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https://www.readbyqxmd.com/read/29674601/the-relationship-between-the-number-of-manic-episodes-and-oxidative-stress-indicators-in-bipolar-disorder
#1
Süleyman Akarsu, Abdullah Bolu, Emre Aydemir, Selma Bozkurt Zincir, Yasemin Gülcan Kurt, Serkan Zincir, Murat Erdem, Özcan Uzun
Objective: Bipolar disorder (BD) is a chronic mood disorder characterized by recurrent episodes that has a lifetime prevalence of 0.4- 5.5%. The neurochemical mechanism of BD is not fully understood. Oxidative stress in neurons causes lipid peroxidation in proteins associated with neuronal membranes and intracellular enzymes and it may lead to dysfunction in neurotransmitter reuptake and enzyme activities. These pathological processes are thought to occur in brain regions associated with affective functions and emotions in BD...
April 20, 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/29673721/-prevalence-of-mental-disorders-in-the-general-population-of-burkina-faso
#2
A Ouédraogo, J G Ouango, K Karfo, P Goumbri, D Nanéma, B Sawadogo
OBJECTIVES: To determine, with the use of the Mini-International Neuropsychiatric Interview (MINI), the prevalence of mental disorders in the general population of Burkina Faso; To identify the factors associated with the occurrence of these disorders. METHODS: We conducted a cross-sectional descriptive and analytical survey of a representative sample of the general population aged 18 years and over (n=2587). The only non-inclusion criterion was absence from the place of residence during the investigation period for whatever reason...
April 16, 2018: L'Encéphale
https://www.readbyqxmd.com/read/29672141/health-care-utilization-and-expenditures-of-homeless-family-members-before-and-after-emergency-housing
#3
Robin E Clark, Linda Weinreb, Julie M Flahive, Robert W Seifert
OBJECTIVES: To describe longitudinal health service utilization and expenditures for homeless family members before and after entering an emergency shelter. METHODS: We linked Massachusetts emergency housing assistance data with Medicaid claims between July 2008 and June 2015, constructing episodes of health care 12 months before and 12 months after families entered a shelter. We modeled emergency department visits, hospital admissions, and expenditures over the 24-month period separately for children and adults...
April 19, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29671955/smoking-drinking-and-depression-comorbidity-in-head-and-neck-cancer-patients-undergoing-radiotherapy
#4
Kristen McCarter, Amanda L Baker, Benjamin Britton, Luke Wolfenden, Chris Wratten, Judith Bauer, Sean A Halpin, Gregory Carter, Alison K Beck, Lucy Leigh, Christopher Oldmeadow
We aimed to determine the prevalence and co-occurrence of tobacco smoking, alcohol consumption, and depressive symptoms among a sample of head and neck cancer (HNC) patients undergoing radiotherapy. A total of 307 HNC patients participated in a multi-site stepped-wedge randomized controlled trial (RCT) evaluating the effectiveness of a dietitian-delivered health behavior intervention in patients with HNC undergoing radiotherapy. During week one of radiotherapy patients completed measures of smoking, alcohol consumption, and level of depression...
April 19, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29671796/does-discrimination-explain-high-risk-of-depression-among-high-income-african-american-men
#5
Shervin Assari, Maryam Moghani Lankarani, Cleopatra Howard Caldwell
Background: Higher socioeconomic status is known to decrease the risk for poor mental health overall. However, African American males of higher socioeconomic status (SES) are at an increased risk for having a major depressive episode (MDE). It is not known whether perceived discrimination (PD) explains this risk. The current study used nationally representative data to explore the role of PD in explaining the association between high-SES and having MDE among African American men. Methods: The National Survey of American Life (NSAL), 2003, included 4461 American adults including 1271 African American men...
