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https://www.readbyqxmd.com/read/28294968/nutrients-and-the-pancreas-an-epigenetic-perspective
#1
REVIEW
Andee Weisbeck, Rick J Jansen
Pancreatic cancer is the fourth most common cause of cancer-related deaths with a dismal average five-year survival rate of six percent. Substitutional progress has been made in understanding how pancreatic cancer develops and progresses. Evidence is mounting which demonstrates that diet and nutrition are key factors in carcinogenesis. In particular, diets low in folate and high in fruits, vegetables, red/processed meat, and saturated fat have been identified as pancreatic cancer risk factors with a proposed mechanism involving epigenetic modifications or gene regulation...
March 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28294105/breath-acetone-as-a-potential-marker-in-clinical-practice
#2
Vera Ruzsanyi, Miklós Kalapos
In recent decades, two facts have changed the opinion of researchers about the function of acetone in humans. Firstly, it has turned out that acetone cannot be regarded as simply a waste product of metabolism, because there are several pathways in which acetone is produced or broken down. Secondly, methods have emerged making possible its detection in exhaled breath, thereby offering an attractive alternative to investigation of blood and urine samples. From a clinical point of view the measurement of breath acetone levels are important, but there are limitations to its wide application...
March 15, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28293621/development-of-the-physical-activity-and-your-nutrition-for-cancer-pync-smartphone-app-for-preventing-breast-cancer-in-women
#3
Steven S Coughlin, Gina M Besenyi, Deborah Bowen, Gianluca De Leo
BACKGROUND: In the U.S., breast cancer accounts for more cancer deaths in women than any site other than lung cancer. Based upon attributable risks, about 30-35% of breast cancers could potentially be prevented by addressing obesity, physical inactivity, increased alcohol consumption, and carcinogenic exposures such as hormone replacement therapy (HRT). We need methods of reducing women's risks of this disease that are attractive and easy to use, widely accessible to diverse women, and able to be easily amended to account for new research...
2017: MHealth
https://www.readbyqxmd.com/read/28287324/the-effect-of-a-home-delivery-meal-service-of-energy-and-protein-rich-meals-on-quality-of-life-in-malnourished-outpatients-suffering-from-lung-cancer-a-randomized-controlled-trial
#4
Eva Leedo, Josephine Gade, Sabrina Granov, Anders Mellemgaard, Tobias Wirenfeldt Klausen, Katrine Rask, Arne Astrup
Undernutrition is prevalent in cancer patients and associated with increased incidence of complications and mortality. We investigated the effects of a home delivery meal service, providing a selection of energy-dense, protein-rich meals, on quality of life (QoL) in malnourished lung cancer patients. Forty lung cancer patients with nutritional risk score ≥3 (NRS-2002) were randomized to control or intervention. The intervention group was offered energy- and protein-rich main meals and snacks, delivered 3 times per week...
April 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28272400/vegetarian-diet-as-a-risk-factor-for-symptomatic-gallstone-disease
#5
T J McConnell, P N Appleby, T J Key
BACKGROUND/OBJECTIVES: Previous small studies have shown either no difference or a lower risk of symptomatic gallstone disease in vegetarians than in non-vegetarians. This study examined the incidence of symptomatic gallstone disease in a cohort of British vegetarians and non-vegetarians, and investigated the associations between nutrient intake and risk of symptomatic gallstone disease. SUBJECTS/METHODS: The data were analysed from 49 652 adults enroled in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Oxford study, one-third of whom were vegetarian...
March 8, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28264783/dietary-lipids-differentially-modulate-the-initiation-of-experimental-breast-carcinogenesis-through-their-influence-on-hepatic-xenobiotic-metabolism-and-dna-damage-in-the-mammary-gland
#6
Miguel Ángel Manzanares, Cristina de Miguel, M Carme Ruiz de Villa, Regina M Santella, Eduard Escrich, Montserrat Solanas
Breast cancer is the most common malignancy among women worldwide. In addition to reproductive factors, environmental factors such as nutrition and xenobiotic exposure have a role in the etiology of this malignancy. A stimulating and a potentially protective effect on experimental breast cancer has been previously described for high corn oil and high extra-virgin olive oil diets, respectively. This work investigates the effect of these lipids on the metabolism of 7,12-dimethylbenz(a)anthracene (DMBA), a polycyclic aromatic hydrocarbon that can initiate carcinogenesis and its consequences in an experimental rat breast cancer model...
