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https://www.readbyqxmd.com/read/28242584/impact-of-stent-overlapping-on-long-term-clinical-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction-insights-from-the-5-year-follow-up-of-the-examination-trial
#1
Luis Ortega-Paz, Salvatore Brugaletta, Giuseppe Giacchi, Kohki Ishida, Angel Cequier, Andrés Iñiguez, Antonio Serra, Pilar Jiménez-Quevedo, Vicente Mainar, Gianluca Campo, Maurizio Tespili, Peter den Heijer, Marco Valgimigli, Patrick W Serruys, Manel Sabaté
AIMS: To compare long-term outcomes of STEMI patients treated with overlap vs. no-overlap stents. METHODS AND RESULTS: We analyzed the 1 and 5-year clinical outcomes of 1498 STEMI patients according to overlap stent implantation. The primary endpoint was a patient-oriented composite endpoint (PoCE) of all-cause death, myocardial infarction, and repeated revascularization. Stent thrombosis data was also analyzed. Four hundred four (27.0%) patients were treated with overlapping stents, whereas the remaining 1094 (73...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28236456/outcomes-after-percutaneous-coronary-intervention-of-acute-coronary-syndrome-complicated-with-cardiopulmonary-arrest-from-a-japanese-multicenter-registry
#2
Yohei Numasawa, Mitsuaki Sawano, Hiroaki Miyata, Ikuko Ueda, Shigetaka Noma, Masahiro Suzuki, Toshiki Kuno, Masaki Kodaira, Yuichiro Maekawa, Keiichi Fukuda, Shun Kohsaka
Details on the characteristics and outcomes in patients with acute coronary syndrome (ACS) complicated with cardiopulmonary arrest (CPA) have been limited. We evaluated inhospital outcomes after percutaneous coronary intervention in these patients. From 2008 to 2014, 5,943 patients with ACS including 2,973 patients with ST-elevation myocardial infarction (STEMI) and 2,970 patients with non-STEMI or unstable angina (NSTE-ACS) were registered. In total, 264 patients experienced CPA within 24 hours of admission...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28179617/relationship-between-serum-25-hydroxyvitamin-d-levels-and-the-syntax-score-in-patients-with-acute-coronary-syndrome
#3
Ahmet Oğuz Baktır, Yasemin Doğan, Bahadır Şarlı, Ömer Şahin, Erkan Demirci, Mahmut Akpek, Eyüp Özkan, Hüseyin Arınç, Hayrettin Sağlam
OBJECTIVE: The extent of severity and complexity of coronary artery disease (CAD) in patients presenting with ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) and possible correlations between serum 25-hydroxyvitamin D (25(OH)D) have not yet been adequately studied. We evaluated the relationship between 25(OH)D levels and the burden of CAD as assessed by the SYNTAX score (SXscore) in patients with acute coronary syndrome (ACS) including STEMI and NSTEMI. METHODS: After exclusion, a total of 113 patients who were admitted to our hospital due to ACS and who were referred for undergoing coronary angiography were prospectively included...
February 1, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27912733/the-effect-of-percutaneous-coronary-intervention-on-habitual-physical-activity-in-older-patients
#4
Sarah J Charman, Vincent T van Hees, Louise Quinn, Joseph R Dunford, Bilal Bawamia, Murugapathy Veerasamy, Michael I Trenell, Djordje G Jakovljevic, Vijay Kunadian
BACKGROUND: Given the ongoing burden of cardiovascular disease and an ageing population, physical activity in patients with coronary artery disease needs to be emphasized. This study assessed whether sedentary behaviour and physical activity levels differed among older patients (≥75 years) following percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) consisting of ST-segment elevation myocardial infarction (STEMI) and non STEMI (NSTEMI) versus an elective admission control group of stable angina patients...
December 3, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27899428/pronounced-increase-in-risk-of-acute-st-segment-elevation-myocardial-infarction-in-younger-smokers
#5
Amelia Lloyd, Lloyd Steele, James Fotheringham, Javaid Iqbal, Ayyaz Sultan, M Dawn Teare, Ever D Grech
OBJECTIVES: Previous studies have shown that smokers presented with ST-segment elevation myocardial infarction (STEMI) a decade earlier than non-smokers. However, no account has been made for population smoking trends, an important deficit addressed by this study. METHODS: The combination of admission data on patients with acute STEMI undergoing percutaneous coronary intervention and demographic data supplied by the Office for National Statistics for the South Yorkshire population between 2009-2012 were analysed to generate incidence rates and rate ratios (RR) to quantify the relative risk of STEMI from smoking, overall and by age group...
