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Tolga Çakmak, İbrahim Çaltekin, Emre Gökçen, Atakan Savrun, Erdoğan Yaşar
Kounis Syndrome is the development of acute coronary syndrome (ACS) because of allergic reactions; allergens, such as foods, insect venom, iodine contrast agent or drugs can cause this syndrome. Hirudotherapy (leech therapy) is increasingly used as a useful therapeutic option in a variety of medical and surgical procedures, and potential complications related to this therapy include Aeromonas species infections, bleeding, anemia and allergic reactions. Here, we present a patient diagnosed as Type 1 Kounis Syndrome after using hirudotherapy for her knee aches...
June 2018: Turkish Journal of Emergency Medicine
Melody J Gavel, R Timothy Patterson, Nawaf A Nasser, Jennifer M Galloway, Bruce W Hanna, Peter A Cott, Helen M Roe, Hendrik Falck
Frame Lake, located within the city of Yellowknife, Northwest Territories, Canada, has been identified as requiring significant remediation due to its steadily declining water quality and inability to support fish by the 1970s. Former gold mining operations and urbanization around the lake have been suspected as probable causes for the decline in water quality. While these land-use activities are well documented, little information is available regarding their impact on the lake itself. For this reason, Arcellinida, a group of shelled protozoans known to be reliable bioindicators of land-use change, were used to develop a hydroecological history of the lake...
2018: PeerJ
Wayne Paes, Adam Dowle, Jamie Coldwell, Andrew Leech, Tim Ganderton, Andrzej Brzozowski
Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterial pathogen, and the leading cause of infectious blindness worldwide. We have recently shown that immunization with the highly conserved antigenic passenger domain of recombinant Ct polymorphic membrane protein D (rPmpD) is protective in the mouse model of Ct genital tract infection, and previously, that ocular anti-rPmpD antibodies are elicited following vaccination. However, the mechanisms governing the assembly and structure-function relationship of PmpD are unknown...
2018: PloS One
Hideshi Naka, Seiichi Kubota, Fumitaka Kuchiki, Hiroshi Shibasaki, Masanobu Yamamoto, Yasuyoshi Soejima, Yutaka Arita, Tetsu Ando
Female sex pheromone of a clearwing moth Nokona feralis (Leech) (Lepidoptera: Sesiidae), a pest of kiwifruit, was identified to be a 7:3 mixture of (3E,13Z)-3,13-octadecadienyl acetate (E3,Z13-18:OAc) and (3E,13Z)-3,13-octadecadien-1-ol (E3,Z13-18:OH) by GC-EAD and GC/MS analyses. Males were attracted to wide-range mixtures of E3,Z13-18:OAc and E3,Z13-18:OH, and a 7:3 mixture of those two compounds strongly attracted the males in the field.
June 18, 2018: Bioscience, Biotechnology, and Biochemistry
Kristan A Leech, Ryan T Roemmich
People can acquire new walking patterns in many different ways. For example, we can change our gait voluntarily in response to instruction or adapt by sensing our movement errors. Here we investigated how acquisition of a new walking pattern through simultaneous voluntary correction and adaptive learning affected the resulting motor memory of the learned pattern. We studied adaptation to split-belt treadmill walking with and without visual feedback of stepping patterns. As expected, visual feedback enabled faster acquisition of the new walking pattern...
June 14, 2018: Journal of Experimental Biology
Mostafa Karimaei, Mohammad Maroosi, Mansour Baziar, Hamed Biglari, Hooshmand Sharafi, Nezam Mirzaei, Amir Hossein Mahvi
The aquatic ecosystems are continuously endangered due to variety of hazardous chemicals containing different toxic agents which can be emitted from anthropogenic sources. Besides the increasing of human population, various kinds of contaminants enter into the surface water resources. The aim of the present study was to investigate the abundance and diversity of macro invertebrates in two permanent streams located in the northern part of Tehran. The biological integrity of the streams was determined by manual sampling approach at five points...
August 2018: Data in Brief
Sharon L Brennan-Olsen, Svetlana Solovieva, Eira Viikari-Juntura, Ilana N Ackerman, Steven J Bowe, Paul Kowal, Nirmala Naidoo, Somnath Chatterji, Anita E Wluka, Michelle T Leech, Richard S Page, Kerrie M Sanders, Fernando Gomez, Gustavo Duque, Darci Green, Mohammadreza Mohebbi
BACKGROUND: In higher income countries, work-related squatting and heavy lifting have been associated with increased arthritis risk. Here, we address the paucity of data regarding associations between arthritis and work-related physical stressors in lower- and middle-income countries. METHODS: Data were extracted from the Study on global AGEing and adult health (SAGE) Wave 1 (2007-10) for adults (aged ≥50 years) from Ghana, India, Russia and South Africa for whom detailed occupation data was available (n = 21,389; 49...
