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https://www.readbyqxmd.com/read/29666109/gmc-should-lose-right-to-appeal-fitness-to-practise-decisions-says-bma
#1
Abi Rimmer
No abstract text is available yet for this article.
April 17, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29628171/-run-through-training-at-specialist-training-year-1-and-uncoupled-core-surgical-training-for-oral-and-maxillofacial-surgery-in-the-united-kingdom-a-snapshot-survey
#2
M Garg, J Collyer, D Dhariwal
Training in oral and maxillofacial surgery (OMFS) in the UK has undergone considerable changes during the last 10years, and "core" surgical training has replaced "basic" surgical training. In 2014 a pilot "run-through" training programme from specialist training year one (ST1)-ST7 was introduced to facilitate early entry into the speciality. Run-through training guarantees that a trainee, after a single competitive selection process and satisfactory progress, will be given training that covers the entire curriculum of the speciality, whereas uncoupled training requires a second stage of competitive recruitment after the first one (for OMFS only) or two years of "core" training to progress to higher specialty training...
April 5, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29627147/determinants-of-antibody-persistence-across-doses-and-continents-after-single-dose-rvsv-zebov-vaccination-for-ebola-virus-disease-an-observational-cohort-study
#3
Angela Huttner, Selidji Todagbe Agnandji, Christophe Combescure, José F Fernandes, Emmanuel Bache Bache, Lumeka Kabwende, Francis Maina Ndungu, Jessica Brosnahan, Thomas P Monath, Barbara Lemaître, Stéphane Grillet, Miriam Botto, Olivier Engler, Jasmine Portmann, Denise Siegrist, Philip Bejon, Peter Silvera, Peter Kremsner, Claire-Anne Siegrist
BACKGROUND: The recombinant vesicular stomatitis virus (rVSV) vaccine expressing the Zaire Ebola virus (ZEBOV) glycoprotein is efficacious in the weeks following single-dose injection, but duration of immunity is unknown. We aimed to assess antibody persistence at 1 and 2 years in volunteers who received single-dose rVSV-ZEBOV in three previous trials. METHODS: In this observational cohort study, we prospectively followed-up participants from the African and European phase 1 rVSV-ZEBOV trials, who were vaccinated once in 2014-15 with 300 000 (low dose) or 10-50 million (high dose) plaque-forming units (pfu) of rVSV-ZEBOV vaccine to assess ZEBOV glycoprotein (IgG) antibody persistence...
April 4, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29625566/passing-mrcp-uk-paces-a-cross-sectional-study-examining-the-performance-of-doctors-by-sex-and-country
#4
Emily Unwin, Henry W W Potts, Jane Dacre, Andrew Elder, Katherine Woolf
BACKGROUND: There is much discussion about the sex differences that exist in medical education. Research from the United Kingdom (UK) and United States has found female doctors earn less, and are less likely to be senior authors on academic papers, but female doctors are also less likely to be sanctioned, and have been found to perform better academically and clinically. It is also known that international medical graduates tend to perform more poorly academically compared to home-trained graduates in the UK, US, and Canada...
April 6, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29602785/the-pyrroloquinoline-quinone-dependent-pyranose-dehydrogenase-from-coprinopsis-cinerea-cc-pdh-drives-lytic-polysaccharide-monooxygenase-lpmo-action
#5
Anikó Várnai, Kiwamu Umezawa, Makoto Yoshida, Vincent G H Eijsink
Fungi secrete a set of glycoside hydrolases and oxidoreductases, including lytic polysaccharide monooxygenases (LPMOs), for the degradation of plant polysaccharides. LPMOs catalyze the oxidative cleavage of glycosidic bonds after activation by an external electron donor. So far, only flavin-dependent oxidoreductases (from the auxiliary activity family AA3) have been shown to activate LPMOs. Here we present LPMO activation by a pyrroloquinoline-quinone (PQQ)-dependent pyranose dehydrogenase (PDH) from Coprinopsis cinerea , Cc PDH, the founding member of the recently discovered auxiliary activity family AA12...
March 30, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29588322/gmc-calls-for-law-change-to-make-doctors-reflections-legally-protected
#6
Clare Dyer
No abstract text is available yet for this article.
March 27, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29563105/doctor-is-struck-off-for-sexual-assaults-on-two-women-after-gmc-wins-appeal
#7
Clare Dyer
No abstract text is available yet for this article.
March 21, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29555643/gmc-is-given-time-to-respond-to-allegations-it-failed-doctor-who-stole-fentanyl
#8
Clare Dyer
No abstract text is available yet for this article.
March 19, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29546255/undiluted-human-whole-blood-uric-acid-detection-using-a-graphitized-mesoporous-carbon-modified-electrode-a-potential-tool-for-clinical-point-of-care-uric-acid-diagnosis
#9
Khairunnisa Amreen, Sivakumar Nisha, Annamalai Senthil Kumar
Direct sensing of uric acid (UA) in an undiluted whole blood sample is reported here taking human whole blood as an analyte and a self-supporting electrolyte. Among various solid electrodes (Pt, Au, GCE, and GCE/Nafion) and carbon nanomaterials (carbon nanofibers, graphene oxide, graphite nanopowder, graphitized mesoporous carbon (GMC), single-walled carbon nanotubes, and multiwalled carbon nanotubes) tested, a GMC-modified glassy carbon electrode, designated as GCE/GMC, showed a remarkable response towards direct electrochemical oxidation of blood uric acid at ∼0...