February 10, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28264695/the-feasibility-of-the-prostate-cancer-evidence-of-exercise-and-nutrition-trial-prevent-dietary-and-physical-activity-modifications-a-qualitative-study
#7
Ellie Shingler, Lucy Hackshaw-McGeagh, Luke Robles, Raj Persad, Anthony Koupparis, Edward Rowe, Constance Shiridzinomwa, Amit Bahl, Richard M Martin, J Athene Lane
BACKGROUND: There is increasing evidence that low levels of physical activity and diets low in fruit and vegetables and high in meat and dairy products are risk factors for prostate cancer disease progression. The Prostate cancer: Evidence of Exercise and Nutrition Trial (PrEvENT) aimed to assess a diet and physical activity intervention in men undergoing radical prostatectomy for localized prostate cancer. The trial included a qualitative component to explore the experiences of men participating in the trial in order to understand the acceptability of the intervention and data collection methods...
March 7, 2017: Trials
https://www.readbyqxmd.com/read/28261340/integrative-oncology-physician-consultations-at-a-comprehensive-cancer-center-analysis-of-demographic-clinical-and-patient-reported-outcomes
#8
Gabriel Lopez, Jennifer McQuade, Lorenzo Cohen, Jane T Williams, Amy R Spelman, Bryan Fellman, Yisheng Li, Eduardo Bruera, Richard T Lee
Background: Integrative oncology (IO) is a relatively new field that seeks to bring evidence-based, non-conventional approaches into conventional oncology care in a coordinated and safe manner. Though complementary and alternative medicine (CAM) are highly utilized by cancer patients, little is known about the characteristics of patients seeking IO consultation. Methods: Patients presenting for an outpatient IO consultation completed a CAM use questionnaire, Measure Yourself Concerns and Wellbeing (MYCaW), Edmonton Symptom Assessment Scale (ESAS), Quality of Life Short Form 12 (SF-12), and post-consultation satisfaction item...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28247857/adherence-to-a-healthy-nordic-food-index-and-risk-of-myocardial-infarction-in-middle-aged-danes-the-diet-cancer-and-health-cohort-study
#9
V B Gunge, I Andersen, C Kyrø, C P Hansen, C C Dahm, J Christensen, A Tjønneland, A Olsen
BACKGROUND/OBJECTIVES: For decades, the Mediterranean diet has been in focus regarding healthy eating as it has been associated with reduced risk of non-communicable diseases. Less interest has been given to health benefits of other regional diets. The aim of the present study was to assess whether adherence to a healthy Nordic food index was associated with lower risk of myocardial infarction (MI) among middle-aged Danes. SUBJECTS/METHODS: Data were obtained from the Danish Diet, Cancer and Health cohort study of 57 053 men and women aged 50-64 years recruited between 1993 and 1997...
March 1, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28220328/the-provision-of-dietary-and-physical-activity-advice-for-men-diagnosed-with-prostate-cancer-a-qualitative-study-of-the-experiences-and-views-of-health-care-professionals-patients-and-partners
#10
Eileen Sutton, Lucy E Hackshaw-McGeagh, Jonathan Aning, Amit Bahl, Anthony Koupparis, Raj Persad, Richard M Martin, J Athene Lane
PURPOSE: To explore the views and experiences of health care professionals (HCPs), men diagnosed with localised prostate cancer and their partners about the provision of advice on diet and physical activity after diagnosis and treatment for localised prostate cancer. METHODS: Semi-structured in-depth interviews with ten HCPs (Consultant Urological Surgeons, Uro-Oncology Clinical Nurse Specialists and Allied Health Professionals: see Table 1) and sixteen men diagnosed with localised prostate cancer and seven of their partners...
February 20, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28205223/abdominal-adiposity-is-not-a-mediator-of-the-protective-effect-of-mediterranean-diet-on-colorectal-cancer
#11
Francesca Fasanelli, Daniela Zugna, Maria Teresa Giraudo, Vittorio Krogh, Sara Grioni, Salvatore Panico, Amalia Mattiello, Giovanna Masala, Saverio Caini, Rosario Tumino, Graziella Frasca, Veronica Sciannameo, Fulvio Ricceri, Carlotta Sacerdote
Adherence to the Mediterranean diet (MD) has a preventive effect on colorectal cancer (CRC). Several biological mechanisms have been hypothesized to explain this effect, but the involvement of clinical mediators has not been experimentally proven. We examined the role of abdominal adiposity (i.e. waist-to-hip ratio, WHR) as a potential mediator of the relationship between the MD and CRC in the Italian centres of the European Prospective Investigation into Cancer and Nutrition. We evaluated the effect of the Italian Mediterranean Index (IMI) on WHR and of WHR on CRC risk...
