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https://www.readbyqxmd.com/read/29332238/normal-variation-in-sagittal-spinal-alignment-parameters-in-adult-patients-an-eos-study-using-serial-imaging
#1
Hwee Weng Dennis Hey, Kian Loong Melvin Tan, Vikaesh Moorthy, Eugene Tze-Chun Lau, Leok-Lim Lau, Gabriel Liu, Hee-Kit Wong
PURPOSE: To describe normal variations in sagittal spinal radiographic parameters over an interval period and establish physiological norms and guidelines for which these images should be interpreted. METHODS: Data were prospectively collected from a continuous series of adult patients with first-episode mild low back pain presenting to a single institution. The sagittal parameters of two serial radiographic images taken 6-months apart were obtained with the EOS® slot scanner...
January 13, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29327730/eosinophil-derived-ccl-6-impairs-hematopoietic-stem-cell-homeostasis
#2
Chao Zhang, Weiwei Yi, Fei Li, Xufei Du, Hu Wang, Ping Wu, Chao Peng, Man Luo, Wen Hua, Catherine Cl Wong, James J Lee, Wen Li, Zhihua Chen, Songmin Ying, Zhenyu Ju, Huahao Shen
Eosinophils (Eos) have been long considered as end-stage effector cells in the hierarchical hematopoietic system. Numerous lines of evidence have suggested that Eos are multifunctional leukocytes with respect to the initiation, propagation and regulation of various inflammatory or immune reactions, especially in allergic diseases. Recent studies have shown that Eos are also required for maintenance of bone marrow plasma cells and differentiation of B cells. However, it remains unclear whether Eos contributes to regulation of hematopoietic stem cell (HSC) homeostasis...
January 12, 2018: Cell Research
https://www.readbyqxmd.com/read/29319661/observed-length-increases-of-magnetically-controlled-growing-rods-are-lower-than-programmed
#3
Sarah E Gilday, Mark S Schwartz, Donita I Bylski-Austrow, David L Glos, Lindsay Schultz, Sara O'Hara, Viral V Jain, Peter F Sturm
BACKGROUND: Magnetically controlled growing rods (MCGRs) are increasingly used in the treatment of early onset scoliosis (EOS). Few studies have reported whether desired lengthening can reliably be achieved, or if prior spine instrumentation and large tissue depths affect lengthening. In this clinical study of EOS patients, it was hypothesized that increases in rod length would equal programmed increases, patients with prior spine instrumentation would lengthen less than patients without prior surgery, and larger tissue depths would decrease lengthening success...
January 9, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29319372/synchronous-application-of-antibiotics-and-essential-oils-dual-mechanisms-of-action-as-a-potential-solution-to-antibiotic-resistance
#4
Lucy Owen, Katie Laird
Antibiotic resistance has increased dramatically in recent years, yet the antibiotic pipeline has stalled. New therapies are therefore needed to continue treating antibiotic resistant infections. One potential strategy currently being explored is the use of non-antibiotic compounds to potentiate the activity of currently employed antibiotics. Many natural products including Essential Oils (EOs) possess broad spectrum antibacterial activity and so have been investigated for this purpose. This article aims to review recent literature concerning the antibacterial activity of EOs and their interactions with antibiotics, with consideration of dual mechanisms of action of EOs and antibiotics as a potential solution to antibiotic resistance...
January 10, 2018: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/29318975/evaluation-of-the-antiproliferative-activity-of-some-nanoparticulate-essential-oils-formulated-in-microemulsion-on-selected-human-carcinoma-cell-lines
#5
Ahmed Abd-Rabou, Amr E Edris
BACKGROUND: Essential oils (EOs) are natural volatile plant extract that have different biological activities including antiproliferative potentials. OBJECTIVE: the current study aims at evaluating the antiproliferative activities of six EOs in their neat state compared to their nanoparticulate form after fabrication in microemulsion against some cancer cell lines. The EOs included marjoram (Origanum majorana), turmeric (Curcuma longa), sweet basil (Ocimum basillicum), clove buds (Syzygium aromaticum), geranium (plargonium graviolenis), and black cumin (Nigella sativa)...
