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https://www.readbyqxmd.com/read/28108852/missing-the-target-the-neural-processing-underlying-the-omission-error
#1
Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
The omissions are infrequent errors consisting in missing responses to the target stimuli. This is the first study aimed at investigating the brain activities associated with omissions in a decision-making task. We recorded event-related potentials (ERPs) in 12 subjects which reported a suitable number of omissions in a visual go/no-go task. We investigated both the pre- and post-stimulus brain activities associated with correct and omitted trials. The electrical neuroimaging technique (BESA) was adopted to extract the anterior insula (aIns) activity associated with the prefrontal P2 component (pP2) peaking about 300 ms after the stimulus and reflecting the stimulus-response mapping process...
January 20, 2017: Brain Topography
https://www.readbyqxmd.com/read/28108415/how-does-mindfulness-modulate-self-regulation-in-pre-adolescent-children-an-integrative-neurocognitive-review
#2
REVIEW
Rebekah Jane Kaunhoven, Dusana Dorjee
Pre-adolescence is a key developmental period in which complex intrinsic volitional methods of self-regulation are acquired as a result of rapid maturation within the brain networks underlying the self-regulatory processes of attention control and emotion regulation. Fostering adaptive self-regulation skills during this stage of development has strong implications for physical health, emotional and socio-economic outcomes during adulthood. There is a growing interest in mindfulness-based programmes for pre-adolescents with initial findings suggesting self-regulation improvements, however, neurodevelopmental studies on mindfulness with pre-adolescents are scarce...
January 17, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28107964/development-and-validation-of-a-multi-residue-method-for-the-analysis-of-brominated-and-organophosphate-flame-retardants-in-indoor-dust
#3
Chang He, Xianyu Wang, Phong Thai, Jochen F Mueller, Christie Gallen, Yan Li, Christine Baduel
Flame retardants are associated to numerous adverse health effects, can accumulate in humans and have been used intensively worldwide. Recently, dust has been identified as a major human exposure route for flame retardants. The aim of this study was to develop a multi-residue method using a two-step SPE purification. It enabled us to effectively limit co-extracted matrix/interferets and therefore a simultaneous analysis of brominated and organophosphate flame retardants for indoor dust was achieved. The optimized method was validated according to standard protocol and achieved good accuracy and reproducibility (percent error ranged from -29% to 28%)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107896/cortisol-levels-in-hair-are-altered-in-irritable-bowel-syndrome-a-case-control-study-in-primary-care
#4
A-K Norlin, S Walter, E Theodorsson, V Tegelstrom, E Grodzinsky, M P Jones, Å Faresjö
OBJECTIVE: Stress is an important component in the pathophysiology of irritable bowel syndrome (IBS). Long term Hypothalamus Pituitary Adrenal (HPA)-axis activity can be studied by measuring hair cortisol concentrations (HCC). Some previous studies have indicated a dysregulated HPA-axis in IBS patients, but cortisol levels in hair have not yet been studied. We investigated whether HCC and self-reported stress differentiate IBS patients from controls. METHODS: In a cross-sectional study within 10 Swedish Primary Health Care Centers we compared patients in working age with active IBS to patients without GI complaints...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107594/weighing-the-evidence-from-surgical-trials
#5
Quoc-Dien Trinh, Alexander P Cole, Prokar Dasgupta
With growing calls to improve value in health care, the assessment of surgical outcomes has moved to the spotlight. Public awareness of medical errors has spurred initiatives like the ProPublica "Surgeon Scorecard" to measure and report complications (h t t p s : //projects. propublica. org/surgeons/). High-tech and expensive innovations such as robot-assisted surgery must be measured against traditional approaches. This article is protected by copyright. All rights reserved.
January 20, 2017: BJU International
https://www.readbyqxmd.com/read/28107395/prevalence-of-pre-analytical-errors-in-clinical-chemistry-diagnostic-labs-in-sulaimani-city-of-iraqi-kurdistan
#6
Dereen Najat
BACKGROUND: Laboratory testing is roughly divided into three phases: a pre-analytical phase, an analytical phase and a post-analytical phase. Most analytical errors have been attributed to the analytical phase. However, recent studies have shown that up to 70% of analytical errors reflect the pre-analytical phase. The pre-analytical phase comprises all processes from the time a laboratory request is made by a physician until the specimen is analyzed at the lab. Generally, the pre-analytical phase includes patient preparation, specimen transportation, specimen collection and storage...
2017: PloS One
https://www.readbyqxmd.com/read/28106729/comparison-of-orbit-based-and-time-offset-based-geometric-correction-models-for-sar-satellite-imagery-based-on-error-simulation
#7
Seunghwan Hong, Yoonjo Choi, Ilsuk Park, Hong-Gyoo Sohn
Geometric correction of SAR satellite imagery is the process to adjust the model parameters that define the relationship between ground and image coordinates. To achieve sub-pixel geolocation accuracy, the adoption of the appropriate geometric correction model and parameters is important. Until now, various geometric correction models have been developed and applied. However, it is still difficult for general users to adopt a suitable geometric correction models having sufficient precision. In this regard, this paper evaluated the orbit-based and time-offset-based models with an error simulation...
