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https://www.readbyqxmd.com/read/28704204/psychometric-analysis-of-the-swedish-version-of-the-general-medical-council-s-multi-source-feedback-questionnaires
#1
Jan-Eric Olsson, Fan Yang Wallentin, Eva Toth-Pal, Solvig Ekblad, Bo Christer Bertilson
Objectives: To determine the internal consistency and the underlying components of our translated and adapted Swedish version of the General Medical Council's multisource feedback questionnaires (GMC questionnaires) for physicians and to confirm which aspects of good medical practice the latent variable structure reflected. Methods: From October 2015 to March 2016, residents in family medicine in Sweden were invited to participate in the study and to use the Swedish version to perform self-evaluations and acquire feedback from both their patients and colleagues...
July 10, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28693082/-study-of-mumps-immunity-after-administrating-measles-mumps-rubella-vaccine-among-children-aged-2-7-years-old-in-jiangsu-province-in-2015
#2
Y B Liu, Y Hu, X Y Deng, Z G Wang, X Sun, P S Lu, H X Guo, F Y Tang, M H Zhou
Objective: To investigate the immunity to mumps after administrating measles-mumps-rubella vaccine (MMR) among children aged 2-7 years old in Jiangsu province in 2015. Methods: A total of 4 190 healthy children aged 2-7 years old, living in local places for at least 3 months, and having been vaccinated at least 1 dose MMR were recruited to the study from Wujin district of Changzhou city, Gaogang district of Taizhou city and Ganyu district of Lianyungang city by using stratified cluster random sampling method between September and November, 2015...
July 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28693011/comparaci%C3%A3-n-de-la-efectividad-de-ranibizumab-intrav%C3%A3-treo-para-el-tratamiento-del-edema-macular-diab%C3%A3-tico-en-ojos-vitrectomizados-y-no-vitrectomizados
#3
Yoshito Koyanagi, Shigeo Yoshida, Yoshiyuki Kobayashi, Yuki Kubo, Muneo Yamaguchi, Takahito Nakama, Shintaro Nakao, Yasuhiro Ikeda, Yuji Ohshima, Tatsuro Ishibashi, Kohhei Sonoda
Objetivo: Comparar la efectividad de ranibizumab intravítreo (RIV) para el tratamiento del edema macular diabético (EMD) en ojos con y sin vitrectomía previa. Procedimientos: Evaluamos de manera prospectiva la mejor agudeza visual corregida (MAVC) y el grosor macular central (GMC) tras el tratamiento con RIV durante 6 meses. Resultados: No se observaron diferencias significativas en la MAVC o GMC inicial en ninguno de los dos grupos. En el grupo no vitrectomizado (n = 15), los cambios medios en la MAVC y GMC hasta el sexto mes de tratamiento con respecto al valor inicial resultaron significativos (p < 0,01)...
July 11, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28681172/whither-surgical-quality-assurance-of-breast-cancer-surgery-surgical-margins-and-local-recurrence-after-paterson
#4
EDITORIAL
N J Bundred, J Thomas, J M J Dixon
The Kennedy report into the actions of the disgraced Breast Surgeon, Paterson focussed on issues of informed consent for mastectomy, management of surgical margins and raised concerns about local recurrence rates and the increasing emphasis on cosmesis after mastectomy for breast cancer. This article assesses whether Kennedy's recommendations apply to the UK as a whole and how to address these issues. New GMC advice on consent and newer nonevidenced innovations in immediate reconstruction have altered the level of informed consent required...
July 5, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28676559/a-third-of-junior-doctors-say-rota-gaps-have-worsened-their-training-gmc-finds
#5
Abi Rimmer
No abstract text is available yet for this article.
July 4, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28668953/iga-enhances-igf-1-mitogenic-activity-via-receptor-modulation-in-glomerular-mesangial-cells-implications-for-iga-induced-nephropathy
#6
Amal Al-Eisa, Gursev S Dhaunsi
BACKGROUND/AIM: Glomerulonephritis due to mesangial proliferation is responsible for renal dysfunction in IgA nephropathy (IgAN), however molecular mechanisms of pathogenesis are not well known. We examined the effect of IgA on Insulin-like Growth Factor-1 (IGF-1) activity, a potent mitogen with vital role in growth and development of children, and IGF-1 receptor (IGF-1R) in cultures of glomerular mesangial cells (GMC). METHODS: GMC were isolated from rat kidneys using sieving and enzymatic digestion of tissue homogenates, and cultured in RPMI 1640 medium...
