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"Conflict of interest"

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https://www.readbyqxmd.com/read/28721052/study-of-the-combinatorial-impact-of-empathy-and-emotion-on-the-processing-of-conflicts-of-interest-with-the-event-related-potential-technique
#1
Xiaoli He, Ni Zhang
OBJECTIVES: Studies have found that empathy is important in moral development and violence suppression, and emotion also affects empathy. However, the combinatorial effect of emotion and empathy on the processing of conflicts is not known. MATERIALS AND METHODS: A total of 44 undergraduate students (23 in low-empathy group and 21 in high-empathy group) were enrolled in this study. They were subjected to positive, negative, and neutral emotion evoking, as well as conflicting or nonconflicting proposals...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28716636/a-simplified-clinical-prediction-rule-for-prognosticating-independent-walking-after-spinal-cord-injury-a-prospective-study-from-a-canadian-multicenter-spinal-cord-injury-registry
#2
Katharine E Hicks, Yichen Zhao, Nader Fallah, Carly Rivers, Vanessa Noonan, Tova Plashkes, Eugene K Wai, Darren M Roffey, Eve Tsai, Jerome Paquet, Najmedden Attabib, Travis Marion, Henry Ahn, Philippe Phan
BACKGROUND: Context: Traumatic spinal cord injury (SCI) is a debilitating condition with limited treatment options for neurological or functional recovery. The ability to predict the prognosis of walking post-injury with emerging prediction models could aid in rehabilitation strategies and reintegration into the community. PURPOSE: To re-validate an existing clinical prediction model for independent ambulation (van Middendorp et al. 2011) utilising acute and long-term post-injury follow-up data, and to investigate the accuracy of a simplified model using prospectively collected data from a Canadian multicenter SCI database, the Rick Hansen Spinal Cord Injury Registry (RHSCIR)...
July 14, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28710807/conflicts-of-interest-in-laboratory-hematology
#3
EDITORIAL
T I George
No abstract text is available yet for this article.
August 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28705922/the-cochrane-collaboration-withdraws-a-review-on-methylphenidate-for-adults-with-attention-deficit-hyperactivity-disorder
#4
Kim Boesen, Luis Carlos Saiz, Juan Erviti, Ole Jakob Storebø, Christian Gluud, Peter C Gøtzsche, Karsten Juhl Jørgensen
A Cochrane systematic review on immediate-release methylphenidate for adults with attention deficit hyperactivity disorder (ADHD) was withdrawn from the Cochrane Library on 26 May 2016 after substantial criticism of its methods and flawed conclusions. Retraction of scientific papers on this basis is unusual but can be necessary. We provide a summary of the criticism that led to the withdrawal. We detail the methodological flaws of the withdrawn Cochrane systematic review and general issues of bias and shortcomings of the included ADHD trials: cross-over designs compared with parallel-group designs, exclusion of participants with psychiatric comorbidity, absence of 'functional outcomes' and use of clinical outcomes with limited relevance, short trial duration and small trial populations, broken blinding caused by easily recognisable side effects, combining outcome assessments by trial investigators and participants, outcome reporting bias, poor evaluation of cardiovascular and psychiatric harms and conflicts of interest of trialists and systematic reviewers...
July 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28705774/asia-a-sensory-and-motor-complete-is-not-different-than-asia-b-sensory-incomplete-motor-complete-in-gunshot-related-spinal-cord-injury
#5
Eric McCoy, Nima Eftekhary, Kenneth Nwosu, Dudley Fukunaga, Charles Liu, Kevin Rolfe
Background Context We receive a large number of spinal cord injury (SCI) patients due to penetrating gunshot wounds (GSW) at our national rehabilitation center. Though many patients are labeled American Spinal Injury Association (ASIA) B sensory incomplete due to sensory sparing, especially deep anal pressure, with purported prognostic value, we have not observed a clinical difference from ASIA A completes. We hypothesized that sensory sparing, if meaningful, should reduce the occurrence of pressure ulcers...
July 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28700443/assessment-of-conflicts-of-interest-in-robotic-surgical-studies-validating-author-s-declarations-with-the-open-payments-database
#6
Sunil V Patel, David Yu, Basheer Elsolh, Ben M Goldacre, Garrett M Nash
BACKGROUND: Accurate conflict of interest (COI) statements are important, as a known COI may invalidate study results due to the potential risk of bias. OBJECTIVE: To determine the accuracy of self-declared COI statements in robotic studies and identify risk factors for undeclared payments. METHODS: Robotic surgery studies were identified through EMBASE and MEDLINE and included if published in 2015 and had at least one American author. Undeclared COI were determined by comparing the author's declared COI with industry reported payments found in the "Open Payments" database for 2013 and 2014...
