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Neuroanesthesia ketamine

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https://www.readbyqxmd.com/read/23409639/rethinking-the-paradigm-evaluation-of-ketamine-as-a-neurosurgical-anesthetic
#1
REVIEW
Eric D Bowles, Michele E Gold
Although anesthetists have long assumed that ketamine's role in neuroanesthesia is limited because of its association with increased intracranial pressure, this article presents a review of recent clinical literature suggesting otherwise. When ketamine is used as an adjuvant anesthetic agent along with mechanical ventilation to maintain normocapnia, ketamine does not have adverse cerebral hemodynamic effects. Furthermore, ketamine possesses a unique pharmacologic profile that provides analgesia, bronchodilation, and sympathetic stimulation, thereby reducing patients' vasoactive agent requirements...
December 2012: AANA Journal
https://www.readbyqxmd.com/read/12505959/s-ketamine-attenuates-myogenic-motor-evoked-potentials-at-or-distal-to-the-spinal-alpha-motoneuron
#2
Kai-Michael Scheufler, Christof Thees, Joachim Nadstawek, Josef Zentner
UNLABELLED: We investigated the effect of S(+)-ketamine on spinal cord evoked potentials (ESCPs) and myogenic motor-evoked potentials after electrical stimulation of the motor cortex in a rabbit model. This study was designed to characterize the relationship between ESCP characteristics and corresponding changes in compound muscle action potentials (CMAPs) derived from fore and hind limbs. Direct (D) and indirect (I) corticospinal volleys (ESCP) from the upper and lower thoracic spinal cord, recorded by two bipolar epidural electrodes, were assessed during IV administration of 0...
January 2003: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/7653791/-propofol-for-neuroanesthesia
#3
REVIEW
P Ravussin, S Strebel
The quality, result, and prognosis of neurosurgery relies heavily on the anaesthetic technique. Many different classes of drugs have been used during neurosurgical anaesthesia. This article reviews the use of intravenous (IV) propofol as an alternative to volatile anaesthetic techniques. Anaesthesia requirements for neurosurgical procedures are elaborated upon in the first part of the article. The priority of neuroanaesthesia is to preserve neuronal function by avoiding complications such as hypoxia, hypercarbia, and cardiovascular instability...
June 1995: Der Anaesthesist
https://www.readbyqxmd.com/read/1843831/influence-of-anesthesia-on-cerebral-blood-flow-and-cerebral-metabolism-an-overview
#4
H Van Aken, J Van Hemelrijck
Knowledge of the influence of anesthetics on cerebral blood flow and metabolism is the key to both safe neuroanesthesia practice and understanding the possible neuroprotection offered by these agents. In this paper the authors summarize recent data from the literature. All volatile anesthetics (except for nitrous oxide) produce a dose dependent decrease in cerebral metabolism. The changes in cerebral blood flow depend on the changes in cerebral metabolism and on direct vasodilatory effects; frequently volatile anesthetics increase cerebral blood flow...
1991: Agressologie
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