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https://www.readbyqxmd.com/read/28089556/larval-stages-of-neoplagioporus-elongatus-goto-and-ozaki-1930-opecoelidae-plagioporinae-with-notes-on-potential-second-intermediate-hosts
#1
Ayaka Yano, Misako Urabe
The morphology of sporocysts and cercariae of Neoplagioporus elongatus (Goto and Ozaki, 1930) is described for the first time. A cotylomicrocercous cercaria obtained from the sorbeoconch snail Semisulcospira nakasekoae was confirmed to be the cercaria of N. elongatus, based on the degree of sequence identity of the COI gene to that of adult worms. Freshwater annelids (oligochaetes and leeches) and some aquatic insects (odonates) were demonstrated experimentally to be potential second intermediate hosts.
January 9, 2017: Parasitology International
https://www.readbyqxmd.com/read/28070637/human-recombinant-rnaset2-induced-inflammatory-response-and-connective-tissue-remodeling-in-the-medicinal-leech
#2
Nicolò Baranzini, Edoardo Pedrini, Rossana Girardello, Gianluca Tettamanti, Magda de Eguileor, Roberto Taramelli, Francesco Acquati, Annalisa Grimaldi
In recent years, several studies have demonstrated that the RNASET2 gene is involved in the control of tumorigenicity in ovarian cancer cells. Furthermore, a role in establishing a functional cross-talk between cancer cells and the surrounding tumor microenvironment has been unveiled for this gene, based on its ability to act as an inducer of the innate immune response. Although several studies have reported on the molecular features of RNASET2, the details on the mechanisms by which this evolutionarily conserved ribonuclease regulates the immune system are still poorly defined...
January 9, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28061795/temporal-eating-patterns-a-latent-class-analysis-approach
#3
Rebecca M Leech, Anthony Worsley, Anna Timperio, Sarah A McNaughton
BACKGROUND: There is some evidence that large energy intakes towards the end of the day are associated with adverse health outcomes, however, studies of temporal eating patterns across the day are rare. This study examines the temporal eating patterns of Australian adults using latent class analysis (LCA), as a novel approach. METHODS: Dietary data (n = 2402 men and n = 2840 women, ≥19 years) from two 24-h recalls collected during the 2011-12 Australian National Nutrition and Physical Activity Survey were analyzed...
January 7, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28052398/multi-state-multi-stage-modeling-of-nest-success-suggests-interaction-between-weather-and-land-use
#4
Mark W Miller, David I Leech, James W Pearce-Higgins, Robert A Robinson
Many factors may affect daily nest survival. We present a novel multi-state, multi-stage model to estimate daily survival for each nest stage, daily hatching probability and probability that a failed nest died during a specific stage when stage of failure is unknown. The model does not require that hatching date be known. We used data from a large citizen science dataset to demonstrate the application of this approach, exploring the impact of laying dates, weather conditions, conserved soil moisture, soil carbon, habitat type and urbanization on failure rates of common blackbird (Turdus merula) nests...
January 2017: Ecology
https://www.readbyqxmd.com/read/28039528/drivers-of-symbiont-diversity-in-freshwater-snails-a-comparative-analysis-of-resource-availability-community-heterogeneity-and-colonization-opportunities
#5
Keegan McCaffrey, Pieter T J Johnson
Decades of community ecology research have highlighted the importance of resource availability, habitat heterogeneity, and colonization opportunities in driving biodiversity. Less clear, however, is whether a similar suite of factors explains the diversity of symbionts. Here, we used a hierarchical dataset involving 12,712 freshwater snail hosts representing five species to test the relative importance of potential factors in driving symbiont richness. Specifically, we used model selection to assess the explanatory power of variables related to host species identity, resource availability (average body size, host density), ecological heterogeneity (richness of hosts and other taxa), and colonization opportunities (wetland size and amount of neighboring wetland area) on symbiont richness in 146 snail host populations in California, USA...