July 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28693566/medical-student-and-medical-school-teaching-faculty-perceptions-of-conflict-of-interest
#7
Nicholas S Andresen, Tyler S Olson, Matthew D Krasowski
BACKGROUND: Attitudes towards conflict of interest (COI) and COI policy are shaped during medical school and influence both the education of medical students and their future medical practice. Understanding the current attitudes of medical students and medical school teaching faculty may provide insight into what is taught about COI and COI policy within the 'hidden' medical curriculum. Differences between medical student and medical school teaching faculty perceptions of COI and COI policy have not been compared in detail...
July 11, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28688200/conflicts-of-interest-in-emergency-medicine
#8
Joel Martin Geiderman, Kenneth V Iserson, Catherine A Marco, John Jesus, Arvind Venkat
Conflicts of interest are common in the practice of emergency medicine and may be present in the areas of clinical practice, relations with industry, expert witness testimony, medical education, research, and organizations. A conflict of interest occurs when there is dissonance between a primary interest and another interest. The concept of professionalism in medicine places the patient as the primary interest in any interaction with a physician. We contend that patient welfare is the ultimate interest in the entire enterprise of medicine...
July 8, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28687832/addressing-the-challenges-in-tonsillectomy-research-to-inform-health-care-policy-a-review
#9
Rishi Mandavia, Anne G M Schilder, Panagiotis A Dimitriadis, Elias Mossialos
Importance: Eighty-five percent of investment in medical research has been wasted, with lack of effect on clinical practice and policy. There is increasing effort to improve the likelihood of research being used to influence clinical practice and policy. Tonsillectomy is one of the most common otorhinolaryngologic surgical procedures, and its frequency, cost, and morbidity create a clear need for evidence-based guidelines and policy. The first systematic review on tonsillectomy was conducted 40 years ago and highlighted the lack of definitive evidence for the procedure...
July 6, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28687825/conflict-of-interest-conflicting-interests-and-effective-collaboration-between-academia-and-industry-on-preclinical-and-clinical-cancer-research
#10
Mace L Rothenberg, David H Johnson
No abstract text is available yet for this article.
July 6, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28680446/donor-selection-for-allogenic-hemopoietic-stem-cell-transplantation-clinical-and-ethical-considerations
#11
REVIEW
Irene Riezzo, Natascha Pascale, Raffaele La Russa, Arcangelo Liso, Monica Salerno, Emanuela Turillazzi
Allogenic hematopoietic progenitor cell transplantation (allo-HSCT) is an established treatment for many diseases. Stem cells may be obtained from different sources: mobilized peripheral blood stem cells, bone marrow, and umbilical cord blood. The progress in transplantation procedures, the establishment of experienced transplant centres, and the creation of unrelated adult donor registries and cord blood banks gave those without an human leucocyte antigen- (HLA-) identical sibling donor the opportunity to find a donor and cord blood units worldwide...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28677563/misunderstandings-mandatory-biopsies-and-conflicts-of-interests-in-clinical-trials-a-coercive-cocktail
#12
Catriona M McNeil, Martin H N Tattersall
No abstract text is available yet for this article.
July 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28677312/conflicts-of-interest-in-medicine-taking-diversity-seriously
#13
Jane Williams, Christopher Mayes, Paul Komesaroff, Ian Kerridge, Wendy Lipworth
Conflicts of interest (COI) are considered ubiquitous in many healthcare arrangements,(1) but there is disagreement on how COI should be defined, whether non-financial conflicts deserve attention and the relationship between COI and harm. We conducted a study of Australian healthcare professionals and students to gain a better understanding of the way that COI are understood in practice. In this paper, we outline an empirically derived taxonomy of the understanding of, and attitudes towards, COI. We carried out 25 semistructured interviews with clinicians working in several fields across Australia and held six focus group discussions with medical students in New South Wales...
