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"Conflict of interest"

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https://www.readbyqxmd.com/read/28818564/validity-of-a-smartphone-protractor-to-measure-sagittal-parameters-in-adult-spinal-deformity
#1
William Aaron Kunkle, Michael Madden, Shannon Potts, Jeremy Fogelson, Stuart Hershman
BACKGROUND CONTEXT: Smartphones have become an integral tool in the daily life of healthcare professionals (Franko 2011). Their ease of use and wide availability often make smartphones the first tool surgeons use to perform measurements. This technique has been validated for certain orthopaedic pathologies (Shaw 2012, Quek 2014, Milanese 2014, Milani 2014), but never to assess sagittal parameters in adult spinal deformity. This study was designed to assess the validity, reproducibility, precision and efficiency of using a smartphone protractor application to measure sagittal parameters commonly measured in adult spinal deformity assessment and surgical planning...
August 14, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28810691/improvement-of-implantation-potential-in-mouse-blastocysts-derived-from-ivf-by-combined-treatment-with-prolactin-epidermal-growth-factor-and-4-hydroxyestradiol
#2
Miki Takeuchi, Misato Seki, Etsuko Furukawa, Akihito Takahashi, Kyosuke Saito, Mitsuru Kobayashi, Kenji Ezoe, Emiko Fukui, Midori Yoshizawa, Hiromichi Matsumoto
STUDY QUESTION: Can supplementation of medium with prolactin (PRL), epidermal growth factor (EGF) and 4-hydroxyestradiol (4-OH-E2) prior to embryo transfer improve implantation potential in mouse blastocysts derived from IVF? SUMMARY ANSWER: Combined treatment with PRL, EGF and 4-OH-E2 improves mouse blastocyst implantation rates, while alone, each factor is ineffective. WHAT IS KNOWN ALREADY: Blastocyst dormancy during delayed implantation caused by ovariectomy is maintained by continued progesterone treatment in mice, and estrogen injection rapidly activates blastocysts to implantation-induced status in vivo...
August 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28797266/does-growing-up-with-a-physician-influence-the-ethics-of-medical-students-relationships-with-the-pharmaceutical-industry-the-cases-of-the-us-and-poland
#3
Marta Makowska
BACKGROUND: Medical schools have a major impact on future doctors' ethics and their attitudes towards cooperation with the pharmaceutical industry. From childhood, medical students who are related to a physician are exposed to the characteristics of a medical career and learn its professional ethics not only in school but also in the family setting. The present paper sought to answer the research question: 'How does growing up with a physician influence medical students' perceptions of conflicts of interest in their relationships with industry?' METHODS: An anonymous questionnaire was completed by 451 medical students from four Philadelphia medical schools and 554 medical students from Warsaw Medical University during 2013...
August 10, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28780525/medical-students-perceptions-of-professional-misconduct-relationship-with-typology-and-year-of-programme
#4
Juliana Zulkifli, Brad Noel, Deirdre Bennett, Siun O'Flynn, Colm O'Tuathaigh
AIM: To examine the contribution of programme year and demographic factors to medical students' perceptions of evidence-based classification categories of professional misconduct. METHODS: Students at an Irish medical school were administered a cross-sectional survey comprising 31 vignettes of professional misconduct, which mapped onto a 12-category classification system. Students scored each item using a 5-point Likert scale, where 1 represents the least severe form of misconduct and 5 the most severe...
August 5, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28771633/methodological-quality-of-systematic-reviews-referenced-in-clinical-practice-guidelines-for-the-treatment-of-opioid-use-disorder
#5
Andrew Ross, Justin Rankin, Jason Beaman, Kelly Murray, Philip Sinnett, Ross Riddle, Jordan Haskins, Matt Vassar
INTRODUCTION: With efforts to combat opioid use disorder, there is an increased interest in clinical practice guidelines (CPGs) for opioid use disorder treatments. No literature exists examining the quality of systematic reviews used in opioid use disorder CPGs. This study aims to describe the methodological quality and reporting clarity of systematic reviews (SRs) used to create CPGs for opioid use disorder. METHODS: From June to July 2016 guideline clearinghouses and medical literature databases were searched for relevant CPGs used in the treatment of opioid use disorder...
2017: PloS One
https://www.readbyqxmd.com/read/28758242/should-disclosure-of-conflicts-of-interest-in-medicine-be-made-public-medical-students-views
#6
Jane Williams, Wendy Lipworth, Christopher Mayes, Ian Olver, Ian Kerridge
CONTEXT: Conflicts of interest (CoIs) are considered to be ubiquitous in health care and biomedicine. The disclosure of relevant interests is a first step in managing conflicts, although its usefulness is contested. Although several countries have mandated the public disclosure of doctors' financial relationships with the pharmaceutical industry, little is known about medical students' understanding of mandatory public disclosure. METHODS: Six 90-minute focus groups were conducted with medical students in New South Wales, Australia...