June 8, 2018: BMC Public Health
Ida Baerholm Schnell, Kristine Bohmann, Sebastian E Schultze, Stine R Richter, Dáithí C Murray, Mikkel-Holger S Sinding, David Bass, John E Cadle, Mason J Campbell, Rainer Dolch, David P Edwards, Thomas N E Gray, Teis Hansen, Anh Nguyen Quang Hoa, Christina Lehmkuhl Noer, Sigrid Heise-Pavlov, Adam F Sander Pedersen, Juliot Carl Ramamonjisoa, Mark E Siddall, Andrew Tilker, Carl Traeholt, Nicholas Wilkinson, Paul Woodcock, Douglas W Yu, Mads Frost Bertelsen, Michael Bunce, M Thomas P Gilbert
The use of environmental DNA (eDNA) has become an applicable non-invasive tool with which to obtain information about biodiversity. A sub-discipline of eDNA is iDNA (invertebrate-derived DNA), where genetic material ingested by invertebrates is used to characterise the biodiversity of the species that served as hosts. While promising, these techniques are still in their infancy, as they have only been explored on limited numbers of samples from only a single or a few different locations. In this study, we investigate the suitability of iDNA extracted from more than 3,000 haematophagous terrestrial leeches as a tool for detecting a wide range of terrestrial vertebrates across five different geographical regions on three different continents...
June 7, 2018: Molecular Ecology Resources
Rebecca M Leech, Anna Timperio, Anthony Worsley, Sarah A McNaughton
PURPOSE: Eating patterns have been linked to obesity, an established risk factor for hypertension; however, their contribution to hypertension is poorly understood. This study aimed to examine associations of frequency of meals, snacks and all eating occasions (EO), and temporal eating patterns, with blood pressure (BP) and hypertension. METHODS: Dietary data collected via two 24-h recalls during the 2011-2012 Australian National Nutrition and Physical Activity Survey (n = 4482 adults, ≥ 19 years) were analysed...
June 6, 2018: European Journal of Nutrition
Kate E Plummer, Stuart Bearhop, David I Leech, Dan E Chamberlain, Jonathan D Blount
Throughout the Western World, huge numbers of people regularly supply food for wild birds. However, evidence of negative impacts of winter feeding on future reproduction has highlighted a need to improve understanding of the underlying mechanisms shaping avian responses to supplementary food. Here, we test the possibility that carry-over effects are mediated via their impact on the phenotypes of breeding birds, either by influencing the phenotypic structure of populations through changes in winter survival and/or by more direct effects on the condition of breeding birds...
May 2018: Ecology and Evolution
Yanxian Lin, Weiming Song
Objective: To summarize the monitoring methods and preventions of the disorder of blood supplying of expanded flaps, so as to provide some references for improving the survival of expanded flaps. Methods: The domestic and abroad related literature about the disorder of blood supplying of expanded flaps was reviewed and analyzed. Results: Handheld Doppler, digital subtraction angiography, computer tomographic angiography, magnetic resonance angiography, and fluorescein angiography can be used as reliable preoperative imaging methods in designing expanded flaps with rich blood supply...
January 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
Erik D Fagerholm, Martin Dinov, Thomas Knöpfel, Robert Leech
Local perturbations within complex dynamical systems can trigger cascade-like events that spread across significant portions of the system. Cascades of this type have been observed across a broad range of scales in the brain. Studies of these cascades, known as neuronal avalanches, usually report the statistics of large numbers of avalanches, without probing the characteristic patterns produced by the avalanches themselves. This is partly due to limitations in the extent or spatiotemporal resolution of commonly used neuroimaging techniques...
2018: PloS One
Heather A Nelson, Colin A Leech, Richard F Kopp, Michael W Roe
Store-operated calcium entry (SOCE), a fundamentally important homeostatic and Ca2+ signaling pathway in many types of cells, is activated by the direct interaction of stromal interaction molecule 1 (STIM1), an endoplasmic reticulum (ER) Ca2+ -binding protein, with Ca2+ -selective Orai1 channels localized in the plasma membrane. While much is known about the regulation of SOCE by STIM1, the role of stromal interaction molecule 2 (STIM2) in SOCE remains incompletely understood. Here, using clustered regularly interspaced short palindromic repeats -CRISPR associated protein 9 (CRISPR-Cas9) genomic editing and molecular imaging, we investigated the function of STIM2 in NIH 3T3 fibroblast and αT3 cell SOCE...
