Sangeetha Mohan, Lekshmy Krishnan, Nithya Madhusoodanan, Anjali Sobha, Renjitha Jalaja, Alaganandam Kumaran, Naveen Vankadari, Jayamurthy Purushothaman, Sasidhar B Somappa
Prolonged inflammation leads to the genesis of various inflammatory diseases such as atherosclerosis, cancer, inflammatory bowel disease, Alzheimer's, etc. The uncontrolled inflammatory response is characterized by the excessive release of pro-inflammatory mediators such as nitric oxide (NO), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-1alpha (IL-1α), and inflammatory enzymes such as cyclooxygenase-2 (COX-2). Hence, the downregulation of these inflammatory mediators is an active therapy to control aberrant inflammation and tissue damage...
March 17, 2024: Journal of Agricultural and Food Chemistry