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Mohammad Ashkan Moslehi, Mohammad Hadi Imanieh, Ali Adib
Foreign body aspiration (FBA) is a common incidence in young children. Leeches are rarely reported as FBA at any age. This study describes a 15-year-old female who presented with hemoptysis, hematemesis, coughs, melena, and anemia seven months prior to admission. Chest X-ray showed a round hyperdensity in the right lower lobe. A chest computed tomography (CT) demonstrated an area of consolidation and surrounding ground glass opacities in the right lower lobe. Hematological investigations revealed anemia. Finally, bronchoscopy was performed and a 5 cm leech was found within the right B7-8 bronchus and removed by forceps and a Dormia basket...
2016: Case Reports in Pediatrics
Madathipat Unnikrishnan, Sidharth Viswanathan, K Balasubramaniam, C V Muraleedharan, Arthur Vijayan Lal, P V Mohanan, Meera Mohanty, Tirur Raman Kapilamoorthy
BACKGROUND & OBJECTIVES: Vascular illnesses are on the rise in India, due to increase in lifestyle diseases and demographic transition, requiring intervention to save life, organ or limbs using vascular prosthesis. The aim of this study was to develop indigenous large diameter vascular graft for treatment of patients with vascular pathologies. METHODS: The South India Textile Research Association, at Coimbatore, Tamil Nadu, India, developed seamless woven polyester (Polyethylene terephthalate) graft at its research wing...
June 2016: Indian Journal of Medical Research
Amy Irby-Shasanmi, Tamara G J Leech
OBJECTIVE: Surveys often ask respondents to assess discrimination in health care. Yet, patients' responses to one type of widely used measure of discrimination (single-item, personally mediated) tend to reveal prevalence rates lower than observational studies would suggest. This study examines the meaning behind respondents' closed-ended self-reports on this specific type of measure, paying special attention to the frameworks and references used within the medical setting. DESIGN: Twenty-nine respondents participated in this study...
October 14, 2016: Ethnicity & Health
J Rothenberger, W Petersen, H E Schaller, M Held
A universal protocol determining the number of leeches and their application time does not exist. The aim of this study, therefore, is to quantify perfusion dynamics in venous congested tissues after leech application to get more detailed information about changes due to leech-induced skin microcirculation and to evaluate the usability of the O2C device in terms of determining the appropriate number of leeches and the duration of therapy. Twelve patients with the need for leech therapy participated in the study...
October 12, 2016: Wound Repair and Regeneration
Tomozumi Takatani, Jun Shirakawa, Michael W Roe, Colin A Leech, Bernhard F Maier, Raghavendra G Mirmira, Rohit N Kulkarni
No abstract text is available yet for this article.
October 10, 2016: Scientific Reports
Paul Kavanagh, Catherine H Botting, Partha S Jana, Donal Leech, Florence Abram
Geobacter sulfurreducens is a dissimilatory metal-reducing bacterium capable of forming thick electron-conducting biofilms on solid electrodes. Here, we employ for the first time comparative proteomics to identify key physiological changes involved in G. sulfurreducens adaptation from fumarate-respiring planktonic cells to electron-conducting biofilms. Increased levels of proteins involved in outer membrane biogenesis, cell motility and secretion are expressed in biofilms. Of particular importance to the electron-conducting biofilms are proteins associated with secretion systems of Type I, II, V and Type IV pili...
October 10, 2016: Journal of Proteome Research
Kaveh Darabi-Darestani, Alireza Sari, Alimorad Sarafrazi
The present checklist contains 22 species belonging to 14 genera of six families of leeches known to date from Iran. Five species including Dina punctata punctata Johannson, 1927, Erpobdella monostriata (Lindenfeld & Pietruszynski, 1890), E. vilnensis (Liskiewicz, 1925), Trocheta haskonis Grosser, 2000 and Glossiphonia concolor (Apathty, 1888) are new records for the country.
September 22, 2016: Zootaxa
Behnam Salimi, Kazem Abdi
Leeches have been reported to harbor several important fish pathogens, including spring viremia of carp virus, infectious hematopoietic necrosis virus (IHNV), and viral hemorrhagic septicemia virus (VHSV), and also may contain blood protozoa. In the present study, leeches were collected from water bodies located in Kurdistan province, Iran. The specimens were tested for IHNV, VHSV, and infectious pancreatic necrosis virus (IPNV) using the PCR method. The results showed that two different species of leeches, Hemiclepsis marginata and Hirudo medicinalis, were infected by IPNV among the seven species studied...
December 2016: Journal of Aquatic Animal Health
Wei-Hui Liu, Yan Chen, Xue-Wei Bai, Hui-Min Yao, Xu-Guang Zhang, Xiu-Wen Yan, Ren Lai
The present study was designed to identify immunomodulatory components from the leech salivary gland of Haemadipsa sylvestris. The Sephadex G-50, Resource(TM) S column chromatography and reverse-phase high performance liquid chromatography (RP-HPLC) were used to isolate and purify the salivary gland extracts (SGE). Structural analysis of isolated compounds was based on Edman degradation and matrix assisted laser desorption ionization time-of-flight mass spectrometer (MALDI-TOF-MS). The cDNA encoding the precursor of the compound was cloned from the cDNA library of the salivary gland of H...
September 2016: Chinese Journal of Natural Medicines
A Dubois, M Arefi, M P Splitt, S Leech, S Natarajan, N Rajan
No abstract text is available yet for this article.
