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https://www.readbyqxmd.com/read/29444349/suicidal-ideation-in-first-episode-psychosis-fep-examination-of-symptoms-of-depression-and-psychosis-among-individuals-in-an-early-phase-of-treatment
#1
Lindsay A Bornheimer
First-episode psychosis (FEP) is a particularly high-risk period for suicide, in which risk elevates by 60% within a first year of treatment as compared to later stages of illness. To date, much of the literature has focused on individuals with a longer duration of psychosis; thus, there is an urgency for research to examine suicide risk among individuals in FEP in the beginning stage of treatment. This study aimed to identify the relationships between demographic characteristics, symptoms of depression, psychosis (particularly positive symptoms of psychosis), and suicidal ideation among individuals in FEP...
February 14, 2018: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/29444165/frequency-trends-and-antecedents-of-severe-maternal-depression-after-three-million-u-s-births
#2
Urbano L França, Michael L McManus
BACKGROUND: Postpartum depression carries adverse consequences for mothers and children, so widespread screening during primary care visits is recommended. However, the rates, timing, and factors associated with significant depressive episodes are incompletely understood. METHODS AND FINDINGS: We examined the Healthcare Cost and Utilization Project (HCUP) State Inpatient, Emergency Department, and Ambulatory Surgery and Services Databases from California (2005-2011) and Florida (2005-2012)...
2018: PloS One
https://www.readbyqxmd.com/read/29443422/linking-dendroecology-and-association-genetics-in-natural-populations-stress-responses-archived-in-tree-rings-associate-with-snp-genotypes-in-silver-fir-abies-alba-mill
#3
K Heer, D Behringer, A Piermattei, C Bässler, R Brandl, B Fady, H Jehl, S Liepelt, S Lorch, A Piotti, G G Vendramin, M Weller, B Ziegenhagen, U Büntgen, L Opgenoorth
Genetic association studies in forest trees would greatly benefit from information on the response of trees to environmental stressors over time, which can be provided by dendroecological analysis. Here, we jointly analyzed dendroecological and genetic data of surviving silver fir trees to explore the genetic basis of their response to the iconic stress episode of the 1970s and 80s that led to large-scale forest dieback in Central Europe and has been attributed to air pollution. Specifically, we derived dendrophenotypic measures from 190 trees in the Bavarian Forest that characterize the resistance, resilience and recovery during this growth depression, and in the drought year in 1976...
February 14, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29436490/subthalamic-stimulation-and-neuropsychiatric-symptoms-in-parkinson-s-disease-results-from-a-long-term-follow-up-cohort-study
#4
Marie Abbes, Eugénie Lhommée, Stéphane Thobois, Hélène Klinger, Emmanuelle Schmitt, Amélie Bichon, Anna Castrioto, Jing Xie, Valérie Fraix, Andrea Kistner, Pierre Pélissier, Éric Seigneuret, Stéphan Chabardès, Patrick Mertens, Emmanuel Broussolle, Elena Moro, Paul Krack
BACKGROUND: Reports on behavioural outcomes after subthalamic nucleus deep brain stimulation in Parkinson's disease are controversial and limited to short-term data. Long-term observation in a large cohort allows a better counselling and management. METHODS: To determine whether a long-term treatment with subthalamic stimulation induces or reduces impulse control behaviours, neuropsychiatric fluctuations and apathy, 69 patients treated with subthalamic stimulation are prospectively and retrospectively assessed using Ardouin Scale of Behavior in Parkinson's Disease before and after 3-10 years of stimulation...
February 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29436331/impact-of-adherence-to-antidepressants-on-long-term-prescription-opioid-use-cessation
#5
Jeffrey F Scherrer, Joanne Salas, Mark D Sullivan, Brian K Ahmedani, Laurel A Copeland, Kathleen K Bucholz, Thomas Burroughs, F David Schneider, Patrick J Lustman
BACKGROUND: Depression contributes to persistent opioid analgesic use (OAU). Treating depression may increase opioid cessation. Aims To determine if adherence to antidepressant medications (ADMs) v. non-adherence was associated with opioid cessation in patients with a new depression episode after >90 days of OAU. METHOD: Patients with non-cancer, non-HIV pain (n = 2821), with a new episode of depression following >90 days of OAU, were eligible if they received ≥1 ADM prescription from 2002 to 2012...