January 17, 2017: Sensors
https://www.readbyqxmd.com/read/28106234/improving-patient-assessed-outcomes-after-cataract-surgery
#8
Behrad Samadi, Mats Lundström, Maria Kugelberg
PURPOSE: To identify and evaluate possible causes of poor patient-reported visual function after cataract surgery. METHODS: We obtained retrospective data from the Swedish National Cataract Register on patient self-assessed visual function before and after cataract surgery based on the Catquest-9SF questionnaire. We identified patients who self-reported similar or more difficulties postoperatively than preoperatively, and looked at possible causative variables such as sex, age, preoperative and postoperative corrected distance visual acuity (CDVA) and refractive errors, and ocular comorbidity...
January 3, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28105886/interobserver-delineation-uncertainty-in-involved-node-radiation-therapy-inrt-for-early-stage-hodgkin-lymphoma-on-behalf-of-the-radiotherapy-committee-of-the-eortc-lymphoma-group
#9
Marianne C Aznar, Theodore Girinsky, Anne Kiil Berthelsen, Berthe Aleman, Max Beijert, Martin Hutchings, Yolande Lievens, Paul Meijnders, Peter Meidahl Petersen, Deborah Schut, Maja V Maraldo, Richard van der Maazen, Lena Specht
BACKGROUND AND PURPOSE: In early-stage classical Hodgkin lymphoma (HL) the target volume nowadays consists of the volume of the originally involved nodes. Delineation of this volume on a post-chemotherapy CT-scan is challenging. We report on the interobserver variability in target volume definition and its impact on resulting treatment plans. MATERIALS AND METHODS: Two representative cases were selected (1: male, stage IB, localization: left axilla; 2: female, stage IIB, localizations: mediastinum and bilateral neck)...
January 20, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28105649/reanalysis-of-korean-war-anthropological-records-to-support-the-resolution-of-cold-cases
#10
Emily K Wilson
Re-investigation of previously unidentified remains from the Korean War has yielded 55 new identifications, each with corresponding records of prior anthropological analyses. This study compares biological assessments for age at death, stature, and ancestry across (i) anthropological analyses from the 1950s, (ii) recent anthropological analyses of those same sets of remains, and (iii) the reported antemortem biological information for the identified individual. A comparison of long bone measurements from both the 1950s and during reanalysis is also presented...
January 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28105145/stem-cell-transplantation-during-cancer
#11
Xiao-Ying Zhang, Pei-Ying Zhang
Hematological malignancies account for approximately 9.5% of new cancers diagnosed annually. Lymphoma is the most frequent of all known categories of hematological malignancies. Worldwide, extensive research has focused on this type of cancer. However, new treatments are investigated in various clinical as well as pre-clinical studies. Hematopoietic stem cell transplantation (HSCT) is a recent and upcoming treatment strategy for patients with hematopoietic malignancies and inborn errors of metabolism or immune deficiencies...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28103971/-surgical-treatment-of-small-pulmonary-nodules-under-video-assisted-thoracoscopy-%C3%A2-a-report-of-129-cases
#12
Tong Wang, Tiansheng Yan, Feng Wan, Shaohua Ma, Keyi Wang, Jingdi Wang, Jintao Song, Wei He, Jie Bai, Liang Jin
BACKGROUND: The development of image technology has led to increasing detection of pulmonary small nodules year by year, but the determination of their nature before operation is difficult. This clinical study aimed to investigate the necessity and feasibility of surgical resection of pulmonary small nodules through a minimally invasive approach and the operational manner of non-small cell lung cancer (NSCLC). METHODS: The clinical data of 129 cases with pulmonary small nodule of 10 mm or less in diameter were retrospectively analyzed in our hospital from December 2013 to November 2016...
January 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28103770/integrating-multiple-receptor-conformation-docking-and-multi-dimensional-qsar-for-enhancing-accuracy-of-binding-affinity-prediction
#13
Vangala Radhika, Hassan Araimsh Jaraf, Sivan Sree Kanth, Manga Vijjulatha
BACKGROUND: The accuracy of molecular conformation for Quantitative Structure Activity Relationship (QSAR) studies is an important criteria, and the most favourable bioactive conformer selection is a tough task. Correct ligand alignment as input for 3D-QSAR is an important step that is prone to human biases. Multiple-dimensional QSAR (mQSAR) approach provides a promising alternative to classic 3D-QSAR for drug discovery purposes. OBJECTIVE: Obtaining ligand conformations from multiple receptor conformation docking (MRCD) will reduce the margin of error by incorporating the receptor based alignment of ligand conformations...
January 19, 2017: Current Computer-aided Drug Design
https://www.readbyqxmd.com/read/28103568/on-the-exploration-of-information-from-the-dtw-cost-matrix-for-online-signature-verification
#14
Abhishek Sharma, Suresh Sundaram
This paper explores the utility of information derived from the dynamic time warping (DTW) cost matrix for the problem of online signature verification. The prior works in literature primarily utilize only the DTW scores to authenticate a test signature. To the best of our knowledge, the characteristics of the warping path (used for the alignment) in the cost matrix is hardly exploited for verification of online signatures. Accordingly, we devise a score that utilizes the information from the cost matrix and warping path alignments...