July 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28675422/reviving-cochrane-s-contribution-to-evidence-based-medicine-bridging-the-gap-between-evidence-of-efficacy-and-evidence-of-effectiveness-and-cost-effectiveness
#14
Jack E James
Evidence-based medicine (EBM) has been widely adopted as the main means for transforming medical practice informed by individual practitioner experience to that informed by science. Yet, as a movement for comprehensive change, EBM has not been as transformative as had been widely anticipated. Evidence of clinical efficacy is often organized hierarchically with the randomized controlled trial located towards the apex of an imaginary pyramid. This familiar hierarchy of evidence in medical education, practice, and science serves to guide evaluations of the internal validity of randomized controlled trials, thereby establishing the "efficacy" of clinical interventions...
July 4, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28673831/risk-factors-for-laryngeal-penetration-aspiration-in-patients-with-acute-traumatic-cervical-spinal-cord-injury
#15
Tiina Ihalainen, Irina Rinta-Kiikka, Teemu M Luoto, Tuomo Thesleff, Mika Helminen, Anna-Maija Korpijaakko-Huuhka, Antti Ronkainen
BACKGROUND CONTEXT: Laryngeal penetration-aspiration, entry of material into the airways, is considered the most severe subtype of dysphagia and common among patients with acute cervical spinal cord injury. PURPOSE: The aim of this study was to investigate risk factors for penetration-aspiration in patients with acute traumatic cervical spinal cord injury (TCSCI). STUDY DESIGN: A prospective cohort study. PATIENT SAMPLE: Thirty-seven patients with TCSCI...
June 30, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28673827/the-impact-of-spine-stability-on-cervical-spinal-cord-injury-with-respect-to-demographics-management-and-outcome-a-prospective-cohort-from-a-national-sci-registry
#16
Jérôme Paquet, Carly S Rivers, Dilinuer Kuerban, Joel Finkelstein, Jin W Tee, Vanessa K Noonan, Brian K Kwon, R John Hurlbert, Sean Christie, Eve C Tsai, Henry Ahn, Brian Drew, Christopher S Bailey, Daryl R Fourney, Najmedden Attabib, Michael G Johnson, Michael G Fehlings, Stefan Parent, Marcel F Dvorak
BACKGROUND CONTEXT: Emergent surgery for patients with a traumatic spinal cord injury (SCI) is seen as the gold standard in acute management. However, optimal treatment for those with the clinical diagnosis of central cord syndrome (CCS) is less clear and classic definitions of CCS do not identify a unique population of patients. PURPOSE: To test the authors' hypothesis that spine stability can identify a unique group of patients with regards to demographics, management, and outcomes, which classic CCS definitions do not...
June 30, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28673824/incorporating-ligament-laxity-in-a-finite-element-model-for-the-upper-cervical-spine
#17
Timothy L Lasswell, Duane S Cronin, John B Medley, Parham Rasoulinejad
BACKGROUND CONTEXT: Predicting physiological range of motion (ROM) using a finite element (FE) model of the upper cervical spine requires the incorporation of ligament laxity. The effect of ligament laxity can only be observed on a macro level of joint motion and is lost once ligaments have been dissected and preconditioned for experimental testing. As a result, although ligament laxity values are recognized to exist, specific values are not directly available in the literature for use in FE models...
June 30, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28672365/conflicts-of-interest-reported-in-an-abbreviated-time-frame-reply
#18
Akilah A Jefferson, Steven D Pearson
No abstract text is available yet for this article.
July 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28672362/conflicts-of-interest-reported-in-an-abbreviated-time-frame
#19
Anna S Lok, William G Powderly
No abstract text is available yet for this article.
July 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28670401/the-clinical-correlations-between-diabetes-cigarette-smoking-and-obesity-on-intervertebral-degenerative-disc-disease-of-the-lumbar-spine
#20
Ande M Jakoi, Gurpal Pannu, Anthony D'Oro, Zorica Buser, Martin H Pham, Neil N Patel, Patrick C Hsieh, John C Liu, Frank L Acosta, Raymond Hah, Jeffrey C Wang
STUDY DESIGN: Retrospective analysis of a nationwide private insurance database. Chi-square analysis and linear regression models were utilized for outcome measures. PURPOSE: The purpose of this study was to investigate any relationship between lumbar degenerative disc disease, diabetes, obesity and smoking tobacco. OVERVIEW OF LITERATURE: Diabetes, obesity, and smoking tobacco are comorbid conditions known to individually have effect on degenerative disc disease...
June 2017: Asian Spine Journal
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