February 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29436160/patterns-and-predictors-of-exhaustion-episodes-in-patients-with-stable-copd-a-longitudinal-study
#6
Francesc Medina-Mirapeix, Roberto Bernabeu-Mora, Luz María Giménez-Giménez, Joaquina Montilla-Herrador, Jose Antonio García-Vidal, Josep Benítez-Martínez
BACKGROUND AND OBJECTIVE: Exhaustion is the perception of low energy. Little is known about how exhaustion persists, remits or reappears over time in patients with chronic obstructive pulmonary disease (COPD) or how to predict these events. We determined the likelihood of transitions between states of exhaustion and no exhaustion among patients with stable COPD followed up for 2 years. We investigated combinations of potential factors for their abilities to predict new-onset exhaustion episodes...
February 12, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29433074/the-relationship-between-inflammatory-state-and-quantity-of-affective-episodes-in-bipolar-disorder
#7
Robert Queissner, René Pilz, Nina Dalkner, Armin Birner, Susanne A Bengesser, Martina Platzer, Frederike T Fellendorf, Nora Kainzbauer, Simone Herzog-Eberhard, Carlo Hamm, Bernd Reininghaus, Sieglinde Zelzer, Harald Mangge, Rodrigo B Mansur, Roger S McIntyre, Hans-Peter Kapfhammer, Eva Z Reininghaus
OBJECTIVES: Immunological/inflammatory processes have been proposed to play an important role in the pathophysiology of mood disorders, including bipolar disorder (BD). The present study aimed to examine the influence of immune activation, measured on the basis of inflammatory markers, on the course of illness, proxied by the number of affective episodes, in patients with BD. METHODS: We investigated the relationship between high-sensitive CRP (hsCRP) and Interleukin 6 (IL-6), two inflammatory markers and characteristics of course of illness (e...
February 3, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29432500/large-animals-as-potential-models-of-human-mental-and-behavioral-disorders
#8
REVIEW
Michał Danek, Janusz Danek, Aleksander Araszkiewicz
Many animal models in different species have been developed for mental and behavioral disorders. This review presents large animals (dog, ovine, swine, horse) as potential models of this disorders. The article was based on the researches that were published in the peer-reviewed journals. Aliterature research was carried out using the PubMed database. The above issues were discussed in the several problem groups in accordance with the WHO International Statistical Classification of Diseases and Related Health Problems 10thRevision (ICD-10), in particular regarding: organic, including symptomatic, disorders; mental disorders (Alzheimer's disease and Huntington's disease, pernicious anemia and hepatic encephalopathy, epilepsy, Parkinson's disease, Creutzfeldt-Jakob disease); behavioral disorders due to psychoactive substance use (alcoholic intoxication, abuse of morphine); schizophrenia and other schizotypal disorders (puerperal psychosis); mood (affective) disorders (depressive episode); neurotic, stress-related and somatoform disorders (posttraumatic stress disorder, obsessive-compulsive disorder); behavioral syndromes associated with physiological disturbances and physical factors (anxiety disorders, anorexia nervosa, narcolepsy); mental retardation (Cohen syndrome, Down syndrome, Hunter syndrome); behavioral and emotional disorders (attention deficit hyperactivity disorder)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29429423/aberrant-topographical-organization-in-default-mode-network-in-first-episode-remitted-geriatric-depression-a-graph-theoretical-analysis
#9
Yan Zhu, Dongqing Wang, Zhe Liu, Yuefeng Li
BACKGROUND: Neuroimaging studies have shown that major depressive disorder is associated with altered activity patterns of the default-mode network (DMN). In this study, we sought to investigate the topological organization of the DMN in patients with remitted geriatric depression (RGD) and whether RGD patients would be more likely to show disrupted topological configuration of the DMN during the resting-state. METHODS: Thirty-three RGD patients and thirty-one healthy control participants underwent clinical and cognitive evaluations as well as resting-state functional magnetic resonance imaging scans...
February 12, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29428773/self-perceived-personality-characteristics-in-seasonal-affective-disorder-and-their-implications-for-severity-of-depression
#10
Liv Vadskjær Hjordt, Vibeke H Dam, Brice Ozenne, Ida Hageman, Brenda Mc Mahon, Erik Lykke Mortensen, Gitte M Knudsen, Dea Siggaard Stenbæk
The personality traits Neuroticism and Extraversion may be involved in the development of seasonal affective disorder (SAD). However, the impact of personality traits on SAD severity and whether such self-reported traits fluctuate with season is unknown. We investigated the association between Neuroticism, as acquired in a symptom-free phase and depression severity in individuals with SAD and seasonal changes in personality traits in individuals with SAD compared to healthy controls. Twenty-nine individuals diagnosed with SAD and thirty demographically matched controls completed the NEO Personality Inventory-Revised and the Major Depression Inventory twice: in summer when individuals with SAD were symptom-free, and in winter when they experienced SAD symptoms...
