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https://www.readbyqxmd.com/read/28419083/pneumococcal-vaccination-and-efficacy-in-patients-with-heterotaxy-syndrome
#1
Pei-Lan Shao, Mei-Hwan Wu, Jou-Kou Wang, Hui-Wen Hsu, Li-Min Huang, Shuenn-Nan Chiu
BACKGROUND: Pneumococcal vaccines, including pneumococcal polysaccharide vaccine (PPV) and pneumococcal conjugated vaccine (PCV), are important in preventing invasive pneumococcal disease. We analyzed the pneumococcal vaccination rate, efficacy and durability in patients with heterotaxy. METHODS: All patients with heterotaxy and CCHD who were followed at our institution between 2010 and 2015 were included. Pneumococcal vaccine status and geometric mean concentration (GMC) of serotypes 6B, 14, 19F, and 23F were analyzed...
April 18, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28400075/review-of-general-dental-council-and-general-medical-council-fitness-to-practise-hearings-related-to-maxillofacial-surgery
#2
R Taylor, M H Ali, T E Howe, I Varley
Dually-registered specialists in oral and maxillofacial surgery (OMFS) may be subject to disciplinary hearings by the General Medical Council (GMC) and the General Dental Council (GDC) for the same allegations, a phenomenon referred to as "double jeopardy" within the specialty. Previous efforts by both councils to simplify regulatory arrangements have made little progress. We have therefore reviewed the range and scope of fitness to practise (FTP) proceedings relevant to OMFS. We searched the online GMC register to find registered OMFS specialists and obtained FTP proceedings from 2004-2016 through a Freedom of Information request from the GDC...
April 8, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28399054/pneumococcal-immune-response-in-infants-whose-mothers-received-tdap-vaccination-during-pregnancy
#3
Kirsten Maertens, Polly Burbidge, Pierre Van Damme, David Goldblatt, Elke Leuridan
BACKGROUND: Maternal immunization with a tetanus, diphtheria and acellular pertussis (Tdap) vaccine may blunt infant pneumococcal immune responses after a primary series of vaccines. METHODS: As part of a prospective controlled cohort trial of Tdap (Boostrix®, GSK Biologicals) vaccination in pregnancy, infants born to vaccinated mothers and controls were immunized at 8 and 16 weeks and 12 months of age with 13-valent pneumococcal conjugate vaccine (Prevenar13®, Pfizer)...
April 10, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28395468/-antibody-persistence-following-on-different-vaccination-strategies-of-domestic-measles-mumps-and-rubella-combined-attenuated-live-vaccine-a-3-year-follow-up-study
#4
H Q He, Q Li, R Yan, Y Zhou, X W Tang, X Deng, S Y Xie, Z P Chen
Objective: To assess the 3-year antibody persistence after vaccination of domestic measles, mumps and rubella combined attenuated live vaccine (MMR) with different program. Methods: Children from three different vaccination strategies (Group 8 m MR: 8 months and 18 months vaccinated with measles-rubella combined attenuated live vaccine and domestic MMR,respectively; Group 8 m MMR: 8 months and 18 months both vaccinated with domestic MMR; Group 12 m MMR: 12 months and 22 months both vaccinated with domestic MMR ) were followed up in Zhejiang province in July 2015...
April 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28378445/rice-no-pollen-1-np1-is-required-for-anther-cuticle-formation-and-pollen-exine-patterning
#5
Ze Liu, Sen Lin, Jianxin Shi, Jing Yu, Lu Zhu, Xiujuan Yang, Dabing Zhang, Wanqi Liang
Angiosperm male reproductive organs (anthers and pollen grains) have complex and interesting morphological features, but mechanisms that underlie their patterning are poorly understood. Here we report the isolation and characterization of a male sterile mutant of No Pollen 1 (NP1) in rice (Oryza sativa). The np1-4 mutant exhibited smaller anthers with a smooth cuticle surface, abnormal Ubisch bodies, and aborted pollen grains covered with irregular exine. Wild-type exine has two continuous layers; but np1-4 exine showed a discontinuous structure with large granules of varying size...
April 4, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28373174/switching-specialties-must-be-made-easier-says-gmc
#6
Abi Rimmer
No abstract text is available yet for this article.
April 3, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28372544/prevalence-of-gmc-performance-assessments-in-the-united-kingdom-a-retrospective-cohort-analysis-by-country-of-medical-qualification
#7
L Mehdizadeh, H W W Potts, A Sturrock, J Dacre
BACKGROUND: The demographics of doctors working in the UK are changing. The United Kingdom (UK) has voted to leave the European Union (EU) and there is heightened political discourse around the world about the impact of migration on healthcare services. Previous work suggests that foreign trained doctors perform worse than UK graduates in postgraduate medical examinations. We analysed the prevalence by country of primary medical qualification of doctors who were required to take an assessment by the General Medical Council (GMC) because of performance concerns...