February 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28176776/dietary-intake-of-whole-grains-and-plasma-alkylresorcinol-concentrations-in-relation-to-changes-in-anthropometry-the-danish-diet-cancer-and-health-cohort-study
#12
C Kyrø, M Kristensen, M U Jakobsen, J Halkjær, R Landberg, Hb As Bueno-de-Mesquita, J Christensen, I Romieu, A Tjønneland, A Olsen
BACKGROUND/OBJECTIVES: Whole grain intake has been associated with a small but significant lower body weight gain in observational studies, but there is limited knowledge about the associations with specific whole grain types. The objective was to investigate the association between whole grains, different sources of whole grains and biomarkers of whole grain intake (alkylresorcinols) in relation to subsequent changes in waist circumference (WC) and body weight. SUBJECTS/METHODS: Cohort study of 57 053 participants with baseline information on whole grain intake from questionnaires (FFQ) and biomarkers of whole grain rye and wheat intake, plasma alkylresorcinols, for a subset...
February 8, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28176669/effects-of-carotenoids-on-health-are-all-the-same-results-from-clinical-trials
#13
Arrigo F G Cicero, Alessandro Colletti
BACKGROUND: Oxidative stress is implicated in the pathogenesis of a lot of age-related pathologies and some types of cancers. Carotenoids have shown antioxidant properties, due to the ability to quench singlet oxygen and to scavenge free radicals that may prevent and treat a wide range of chronic diseases. The aim of this review is to discuss the clinical evidence present in literature about the effects of carotenoids on human health and to evaluate their effectiveness in the prevention and treatment of many chronic diseases...
February 6, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28173966/nutrition-interventions-in-patients-with-gynecological-cancers-requiring-surgery
#14
REVIEW
Andreas Obermair, Marko Simunovic, Liz Isenring, Monika Janda
OBJECTIVE: Including developing countries, between 20 and 88% of gynecological oncology patients may present with at least mild malnutrition at diagnosis. Significant morbidity and mortality is attributed to malnutrition. Here we reviewed randomized clinical trials of nutritional interventions used to achieve early return to oral diet, enhance recovery from surgery and reduce adverse events in gynecological cancer patients undergoing surgery. METHODS: Ebscohost (CINAHL+Medline+PsycINFO), Cochrane, Embase, PubMed and Scopus databases were searched for articles published from 2000 onwards...
February 4, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28170373/mediterranean-diet-and-risk-of-pancreatic-cancer-in-the-european-prospective-investigation-into-cancer-and-nutrition-cohort
#15
Esther Molina-Montes, María-José Sánchez, Genevieve Buckland, H B As Bueno-de-Mesquita, Elisabete Weiderpass, Pilar Amiano, Petra A Wark, Tilman Kühn, Verena Katzke, José María Huerta, Eva Ardanaz, José Ramón Quirós, Aurélie Affret, Mathilde His, Marie-Christine Boutron-Ruault, Petra H Peeters, Weimin Ye, Malin Sund, Heiner Boeing, Khalid Iqbal, Bodil Ohlsson, Emily Sonestedt, Anne Tjønneland, Kristina En Petersen, Ruth C Travis, Guri Skeie, Claudia Agnoli, Salvatore Panico, Domenico Palli, Rosario Tumino, Carlotta Sacerdote, Heinz Freisling, Inge Huybrechts, Kim Overvad, Antonia Trichopoulou, Christina Bamia, Effie Vasilopoulou, Nick Wareham, Kay-Tee Khaw, Amanda J Cross, Heather A Ward, Elio Riboli, Eric J Duell
BACKGROUND: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. METHODS: Over half a million participants from 10 European countries were followed up for over 11 years, after which 865 newly diagnosed exocrine pancreatic cancer cases were identified...
March 14, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28166841/long-term-associations-between-inflammatory-dietary-scores-in-relation-to-long-term-c-reactive-protein-status-measured-12-years-later-findings-from-the-suppl%C3%A3-mentation-en-vitamines-et-min%C3%A3-raux-antioxydants-su-vi-max-cohort
#16
Chantal Julia, Karen E Assmann, Nitin Shivappa, James R Hebert, Michael D Wirth, Serge Hercberg, Mathilde Touvier, Emmanuelle Kesse-Guyot
Chronic low-grade inflammation has been recognised as a key underlying mechanism for several chronic diseases, including cancer and CVD. Nutrition represents a host of key modifiable factors that influence chronic inflammation. Dietary inflammatory scores were developed to assess the inflammatory potential of the diet and have been associated with inflammatory biomarkers in cross-sectional and short-term longitudinal studies. The objective of this study was to investigate the relationship between the dietary inflammatory index (DII), the alternate dietary inflammatory index (ADII) and long-term C-reactive protein (CRP)...