July 31, 2017: Medical Education
https://www.readbyqxmd.com/read/28756302/both-positive-and-negative-beliefs-are-important-in-patients-with-spine-pain-findings-from-the-oioc-registry
#7
Maria M Wertli, Ulrike Held, Angela Lis, Marco Campello, Sherri Weiser
BACKGROUND CONTEXT: Negative beliefs are known to influence treatment outcome in patients with spine pain (SP). The impact of positive beliefs is less clear. PURPOSE: Assess the influence of positive and negative beliefs on baseline and treatment responses in patients with SP. STUDY DESIGN/SETTING: Retrospective cross-sectional and longitudinal analysis of prospectively collected data of outpatient physical therapy patients with SP. Questionnaires administered before and during treatment included the STarT Back distress scale (negative beliefs), and expectation and self-efficacy questions (positive beliefs)...
July 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28752507/intravenous-alteplase-for-acute-ischemic-stroke-in-taiwan-can-we-expand-the-national-health-insurance-s-reimbursement-criteria
#8
Cheng-Yang Hsieh
lization of intravenous thrombolysis with alteplase was very low in Taiwanese patients with acute ischemic stroke(1). One of the reasons is the strict reimbursement guideline made by the Bureau of National Health Insurance (NHI) in 2004(2). In this issue of the Acta Neurologica Taiwanica, Yu-Hsiang Su and co-authors(3) retrospectively evaluated outcomes of their thrombolysed stroke patients who were "mismatched" between updated clinical practice guideline and NHI reimbursement criteria. They concluded that the outcomes of patients treated according to guidelines were comparable between the reimbursement and non-reimbursement groups...
March 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/28751241/flexibility-assessment-of-the-unfused-thoracic-segments-above-the-potential-upper-instrumented-vertebra-using-the-supine-side-bending-radiographs-in-lenke-5-and-6-curves-for-adolescent-idiopathic-scoliosis-patients
#9
Mun Keong Kwan, Chee Kidd Chiu, Teik Seng Chan, Siti Mariam Abd Gani, Tan Shurn Heng, Chris Yin Wei Chan
BACKGROUND CONTEXT: Selection of UIV for Lenke 5 and 6 curves remains debatable, and several authors had described different selection strategies. OBJECTIVE: This study analyzed the flexibility of the unfused thoracic segments above the 'potential upper instrumented vertebrae (UIV)' (T1 to T12) and its compensatory ability in Lenke 5 and 6 curves using supine side bending (SSB) radiographs. STUDY DESIGN: Retrospective study PATIENT SAMPLE: 100 patients OUTCOME MEASURES: The ability of the unfused thoracic segments above the 'potential upper instrumented vertebrae (UIV)' i...
July 24, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28749536/the-lack-of-a-relationship-between-physician-payments-from-drug-manufacturers-and-medicare-claims-for-abiraterone-and-enzalutamide
#10
Jathin Bandari, Omar M Ayyash, Robert M Turner, Bruce L Jacobs, Benjamin J Davies
BACKGROUND: Interactions between industry and prescribers have raised concerns regarding conflicts of interest. To the best of the authors' knowledge, quantitative data measuring these interactions have been limited until recently. In the current study, the authors sought to determine whether an association exists between industry payments and prescriber behavior with regard to abiraterone and enzalutamide. METHODS: Two Centers for Medicare and Medicaid Services databases were combined to analyze oncologists and urologists who received industry payments and/or prescribed abiraterone and enzalutamide...
July 27, 2017: Cancer
https://www.readbyqxmd.com/read/28748064/publication-practices-and-responsible-authorship-a-review-article
#11
REVIEW
Elvis E Tarkang, Margaret Kweku, Francis B Zotor
Dissemination of research findings through the publication of one's work or a group of contributors is an important part of the research process, as this allows the passing on of benefits to a much wider community. In whatever evocative form this dissemination may take, the onus lies on the author(s) to ensure adherence to the code of ethics as it pertains to the integrity of the information being put out. We publish because we want our findings to be adapted into practice and application, or in some cases may be relevant to policy makers in decision-making...
June 23, 2017: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/28747226/self-declared-stock-ownership-and-association-with-positive-trial-outcome-in-randomized-controlled-trials-with-binary-outcomes-published-in-general-medical-journals-a-cross-sectional-study
#12
Alberto Falk Delgado, Anna Falk Delgado
BACKGROUND: Describe the prevalence and types of conflicts of interest (COI) in published randomized controlled trials (RCTs) in general medical journals with a binary primary outcome and assess the association between conflicts of interest and favorable outcome. METHODS: Parallel-group RCTs with a binary primary outcome published in three general medical journals during 2013-2015 were identified. COI type, funding source, and outcome were extracted. Binomial logistic regression model was performed to assess association between COI and funding source with outcome...