June 27, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28659030/tongxinluo-inhibits-renal-fibrosis-in-diabetic-nephropathy-involvement-of-the-suppression-of-intercellular-transfer-of-tgf-formula-see-text-1-containing-exosomes-from-gecs-to-gmcs
#7
Xiao-Ming Wu, Yan-Bin Gao, Li-Ping Xu, Da-Wei Zou, Zhi-Yao Zhu, Xiao-Lei Wang, Wei-Jie Yao, Liang-Tao Luo, Yu Tong, Nian-Xiu Tian, Zhe-Ji Han, Wan-Yu Dang
Glomerular mesangial cells (GMCs) activation is implicated in the pathogenesis of diabetic nephropathy (DN). Our previous study revealed that high glucose (HG)-treated glomerular endothelial cells (GECs) produce an increased number of TGF-β1-containing exosomes to activate GMCs through the TGF-β1/Smad3 signaling pathway. We also identified that Tongxinluo (TXL), a traditional Chinese medicine, has beneficial effects on the treatment of DN in DN patients and type 2 diabetic mice. However, it remained elusive whether TXL could ameliorate renal structure and function through suppression of intercellular transfer of TGF-β1-containing exosomes from GECs to GMCs...
June 28, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28652392/bma-annual-meeting-gmc-must-recognise-that-a-lack-of-resources-puts-doctors-at-risk-of-mistakes-says-the-bma
#8
Abi Rimmer
No abstract text is available yet for this article.
June 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28651839/post-vaccination-serologic-testing-of-infants-born-to-hepatitis-b-surface-antigen-positive-mothers-in-4-provinces-of-china
#9
Fuzhen Wang, Guomin Zhang, Hui Zheng, Ning Miao, Liping Shen, Feng Wang, Pumei Dong, Fei Du, Chao Chen, Xiaoshu Zhang, Fuqiang Cui
OBJECTIVE: To evaluate prenatal maternal hepatitis B virus (HBV) screening and post-vaccination hepatitis B surface antigen (HBsAg) and antibody to hepatitis B surface antigen (anti-HBs) status and titers of babies born to HBsAg positive mothers, and to provide evidence for development of standard postvaccination serologic testing (PVST) strategies for babies born to HBsAg positive mothers in China. METHODS: In 2014, we conducted a baseline survey of HBV mother to child transmission (MTCT) interruption strategy implementation and PVST for babies born to HBsAg positive mothers after received 3 doses of hepatitis B vaccine (HepB) in 8 counties in 4 Provinces...
June 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28651399/-immune-response-to-one-booster-dose-of-inactivated-hepatitis-a-vaccine-in-college-students
#10
Z Liao, X W Feng, X E Liu, Y S Zhou, H R Wen, S H Peng, Y X Zhang, B Xu, H Zhuang, H Y Chen
Objective: To evaluate the safety and immunogenicity of one booster dose of inactivated hepatitis A vaccine in young adults. Methods: The subjects were selected from participants in the clinical trial of immunogenicity of inactivated and attenuated live hepatitis A vaccine in young adults. Eligible subjects were those who had received one dose of inactivated or attenuated hepatitis A vaccine, could be contacted and were sero-negative before primary vaccination. All qualified subjects were immunized with one booster dose of inactivated hepatitis A vaccine...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28627566/theoretical-study-of-one-electron-oxidized-salen-complexes-of-group-7-mn-iii-tc-iii-and-re-iii-and-group-10-metals-ni-ii-pd-ii-and-pt-ii-with-the-3d-rism-gmc-qdpt-method-localized-vs-delocalized-ground-and-excited-states-in-solution
#11
Shinji Aono, Masayuki Nakagaki, Shigeyoshi Sakaki
One-electron oxidized salen complexes of Mn(iii) and Ni(ii) were recently reported to be unique mixed-valence compounds. Their electronic structures are sensitive to the salen ligand and solvation. We systematically investigated a series of one-electron oxidized salen complexes of group 7 metals (Mn(iii), Tc(iii), and Re(iii)) and their group 10 analogues (Ni(ii), Pd(ii), and Pt(ii)) using the general multi-configuration reference quasi-degenerate perturbation theory (GMC-QDPT) which was combined with the three-dimensional reference interaction site model self-consistent field theory (3D-RISM-SCF) to incorporate the solvation effect...
June 28, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28627065/evaluation-of-an-in%C3%A2-vitro-system-to-simulate-equine-foregut-digestion-and-the-influence-of-acidity-on-protein-and-fructan-degradation-in-the-horse-s-stomach
#12
S Strauch, B Wichert, J M Greef, D Hillegeist, A Zeyner, A Liesegang
The aim of this study was to improve an in vitro system in order to gather optimized information on the digestion of different forages in the horse's upper gastrointestinal tract. Therefore, foregut digestion of several forages was simulated in vitro (Part 1). The effect of different pH values on in vitro fructan degradation of two selected grasses (Part 2) was tested subsequently. Part 1: We hypothesized that our system produces representative results simulating digestive processes in the upper alimentary tract, but neglects microbial fermentation...
