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leg ulcer contact dermatitis

E Garval, J Plee, C Lesage, A Grange-Prunier, P Bernard, G Perceau
INTRODUCTION: Allergic contact dermatitis around chronic leg ulcers (CLU) is a common complication in patients presenting CLU and prolongs healing times. The aim of this study was to describe the rate of sensitization to modern dressings (MD) used in these patients and to assess whether there is a relation between the number of sensitizations and ulcer type, the time from onset of the ulcer, and patient age and gender. PATIENTS AND METHODS: We conducted a retrospective study at Reims University Hospital between 2010 and 2014 that included all patients with CLU of vascular etiology surrounded by eczematous lesions, and who had one of the patch-tests in the following 3 series: European baseline±leg ulcers±corticosteroids...
May 2018: Annales de Dermatologie et de Vénéréologie
Annie Price, Natalie M Stone, Keith G Harding
Allergic contact dermatitis commonly affects patients with chronic venous leg ulcers and can contribute to impaired wound healing. Many allergens have been identified, and despite the use of advanced dressings, the incidence of allergy has remained high. We discuss an unusual presentation of allergic contact dermatitis in a patient with a chronic wound. The patient's history was consistent with a recurrent venous leg ulcer, but on this occasion, the wound continued to deteriorate despite optimal treatment. This prompted further investigation, which included patch testing...
March 30, 2018: International Wound Journal
Reena Rai, Manjunath M Shenoy, Vishalakshi Viswanath, Nilendu Sarma, Imran Majid, Sunil Dogra
Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to the poor ulcer healing. To detect the various contact sensitisers in patients with venous leg ulcers through patch testing, patients from 6 centres across India with venous leg ulcers of longer than 6 weeks duration were enrolled for the study...
March 30, 2018: International Wound Journal
Liesbeth Gilissen, Sara Huygens, An Goossens
BACKGROUND: Natural ingredients have variable compositions, so their allergenic potencies may differ. OBJECTIVES: To retrospectively analyse subjects reacting to herbal remedies over the past 27 years, with the aim of (i) evaluating demographic characteristics and lesion locations, (ii) describing the frequencies of positive patch test reactions, (iii) identifing sensitization sources, and (iv) studying concomitant sensitivity. PATIENTS AND METHODS: In total, 15980 patients were patch tested between 1990 and 2016 with the European baseline series and/or other series, product(s) used, and, whenever possible, the respective ingredients...
March 2018: Contact Dermatitis
C Erfurt-Berge, V Mahler
No abstract text is available yet for this article.
2017: Journal of Investigational Allergology & Clinical Immunology
Cornelia Erfurt-Berge, Johannes Geier, Vera Mahler
BACKGROUND: Patients with lower leg dermatitis, chronic venous insufficiency or chronic leg ulcers have a high prevalence of contact sensitization. OBJECTIVES: To identify the current spectrum of contact allergens in these patients. PATIENTS AND METHODS: Data of the Information Network of Departments of Dermatology on 5264 patients with the above diagnoses from the years 2003 to 2014 (study group) were compared with data on 4881 corresponding patients from 1994 to 2003 (historical control group) and with a current control group without these diagnoses (n = 55 510)...
September 2017: Contact Dermatitis
A Massimiliano D'Erme, M Iannone, V Dini, M Romanelli
OBJECTIVE: Contact allergies can occur frequently in patients with chronic leg ulcers (CLUs), even in those with a short duration of ulcerative disease. The wide spectrum of therapeutic products promotes development of the delayed type of hypersensitivity and continuous changes in the allergens pattern, which make the diagnosis and treatment extremely difficult in many cases. A prompt diagnosis and treatment of allergic contact dermatitis (ACD) in patients suffering from CLUs is very important for a best clinical outcome of these two common diseases...
September 2016: Journal of Wound Care
Caterina Foti, Paolo Romita, Grazia Ettorre, Gianni Angelini, Domenico Bonamonte
No abstract text is available yet for this article.
June 2016: Contact Dermatitis
V Mahler
The percentage of seniors (> 65 years of age) in the general population continues to rise. Their sensitization profile may be influenced by lifelong work-related and nonwork-related exposures and comorbidities requiring local or systemic treatment. Recent analysis of the IVDK (Information Network of Departments of Dermatology) cohort concerning the most frequently recognized contact allergens in the age group above 65 (2009-2013: N = 14,841) revealed significant differences compared to the age group up to 65 years of age...
September 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Ferda Artüz, Emrah Yılmaz, Seray Külcü Çakmak, Arife Polat Düzgün
The aim of our study is to identify the allergens in patients with leg ulcers who have contact dermatitis surrounding the skin of the ulcer and compare them with a control group consisting of patients with lower extremity contact dermatitis. A total of 40 patients with chronic leg ulcers (CLU) and contact dermatitis around the skin of ulcer were included in the study. As a control group, 20 patients with contact dermatitis of lower extremity without leg ulcers were included. The patient and control groups were patch tested with 37 allergens of the European Standard Series...
December 2016: International Wound Journal
Ruth Jones, Helen M Horn
Contact dermatitis results from skin contact with an exogenous substance. It can be caused by direct contact, airborne particles, vapours or light. Individuals of any age can be affected. The two most common variants are irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD). ICD is more common and has a worse prognosis. Other less common forms of contact dermatitis include photocontact allergy and, in food handlers, protein contact dermatitis. ICD is a form of eczema and is induced by direct inflammatory pathways without prior sensitisation...