January 10, 2018: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/29316109/a-comparative-study-on-the-photophysics-and-photochemistry-of-xanthene-dyes-in-the-presence-of-pamam-dendrimers
#6
Ernesto Arbeloa, Carlos Mario Previtali, Sonia Graciela Bertolotti
The photophysical and photochemical properties of the xanthene dyes Eosin-Y (Eos), Erythrosin-B (Ery) and Rose Bengal (RB) were evaluated in the presence of amino-terminated polyamido-amine (PAMAM) dendrimers of relatively high generations (G3-G5), in alkaline aqueous solution. UV-Vis absorption and fluorescence spectra of the dyes showed bathochromic shifts, which correlated with the size of the dendrimer. From absorption data binding constant (Kbind) were calculated. High Kbind values resulted, indicating a strong interaction between both molecules...
January 7, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/29315128/parallel-proximal-fixation-in-rib-based-growing-rod-system-a-novel-approach-to-deal-with-proximal-anchor-migration
#7
John Heflin, Michelle Welborn, Norman Ramirez-Lluch, Ivan Iriarte, Ron El-Hawary, Graham T Fedorak, John T Smith
STUDY DESIGN: Retrospective case control OBJECTIVE.: To report on differences in implant failure rates and complications requiring reoperation in children with early-onset scoliosis (EOS) treated with rib-based distraction utilizing four proximal fixation points in either a parallel or in-line configuration. SUMMARY OF BACKGROUND DATA: Proximal anchor failure continues to be a significant problem in growth-friendly surgery using rib-based distraction to treat children with EOS...
January 8, 2018: Spine
https://www.readbyqxmd.com/read/29310921/does-patients-perception-of-leg-length-after-total-hip-arthroplasty-correlate-with-anatomical-leg-length
#8
Jean Y Lazennec, Dominique Folinais, Caroline Florequin, Aidin E Pour
BACKGROUND: This study assessed the correlation among the patients' perception of the leg length discrepancy (LLD) after total hip arthroplasty (THA) and the anatomical and functional leg length, pelvic and knee alignments, and foot height. METHODS: Patients without significant spinal pathology or previous spine or lower extremity surgery who underwent primary THA (101 patients) were evaluated using EOS images obtained in standing position. All 3-dimensional measures were evaluated and compared for the repeatability and reproducibility and correlation with patients' perception of leg length...
December 13, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29304179/thymus-mastichina-l-essential-oils-from-murcia-spain-composition-and-antioxidant-antienzymatic-and-antimicrobial-bioactivities
#9
Ana-Belen Cutillas, Alejandro Carrasco, Ramiro Martinez-Gutierrez, Virginia Tomas, Jose Tudela
The compositions of essential oils (EOs) from Spanish marjoram (Thymus mastichina L.) grown in several bioclimatic zones of Murcia (SE Spain) were studied to determine their absolute and relative concentrations using gas chromatography-mass spectrometry. 1,8-Cineole and linalool were the main components, followed by α-pinene, β-pinene and α-terpineol. (-)-Linalool, (+)-α-terpineol and (+)-α-pinene were the most abundant enantiomers. When the antioxidant capacities of T. mastichina EOs and their compounds were measured by five methods, EOs and linalool, linalyl acetate, α-terpinene and γ-terpinene, among others, showed antioxidant activities...
2018: PloS One
https://www.readbyqxmd.com/read/29299680/validation-study-of-the-early-onset-schizophrenia-diagnosis-in-the-danish-psychiatric-central-research-register
#10
Ditte Lammers Vernal, Anne Dorte Stenstrøm, Nina Staal, Anne Marie Raabjerg Christensen, Christine Ebbesen, Anne Katrine Pagsberg, Christoph U Correll, René Ernst Nielsen, Marlene Briciet Lauritsen
The objective of this study is to assess (1) the concordance and validity of schizophrenia register diagnoses among children and adolescents (early onset schizophrenia = EOS) in the Danish Psychiatric Central Research Register (DPCRR), and (2) the validity of clinical record schizophrenia diagnoses. Psychiatric records from 200 patients with a first-time diagnosis of schizophrenia (F20.x) at age < 18 years between 1994 and 2009 in the DPCRR were rated by experienced clinicians according to ICD-10 criteria, using a predefined checklist...