July 26, 2017: Trials
https://www.readbyqxmd.com/read/28746698/missing-conflict-of-interest-disclosure
#13
(no author information available yet)
No abstract text is available yet for this article.
August 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28745950/declaring-conflict-of-interest-current-state-of-affairs-in-the-ophthalmic-literature
#14
Jamie Lea Schaefer, Noemie Aubert Bonn, Geert Craenen
CONTEXT: The importance of transparency with financial ties in biomedical research is widely recognized, and most peer-reviewed journals require declarations of Conflicts of Interest (COI). Nonetheless, variability in the consistency of declarations of COI has been sparsely assessed. OBJECTIVES: To assess consistency and rates of COI declarations in the ophthalmic literature and the effectiveness of journal COI policies. METHODS: We analyzed consistency and completeness of declaration of COI in the ophthalmic literature and compared the levels of completeness to specific journal requirements...
July 26, 2017: Accountability in Research
https://www.readbyqxmd.com/read/28741747/defending-the-scientific-integrity-of-conservation-policy-processes
#15
Carlos Carroll, Brett Hartl, Gretchen T Goldman, Daniel J Rohlf, Adrian Treves, Jeremy T Kerr, Euan G Ritchie, Richard T Kingsford, Katherine E Gibbs, Martine Maron, James E M Watson
Government agencies faced with politically controversial decisions often discount or ignore scientific information, whether from agency staff or nongovernmental scientists. Recent developments in scientific integrity (the ability to perform, use, communicate, and publish science free from censorship or political interference) in Canada, Australia, and the United States demonstrate a similar trajectory. A perceived increase in scientific-integrity abuses provokes concerted pressure by the scientific community, leading to efforts to improve scientific-integrity protections under a new administration...
July 25, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28740618/ethical-issues-associated-with-medical-tourism-in-africa
#16
REVIEW
John J O Mogaka, Lucia Mupara, Joyce M Tsoka-Gwegweni
Global disparities in medical technologies, laws, economic inequities, and social-cultural differences drive medical tourism (MT), the practice of travelling to consume healthcare that is either too delayed, unavailable, unaffordable or legally proscribed at home. Africa is simultaneously a source and destination for MT. MT however, presents a new and challenging health ethics frontier, being largely unregulated and characterized by policy contradictions, minority discrimination and conflict of interest among role-players...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28739479/emergency-department-visits-after-lumbar-spine-surgery-are-associated-with-lower-hcahps-scores
#17
Jay M Levin, Robert D Winkelman, Gabriel A Smith, Joseph E Tanenbaum, Roy Xiao, Thomas E Mroz, Michael P Steinmetz
BACKGROUND: Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) surveys are used to assess the quality of the patient experience following an inpatient stay. HCAHPS scores are used to determine reimbursement for hospital systems and incentivize spine surgeons nationwide. There are conflicting data detailing whether early readmission or other post-discharge complications are associated with patient responses on the HCAHPS survey. Currently, the association between post-discharge ED visits and HCAHPS scores following lumbar spine surgery is unknown...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28739232/conflict-of-interest
#18
John R Clark
No abstract text is available yet for this article.
July 2017: Air Medical Journal
https://www.readbyqxmd.com/read/28737987/factors-associated-with-patient-preferences-for-disease-modifying-therapies-in-multiple-sclerosis
#19
Ana L Hincapie, Jonathan Penm, Craig F Burns
BACKGROUND: Treatment adherence in patients with multiple sclerosis (MS) is essential to reduce the rate of acute neurological attacks, severity of relapses, and hospitalizations and to slow its progression. Adherence rates in MS patients have been shown to be affected by multiple factors, including physical or cognitive difficulties, perceived lack of treatment efficacy, treatment-related adverse events, injection anxiety, and frequency of administration. OBJECTIVE: To elicit the preferences of MS patients for noneconomic and economic attributes of current disease-modifying therapies (DMTs)...
August 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28737984/evaluating-the-training-responsibilities-and-practices-of-p-t-committee-members-and-nonmember-contributors
#20
Ryan Rodriguez, Brett J Kelly, Mary Moody
BACKGROUND: Pharmacy and therapeutics (P&T) committees are responsible for managing drug formularies in numerous health care settings. Although pharmacy practice and health care organizations provide general recommendations of responsibilities and skills for members and nonmember contributors of P&T committees, the study investigators hypothesized that there is diversity in the training, responsibilities, and practices of these members and contributors. OBJECTIVE: To describe the training, responsibilities, and practices of members and nonmember contributors of P&T committees in a variety of health care settings, using an online survey...
August 2017: Journal of Managed Care & Specialty Pharmacy
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