June 2014: Practitioner
Regina Renner, Jan C Simon, Regina Treudler
BACKGROUND: Patients with chronic leg ulcers typically experience contact allergy to topical treatments. Although declared as hypoallergenic, modern wound dressings have caused several reported cases of contact allergy. OBJECTIVE: The aim of the study was to evaluate any allergenic potential of modern wound dressings in patients with leg ulcers. METHODS: Seventy-one patients were included in our prospective observation. Patch tests were performed with a selection of 10 modern wound dressings and with selected allergens according to series of the German Contact Dermatitis Research Group (DKG)...
March 2013: Dermatitis
(no author information available yet)
OBJECTIVE: The objective of the MAS evidence review was to conduct a systematic review of the available evidence on the safety, effectiveness, durability and cost-effectiveness of endovascular radiofrequency ablation (RFA) for the treatment of primary symptomatic varicose veins. BACKGROUND: The Ontario Health Technology Advisory Committee (OHTAC) met on August 26th, 2010 to review the safety, effectiveness, durability, and cost-effectiveness of RFA for the treatment of primary symptomatic varicose veins based on an evidence-based review by the Medical Advisory Secretariat (MAS)...
2011: Ontario Health Technology Assessment Series
Heiko Poppe, Lidia Marilia Poppe, Eva-B Bröcker, Axel Trautmann
BACKGROUND: There are myriads of potentially irritant agents causing acute irritant contact dermatitis. In the large majority of cases, dermatitis is mild to moderate, and patients do not need hospitalization. However, some agents or special circumstances may cause severe dermatitis requiring more intensive therapy. OBJECTIVES: The aim of this study was to evaluate causative agents of severe acute irritant contact dermatitis requiring hospitalization. METHODS: In this single-centre observational cohort study, we included 54 consecutive patients presenting with signs and symptoms of acute irritant contact dermatitis for which hospitalization was necessary...
February 2013: Contact Dermatitis
Aistė Beliauskienė, Skaidra Valiukevičienė, Brigita Sitkauskienė, Axel Schnuch, Wolfgang Uter
BACKGROUND AND OBJECTIVE: The pattern of contact sensitization among patients with chronic leg ulcers depends on the local practice of wound treatment along with demographic and clinical confounders. The study was aimed at revealing the associations between chronic leg ulcers and contact sensitization. MATERIAL AND METHODS: Between 2006 and 2008, 35 patients with chronic leg ulcers and surrounding dermatitis and 59 patients with contact dermatitis of the lower leg or foot were prospectively recruited at the Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences...
2011: Medicina
Juan García-Gavín, Ruth Lissens, Ann Timmermans, An Goossens
BACKGROUND: Isopropyl alcohol is a secondary alcohol, a structural isomer of propanol, that is widely used as an industrial solvent and as a preservative and antiseptic in the clinical environment. It is known to be a mild irritant for the eyes and mucous membranes, but is considered to be a weak and infrequent sensitizer. OBJECTIVES: To show that isopropyl alcohol should be considered as a potential allergen in patients with eczema who have contact with this substance...
August 2011: Contact Dermatitis
Rodrigo Carvalho, Paula Maio, Cristina Amaro, Raquel Santos, Jorge Cardoso
Hydrogels contain modified carboxymethylcellulose polymer together with propylene glycol as known components. Nowadays, they are common agents used in the treatment of leg ulcer patients, and a possible cause of allergic contact dermatitis. However in the published data, not all the patients with positive patch tests to hydrogels were sensitized to propylene glycol, remaining some allergens to be identified. The authors describe two leg ulcer patients sensitized for different commercial available hydrogels tested "as is", with concomitant patch tested positivity to imidazolidinyl urea (IU) and diazolidinyl urea (DU)...
December 2011: Cutaneous and Ocular Toxicology
Anna Balato, Nicola Balato, Luisa Di Costanzo, Fabio Ayala
Contact dermatitis from irritant and allergic sources is the reason for 6% to 10% of all dermatologic visits with considerable morbidity and economic impact. Allergic contact dermatitis is a T-cell-mediated inflammatory reaction and develops in predisposed individuals as a consequence of environmental exposure to allergens. Aging is correlated with the rate and type of contact sensitization because of "immunosenescence." The number of old people is growing around the world. This contribution reviews the main findings from published epidemiologic studies on contact allergy in elderly populations...
January 2011: Clinics in Dermatology
S Reich-Schupke, J Kurscheidt, C Appelhans, A Kreuter, P Altmeyer, M Stücker
BACKGROUND: Patients with leg ulcers often have contact sensitizations. Modern wound care products claim low allergic potential. OBJECT: To analyze the patch test results in leg ulcer patients with focus on modern care wound products. MATERIAL AND METHODS: 95 leg ulcer patients were tested with the standard German patch test series as well as frequently used wound care products. RESULTS: 61% of the patients had at least one positive reaction...
July 2010: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Alena Machovcova
Chromium is widely used in various industries including construction sector. Skin contact with cement has been associated with allergic or irritant contact dermatitis. Contact dermatitis is one of the most frequently reported health problems among construction workers. Irritant contact dermatitis from cement ranges from cement burns to cumulative irritant contact dermatitis. Cement burns are rarely reported and are considered a severe form of acute irritant contact dermatitis. They are associated with amateur user working in a short ready-mix time-frame with poor protective measures...
2010: Industrial Health
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