January 3, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29295521/molecular-targets-for-components-of-essential-oils-in-the-insect-nervous-system-a-review
#11
REVIEW
Milena Jankowska, Justyna Rogalska, Joanna Wyszkowska, Maria Stankiewicz
Essential oils (EOs) are lipophilic secondary metabolites obtained from plants; terpenoids represent the main components of them. A lot of studies showed neurotoxic actions of EOs. In insects, they cause paralysis followed by death. This feature let us consider components of EOs as potential bioinsecticides. The inhibition of acetylcholinesterase (AChE) is the one of the most investigated mechanisms of action in EOs. However, EOs are rather weak inhibitors of AChE. Another proposed mechanism of EO action is a positive allosteric modulation of GABA receptors (GABArs)...
December 23, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29288755/essential-oil-of-citrus-lumia-risso-phytochemical-profile-antioxidant-properties-and-activity-on-the-central-nervous-system
#12
Antonella Smeriglio, Susanna Alloisio, Francesco Maria Raimondo, Marcella Denaro, Jianbo Xiao, Laura Cornara, Domenico Trombetta
The use of essential oils (EOs) is known since long time in traditional medicine and aromatherapy for the management of various oxidative stress-related disorders and has been further increased recently for their neuroprotective and anti-aging potentials as well as for reducing anxiety and stress. The purpose of this work was to evaluate, for the first time, the chemical composition of Citrus lumia Risso EO and its antioxidant, anti-cholinesterase, and neuroactive properties by cell-free and cell-based assays...
December 27, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29287816/comparison-of-percentile-weight-gain-of-growth-friendly-constructs-in-early-onset-scoliosis
#13
Liam R Harris, Lindsay M Andras, Paul D Sponseller, Charles E Johnston, John B Emans, David L Skaggs
STUDY DESIGN: Multicenter retrospective cohort. OBJECTIVE: To compare improvement in nutritional status seen in early-onset scoliosis (EOS) patients following treatment with various growth-friendly techniques, especially in underweight patients (<20th weight percentile). BACKGROUND: Thoracic insufficiency resulting from EOS can lead to severe cardiopulmonary disease. In this age group, pulmonary function tests are often difficult or impossible to perform...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29287758/repellence-of-essential-oils-and-selected-compounds-against-ticks-a-systematic-review
#14
REVIEW
Giovanni Benelli, Roman Pavela
Ticks act as vectors of a wide range of infectious agents, far encompassing any other group of bloodsucking arthropods worldwide. The prevention of tick-borne diseases is strictly linked to the successful management of tick vector populations. The employ of repellents can represent a worth solution to avoid tick bites. It is widely adopted to protect travellers and pets exposed to ticks during limited periods of the year. The use of natural products as active ingredients in eco-friendly repellent formulations is currently a prominent research area, due to the wide diversity and high effectiveness of a number of plant-borne compounds, with special reference to essential oils (EOs) extracted from medicinal and aromatic species...
December 26, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29285943/-assessment-of-sacroiliacal-joint-mobility-in-patients-with-low-back-pain
#15
Máté Burkus, István Márkus, Bálint Niklai, Miklós Tunyogi-Csapó
INTRODUCTION: Sagittal alignment of the pelvis is typically characterized using three fundamental parameters. Among these, pelvic incidence is traditionally considered to be anatomically 'constant'. AIM: We aimed to analyze the pelvic parameters of low back pain patients with suspected sacroiliac joint laxity. METHOD: Pelvic parameters were assessed in standing and seated EOS 2D/3D radiographs of 48 cases of persistent low back pain, and compared to upper body position using cluster analysis and t-test...