February 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29424401/-association-between-adverse-childhood-experiences-with-depression-in-adults-consulting-in-primary-care
#11
Verónica Vitriol, Alfredo Cancino, Marcelo Leiva-Bianchi, Carlos Serrano, Soledad Ballesteros, Soledad Potthoff, Cristián Cáceres, Marcela Ormazábal, Andrea Asenjo
BACKGROUND: Traumatic experiences during childhood may influence the development of mental disorders during adulthood. AIM: To determine clinical and psychosocial variables that are associated with a higher frequency of adverse childhood experiences (ACE) in patients who consult for depression in Primary Health Care clinics in Chile. MATERIAL AND METHODS: A socio-demographic interview, the mini international neuropsychiatric interview (MINI), a screening for ACE, a questionnaire for partner violence (PV), the Life Experiences Survey (LES) and the Hamilton Rating Scale for Depression (HRDS) were applied to 394 patients with major depression (87% women)...
September 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29423624/treatment-initiation-for-new-episodes-of-depression-in-primary-care-settings
#12
Beth Waitzfelder, Christine Stewart, Karen J Coleman, Rebecca Rossom, Brian K Ahmedani, Arne Beck, John E Zeber, Yihe G Daida, Connie Trinacty, Samuel Hubley, Gregory E Simon
BACKGROUND: Depression is prevalent and costly, but despite effective treatments, is often untreated. Recent efforts to improve depression care have focused on primary care settings. Disparities in treatment initiation for depression have been reported, with fewer minority and older individuals starting treatment. OBJECTIVE: To describe patient characteristics associated with depression treatment initiation and treatment choice (antidepressant medications or psychotherapy) among patients newly diagnosed with depression in primary care settings...
February 8, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29421266/neural-correlates-of-working-memory-in-first-episode-and-recurrent-depression-an-fmri-study
#13
Dilara Yüksel, Bruno Dietsche, Carsten Konrad, Udo Dannlowski, Tilo Kircher, Axel Krug
BACKGROUND: Patients suffering from major depressive disorder (MDD) show deficits in working memory (WM) performance accompanied by bilateral fronto-parietal signal changes. It is unclear whether patients with a first depressive episode (FDE) exhibit the same BOLD signal changes as patients with recurrent depressive episodes (RDE). METHODS: We investigated seventy-four MDD inpatients (48 RDE, 26 FDE) and 74 healthy control (HC) subjects performing an n-back WM task (0-back, 2-back, 3-back condition) in a 3T-fMRI...
February 5, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29421173/effects-of-chlorpromazine-on-sleep-quality-clinical-and-emotional-measures-among-patients-with-schizophrenia
#14
Qingli Meng, Rongqin Li, Feng Hou, Qiulan Zhang
OBJECTIVES: The present study was aimed to examine the effects of chlorpromazine on sleep quality, clinical and emotional measures in people suffering from schizophrenia. PATIENTS AND METHODS: Twenty-five patients with schizophrenia or schizoaffective disorder were enrolled in this study. Our study included a one-week running-in no-treatment period and two-month experimental period. Patients received chlorpromazine during the experimental period. The baseline and treatment outcome were recorded...
