement using intestinal ultrasonography and fecal calprotectin (FC) measurement are useful noninvasive evaluation methods. METHODS: We retrospectively analyzed BWT and FC levels and evaluated the Mayo endoscopic subscore (MES) using colonoscopy in pediatric patients with UC during the same period...
2024: Pediatrics International: Official Journal of the Japan Pediatric Society
https://read.qxmd.com/read/38493445/a-comprehensive-analysis-of-cd47-expression-in-various-histological-subtypes-of-soft-tissue-sarcoma-exploring-novel-opportunities-for-macrophage-directed-treatments
#2
JOURNAL ARTICLE
Iva Benesova, Linda Capkova, Andrej Ozaniak, Pavel Pacas, Katerina Kopeckova, Dominika Galova, Robert Lischke, Tomas Buchler, Zuzana Ozaniak Strizova
PURPOSE: The CD47 molecule, often referred to as the "do not eat me" signal, is frequently overexpressed in tumor cells. This signaling pathway limits phagocytosis by macrophages. Our objective was to determine CD47 abundance in various soft tissue sarcomas (STS) to investigate whether it could serve as a potential evasion mechanism for tumor cells. Additionally, we aimed to assess the prognostic value of CD47 expression by examining its association with different clinicopathological factors...
March 17, 2024: Journal of Cancer Research and Clinical Oncology
https://read.qxmd.com/read/38493401/who-benefits-and-how-five-dimensions-of-adolescent-psychological-well-being-and-their-relative-impact-on-cardiometabolic-health-in-adulthood
#3
JOURNAL ARTICLE
Farah Qureshi, Anne-Josee Guimond, Scott Delaney, Julia K Boehm, Laura D Kubzansky
PURPOSE: Positive dimensions of psychological well-being in adolescence may help youth preserve cardiometabolic health (CMH) as they age, but little is known about which aspects of well-being matter most and for whom. This study examines the differential impact of five dimensions of adolescent psychological well-being on CMH maintenance in adulthood and considers social patterning in both their distribution and respective health benefits. METHODS: Data were from the National Longitudinal Study of Adolescent Health (N = 3,464), five dimensions of psychological well-being were identified at baseline (1994-1995; mean age = 15 years): happiness, optimism, self-esteem, belonging, and feeling loved...
March 14, 2024: Journal of Adolescent Health
https://read.qxmd.com/read/38493397/adolescent-psychiatric-inpatient-episodes-and-subsequent-labor-market-trajectories
#4
JOURNAL ARTICLE
Joonas Pitkänen, Liina Junna, Pekka Martikainen
PURPOSE: Adolescents with psychiatric disorders are known to be more often not in education, employment, or training (NEET) in young adulthood than their peers. However, since most of the available evidence is based on cross-sectional measurement of NEET, there is less evidence on the processes underlying these differences in labor market disadvantage. We assessed these processes by examining transitions between NEET and non-NEET states across young adulthood and the differences in these transitions by adolescent psychiatric inpatient treatment...
March 15, 2024: Journal of Adolescent Health
https://read.qxmd.com/read/38493355/muscle-fibre-typology-affects-whole-body-metabolic-rate-during-isolated-muscle-contractions-and-human-locomotion
#5
JOURNAL ARTICLE
Wannes Swinnen, Eline Lievens, Wouter Hoogkamer, Friedl De Groote, Wim Derave, Benedicte Vanwanseele
The wide variation in muscle fibre type distribution across individuals, along with the very different energy consumption rates in slow versus fast muscle fibres, suggests that muscle fibre typology contributes to inter-individual differences in metabolic rate during exercise. However, this has been hard to demonstrate due to the gap between a single muscle fibre and full-body exercises. We investigated the isolated effect of triceps surae muscle contraction velocity on whole-body metabolic rate during cyclic contractions in individuals a priori selected for their predominantly slow (n = 11) or fast (n = 10) muscle fibre typology by means of proton magnetic resonance spectroscopy (1 H-MRS)...
March 17, 2024: Journal of Physiology
https://read.qxmd.com/read/38493316/management-of-anterior-urethral-stricture-a-survey-of-contemporary-practice-of-iranian-urologists
#6
JOURNAL ARTICLE
Jalil Hosseini, Samin Khannejad, Armin Attar, Ali Goudarzikarim
PURPOSE: To evaluate Iranian urologists' approach to urethral stricture and assess how often they select open urethroplasty over minimally invasive procedures. MATERIAL AND METHODS: This cross-sectional observational study was conducted via www. SURVEY: porsline.ir among members of the Iranian urologists' community. The urologists were contacted via email and social media applications (e.g., WhatsApp, Telegram), and data, including their demographic information and years of practice, as well as questions related to their attitude towards the management of urethral stricture, were collected...