April 4, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28353567/are-normal-hips-being-labeled-as-femoroacetabular-impingement-due-to-ee-angle
#8
Tian You, Bei Yang, Xin-Tao Zhang, Xiao-Cheng Jiang, Shuang Wang, Wen-Tao Zhang
Gluteal muscle contracture (GMC) is a clinical syndrome characterized by gait abnormality and limb dysfunction, as well as secondary deformities of pelvis and femur. Femoroacetabular impingement (FAI) typically could be diagnosed on the basis of computed tomography (CT) such as the equatorial-edge angle (EE angle), but it did not work well in GMC patients. In this study, we retrospected all image data and found small EE angles in GMCs, which meant retroverted acetabulum; however, none of them showed no symptoms and signs of FAI...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28343774/immunogenicity-and-safety-of-a-high-dose-hepatitis-b-vaccine-among-patients-receiving-methadone-maintenance-treatment-a-randomized-double-blinded-parallel-controlled-trial
#9
Jing Shi, Yongliang Feng, Linying Gao, Dan Feng, Tian Yao, Shan Shi, Yawei Zhang, Xiaofeng Liang, Suping Wang
BACKGROUND AND AIMS: To explore whether the immunization with high-dose (60μg) hepatitis B vaccines in patients receiving methadone maintenance treatment (MMT) could yield a superior protection against hepatitis B infection than did the standard dose (20μg). METHODS: We conducted a randomized, double-blinded, parallel-controlled trial in MMT patients. Patients with serologically negative hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) were randomized in a ratio of 1:1 to receive three intramuscular injections of 20μg or 60μg recombinant hepatitis B vaccine at months 0, 1, and 6...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28325554/inscuteable-maintains-type-i-neuroblast-lineage-identity-via-numb-notch-signaling-in-the-drosophila-larval-brain
#10
Huanping An, Wanzhong Ge, Yongmei Xi, Xiaohang Yang
In the Drosophila larval brain, type I and type II neuroblasts (NBs) undergo a series of asymmetric divisions which give rise to distinct progeny lineages. The intermediate neural progenitors (INPs) exist only in type II NB lineages. In this study, we reveal a novel function of Inscuteable (Insc) that acts to maintain type I NB lineage identity. In insc type I NB clones of mosaic analyses with a repressible cell marker (MARCM), the formation of extra Deadpan (Dpn)(+) NB-like and GMC-like cells is observed. The lack of Insc leads to the defective localization and segregation of Numb during asymmetric cell division...
March 6, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28316280/predicting-fitness-to-practise-events-in-international-medical-graduates-who-registered-as-uk-doctors-via-the-professional-and-linguistic-assessments-board-plab-system-a-national-cohort-study
#11
Paul A Tiffin, Lewis W Paton, Lazaro M Mwandigha, John C McLachlan, Jan Illing
BACKGROUND: International medical graduates working in the UK are more likely to be censured in relation to fitness to practise compared to home graduates. Performance on the General Medical Council's (GMC's) Professional and Linguistic Assessments Board (PLAB) tests and English fluency have previously been shown to predict later educational performance in this group of doctors. It is unknown whether the PLAB system is also a valid predictor of unprofessional behaviour and malpractice...
March 20, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28302115/arthroscopic-release-using-f-and-c-method-versus-conventional-open-release-method-in-the-treatment-of-gluteal-muscle-contracture-a-comparative-study
#12
Saroj Rai, Shengyang Jin, Chunqing Meng, Nabin Chaudhary, Nira Tamang, Xiaohong Wang, Xianzhe Liu, Hong Wang, Shuhua Yang
BACKGROUND: Gluteal muscle contracture (GMC), a debilitating disease, usually starts in early childhood after variable dose of injections around the buttock, if left untreated it worsens gradually and persists throughout the life. Because the disease mostly affects adolescents and adults, there is always an aesthetic concerns. Purposeof the study was to introduce the arthroscopic F and C method of GMC release, and to compare its clinical efficiency with conventional open surgery in terms of clinical outcome, rate of complications, patient's satisfactions, and recurrence...
March 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28298265/supervised-machine-learning-algorithms-can-classify-open-text-feedback-of-doctor-performance-with-human-level-accuracy
#13
Chris Gibbons, Suzanne Richards, Jose Maria Valderas, John Campbell
BACKGROUND: Machine learning techniques may be an effective and efficient way to classify open-text reports on doctor's activity for the purposes of quality assurance, safety, and continuing professional development. OBJECTIVE: The objective of the study was to evaluate the accuracy of machine learning algorithms trained to classify open-text reports of doctor performance and to assess the potential for classifications to identify significant differences in doctors' professional performance in the United Kingdom...