November 29, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27858506/causes-of-prehospital-misinterpretations-of-st-elevation-myocardial-infarction
#6
Nichole Bosson, Stephen Sanko, Ronald E Stickney, James Niemann, William J French, James G Jollis, Michael C Kontos, Tyson G Taylor, Peter W Macfarlane, Richard Tadeo, William Koenig, Marc Eckstein
OBJECTIVES: To determine the causes of software misinterpretation of ST elevation myocardial infarction (STEMI) compared to clinically identified STEMI to identify opportunities to improve prehospital STEMI identification. METHODS: We compared ECGs acquired from July 2011 through June 2012 using the LIFEPAK 15 on adult patients transported by the Los Angeles Fire Department. Cases included patients ≥18 years who received a prehospital ECG. Software interpretation of the ECG (STEMI or not) was compared with data in the regional EMS registry to classify the interpretation as true positive (TP), true negative (TN), false positive (FP), or false negative (FN)...
November 18, 2016: Prehospital Emergency Care
https://www.readbyqxmd.com/read/27777696/effect-of-remote-ischemic-post-conditioning-on-oxidative-stress-in-blood-of-stemi-patients-treated-with-primary-angioplasty
#7
Hassanali Lotfollahi, Mustafa Mohammadi, Samad Ghaffari, Reza Badalzadeh, Bahram Sohrabi, Naser Aslanabadi, Ahmad Separham, Ali Golmohammadi, Ali Abbasnejad, Mehri Roshani
Introduction: This study designed to use remote ischemic post conditioning (RIPC) as a protective strategy during percutaneous coronary intervention (PCI) in patients with ST segment elevation myocardial infarction (STEMI) to reduce myocardial cells damage due to reperfusion injury. Methods: Sixty-one patients were divided into test group (32 patients) receiving RIPC and control group (29 patients). Patients were included with first MI who had 20-80 years old. The RIPC protocol was applied on patients arm in three successive episodes during the opening of infarct-related artery (IRA)...
2016: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/27745858/immunohistological-analysis-of-intracoronary-thrombus-aspirate-in-stemi-patients-clinical-implications-of-pathological-findings
#8
Ana Blasco, Carmen Bellas, Leyre Goicolea, Ana Muñiz, Víctor Abraira, Ana Royuela, Susana Mingo, Juan Francisco Oteo, Arturo García-Touchard, Francisco Javier Goicolea
INTRODUCTION AND OBJECTIVES: Thrombus aspiration allows analysis of intracoronary material in patients with ST-segment elevation myocardial infarction. Our objective was to characterize this material by immunohistology and to study its possible association with patient progress. METHODS: This study analyzed a prospective cohort of 142 patients undergoing primary angioplasty with positive coronary aspiration. Histological examination of aspirated samples included immunohistochemistry stains for the detection of plaque fragments...
October 10, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27694532/heart-rate-at-admission-is-a-predictor-of-in-hospital-mortality-in-patients-with-acute-coronary-syndromes-results-from-58-european-hospitals-the-european-hospital-benchmarking-by-outcomes-in-acute-coronary-syndrome-processes-study
#9
Magnus T Jensen, Marta Pereira, Carla Araujo, Anti Malmivaara, Jean Ferrieres, Irene R Degano, Inge Kirchberger, Dimitrios Farmakis, Pascal Garel, Marina Torre, Jaume Marrugat, Ana Azevedo
AIMS: The purpose of this study was to investigate the relationship between heart rate at admission and in-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation acute coronary syndrome (NSTE-ACS). METHODS: Consecutive ACS patients admitted in 2008-2010 across 58 hospitals in six participant countries of the European Hospital Benchmarking by Outcomes in ACS Processes (EURHOBOP) project (Finland, France, Germany, Greece, Portugal and Spain)...
September 30, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27693166/-intracoronary-administration-of-antithrombotic-agents-via-a-perfusion-balloon-catheter-in-patients-with-st-segment-elevation-myocardial-infarction-presenting-with-massive-intraluminal-thrombus-and-failed-aspiration
#10
B Ajlani, G Gibault-Genty, G Cherif, E Blicq, S Azzaz, P Schiano, M Brami, L Sarfati, C Charbonnel, R Convers-Domart, B Livarek, J-L Georges
BACKGROUND: Massive intracoronary thrombus is associated with adverse procedural results including failed aspiration and unfavourable reperfusion. We aim to evaluate the effect of the intracoronary administration of antithrombotic agents via a perfusion catheter in patients with ST-segment elevation myocardial infarction (STEMI) presenting with a large thrombus burden and failed aspiration. METHODS: We retrospectively analyzed the thrombus burden, the TIMI grade flow, and the myocardial Blush in 25 consecutive STEMI patients with a large thrombus burden and failed manual aspiration, who received intracoronary infusion of glycoprotein IIb/IIIa inhibitors (N=17) or bivalirudine (N=8) via a 6F-infusion catheter (ClearWay™ RX) RESULTS: Mean age was 67±14 years, 16 patients (64 %) presented with anterior STEMI, and 7 (28 %) with cardiogenic shock...