June 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28600372/a-mixed-methods-evaluation-of-the-educational-supervision-agreement-for-wales
#13
Katie Louise Webb, Alison Bullock, Caroline Groves, Anton Gerhard Saayman
OBJECTIVES: In a bid to promote high-quality postgraduate education and training and support the General Medical Council's (GMC) implementation plan for trainer recognition, the Wales Deanery developed the Educational Supervision Agreement (EdSA). This is a three-way agreement between Educational Supervisors, Local Education Providers and the Wales Deanery which clarifies roles, responsibilities and expectations for all. This paper reports on the formative evaluation of the EdSA after 1 year...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28595358/reduced-antibody-response-to-infant-measles-vaccination-effects-based-on-type-and-timing-of-the-first-vaccine-dose-persist-after-the-second-dose
#14
Sara Carazo Perez, Gaston De Serres, Alexandre Bureau, Danuta M Skowronski
Background: The effect of age at first dose on the immunogenicity of a two-dose pediatric schedule of Measles-Mumps-Rubella (MMR) or MMR-Varicella (MMRV) vaccines was assessed in children born to mostly vaccinated mothers. Methods: Immunogenicity data among children given their first measles vaccine dose between 11 and 22 months of age were pooled from five randomized controlled trials conducted in Europe and the United States between 2004 and 2010. Measles antibody titers were measured by ELISA before/after each dose: geometric mean concentrations (GMCs) and the proportion sero-negative (GMC<150mIU/ml) were derived by age at first dose...
June 8, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28592091/-anti-hbs-persistence-after-revaccination-with-three-doses-of-hepatitis-b-vaccine-among-low-responder-infants-following-primary-vaccination-4-year-of-follow-up
#15
J J Lyu, B Y Yan, J Y Liu, Y Feng, W L Wu, X F Liang, F Q Cui, F Z Wang, G M Zhang, A Q Xu, L Zhang
Objective: Assess the 4-year antibody against hepatitis B surface antigen (anti-HBs) persistence after revaccination with 3-dose of hepatitis B vaccine (HepB) among low-responder infants following primary vaccination. Methods: According to stratified cluster sampling, a total of 4 147 infants were enrolled and primarily vaccinated with 5 μg HepB derived in Saccharomyces Cerevisiae (HepB-SC) at 0-1-6 months schedule from 75 towns of Jinan, Weifang, Yantai, Weihai prefectures, Shandong Province, China in Aug and Sep 2009...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28567431/rotavirus-vaccine-schedules-and-vaccine-response-among-infants-in-low-and-middle-income-countries-a-systematic-review
#16
REVIEW
Joann F Gruber, Lucinda M Gruber, Rachel Palmieri Weber, Sylvia Becker-Dreps, Michele Jonsson Funk
BACKGROUND: Rotavirus vaccine schedules may impact vaccine response among children in low- and middle-income countries (LMICs). Our objective was to review the literature evaluating the effects of monovalent (RV1) or pentavalent rotavirus vaccines schedules on vaccine response. METHODS: We searched PubMed, Web of Science, Embase, and ClinicalTrials.gov for eligible trials conducted in LMICs comparing ≥2 vaccine schedules and reporting immunologic response or efficacy...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28566282/gmc-wins-right-to-appeal-ruling-that-registrar-s-fitness-to-practise-was-not-impaired
#17
Clare Dyer
No abstract text is available yet for this article.
May 31, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28551912/-bacteria-without-borders-a-high-carriage-rate-of-antibiotic-resistant-bacteria-among-syrian-children-hospitalized-in-galilee-medical-center
#18
Diana Faour Kassem, Naama Shahar, Smadar Ocampo, Tarif Bader, Zeev Zonis, Daniel Glikman
INTRODUCTION: As the civil war in Syria enters its fifth year, the Israeli government continues to provide humanitarian aid to Syrian civilians in Israeli hospitals. Many wounded Syrian children are treated at the Galilee Medical Center (GMC). Due to the patients' incomplete medical history and increasing infection rates in Syria, contact isolation and screening cultures for multi-drug resistant bacteria (MDR's) are conducted upon admission for all Syrian children. AIMS: To describe the rate of MDR carriage in Syrian children and compare it to hospitalized Israeli children...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551903/-against-all-odds-promoting-research-clinical-development-and-medical-services-of-the-conflict-in-the-galilee-medical-center
#19
Jacob Bornstein
The Galilee Medical Center (GMC) is unique in several aspects. Firstly, in the clinical aspect: In recent years, led by the Director of Medical Center, Dr. Masad Barhoum, a considerable momentum of development has taken place to reduce health discrepancies between the center and the periphery. Despite the under- financing of the health system in the Galilee, the GMC opened new clinical departments, introduced advanced medical technology and key staff members were added. This approach is depicted in publications presented in the current issue...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28550084/postgraduate-training-will-be-more-flexible-under-new-standards-says-gmc
#20
Abi Rimmer
No abstract text is available yet for this article.
May 26, 2017: BMJ: British Medical Journal
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