March 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28292853/trusts-must-encourage-junior-doctors-to-report-long-working-hours-gmc-says
#14
Abi Rimmer
No abstract text is available yet for this article.
March 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28291024/pavlik-harness-treatment-for-pathological-developmental-dysplasia-of-the-hip-meeting-the-standard
#15
Qaisar Choudry, Robin W Paton
In the UK, the Pavlik harness is generally the accepted treatment technique for the treatment of neonatal and infant pathological developmental dysplasia of the hip. In 2013, the success rate of the Pavlik harness became an outcome measure from the British Society of Children's Orthopaedic Surgery for appraisal and revalidation with the GMC for paediatric orthopaedic surgery. The standard set requires an 80% success rate, with less than 20% requiring surgery. This study evaluated the outcomes of Pavlik harness treatment in neonates/infants with 'pathological hips' diagnosed by ultrasound imaging in a district general hospital setting...
March 13, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28282742/tracking-of-gross-motor-coordination-in-portuguese-children
#16
Rafael S Henrique, Alcibíades V Bustamante, Duarte L Freitas, Go Tani, Peter T Katzmarzyk, José A Maia
The purpose of this study was to investigate the tracking of gross motor coordination (GMC) and to profile children at 6 years of age who consistently showed higher stability patterns in different levels of GMC. The participants were 245 children (123 boys and 122 girls) who were assessed longitudinally from 6 to 9 years of age. GMC was assessed using the Korperkoordinationtest fur Kinder (KTK) test battery. Anthropometry, physical activity, and health- and performance-related physical fitness were also measured...
March 1, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28280059/a-medical-curriculum-in-transition-audit-and-student-perspective-of-undergraduate-teaching-of-ethics-and-professionalism
#17
Toni C Saad, Stephen Riley, Richard Hain
INTRODUCTION: The General Medical Council (GMC) stipulates that doctors must be competent professionals, not merely scholars and practitioners. Medical school curricula should enable students to develop professional values and competencies. Additionally, medical schools are moving towards integrated undergraduate curricula, Cardiff's C21 being one such example. METHODS: We carried out an audit to determine the extent to which C21 delivers GMC professionalism competencies, and a student questionnaire to explore student perspective on ethics and professionalism...
March 9, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28277132/maternal-serum-cytokine-levels-in-pregnancies-complicated-with-threatened-preterm-labour
#18
Alejandra Herrera-Muñoz, Ana M Fernández-Alonso, Natalia Fischer-Suárez, Peter Chedraui, Faustino R Pérez-López
OBJECTIVE: To investigate serum inflammatory markers in singleton gestations complicated with threatened preterm labour (TPL). METHODS: Pregnant women complicated with TPL (n = 61) were recruited to measure maternal serum levels of a panel of cytokines and C-reactive protein and then compared to controls without TPL, matched for gestational age (n = 64) and term pregnancies in the prodromal phase of labour (PPL) (n = 31). In addition, baseline cytokine levels were compared among cases and controls according to the outcome...
February 21, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28272974/persistence-of-immunity-18-19%C3%A2-years-after-vaccination-against-hepatitis-b-in-2-cohorts-of-vaccinees-primed-as-infants-or-as-adolescents-in-italy
#19
Luisa Romanò, Cristina Galli, Catia Tagliacarne, Maria Elena Tosti, Claudio Velati, Laura Fomiatti, Maria Chironna, Rosa Cristina Coppola, Mario Cuccia, Rossana Mangione, Fosca Marrone, Francesco Saverio Negrone, Antonino Parlato, Carla Maria Zotti, Alfonso Mele, Alessandro Remo Zanetti
This study was aimed at assessing the anti-HBs persistence and immune memory 18-19 y after vaccination against hepatitis B in healthy individuals primed as infants or adolescents. We enrolled 405 teenagers (Group A) vaccinated as infants, and 409 young adults (Group B) vaccinated as adolescents. All vaccinees were tested for anti-HBs and anti-HBc antibodies; those found anti-HBc positive were further tested for HBsAg and HBV DNA. Eight individuals belonging to Group B were positive for anti-HBc alone, and were excluded from analysis...
March 8, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28254995/half-of-nhs-doctors-trained-in-other-eu-countries-are-considering-quitting-uk-warns-gmc
#20
Adrian O'Dowd
No abstract text is available yet for this article.
March 2, 2017: BMJ: British Medical Journal
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