February 7, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28165394/socio-demographic-determinants-of-diet-quality-in-australian-adults-using-the-validated-healthy-eating-index-for-australian-adults-heifa-2013
#17
Amanda Grech, Zhixian Sui, Hong Ying Siu, Miaobing Zheng, Margaret Allman-Farinelli, Anna Rangan
Diet quality indices have been shown to predict cardiovascular disease, cancer, Type 2 Diabetes, obesity and all-cause mortality. This study aimed to determine the socio-demographics of Australian adults with poor diet quality. Diet quality was assessed for participants of the 2011-2012 National Nutrition and Physical Activity Survey aged 18 years or above (n = 9435), with the validated 11-component Healthy Eating Index for Australians (HEIFA-2013), based on the 2013 Australian Dietary Guidelines. Differences in scores by demographics (ANOVA) and regression models for associations between the HEIFA-2013 score and demographic characteristics were conducted...
February 4, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28155612/the-influence-of-dietary-components-on-early-signs-of-atherosclerosis-in-apparently-healthy-young-adult-males-an-observational-study-of-615-subjects
#18
Girolamo Catapano Minotti, Francesca Cortese, Andrea Corsonello, Giovanni Guadalupi, Antonio Paolo D Arcangelo, Saverio Daniele Palumbo, Rita Naio, Ottovio De Clemente, Andrea Aurelio, Simona Carone, Tiziana Gelsumino, Vincenzo Gemignani, Elisabetta Bianchini, Mariangela Vigotti, Francesco Faita, Luciano Greco, Roberto Primerano, Raffaele Antonelli Incalzi, Marco Matteo Ciccone
BACKGROUND: the literature shows that a healthy diet, rich in fruits and vegetables, has positive effects on overall cardiovascular risk, protecting against atherosclerosis. DESIGN: a cross sectional study in a population of apparently healthy young-adult men with the aim of investigating dietary determinants of early atherosclerosis, assessed by measuring carotid intima-media thickness (cIMT) and flow-mediated dilation (FMD) of the brachial artery. METHODS: 615 males (mean age ± SD: 40...
February 1, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28150350/nutrient-intakes-and-compliance-with-nutrient-recommendations-in-children-aged-1-4-years-in-ireland
#19
J Walton, L Kehoe, B A McNulty, A P Nugent, A Flynn
BACKGROUND: The early childhood years represent a period of rapid growth and development characterised by unique requirements for energy and individual nutrients. METHODS: The present study uses data from the National Pre-School Nutrition Survey, a nationally representative sample of Irish children (1-4 years) (n = 500), aiming to estimate energy and nutrient intakes across age and compliance with recommendations (UK and European). A 4-day weighed food-record was used to collect dietary data and statistical modelling (National Cancer Institute method) was applied to estimate usual nutrient intakes...
February 2, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28142298/palm-oil-and-human-health-meeting-report-of-nfi-nutrition-foundation-of-italy-symposium
#20
Franca Marangoni, Claudio Galli, Andrea Ghiselli, Giovanni Lercker, Carlo La Vecchia, Claudio Maffeis, Carlo Agostoni, Donatella Ballardini, Ovidio Brignoli, Pompilio Faggiano, Rosalba Giacco, Claudio Macca, Paolo Magni, Giuseppe Marelli, Walter Marrocco, Vito Leonardo Miniello, Gian Francesco Mureddu, Nicoletta Pellegrini, Roberto Stella, Ersilia Troiano, Elvira Verduci, Roberto Volpe, Andrea Poli
The use of palm oil by the food industry is increasingly criticized, especially in Italy, for its purported negative effects on human health and environment. This paper summarizes the conclusions of a Symposium on this topic, gathered by the Nutrition Foundation of Italy, among experts representing a number of Italian Medical and Nutritional Scientific Societies. Toxicological and environmental issues were not considered. Participants agreed that: no evidence does exist on the specific health effects of palm oil consumption as compared to other saturated fatty acids-rich fats; the stereospecific distribution of saturated fatty acids in the triacylglycerol molecule of palm oil limits their absorption rate and metabolic effects; in agreement with International guidelines, saturated fatty acids intake should be kept <10% of total energy, within a balanced diet; within these limits, no effect of palm oil consumption on human health (and specifically on CVD or cancer risk) can be foreseen...
January 31, 2017: International Journal of Food Sciences and Nutrition
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