March 17, 2024: Urology Journal
https://read.qxmd.com/read/38493297/differential-feeding-on-ornamental-plants-by-duponchelia-fovealis-lepidoptera-crambidae-larvae
#7
JOURNAL ARTICLE
Sophia M Copeman, Steven D Frank
Duponchelia fovealis (Zeller) (Lepidoptera: Crambidae) is a polyphagous pest that feeds on a variety of ornamental and crop plants. At least 47 plant families have been identified as hosts for D. fovealis in literature based on empirical data and observations. This list is surely incomplete based on the broad feeding habits of D. fovealis. We sought to expand the list of known D. fovealis host plants and to identify species that may be less preferred or not fed upon by D. fovealis. We used laboratory feeding assays to measure D...
March 16, 2024: Environmental Entomology
https://read.qxmd.com/read/38493098/comparison-of-different-trapping-methods-to-collect-malaria-vectors-indoors-and-outdoors-in-western-kenya
#8
JOURNAL ARTICLE
Jackline Kosgei, John E Gimnig, Vincent Moshi, Seline Omondi, Daniel P McDermott, Martin J Donnelly, Collins Ouma, Bernard Abong'o, Eric Ochomo
BACKGROUND: Vector surveillance is among the World Health Organization global vector control response (2017-2030) pillars. Human landing catches are a gold standard but difficult to implement and potentially expose collectors to malaria infection. Other methods like light traps, pyrethrum spray catches and aspiration are less expensive and less risky to collectors. METHODS: Three mosquito sampling methods (UV light traps, CDC light traps and Prokopack aspiration) were evaluated against human landing catches (HLC) in two villages of Rarieda sub-county, Siaya County, Kenya...
March 16, 2024: Malaria Journal
https://read.qxmd.com/read/38493079/the-relationship-between-pregnancy-and-temporomandibular-disorder-tmd-through-diagnostic-criteria-for-temporomandibular-disorders-dc-tmd-axis-ii-evaluation-a-case-control-cross-sectional-study
#9
JOURNAL ARTICLE
Giuseppe Minervini, Maria Maddalena Marrapodi, Marco La Verde, Aida Meto, Yuliia Siurkel, Marco Cicciù, Diana Russo
INTRODUCTION: This study focuses on temporomandibular disorders (TMDs), which affect the temporomandibular joint and related muscles and have multiple causes. Recent studies have examined the connection between menstrual cycles, estrogen levels, and TMDs, but results are inconsistent, highlighting the need for more research. The aim is to explore the prevalence of TMDs in pregnant women and consider how hormonal changes during pregnancy might influence these disorders. METHODS: In this cross-sectional case-control study, we compared 32 pregnant women with 35 non-pregnant women...
March 16, 2024: BMC Oral Health
https://read.qxmd.com/read/38492864/dexamethasone-intracanalicular-insert-for-clinically-significant-aqueous-deficient-dry-eye-a-randomized-controlled-trial
#10
JOURNAL ARTICLE
Michael Lin, Lee Guo, Ian J Saldanha, Shanna VanCourt, Julia Zeng, Sezen Karakus, Michelle Hessen, Gavin Li, Esen K Akpek
PURPOSE: To evaluate a commercially available dexamethasone intracanalicular insert to treat dry eye. DESIGN: Single-center, double-masked, randomized controlled trial. PARTICIPANTS: Patients with clinically significant aqueous-deficient dry eye [combined ocular surface staining score ≥3 (0-12), corneal fluorescein staining ≥2 (0-6), and Schirmer's wetting <10 mm at 5 minutes in both eyes] with symptoms (dryness, eye discomfort, or visual fatigue, ≥30 [0-100]) despite treatment with at least one prescription drop and deemed candidate for topical steroid...
March 14, 2024: Ophthalmology
https://read.qxmd.com/read/38492768/poly-pharmacology-of-existing-drugs-how-to-crack-the-code
#11
REVIEW
Baptiste Mouysset, Marion Le Grand, Luc Camoin, Eddy Pasquier
Drug development in oncology is highly challenging, with less than 5% success rate in clinical trials. This alarming figure points out the need to study in more details the multiple biological effects of drugs in specific contexts. Indeed, the comprehensive assessment of drug poly-pharmacology can provide insights into their therapeutic and adverse effects, to optimize their utilization and maximize the success rate of clinical trials. Recent technological advances have made possible in-depth investigation of drug poly-pharmacology...