December 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29284278/implementation-and-evaluation-of-the-early-onset-sepsis-risk-calculator-in-a-high-risk-university-nursery
#16
Jessica B Beavers, Shasha Bai, Jennifer Perry, Jordan Simpson, Sara Peeples
There is growing interest in the Kaiser early-onset sepsis (EOS) risk calculator though institutions are hesitant to deviate from the Centers for Disease Control and Prevention guidelines and implement this in their hospitals. We describe the process of implementing routine use of the risk calculator in term and late preterm newborns delivered to mothers with chorioamnionitis in a level III neonatal intensive care unit (NICU). A retrospective chart review of infants delivered to mothers with chorioamnionitis from 2011 to 2014 was performed...
December 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/29278858/the-ikaros-family-in-lymphocyte-development
#17
REVIEW
Beate Heizmann, Philippe Kastner, Susan Chan
The IKZF family of transcription factors are essential regulators of lymphopoiesis. Ikaros, Helios, Aiolos and Eos function as transcriptional repressors and activators during T and B cell differentiation and in mature cell function, depending on the stage of development and/or cell type. Their potential mechanisms of action are varied. Ikaros family proteins partner with multiple complexes, including NuRD, PRC2 and transcription elongation factors, to modulate gene expression and the chromatin state. In humans, mutations in the IKZF genes are associated with B cell deficiency, leukemias and autoimmunity...
December 23, 2017: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29275925/utility-of-early-onset-sepsis-risk-calculator-for-neonates-born-to-mothers-with-chorioamnionitis
#18
David Carola, Mansi Vasconcellos, Amy Sloane, Dorothy McElwee, Caroline Edwards, Jay Greenspan, Zubair H Aghai
OBJECTIVES: To evaluate the performance of the early-onset sepsis (EOS) risk calculator in a cohort of neonates born to mothers with clinical chorioamnionitis, and to compare the diagnostic utility of the EOS calculator, clinical signs, and laboratory evaluations for correctly identifying EOS in this cohort. STUDY DESIGN: This was a retrospective study of neonates born at ≥35 weeks of gestation to mothers with chorioamnionitis. The risk and management categories for all neonates were calculated using the EOS calculator, and these results were analyzed and compared with laboratory data and clinical signs...
December 22, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29273064/the-asian-fish-tapeworm-schyzocotyle-acheilognathi-is-widespread-in-baitfish-retail-stores%C3%A2-in-michigan-usa
#19
Traimat Boonthai, Seth J Herbst, Gary E Whelan, Michelle Gunn Van Deuren, Thomas P Loch, Mohamed Faisal
BACKGROUND: The Asian fish tapeworm Schyzocotyle acheilognathi (Yamaguti, 1934) is an important fish pathogen because of its wide range of intermediate and definitive hosts and its pathological consequences. This study was designed to determine if baitfish are a likely vector contributing to the expansion of the invasive Asian fish tapeworm. RESULTS: We collected live baitfish for examination from 78 retail stores in Michigan between September 2015 and June 2016...
December 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29273038/anti-stress-and-neuronal-cell-differentiation-induction-effects-of-rosmarinus-officinalis-l-essential-oil
#20
Myra O Villareal, Ayumi Ikeya, Kazunori Sasaki, Abdelkarim Ben Arfa, Mohamed Neffati, Hiroko Isoda
BACKGROUND: Mood disorder accounts for 13 % of global disease burden. And while therapeutic agents are available, usually orally administered, most have unwanted side effects, and thus making the inhalation of essential oils (EOs) an attractive alternative therapy. Rosmarinus officinalis EO (ROEO), Mediterranean ROEO reported to improve cognition, mood, and memory, the effect on stress of which has not yet been determined. Here, the anti-stress effect of ROEO on stress was evaluated in vivo and in vitro...
December 22, 2017: BMC Complementary and Alternative Medicine
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