May 19, 2018: International Journal of Molecular Sciences
Abdullah İnci, Mehmet Doğanay, Aykut Özdarendeli, Önder Düzlü, Alparslan Yıldırım
Zoonotic infections are globally important diseases and lead to huge economic losses in both low- and middle-income and high-income countries. Global warming, environmental and ecological changes, illegal movement of animals and humans, regional civil wars, and poverty are predisposing factors for the emergence of zoonotic infections and their distribution worldwide; they are also a big threat for the future. In addition, environmental pollution and antimicrobial resistance are immense serious threats and dangers to prevent and control zoonotic infections...
March 2018: Türkiye Parazitolojii Dergisi
Michael Tessler, Danielle de Carle, Madeleine L Voiklis, Olivia A Gresham, Johannes Neumann, Stanisław Cios, Mark E Siddall
Annelids possessing a posterior sucker and a fixed number of somites - most famously leeches (Hirudinida), but also crayfish worms (Branchiobdellida) and salmonid parasites (Acanthobdellida) - form a clade; however, determining the relationships between these orders has proven challenging. Here, we compile the largest molecular phylogenetic dataset yet analysed for these groups, including new sequences for key taxa. We find robust model-based support for a clade formed by Hirudinida and Acanthobdellida, contrasting the largest prior studies...
May 17, 2018: Molecular Phylogenetics and Evolution
Ruslan F Aminov, Aleksandr K Frolov
The aim of the study was to determine the immunostimulatory effect of antigens from saline extract of the medicinal leech on the morphometric parameters of the body and major immunogenic organs of rats. Wild-type female rats were administered medicinal leech saline extract antigens intraperitoneally two weeks before and two weeks after mating (in total four injections). The offspring were examined, as were the mothers after feeding the offspring, at 1, 15, 30, 60 days after birth. The morphometric parameters of the animals were recorded...
2018: Annals of Parasitology
Emily L Kasl, William F Font, Charles D Criscione
The evolutionary causes and consequences of changes in complex life cycles are of central importance in parasitology. However, data remain limited because in part, knowledge on phylogenetic relationships among species that differ in life cycle patterns remains scarce. We present a molecular phylogeny of the trematode genus Alloglossidium, which contains several species that display precocious (a.k.a., progenetic) life cycles (i.e., maturation in what is typically regarded as an intermediate host). The molecular phylogeny contrasts with previous morphological and life-history based phylogenetic hypotheses...
September 2018: Molecular Phylogenetics and Evolution
Bradley Leech, Janet Schloss, Amie Steel
BACKGROUND: This study aims to explore the conditions complementary and integrative medicine (CIM) practitioners associate with increased intestinal permeability (IP) and the methods they employ to assess IP. METHODS: A cross-sectional survey of naturopaths, nutritionists and Western herbal medicine practitioners was undertaken (n = 227) through the Practitioner Research and Collaboration Initiative (PRACI) network. RESULTS: CIM practitioners (n = 36, response rate 15...
May 2018: Complementary Therapies in Clinical Practice
Haixia Wang, Jing Zhang, Liyan Chen
BACKGROUND: It is controversial on whether medical leech therapy is effective in improving pain and functional outcome in patients with knee osteoarthritis (OA). Therefore, we perform a meta-analysis from randomized controlled trials (RCTs) to evaluate the efficacy and safety of medical leech therapy in patients with knee OA. MATERIALS AND METHODS: The PubMed, EMBASE, ScienceDirect, and Cochrane Library databases were systematically searched for literature up to January 2018...
June 2018: International Journal of Surgery
Navneet Singh, Rahul Ranjan
The genus Orybina Snellen, 1895, a member of tribe Pyralini of the subfamily Pyralinae and family Pyralidae, was established as the objective replacement name for Oryba Walker, 1863. The original genus Oryba was established for its type species Oryba flaviplaga Walker, 1863 (by monotypy) from North Hindostan [North India]. Recently, the genus is reviewed by Qi et al. (2017) with inclusion of eight species and one subspecies in the World: Orybina kobesi Roesler, 1984, Orybina plangonalis (Walker, 1859), Orybina regalis (Leech, 1889), Orybina bellatulla Qi Li, 2017, Orybina puerensis Qi Li, 2017, Orybina hoenei Caradja, 1935, Orybina flaviplaga (Walker, 1863), Orybina imperatrix Caradja, 1925 and Orybina flaviplaga kiangsualis Caradja, 1925...
March 11, 2018: Zootaxa
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