March 14, 2024: Cancer Letters
https://read.qxmd.com/read/38492644/assessing-the-risk-of-antimicrobial-resistant-enterococcal-infections-in-humans-due-to-bacitracin-usage-in-poultry
#12
JOURNAL ARTICLE
Randall S Singer, Timothy J Johnson
Bacitracin is an antimicrobial used in the feed or water of poultry in the U.S. for the prevention, treatment, and control of clostridial diseases such as necrotic enteritis. Concern has been raised that bacitracin can select for antimicrobial resistant bacteria that can be transmitted to humans and subsequently cause disease that is more difficult to treat because of the resistance. The objective of the present study was to perform a quantitative risk assessment (QRA) to estimate the potential risk in the U...
March 14, 2024: Journal of Food Protection
https://read.qxmd.com/read/38492607/ecological-consequences-when-organisms-avoid-a-contaminated-environment-a-study-evaluating-the-toxicity-of-fipronil
#13
JOURNAL ARTICLE
Raquel A Moreira, María Pilar González, Mariana A Dias, Allan P Ogura, Freylan Mena, Cassiana C Montagner, Evaldo L G Espíndola, Julián Blasco, Gema Parra, Cristiano V M Araújo
The ability of aquatic organisms to sense the surrounding environment chemically and interpret these signals correctly is crucial to their survival and ecological niche. This study applied the Heterogenous Multi-Habitat Assay System - HeMHAS to evaluate the avoidance potential of Daphnia magna to detect fipronil-contaminated habitats in a connected landscape after a short (48 h), previous, forced exposure to an environmentally relevant concentration of the same insecticide. The swimming of daphnids was also analyzed by recording the total distance covered...
March 14, 2024: Science of the Total Environment
https://read.qxmd.com/read/38492578/effects-of-rare-kidney-diseases-on-kidney-failure-a-longitudinal-analysis-of-the-uk-national-registry-of-rare-kidney-diseases-radar-cohort
#14
JOURNAL ARTICLE
Katie Wong, David Pitcher, Fiona Braddon, Lewis Downward, Retha Steenkamp, Nicholas Annear, Jonathan Barratt, Coralie Bingham, Constantina Chrysochou, Richard J Coward, David Game, Sian Griffin, Matt Hall, Sally Johnson, Durga Kanigicherla, Fiona Karet Frankl, David Kavanagh, Larissa Kerecuk, Eamonn R Maher, Shabbir Moochhala, Jenny Pinney, John A Sayer, Roslyn Simms, Smeeta Sinha, Shalabh Srivastava, Frederick W K Tam, Andrew Neil Turner, Stephen B Walsh, Aoife Waters, Patricia Wilson, Edwin Wong, Christopher Mark Taylor, Dorothea Nitsch, Moin Saleem, Detlef Bockenhauer, Kate Bramham, Daniel P Gale
BACKGROUND: Individuals with rare kidney diseases account for 5-10% of people with chronic kidney disease, but constitute more than 25% of patients receiving kidney replacement therapy. The National Registry of Rare Kidney Diseases (RaDaR) gathers longitudinal data from patients with these conditions, which we used to study disease progression and outcomes of death and kidney failure. METHODS: People aged 0-96 years living with 28 types of rare kidney diseases were recruited from 108 UK renal care facilities...
March 13, 2024: Lancet
https://read.qxmd.com/read/38492498/the-abc-of-mobility
#15
JOURNAL ARTICLE
Rafael Prieto-Curiel, Juan P Ospina
The use of cars in cities has many negative impacts, including pollution, noise and the use of space. Yet, detecting factors that reduce the use of cars is a serious challenge, particularly across different regions. Here, we model the use of various modes of transport in a city by aggregating Active mobility (A), Public Transport (B) and Cars (C), expressing the modal share of a city by its ABC triplet. Data for nearly 800 cities across 61 countries is used to model car use and its relationship with city size and income...