October 2016: Clinical and Experimental Dermatology
Jason E Pipkin, Eric A Bushong, Mark H Ellisman, William B Kristan
Microscale connectomics involves the large-scale acquisition of high-resolution serial electron micrographs from which neuronal arbors can be reconstructed and synapses can be detected. In addition to connectivity information, these data sets are also rich with structural information, including vesicle types, number of postsynaptic partners at a given presynaptic site, and spatial distribution of synaptic inputs and outputs. This study uses serial block-face scanning electron microscopy (EM) to collect two volumes of serial EM data from ganglia of the medicinal leech...
December 15, 2016: Journal of Comparative Neurology
Marcia Spear
Leech therapy is the ancient practice of bloodletting or bloodsucking and is considered one of the oldest medical practices known. Its use has spanned centuries and is still used in plastic surgery practices today when performing free flaps and replants. The purpose of this article is to discuss the history of this ancient therapy and to describe the leech and its present indications, complications, contraindications, and techniques.
July 2016: Plastic Surgical Nursing
Ricardo Pio Monti, Romy Lorenz, Rodrigo M Braga, Christoforos Anagnostopoulos, Robert Leech, Giovanni Montana
Two novel and exciting avenues of neuroscientific research involve the study of task-driven dynamic reconfigurations of functional connectivity networks and the study of functional connectivity in real-time. While the former is a well-established field within neuroscience and has received considerable attention in recent years, the latter remains in its infancy. To date, the vast majority of real-time fMRI studies have focused on a single brain region at a time. This is due in part to the many challenges faced when estimating dynamic functional connectivity networks in real-time...
September 7, 2016: Human Brain Mapping
Anca Doloc-Mihu, Ronald L Calabrese
The underlying mechanisms that support robustness in neuronal networks are as yet unknown. However, recent studies provide evidence that neuronal networks are robust to natural variations, modulation, and environmental perturbations of parameters, such as maximal conductances of intrinsic membrane and synaptic currents. Here we sought a method for assessing robustness, which might easily be applied to large brute-force databases of model instances. Starting with groups of instances with appropriate activity (e...
July 2016: ENeuro
Shuaishuai Li, Long Cheng, Dengkun An, Shuliang Song, Hao Liang, Fulong Chu, Aiguo Ji
AIM: Atherosclerosis is a kind of chronic inflammatory disease. A crucial pathology change of atherosclerosis is the migration of activated VSMCs to the intima where they interact with leukocytes by expressing adhesion molecules, including intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). Moreover, monocyte chemoattractant protein-1 (MCP-1) expressed by VSMCs plays an important role in recruiting monocytes and macrophages. Leech (Whitmania pigra Whitman) is a traditional Chinese medicine to treat cardiovascular diseases including atherosclerosis, however previous research has rarely reported the molecular mechanism for its curative effect...
September 2, 2016: Journal of Atherosclerosis and Thrombosis
Ronald L Calabrese, Brian J Norris, Angela Wenning
The neurogenic heartbeat of certain invertebrates has long been studied both as a way of understanding how automatic functions are regulated and for how neuronal networks generate the inherent rhythmic activity that controls and coordinates this vital function. This review focuses on the heartbeat of decapod crustaceans and hirudinid leeches, which remain important experimental systems for the exploration of central pattern generator networks, their properties, network and cellular mechanisms, modulation, and how animal-to-animal variation in neuronal and network properties are managed to produce functional output...
August 30, 2016: Current Opinion in Neurobiology
Daniel Kueh, William H Barnett, Gennady S Cymbalyuk, Ronald L Calabrese
The dynamics of different ionic currents shape the bursting activity of neurons and networks that control motor output. Despite being ubiquitous in all animal cells, the contribution of the Na(+)/K(+) pump current to such bursting activity has not been well studied. We used monensin, a Na(+)/H(+) antiporter, to examine the role of the pump on the bursting activity of oscillator heart interneurons in leeches. When we stimulated the pump with monensin, the period of these neurons decreased significantly, an effect that was prevented or reversed when the h-current was blocked by Cs(+)...
2016: ELife
Adriana De-La-Rosa Tovar, Prashant K Mishra, Francisco F De-Miguel
We studied how a neuronal circuit composed of two neuron types connected by chemical and electrical synapses maintains constant its integrative capacities as neurons grow. For this we combined electrophysiological experiments with mathematical modeling in pairs of electrically-coupled Retzius neurons from postnatal to adult leeches. The electrically-coupled dendrites of both Retzius neurons receive a common chemical input, which produces excitatory postsynaptic potentials (EPSPs) with varying amplitudes. Each EPSP spreads to the soma, but also crosses the electrical synapse to arrive at the soma of the coupled neuron...
2016: Frontiers in Cellular Neuroscience
Rebecca M Leech, Katherine M Livingstone, Anthony Worsley, Anna Timperio, Sarah A McNaughton
BACKGROUND: Skipping breakfast is associated with poorer diet quality among adults, but evidence of associations for other eating patterns [e.g., eating occasion (EO), meal, or snack frequency] is equivocal. An understanding of how eating patterns are associated with diet quality is needed to inform population-level dietary recommendations. OBJECTIVE: We aimed in this cross-sectional study to determine the relation between frequency of meals, snacks, and all EOs with nutrient intakes and diet quality in a representative sample of Australian adults...
October 2016: Journal of Nutrition
Lincoln Lima Corrêa, Marcos Sidney Brito Oliveira, Marcos Tavares-Dias, Paulo Sérgio Ceccarelli
Among Kinetoplastida, the Trypanosoma is the genus with the highest occurrence infecting populations of marine fish and freshwater in the world, with high levels of prevalence, causing influences fish health and consequent economic losses, mainly for fish populations in situation stress. This study investigated infections of Hypostomus spp. by Trypanosoma spp. and leeches, as well as blood parameters of this host in the network of tributaries of the Tapajós River in the state of Pará, in the eastern Amazon region in Brazil...
July 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
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