E N Gerasimova, N V Perova
Cholesterol-acceptor and cholesterol-transport functions of high density lipoproteins appear to occur by means of the principle of selfregulation as these lipoproteins (particles) included a number of active units responsible for their biological function. These units were as follows: a) protein-lipid structure of surface monolayer of high density lipoprotein particles, which enables to intercalate the molecules of unesterified cholesterol, b) the enzymatic system, responsible for cholesterol esterification (lecithin-cholesterol acyltransferase--LCAT), involving the enzyme second substrate lecithin and activator apoprotein A-1, c) the system of nonenzymatic controlled transport of cholesterol esters, developed during the LCAT-reaction, involving the lipid-transport protein...
January 1985: Voprosy Medit︠s︡inskoĭ Khimii