February 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29420786/one-day-behavioral-intervention-for-distressed-veterans-with-migraine-results-of-a-multimethod-pilot-study
#15
C Huddleston, L Martin, K Woods, L Dindo
Introduction: Migraine, a chronic neurological disorder characterized by episodic severe headache pain and functional impairment, affects approximately 12% of the general US population. Veterans returning from Iraq or Afghanistan have two to four times the incidence of migraine of the general population. Veterans with migraines are more than twice as likely to have comorbid psychiatric conditions as veterans without migraines, with depression and post-traumatic stress disorder being most prevalent...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29419640/a-mixed-program-of-psychoeducational-and-psychological-rehabilitation-for-patients-with-bipolar-disorder-in-a-day-hospital-setting
#16
Giovanni Camardese, Massimo Vasale, Lucio DʼAlessandris, Marianna Mazza, Riccardo Serrani, Federico Travagliati, Coco Walstra, Leonardo Zaninotto, Beniamino Leone, Marco Di Nicola, Raffaella Franza, Giuseppe Marano, Lucio Rinaldi, Luigi Janiri
The present study describes a new mixed program of psychoeducational and psychological interventions for bipolar patients, applicable during everyday practice. Thirty-two bipolar patients recruited at a psychiatric day-hospital service have been admitted to a program consisting of 30 meetings and 2 follow-ups at 6 and 12 months. The psychoeducational support determined a general improvement of all included patients. At baseline, patients with residual depression had higher Hamilton Depression Rating Scale (HDRS) scores than euthymic patients (mean score ± SD: 21...
February 6, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29417976/serum-cortisol-levels-and-neuropsychological-impairments-in-patients-diagnosed-with-fibromyalgia
#17
Ernesto Barceló-Martinez, Melissa Gelves-Ospina, Edgar Navarro Lechuga, Ricardo F Allegri, Erick Orozco-Acosta, Juan C Benítez-Agudelo, Alexandra León-Jacobus, Néstor F Román
OBJECTIVE: To describe the relationship between neuropsychological variables and serum cortisol levels as a measure of physiological stress in patients with fibromyalgia. METHODOLOGY: A sample of 60 women was intentionally selected: 30 with Fibromyalgia diagnosis and 30 with normal controls. Cortisol levels were determined using two blood samples (AM and PM) and a neuropsychological and emotional battery was applied with a standardized protocol in Colombian population to evaluate different cognitive domains...
January 2018: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29417833/clinical-response-to-treatment-in-inpatients-with-depression-correlates-with-changes-in-activity-levels-and-psychomotor-speed
#18
Ian Re Averill, Marie Crowe, Chris M Frampton, Ben Beaglehole, Cameron J Lacey, Jennifer Jordan, Lynere D Wilson, Katie M Douglas, Richard J Porter
BACKGROUND: Monitoring clinical response to treatment in depressed inpatients, particularly identifying early improvement, may be sub-optimal. This may impact adversely on patients through longer admissions and sub-optimal pharmacotherapy. Psychomotor speed is a prominent neuropsychological function which changes as recovery occurs. This study examines simple techniques used to quantify psychomotor change and their potential to contribute to monitoring recovery. METHODS: Activity levels were continuously monitored in patients diagnosed with a major depressive episode from four acute psychiatric wards using two actigraphs (commercial and scientific) for 3 weeks and linear regression used to calculate a gradient to express rate of change...
February 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29417206/depressive-residual-symptoms-are-associated-with-illness-course-characteristics-in-a-sample-of-outpatients-with-bipolar-disorder
#19
Gianluca Serafini, Gustavo H Vazquez, Xenia Gonda, Maurizio Pompili, Zoltan Rihmer, Mario Amore
Rates of 50-70% of residual symptoms referring to subsyndromal manifestations between episodes that do not meet the required criteria for episode definition were reported in bipolar disorder (BD). However, the specific role of these symptoms on the course of BD patients is poorly understood; thus, we aimed to investigate factors associated with depressive residual symptoms. Overall, 255 currently euthymic BD outpatients on maintenance treatment, including 95 (37.2%) males and 160 (62.8%) females, were consecutively recruited at the Section of Psychiatry, Department of Neuroscience, University of Genoa (Italy) and underwent detailed structured interviews, comprehensive clinical interviews, and clinical record reviews for assessment/collection of relevant information concerning the course of illness and clinical status including cross-referral of all available information...
February 7, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29416859/applying-realistic-medicine-to-intrathecal-opioid-utilisation-in-scotland-do-we-have-a-standardised-approach
#20
Robert Hart, Gordon Burns, Susan Smith
Intrathecal opioids (ITOs) are commonly administered as part of a multimodal anaesthetic strategy for a variety of surgical procedures. The evolution of laparoscopic surgical techniques has seen the popularity of ITOs increase as they are effective, well tolerated and lack the cardiovascular side effects associated with epidural infusions. The risk of delayed respiratory depression remains a concern; therefore, high-quality post-operative monitoring is vital. The evidence regarding the practicalities of ITO administration such as opioid dose, type, side effect prevalence and ideal post-operative care arrangements are sparse...
February 2018: British Journal of Pain
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