November 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27681934/plasma-catestatin-in-patients-with-acute-coronary-syndrome
#11
Weixian Xu, Haiyi Yu, Hubing Wu, Siheng Li, Baoxia Chen, Wei Gao
OBJECTIVES: To measure plasma catestatin levels in patients with acute coronary syndrome and investigate whether there is an association between catestatin levels and long-term outcome. METHODS: Patients (n = 170) with suspected acute coronary syndrome who underwent emergency coronary angiography were enrolled, including 46 with acute ST-segment elevation myocardial infarction (STEMI), 89 with unstable angina pectoris (UAP), and 35 without coronary artery disease (CAD)...
2017: Cardiology
https://www.readbyqxmd.com/read/27681496/reperfusion-treatment-delays-amongst-patients-with-painless-st-segment-elevation-myocardial-infarction
#12
Pin Pin Pek, En Yun Loy, Win Wah, Andrew Fu Wah Ho, Huili Zheng, Stephanie Man Chung Fook-Chong, Terrance Siang Jin Chua, Tian Hai Koh, Khuan Yew Chow, Nan Liu, Marcus Eng Hock Ong
OBJECTIVE: Early reperfusion therapy in the treatment of ST segment elevation myocardial infarction (STEMI) patients can improve outcomes. Silent myocardial infarction is associated with poor prognosis, but little is known about its effect on treatment delays. We aimed to characterize STEMI patients presenting without complaints of pain to the emergency departments (EDs) in Singapore. METHODS: Retrospective data were requested from the Singapore Myocardial Infarction Registry (SMIR), a national level registry in Singapore...
September 29, 2016: CJEM
https://www.readbyqxmd.com/read/27667274/-efficacy-of-thrombolytic-therapy-using-reteplase-in-cases-with-acute-st-segment-elevation-myocardial-infarction-results-from-a-multicenter-clinical-trial
#13
X Y Liu, Y Zhang, M W Li, X P Wang, D D Qi, P Y Hao, H Zhang, Q Q Cheng, L S Zhao, C Y Gao, D Y Hu
Objective: To evaluate the efficacy and safety of intravenous thrombolytic therapy using reteplase in patients with acute ST-segment elevation myocardial infarction (STEMI). Method: A total of 73 hospitals from Henan province took part in this clinical trials during October 2012 to October 2014, 1 226 cases (1 014 male (82.7%), mean age 59.0 (51.0, 66.0) years) with acute STEMI received reteplase as thrombolytic agent.Reperfusion rate was judged according to the clinical symptoms, electrocardiogram, myocardial enzymes and heart rhythm, and the rate of cardiovascular events and bleeding events during hospitalization was also observed...
September 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/27635386/st-elevation-myocardial-infarction-risk-in-the-very-elderly
#14
Alessandra M Campos, Andrea Placido-Sposito, Wladimir M Freitas, Filipe A Moura, Maria Elena Guariento, Wilson Nadruz, Emilio H Moriguchi, Andrei C Sposito
BACKGROUND: Despite the high incidence and mortality of ST-segment elevation myocardial infarction (STEMI) among the very elderly, risk markers for this condition remain poorly defined. This study was designed to identify independent markers of STEMI among individuals carefully selected for being healthy or manifesting STEMI in < 24 h. METHODS: We enrolled participants aged 80 years or older of whom 50 were STEMI patients and 207 had never manifested cardiovascular diseases...
