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https://www.readbyqxmd.com/read/28928989/an-unusual-case-of-recurrent-hypersensitivity-reaction-associated-with-kounis-like-acute-coronary-syndrome
#1
Shanker Kundumadam, Vivek Reddy, Sagar Mallikethi Reddy, Pradeep Kathi, Aiden Abidov
There have been multiple reports of allergic reactions associated with acute coronary syndromes. This has been classically described as Kounis syndrome. We present an unusual case of 70-year-old male with multiple prior hypersensitivity reactions and history of coronary artery bypass grafting who presented recurrent episode of severe angioedema and anaphylaxis. He responded to epinephrine but subsequently developed a non-ST elevation myocardial infarction with worsening heart failure. Our case is unique in that, unlike classic Kounis syndrome, the acute coronary event in this case did not present concurrently with the allergic reaction; rather it took nearly 48 hours to present...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28882939/wasp-sting-induced-stemi-with-complete-coronary-artery-occlusion-a-case-of-kounis-syndrome
#2
Benjamin Cross, Tawfiqur Rahman Choudhury, Mark Hindle, Gavin Galasko
A 45-year-old previously healthy man with minimal coronary artery disease on imaging presented with an acute MI after sustaining a wasp sting following previous non-eventful exposures throughout his life. This is the first case of Kounis syndrome with optical coherence tomography imaging and proven IgE wasp venom hypersensitivity. The Hymenoptera venom is composed of allergenic proteins and vasoactive amines which are responsible for venom toxicity. This patient also has a history of atopy giving a predisposition for developing IgE-mediated allergic reactions...
September 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28870153/myocardial-infarction-during-anaphylaxis-in-a-young-healthy-male-with-normal-coronary-arteries-is-epinephrine-the-culprit
#3
W D Jayamali, H M M T B Herath, Aruna Kulathunga
BACKGROUND: Anaphylaxis is an acute, potentially fatal medical emergency. Myocardial injury or infarction in the setting of an anaphylaxis can be due the anaphylaxis itself, when it is known as Kounis syndrome or it can also be due to the effect of epinephrine treatment. Epinephrine is considered as the cornerstone in management of anaphylaxis. Myocardial infarction secondary to therapeutic doses of adrenaline is a rare occurrence and only a few cases have been reported in literature...
September 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28841642/modeling-zoonotic-cutaneous-leishmaniasis-incidence-in-central-tunisia-from-2009-2015-forecasting-models-using-climate-variables-as-predictors
#4
Khouloud Talmoudi, Hedia Bellali, Nissaf Ben-Alaya, Marc Saez, Dhafer Malouche, Mohamed Kouni Chahed
Transmission of zoonotic cutaneous leishmaniasis (ZCL) depends on the presence, density and distribution of Leishmania major rodent reservoir and the development of these rodents is known to have a significant dependence on environmental and climate factors. ZCL in Tunisia is one of the most common forms of leishmaniasis. The aim of this paper was to build a regression model of ZCL cases to identify the relationship between ZCL occurrence and possible risk factors, and to develop a predicting model for ZCL's control and prevention purposes...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28756913/kounis-syndrome-or-allergic-infarction-a-relatively-unknown-entity
#5
M I Barrionuevo Sánchez, M J Corbí Pascual, J G Córdoba Soriano, C Ramírez Guijarro, S Calero Nuñez, G Gallego Sánchez
No abstract text is available yet for this article.
July 27, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28735972/pyrimidine-metabolism-in-schistosomes-a-comparison-with-other-parasites-and-the-search-for-potential-chemotherapeutic-targets
#6
REVIEW
Mahmoud H El Kouni
Schistosomes are responsible for the parasitic disease schistosomiasis, an acute and chronic parasitic ailment that affects >240 million people in 70 countries worldwide. It is the second most devastating parasitic disease after malaria. At least 200,000 deaths per year are associated with the disease. In the absence of the availability of vaccines, chemotherapy is the main stay for combating schistosomiasis. The antischistosomal arsenal is currently limited to a single drug, Praziquantel, which is quite effective with a single-day treatment and virtually no host-toxicity...
November 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28694403/interesting-presentation-of-kounis-syndrome-secondary-to-amoxicillin-clavulanate-use-coronary-vasospasm-and-simultaneous-appropriate-implantable-defibrillator-shock
#7
Uğur Canpolat, Duygu Koçyiğit, Kudret Aytemir
Kounis syndrome (KS) is defined as concurrent acute coronary syndrome and allergic or hypersensitivity reactions. Despite being increasingly reported, it is still an underdiagnosed entity. Several medications are already known to result in KS. Amoxicillin/clavulanic acid is a frequently used antibiotic, and its use has been linked with KS. The aim of the present report was to draw attention to rare clinical manifestation of KS following peroral amoxicillin/clavulanate use.