December 30, 2016: Oecologia
https://www.readbyqxmd.com/read/28003364/stromal-interaction-molecule-1-stim1-regulates-atp-sensitive-potassium-katp-and-store-operated-ca2-channels-in-min6-%C3%AE-cells
#6
Colin A Leech, Richard F Kopp, Heather A Nelson, Jyotirmoy Nandi, Michael W Roe
Stromal interaction molecule 1 (STIM1) regulates store-operated Ca(2+) entry (SOCE) and other ion channels, either as an endoplasmic reticulum (ER) Ca(2+) sensing protein or when present in the plasma membrane. However, the role of STIM1 in insulin-secreting β-cells is unresolved. We report that lowering expression of STIM1, the gene that encodes STIM1, in insulin-secreting MIN6 β-cells with RNA interference inhibits SOCE and ATP-sensitive K(+) (KATP) channel activation. The effects of STIM1 knockdown were reversed by transduction of MIN6 cells with an adenovirus gene shuttle vector that expressed human STIM1 Immunoprecipitation studies revealed that STIM1 binds to nucleotide binding fold-1 (NBF1) of the sulfonylurea receptor 1 (SUR1) subunit of the KATP channel...
December 21, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27995665/changes-in-sleep-duration-and-recreational-screen-time-among-canadians-1998-2010
#7
Judith A Leech
It is commonly claimed that sleep duration has declined in recent years - over a period coinciding with a marked increase in personal electronics and communications use. The aim of this study was to assess change in sleep duration among Canadians from 1998 to 2010, and examine any associations with non-work-related screen time. The analysis uses population-representative data from Statistics Canada's General Social Survey cycles of 1998 and 2010; the respective samples numbered 10 749 and 15 390 individuals...
December 20, 2016: Journal of Sleep Research
https://www.readbyqxmd.com/read/27988697/on-the-taxonomy-of-the-genus-i-acronicta-i-lepidoptera-noctuidae-iii-i-acronicta-i-lutea-species-group
#8
Anton V Volynkin, Dieter Stüning, Alexej Yu Matov
The present paper is the third in a series of articles on the genus Acronicta Ochsenheimer, 1816 (Volynkin et al. 2015; Volynkin 2015). Here we focus on the taxonomy of the Acronicta lutea species group, designating the lectotype of Acronicta lutea (Bremer & Grey, 1852), revising synonym status of Acronycta metaxantha funesta Draudt, 1950 and Pharetra leucoptera Butler, 1881, transferring Acronicta nigricans (Leech, 1900) to the subgenus Viminia Chapman, 1890 and introducing the new synonymy A. nigricans = Acronicta regifica Draudt, 1937 syn...
November 17, 2016: Zootaxa
https://www.readbyqxmd.com/read/27987051/expression-patterns-indicate-that-bmp2-4-and-chordin-not-bmp5-8-and-gremlin-mediate-dorsal-ventral-patterning-in-the-mollusk-crassostrea-gigas
#9
Sujian Tan, Pin Huan, Baozhong Liu
Though several bilaterian animals use a conserved BMP2/4-Chordin antagonism to pattern the dorsal-ventral (DV) axis, the only lophotrochozoan species in which early DV patterning has been studied to date, the leech Helobdella robusta, appears to employ BMP5-8 and Gremlin. These findings call into question the conservation of a common DV patterning mechanism among bilaterian animals. To explore whether the unusual DV patterning mechanism in H. robusta is also used in other lophotrochozoan species, we investigated the expression of orthologous genes in the early embryo of a bivalve mollusk, Crassostrea gigas...
December 16, 2016: Development Genes and Evolution
https://www.readbyqxmd.com/read/27942855/functional-neuroimaging-of-visuo-vestibular-interaction
#10
R E Roberts, H Ahmad, Q Arshad, M Patel, D Dima, R Leech, B M Seemungal, D J Sharp, A M Bronstein
The brain combines visual, vestibular and proprioceptive information to distinguish between self- and world motion. Often these signals are complementary and indicate that the individual is moving or stationary with respect to the surroundings. However, conflicting visual motion and vestibular cues can lead to ambiguous or false sensations of motion. In this study, we used functional magnetic resonance imaging to explore human brain activation when visual and vestibular cues were either complementary or in conflict...