December 2016: BBA Clinical
https://www.readbyqxmd.com/read/27512881/defining-and-validating-comorbidities-and-procedures-in-icd-10-health-data-in-st-elevation-myocardial-infarction-patients
#15
Erik Youngson, Robert C Welsh, Padma Kaul, Finlay McAlister, Hude Quan, Jeffrey Bakal
Administrative health databases are used in research to define comorbid conditions, diagnosis, and procedures. Our objectives were to validate a diagnosis of ST-elevation myocardial infarction (STEMI) and invasive cardiac procedure coding against a comprehensive registry of STEMI patients and determine an optimal algorithm for defining comorbidities using administrative hospitalization and ambulatory databases, but without using a physician claims database, which is unavailable for use in many jurisdictions...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27436599/a-post-hoc-analysis-of-long-term-prognosis-after-exenatide-treatment-in-patients-with-st-segment-elevation-myocardial-infarction
#16
Kasper Kyhl, Jacob Lønborg, Niels Vejlstrup, Henning Kelbæk, Steffen Helqvist, Lene Holmvang, Erik Jørgensen, Kari Saunamäki, Hans Erik Bøtker, Peter Clemmensen, Lars Køber, Marek Treiman, Thomas Engstrøm
AIMS: We aimed to assess the effect of exenatide treatment as an adjunct to primary percutaneous coronary intervention (PCI) on long-term clinical outcome. METHODS AND RESULTS: We performed a post hoc analysis in 334 patients with a first STEMI included in a previous study randomised to exenatide (n=175) or placebo (n=159) as an adjunct to primary PCI. The primary endpoint was a composite of all-cause mortality and admission for heart failure during a median follow-up of 5...
July 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27377301/five-year-follow-up-of-polymer-free-sirolimus-and-probucol-eluting-stents-versus-new-generation-zotarolimus-eluting-stents-in-patients-presenting-with-st-elevation-myocardial-infarction
#17
Roisin Colleran, Sebastian Kufner, Yukinori Harada, Daniele Giacoppo, Salvatore Cassese, Janika Repp, Jens Wiebe, Raphaela Lohaus, Annalena Lahmann, Simon Schneider, Tareq Ibrahim, Karl-Ludwig Laugwitz, Adnan Kastrati, Robert A Byrne
BACKGROUND: Patients with ST-segment elevation myocardial infarction (STEMI) undergoing drug-eluting stent (DES) implantation are at increased risk of late adverse events, partly explained by an exaggerated inflammatory reaction to durable-polymer stent coatings. OBJECTIVES: We sought to investigate whether implantation of polymer-free DES would reduce this risk. METHODS: In the ISAR-TEST 5 (the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol- and Zotarolimus-Eluting Stents) trial, patients were randomly allocated to receive a polymer-free sirolimus- and probucol-eluting stent or a new generation durable-polymer zotarolimus-eluting stent...
February 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27320957/increased-rho-kinase-activity-predicts-worse-cardiovascular-outcome-in-st-segment-elevation-myocardial-infarction-patients
#18
Xiaohui Li, Xing Wu, Hongwei Li, Hui Chen, Yongliang Wang, Weiping Li, Xiaosong Ding, Xu Hong
BACKGROUND: Few clinical studies have assessed Rho kinase (ROCK) in patients with dia-betes mellitus (DM) and ST-segment elevation myocardial infarction (STEMI). This study aimed to determine whether ROCK activity in circulating leukocytes is increased in STEMI patients with DM and whether ROCK activity predicts the onset of cardiovascular events. METHODS: Blood samples were collected from 60 STEMI patients, divided into non-diabetes mellitus (NDM) and DM groups...
2016: Cardiology Journal
https://www.readbyqxmd.com/read/27282672/circulating-micrornas-in-patients-with-st-elevation-myocardial-infarction
#19
Ufuk Eryılmaz, Çağdaş Akgüllü, Nurettin Beşer, Ömer Yıldız, İmran Kurt Ömürlü, Bülent Bozdoğan
OBJECTIVE: The aim of this study was to evaluate the expression levels of cardiac-related circulating microRNAs (miRNAs) in ST-elevation myo- cardial infarction (STEMI) patients. METHODS: This study has a prospective experimental cohort design. A total of 12 consecutive patients with acute chest pain within 12 h admit- ted to emergency department (STEMI group) and 13 adult patients with normal coronary angiography during the same period were enrolled (control group) in this study...
June 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27279793/gender-related-survival-differences-in-st-elevation-myocardial-infarction-patients-treated-with-primary-pci
#20
Vojko Kanic, Maja Vollrath, Franjo Husam Naji, Andreja Sinkovic
BACKGROUND: Data about gender as an independent risk factor for death in ST-elevation myocardial infarction (STEMI) patients is still contrasting. Aim was to assess how gender influences in-hospital and long-term all-cause mortality in STEMI patients with primary percutaneous coronary intervention (PCI) in our region. METHODS: We analysed data from 2069 STEMI patients undergoing primary PCI in our institution from January 2009-December 2014, of whom 28.9% were women...
2016: International Journal of Medical Sciences
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