January 17, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28103387/self-administered-health-literacy-instruments-for-people-with-diabetes-systematic-review-of-measurement-properties
#15
REVIEW
Eun-Hyun Lee, Chun-Ja Kim, Jiyeon Lee, Seung Hei Moon
AIMS: The aims of this study were to identify all available self-administered instruments measuring health literacy in people with diabetes and to determine the current instrument that is the most appropriate for applying to this population in both practice and research. DESIGN: A systematic review of measurement properties. DATA SOURCES: MEDLINE, EMBASE and CINAHL electronic databases from their inception up to 28 March 28 2016. REVIEW METHOD: The methodological quality of each included study was assessed using the COnsensus-based Standards for the selection of health Measurement INstruments checklist...
January 19, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28102971/how-is-physical-activity-measured-in-lung-cancer-a-systematic-review-of-outcome-measures-and-their-psychometric-properties
#16
REVIEW
Lara Edbrooke, Linda Denehy, Selina M Parry, Ronan Astin, Sandy Jack, Catherine L Granger
Physical activity (PA) levels are low in patients with lung cancer. Emerging evidence supports the use of interventions to increase PA in this population. We aimed to (1) identify and synthesize outcome measures which assess PA levels in patients with lung cancer and (2) to evaluate, synthesize and compare the psychometric properties of these measures. A systematic review of articles from searches was conducted of five electronic databases and personal records. Eligible studies were those which assessed PA using either performance-based or patient-reported measures...
February 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28102868/control-and-automation-of-multilayered-integrated-microfluidic-device-fabrication
#17
Sarit Kipper, Ludmila Frolov, Ortal Guy, Michal Pellach, Yair Glick, Asaf Malichi, Binyamin A Knisbacher, Efrat Barbiro-Michaely, Dorit Avrahami, Yehuda Yavets-Chen, Erez Y Levanon, Doron Gerber
Integrated microfluidics is a sophisticated three-dimensional (multi layer) solution for high complexity serial or parallel processes. Fabrication of integrated microfluidic devices requires soft lithography and the stacking of thin-patterned PDMS layers. Precise layer alignment and bonding is crucial. There are no previously reported standards for alignment of the layers, which is mostly performed using uncontrolled processes with very low alignment success. As a result, integrated microfluidics is mostly used in academia rather than in the many potential industrial applications...
January 19, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28102073/estimates-of-health-impacts-and-radiative-forcing-in-winter-haze-in-eastern-china-through-constraints-of-surface-pm2-5-predictions
#18
Meng Gao, Pablo E Saide, Jinyuan Xin, Yuesi Wang, Zirui Liu, Yuxuan Wang, Zifa Wang, Mariusz Pagowski, Sarath K Guttikunda, Gregory R Carmichael
The Gridpoint Statistical Interpolation (GSI) Three-Dimensional Variational (3DVAR) data assimilation system is extended to treat the MOSAIC aerosol model in WRF-Chem, and to be capable of assimilating surface PM2.5 concentrations. The coupled GSI-WRF-Chem system is applied to reproduce aerosol levels over China during an extremely polluted winter month, January 2013. After assimilating surface PM2.5 concentrations, the correlation coefficients between observations and model results averaged over the assimilated sites are improved from 0...
January 19, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28101403/quantitative-assessment-of-hemodynamic-and-structural-characteristics-of-in-vivo-brain-tissue-using-total-diffuse-reflectance-spectrum-measured-in-a-non-contact-fashion
#19
Yinchen Song, Sarahy Garcia, Yisel Frometa, Jessica C Ramella-Roman, Mohammad Soltani, Mohamed Almadi, Jorge J Riera, Wei-Chiang Lin
Here we present a new methodology that investigates the intrinsic structural and hemodynamic characteristics of in vivo brain tissue, in a non-contact fashion, and can be easily incorporated in an intra-operative environment. Within this methodology, relative total diffuse reflectance spectra (RTD(λ)) were acquired from targets using a hybrid spectroscopy imaging system. A spectral interpretation algorithm was subsequently applied to RTD(λ) to retrieve optical properties related to the compositional and structural characteristics of each target...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28099286/multicenter-study-validating-accuracy-of-a-continuous-respiratory-rate-measurement-derived-from-pulse-oximetry-a-comparison-with-capnography
#20
Sergio D Bergese, Michael L Mestek, Scott D Kelley, Robert McIntyre, Alberto A Uribe, Rakesh Sethi, James N Watson, Paul S Addison
BACKGROUND: Intermittent measurement of respiratory rate via observation is routine in many patient care settings. This approach has several inherent limitations that diminish the clinical utility of these measurements because it is intermittent, susceptible to human error, and requires clinical resources. As an alternative, a software application that derives continuous respiratory rate measurement from a standard pulse oximeter has been developed. We sought to determine the performance characteristics of this new technology by comparison with clinician-reviewed capnography waveforms in both healthy subjects and hospitalized patients in a low-acuity care setting...
January 17, 2017: Anesthesia and Analgesia
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