December 10, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27942471/mixed-vascular-nevus-syndrome-a-report-of-four-new-cases-and-a-literature-review
#11
Martino Ruggieri, Agata Polizzi, Serena Strano, Carmelo Schepis, Massimiliano Morano, Giuseppe Belfiore, Stefano Palmucci, Pietro Valerio Foti, Concetta Pirrone, Vito Sofia, Emanuele David, Vincenzo Salpietro, Kshitij Mankad, Pietro Milone
BACKGROUND: Mixed vascular nevus (or nevus vascularis mixtus) represents an admixture of cutaneous vascular malformations of the telangiectatic type and angiospastic spots of nevus anemicus. It can occur as an purely cutaneous trait or as a hallmark of a neurocutaneous phenotype (mixed vascular nevus syndrome) characterised by the combination of: (I) paired vascular (telangiectatic and anemic) twin nevi and brain abnormalities of the Dyke-Davidoff-Masson type (i.e., crossed cerebral/cerebellar hemiatrophy with hypoplasia of the ipsilateral cerebral vessels and homolateral hypertrophy of the skull and sinuses (hyperpneumatisation) with contralateral hemispheric hypertrophy); or (II) paired vascular twin nevi and brain malformations of the Dyke-Davidoff-Masson type in association with systemic abnormalities consisting in facial asymmetry, skeletal anomalies (i...
October 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/27914138/therapeutic-response-for-functional-abdominal-pain-in-children-with-occult-constipation-laxatives-versus-prokinetic-drugs
#12
Eun Kyo Ha, Homin Jang, Su Jin Jeong
The relationship between functional abdominal pain (FAP) and occult constipation (OC) in children who did not meet the Rome III criteria for constipation has rarely been reported. This study aimed to estimate the prevalence of OC in patients with FAP and to compare the effectiveness of prokinetic drugs and laxatives for FAP and OC. Pediatric outpatients (n = 212; aged 4-15 years) who satisfied the Rome III criteria for childhood FAP were divided into 2 groups based on Leech scores: group 1 < 8; group 2 ≥ 8...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27888690/exploring-socioeconomic-differences-in-syntactic-development-through-the-lens-of-real-time-processing
#13
Yi Ting Huang, Kathryn Leech, Meredith L Rowe
Differences in caregiver input across socioeconomic status (SES) predict syntactic development, but the mechanisms are not well understood. Input effects may reflect the exposure needed to acquire syntactic representations during learning (e.g., does the child have the relevant structures for passive sentences?) or access this knowledge during communication (e.g., can she use the past participle to infer the meaning of passives?). Using an eye-tracking and act-out paradigm, the current study distinguishes these mechanisms by comparing the interpretation of actives and passives in 3- to 7-year-olds (n=129) from varying SES backgrounds...
February 2017: Cognition
https://www.readbyqxmd.com/read/27886606/a-symmetric-supercapacitor-biofuel-cell-hybrid-device-based-on-enzyme-modified-nanoporous-gold-an-autonomous-pulse-generator
#14
Xinxin Xiao, Peter Ó Conghaile, Dónal Leech, Roland Ludwig, Edmond Magner
The integration of supercapacitors with enzymatic biofuel cells (BFCs) can be used to prepare hybrid devices in order to harvest significantly higher power output. In this study, a supercapacitor/biofuel cell hybrid device was prepared by the immobilisation of redox enzymes with electrodeposited poly(3,4-ethylenedioxythiophene) (PEDOT) and the redox polymer [Os(2,2'-bipyridine)2(polyvinylimidazole)10Cl](+/2+)(Os(bpy)2PVI) on dealloyed nanoporous gold. The thickness of the deposition layer can be easily controlled by tuning the deposition conditions...