July 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28583235/type-1-kounis-syndrome-in-a-patient-with-idiopathic-anaphylaxis
#8
Monica Sandhu, Jason Casselman, Brian Peppers, Haig Tcheurekdjian, Robert W Hostoffer
Anaphylactic insults that cause cardiovascular signs and symptoms have been defined as Kounis syndrome, which has been associated with specific triggered anaphylactic reactions. Kounis syndrome has not been described in patients with no evidence of coronary artery disease (type I Kounis) in a scenario of idiopathic anaphylaxis. We reported a case of a 65-year-old white woman with no evidence of coronary artery disease who experienced two myocardial infarctions on separate occasions attributable to idiopathic anaphylaxis...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28580091/effects-of-sugammadex-on-the-coronary-circulation-direct-effects-on-coronary-vessels-or-hypersensitivity-kounis-syndrome
#9
COMMENT
Hong-Seuk Yang, Ha-Jung Kim, Wonuk Koh
No abstract text is available yet for this article.
June 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28570230/kounis-syndrome-is-it-really-a-takotsubo-like-syndrome
#10
O S Kotsiou, K I Xirogiannis, K I Gourgoulianis
No abstract text is available yet for this article.
June 2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28559712/lethal-case-of-vipera-bersus-bite
#11
Nicholas G Kounis, Ioanna Koniari, George Hahalis
No abstract text is available yet for this article.
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28532437/management-of-kounis-syndrome-two-case-reports
#12
Majdi Omri, Hajer Kraiem, Olfa Mejri, Mounir Naija, Naoufel Chebili
BACKGROUND: Kounis syndrome corresponds to the occurrence of myocardial injury following an allergic insult. This syndrome is infrequent, and is not well known. In consequence, it is usually misdiagnosed leading to inappropriate treatment. The current literature is limited to case studies and there are no international recommendations concerning this topic. CASE PRESENTATION: We discussed, through two case reports, the clinical presentation and the management of a 60-year-old North African man and a 45-year-old North African man presenting with chest pain suggesting acute coronary syndrome following anaphylactic reaction...
May 23, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28530026/kounis-syndrome-is-it-rare-or-is-it-underdiagnosed
#13
Bruno Limpo, Ángel Morales Martínez-de-Tejada
No abstract text is available yet for this article.
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28529288/kounis-syndrome-not-induced-but-prevented-by-the-implantation-of-a-drug-eluting-stent-a-case-report
#14
Kadriye Terzioğlu, Dane Ediger, Raziye Tülümen Öztürk, Eda Durmuş, Mehmet Fethi Alışır
No abstract text is available yet for this article.
May 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28523173/thrombotic-responses-to-coronary-stents-bioresorbable-scaffolds-and-the-kounis-hypersensitivity-associated-acute-thrombotic-syndrome
#15
REVIEW
Nicholas G Kounis, Ioanna Koniari, Anastasios Roumeliotis, Grigorios Tsigas, George Soufras, Nicholas Grapsas, Periklis Davlouros, George Hahalis
Percutaneous transluminal coronary angioplasty with coronary stent implantation is a life-saving medical procedure that has become, nowadays, the most frequent performed therapeutic procedure in medicine. Plain balloon angioplasty, bare metal stents, first and second generation drug-eluting stents, bioresorbable and bioabsorbable scaffolds have offered diachronically a great advance against coronary artery disease and have enriched our medical armamentarium. Stented areas constitute vulnerable sites for endothelial damage, endothelial dysfunction, flow turbulence, hemorheologic changes, platelet dysfunction, coagulation changes and fibrinolytic disturbances...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28521972/coronary-vasospasm-associated-with-5-fluorouracil-chemotherapy-cardiac-toxicity-or-cardiac-hypersensitivity
#16
Nicholas G Kounis, Ioanna Koniari, Nicholas Patsouras, Nicholas Koutsogiannis, Dimitrios Velissaris, George Soufras, George Hahalis
No abstract text is available yet for this article.
May 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28511332/-kounis-sysdrome-secondary-to-crucian-allergy-a-case-report
#17
J J Guo, J Y Liu, S L Wang
No abstract text is available yet for this article.
May 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28457118/kounis-syndrome-acute-st-segment-elevation-myocardial-infarction-following-allergic-reaction-to-amoxicillin
#18
Dante Antonelli, Ehud Rozner, Yoav Turgeman
No abstract text is available yet for this article.
January 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28449974/in-hospital-acute-myocardial-infarction-a-case-of-type-ii-kounis-syndrome
#19
Rita Marinheiro, Pedro Amador, Filipa Semedo, Catarina Sá, Tatiana Duarte, Sara Gonçalves, Filipe Seixo, Rui Caria
Kounis syndrome (KS) is the coincidental occurrence of acute coronary syndrome (ACS) and anaphylactic or allergic insult. It results from mast cell degranulation with subsequent release of numerous inflammatory mediators, leading to coronary vasospasm or atheromatous plaque rupture. Diagnosis is clinical and based on the temporal relationship between the two events. Despite the growing number of reported cases, especially in southern Europe, the lack of awareness of this association may lead to under-reporting in Portugal...
May 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28428933/cardiac-arrest-caused-by-nafamostat-mesilate-kounis-syndrome-in-the-dialysis-room
#20
COMMENT
Ioanna Koniari, Nicholas G Kounis
No abstract text is available yet for this article.
March 2017: Kidney Research and Clinical Practice
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