March 2, 2024: Environment International
https://read.qxmd.com/read/38492496/effects-of-radiofrequency-electromagnetic-field-rf-emf-exposure-on-male-fertility-a-systematic-review-of-experimental-studies-on-non-human-mammals-and-human-sperm-in-vitro
#16
JOURNAL ARTICLE
Eugenia Cordelli, Lucia Ardoino, Barbara Benassi, Claudia Consales, Patrizia Eleuteri, Carmela Marino, Maurizio Sciortino, Paola Villani, Martin H Brinkworth, Guangdi Chen, James P McNamee, Andrew W Wood, Lea Belackova, Jos Verbeek, Francesca Pacchierotti
BACKGROUND: The World Health Organization is coordinating an international project aimed at systematically reviewing the evidence regarding the association between radiofrequency electromagnetic field (RF-EMF) exposure and adverse health effects. Reproductive health outcomes have been identified among the priority topics to be addressed. OBJECTIVES: To evaluate the effect of RF-EMF exposure on male fertility of experimental mammals and on human sperm exposed in vitro...
February 19, 2024: Environment International
https://read.qxmd.com/read/38492482/responses-of-vallisneria-natans-and-pistia-stratiotes-to-cu-2-and-mn-2-stress-occurrence-of-caffeic-acid-and-its-degradation-kinetics-during-chlorination
#17
JOURNAL ARTICLE
Xiaoyu Peng, Yonggui Wu, Lixia Chen, Xiao Ma
Macrophytes are crucial in maintaining the equilibrium of aquatic ecosystems. However, the pattern of macrophyte-derived caffeic acid (CA) release under heavy metal stress is yet to be fully understood. More importantly, due to its functional groups, CA may be a precursor to the formation of disinfection by-products, posing threats to water ecology and even safety of human drinking water. This study analyzed the responses of CA released by Vallisneria natans (V. natans) and Pistia stratiotes (P. Stratiotes) when exposed to Cu2+ and Mn2+ stress...
March 15, 2024: Ecotoxicology and Environmental Safety
https://read.qxmd.com/read/38492455/cossif-cosine-similarity-based-image-filtering-to-overcome-low-inter-class-variation-in-synthetic-medical-image-datasets
#18
JOURNAL ARTICLE
Mominul Islam, Hasib Zunair, Nabeel Mohammed
Crafting effective deep learning models for medical image analysis is a complex task, particularly in cases where the medical image dataset lacks significant inter-class variation. This challenge is further aggravated when employing such datasets to generate synthetic images using generative adversarial networks (GANs), as the output of GANs heavily relies on the input data. In this research, we propose a novel filtering algorithm called Cosine Similarity-based Image Filtering (CosSIF). We leverage CosSIF to develop two distinct filtering methods: Filtering Before GAN Training (FBGT) and Filtering After GAN Training (FAGT)...
March 15, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38492419/grazing-alters-the-soil-nematode-communities-in-grasslands-a-meta-analysis
#19
JOURNAL ARTICLE
Zhaokai Sun, Chongzhi Sun, Xin Feng, Tongrui Zhang, Jia Liu, Xinning Wang, Shucheng Li, Shiming Tang, Ke Jin
Grazing causes great disturbances in grassland ecosystems and may change the abundance, diversity, and ecological function of soil biota. Because of their important role in nutrient cycling and as good environmental indicators, nematodes are very representative soil organisms. However, the mechanisms by which grazing intensity, livestock type, duration, and environmental factors (e.g., climate and edaphic factors) affect soil nematodes remain poorly understood. In this study, we collected 1964 paired observations all over the world from 53 studies to clarify the grazing response patterns of soil nematodes and their potential mechanisms...
March 15, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38492350/evaluation-of-treatment-outcomes-and-tolerability-in-older-patients-with-rectal-cancer-treated-with-radiotherapy-accompanied-by-the-g-8-geriatric-score-trod13-003-multicenter-study
#20
JOURNAL ARTICLE
Zeliha Güzelöz, İlknur Bilkay Görken, Barbaros Aydın, Fatma Sert, Deniz Yalman, Murtaza Parvizi, Gülhan Güler Avcı, Pelin Altınok, Hatice Halis, Şefika Arzu Ergen, Züleyha Akgün, Elif Özkan, Yıldız Güney, Didem Karaçetin, Nuri Kaydıhan, Mürsel Düzova, Murat Akın, Bora Uysal, Mihriban Erdoğan, Hülya Ellidokuz, Gamze Aksu, Evrim Metcalfe
INTRODUCTION: The choice of treatment for rectal cancer often differs in older and younger patients, with the rate of radiotherapy use lower among older adults. In our daily practice, when evaluating a frail older patient with rectal cancer, we usually choose to give less treatment. This may be due to concern that the patient will not be able to tolerate radiotherapy. The Geriatric 8 score (G8GS) is a guide to evaluating treatment tolerability as it relates to frailty in older adults with cancer...
March 15, 2024: Journal of Geriatric Oncology
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