April 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27884974/from-leeches-to-personalized-medicine-evolving-concepts-in-the-management-of-polycythemia-vera
#15
REVIEW
Alessandro M Vannucchi
Polycythemia vera is a clonal disorder of hematopoietic stem/progenitor cells. It manifests as an expansion of red cell mass. It is the most common chronic myeloproliferative neoplasm. In virtually all cases, it is characterized by a V617F point mutation in JAK2 exon 14 or less common mutations in exon 12. The landmark discovery of the autonomously activated JAK/STAT signaling pathway paved the way for the clinical development of the first target drug, the JAK1 and JAK2 inhibitor ruxolitinib. This is now approved for patients with resistance or intolerance to hydroxyurea...
January 2017: Haematologica
https://www.readbyqxmd.com/read/27852177/examination-of-the-shoulder-joint
#16
Michelle T Leech, Stephen T Hall
No abstract text is available yet for this article.
November 21, 2016: Medical Journal of Australia
https://www.readbyqxmd.com/read/27829115/walking-the-walk
#17
Ana Leech
A Houston palliative care and hospice physician shares her family's experience caring for her father, who had a terminal illness, in this special four-part series originally published on the Texas Medical Association's MeAndMyDoctor blog.
November 1, 2016: Texas Medicine
https://www.readbyqxmd.com/read/27828766/prevalence-abundance-and-intensity-of-implanted-spermatophores-in-the-leech-haementeria-officinalis-glossiphoniidae-hirudinida-from-guanajuato-mexico
#18
Ricardo Salas-Montiel, Anna Phillips, Samantha Contreras-Mirà  N, Alejandro Francisco Oceguera-Figueroa
Fertilization through hypodermic implantation of spermatophores has been recorded in at least 4 groups of leeches: Glossiphoniidae, Piscicolidae, Ozobranchidae and Erpobdelliformes. In Piscicola respirans (Piscicolidae), vector tissue responsible for sperm transfer from a specialized region of the body to the ovaries has led to the non-random attachment of spermatophores on the body surface of the recipient leech. It has been suggested that in glossiphoniid leeches, spermatophores are implanted in any part of the body surface of the recipient leech without a clear pattern or preference for region...
November 9, 2016: Journal of Parasitology
https://www.readbyqxmd.com/read/27825524/paper-based-microfluidic-biofuel-cell-operating-under-glucose-concentrations-within-physiological-range
#19
Maria José González-Guerrero, F Javier Del Campo, Juan Pablo Esquivel, Dónal Leech, Neus Sabaté
This work addresses the development of a compact paper-based enzymatic microfluidic glucose/O2 fuel cell that can operate using a very limited sample volume (≈35µl) and explores the energy generated by glucose at concentrations typically found in blood samples at physiological conditions (pH 7.4). Carbon paper electrodes combined with a paper sample absorption substrate all contained within a plastic microfluidic casing are used to construct the paper-based fuel cell. The anode catalysts consist of glucose dehydrogenase and [Os(4,4'-dimethoxy-2,2'-bipyridine)2(poly-vinylimidazole)10Cl](+) as mediator, while the cathode catalysts were bilirubin oxidase and [Os(2,2'-bipyridine)2(poly-vinylimidazole)10Cl](+) as mediator...
April 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27818330/alive-in-the-airways-live-endobronchial-foreign-bodies
#20
REVIEW
Syed Rizwan Ali, Atul C Mehta
Aspiration of a foreign body into the lower airways is a common occurrence and can cause significant morbidity and mortality in humans. Most foreign bodies of the tracheobronchial tree are inanimate. However, medical literature includes reports of live foreign bodies in the airways. Fish, leeches and roundworms are the most common live foreign bodies of the lower airways. Fishermen are more prone to experience a live-fish aspiration while substandard conditions may expose individuals to leech and roundworm infestations...
November 3, 2016: Chest
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