March 16, 2018: Analyst
https://www.readbyqxmd.com/read/29531140/gp-leaders-pass-vote-of-no-confidence-in-gmc
#10
Gareth Iacobucci
No abstract text is available yet for this article.
March 12, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29497369/reduced-orbitofrontal-gray-matter-concentration-as-a-marker-of-premorbid-childhood-trauma-in-cocaine-use-disorder
#11
Keren Bachi, Muhammad A Parvaz, Scott J Moeller, Gabriela Gan, Anna Zilverstand, Rita Z Goldstein, Nelly Alia-Klein
Background : Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and cognitive control may be an underlying substrate, as documented separately in addiction and for childhood trauma. The purpose of this study was to understand the contribution of childhood maltreatment to GMC effects in individuals with cocaine use disorder. Methods : Individuals with cocaine use disorder were partitioned into groups of low vs...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29486629/higher-specialty-training-in-genitourinary-medicine-a-curriculum-competencies-based-approach
#12
Mitesh Desai, Olubanke Davies, Anatole Menon-Johansson, Gulshan Cindy Sethi
Specialty trainees in genitourinary medicine (GUM) are required to attain competencies described in the GUM higher specialty training curriculum by the end of their training, but learning opportunities available may conflict with service delivery needs. In response to poor feedback on trainee satisfaction surveys, a four-year modular training programme was developed to achieve a curriculum competencies-based approach to training. We evaluated the clinical opportunities of the new programme to determine: (1) Whether opportunity cost of training to service delivery is justifiable; (2) Which competencies are inadequately addressed by direct clinical opportunities alone and (3) Trainee satisfaction...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29483074/trainee-gp-who-falsified-timesheet-is-suspended-for-four-months-after-gmc-intervened
#13
Clare Dyer
No abstract text is available yet for this article.
February 26, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29478347/waning-immunity-of-one-dose-measles-mumps-rubella-vaccine-to-mumps-in-children-from-kindergarten-to-early-school-age-a-prospective-study
#14
Yuanbao Liu, Zhihao Liu, Xiuying Deng, Ying Hu, Zhiguo Wang, Peishan Lu, Hongxiong Guo, Xiang Sun, Yan Xu, Fenyang Tang, Feng-Cai Zhu
BACKGROUND: In China, only one dose measles-mumps-rubella vaccine (MMR) was administered to children aged 18-24 months. However, the mumps incidence was still high, and the epidemiological incidence shifted to the older age groups. Data on the waning immunity to mumps after MMR vaccination are limited. This study aimed to describe the waning immunity to mumps in kindergarten and primary school children to provide a scientific basis for confirming an optimal age for a second dose. METHODS: An observational, prospective study on one-dose MMR in children in kindergarten and primary school was conducted from 2015 to 2016...
February 26, 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/29475243/the-impact-of-general-medical-conditions-in-obsessive-compulsive-disorder
#15
Andrea Aguglia, Maria Salvina Signorelli, Umberto Albert, Giuseppe Maina
Objective: The co-occurrence of general medical conditions (GMCs) and major psychiatric disorders is well documented. The aim of this study was to assess the prevalence of GMCs in patients with a primary diagnosis of obsessive-compulsive disorder (OCD) and, secondly, to investigate which clinical variables are associated with the presence of a GMC. Methods: Subjects with a primary diagnosis of OCD were included. Socio-demographic and clinical characteristics were collected...
February 22, 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/29458006/mechanistic-studies-of-formate-oxidase-from-aspergillus-oryzae-a-novel-member-of-the-glucose-methanol-choline-oxidoreductase-enzyme-superfamily-that-oxidizes-carbon-acids
#16
John M Robbins, Andreas S Bommarius, Giovanni Gadda
Formate oxidase (FOX) from Aspergillus oryzae is the only GMC member that oxidizes a carbon acid rather than alcohols; thus, its catalytic mechanism may be different from that of other GMC members. We have used pH, solvent viscosity, and deuterium kinetic isotope effects, to investigate the catalytic mechanism of FOX. The enzyme followed a Bi-Bi sequential steady-state kinetic mechanism. The kcat value was pH-independent between pH 2.8 and 6.8, suggesting lack of ionizable groups in kinetic step(s) that limit the overall turnover of the enzyme...
February 16, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29449223/gmc-pushes-for-automatic-erasure-when-a-doctor-is-convicted-of-a-serious-crime
#17
Clare Dyer
No abstract text is available yet for this article.
February 15, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29440063/david-oliver-the-bawa-garba-case-doctors-and-the-gmc-what-next
#18
David Oliver
No abstract text is available yet for this article.
February 13, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29439155/gmc-accepts-another-test-as-proof-of-language-skills
#19
Abi Rimmer
No abstract text is available yet for this article.
February 9, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29439146/gmc-responds-to-concerns-raised-by-bawa-garba-case
#20
Charlie Massey
No abstract text is available yet for this article.
February 9, 2018: BMJ: British Medical Journal
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