April 19, 2018: Behavioral Sciences
https://www.readbyqxmd.com/read/29670407/first-episode-psychosis-as-the-initial-presentation-of-multiple-sclerosis-a-case-report
#6
Athena Enderami, Rose Fouladi, Seyed Hamzeh Hosseini
Background: Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system (CNS). MS with episode of psychosis is a rare entity, and to the best of our knowledge, no case has been reported from Iran till date. Case presentation: We report a case of MS with first-episode psychosis in a 27-year-old single man with no history of psychiatric disorder or drug abuse. The patient developed neurological symptoms after 3 months and was finally diagnosed as a case of MS...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29669175/antidepressants-for-preventing-postnatal-depression
#7
REVIEW
Emma Molyneaux, Laurence A Telesia, Carol Henshaw, Elizabeth Boath, Eleanor Bradley, Louise M Howard
BACKGROUND: Depression is common in the postnatal period and can lead to adverse effects on the infant and wider family, in addition to the morbidity for the mother. It is not clear whether antidepressants are effective for the prevention of postnatal depression and little is known about possible adverse effects for the mother and infant, particularly during breastfeeding. This is an update of a Cochrane Review last published in 2005. OBJECTIVES: To assess the effectiveness of antidepressant medication for the prevention of postnatal depression, in comparison with any other treatment, placebo or standard care...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29667796/isotretinoin-the-ups-are-just-as-troubling-as-the-downs
#8
Jay M Truitt, Jason S Reichenberg, Kevin G Sharghi, Shirlene M Sampson, Randall K Roenigk, Michelle Magid
INTRODUCTION: Isotretinoin, previously marketed as Accutane®, is an oral retinoid medication that is used to treat acne and other cutaneous disorders. Although the data is conflicting, previous reports suggest a causal relationship between isotretinoin and depression. When reviewing these previous reports, many patients who were diagnosed as 'depressed' did not undergo a thorough psychiatric evaluation and/or were not diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM)...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29666432/genetic-validation-of-bipolar-disorder-identified-by-automated-phenotyping-using-electronic-health-records
#9
Chia-Yen Chen, Phil H Lee, Victor M Castro, Jessica Minnier, Alexander W Charney, Eli A Stahl, Douglas M Ruderfer, Shawn N Murphy, Vivian Gainer, Tianxi Cai, Ian Jones, Carlos N Pato, Michele T Pato, Mikael Landén, Pamela Sklar, Roy H Perlis, Jordan W Smoller
Bipolar disorder (BD) is a heritable mood disorder characterized by episodes of mania and depression. Although genomewide association studies (GWAS) have successfully identified genetic loci contributing to BD risk, sample size has become a rate-limiting obstacle to genetic discovery. Electronic health records (EHRs) represent a vast but relatively untapped resource for high-throughput phenotyping. As part of the International Cohort Collection for Bipolar Disorder (ICCBD), we previously validated automated EHR-based phenotyping algorithms for BD against in-person diagnostic interviews (Castro et al...
April 18, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29665490/smaller-hippocampal-volume-in-current-but-not-in-past-depression-in-comparison-to-healthy-controls-minor-evidence-from-an-older-adults-sample
#10
Ismaïl Bensassi, Jorge Lopez-Castroman, Jerome J Maller, Chantal Meslin, Marilyn Wyart, Karen Ritchie, Philippe Courtet, Sylvaine Artero, Raffaella Calati
BACKGROUND: Structural neuroimaging studies revealed a consistent pattern of volumetric reductions in both hippocampus (HC) and anterior cingulate cortex (ACC) of individuals with major depressive episode(s) (MDE). This study investigated HC and ACC volume differences in currently depressed individuals (n = 150), individuals with a past lifetime MDE history (n = 79) and healthy controls (n = 287). METHODS: Non-demented individuals were recruited from a cohort of community-dwelling older adults (ESPRIT study)...
April 9, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29663468/problematic-eating-behaviors-and-psychopathology-in-patients-undergoing-bariatric-surgery-the-mediating-role-of-loss-of-control-eating
#11
Eva M Conceição, Marta de Lourdes, Ana Pinto-Bastos, Ana Rita Vaz, Isabel Brandão, Sofia Ramalho
OBJECTIVE: This study compares different problematic eating behaviors (PEBs; objective [OBE]/subjective [SBE] binge-eating and compulsive [CG]/noncompulsive [NCG] grazing) in relation to the severity of loss of control (LOC) and psychopathology. We also investigate LOC as a mediator between PEBs and psychopathology. METHOD: This cross-sectional study assessed a group of patients before bariatric surgery (n = 163), and a group of bariatric patients 12 months or more after surgery (n = 131)...
April 17, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29663082/chemical-meningitis-from-a-leaking-craniopharyngioma-a-case-report
#12
David Hakizimana, Lars Poulsgaard, Kåre Fugleholm
Recurrent chemical meningitis from cyclic leakage of cyst content from a craniopharyngioma is a rare phenomenon. Here, we report a case of leaking cystic craniopharyngioma presenting with recurrent episodes of sterile meningitis, depression, and paranoia. The diagnosis after an initial craniotomy and exploration was hypophysitis. Signs and symptoms were not alleviated by puncture and biopsy of the tumour but they disappeared after complete resection with a final histological diagnosis of craniopharyngioma.
April 16, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29661027/social-determinants-of-health-and-preclinical-glycemic-control-in-newly-diagnosed-first-episode-psychosis-patients
#13
Franz Veru-Lesmes, Aldanie Rho, Suzanne King, Ridha Joober, Marita Pruessner, Ashok Malla, Srividya N Iyer
BACKGROUND: The abnormally high incidence of disorders of glucose metabolism (DGM) in psychotic-spectrum disorders (PSD) has often been attributed to the side effects of antipsychotics and unhealthy lifestyles. The influence of social determinants of health has been largely ignored, despite ample evidence linking social adversity with both PSD and DGM. The aim of this study is to examine the influence of well-established social determinants of health on preclinical levels of glycated hemoglobin (HbA1c) in a sample of first-episode psychosis (FEP) patients...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29659205/executive-function-predicts-antidepressant-treatment-noncompletion-in-late-life-depression
#14
Pilar Cristancho, Eric J Lenze, David Dixon, J Philip Miller, Benoit H Mulsant, Charles F Reynolds, Meryl A Butters
OBJECTIVE: To examine whether executive function (EF) is associated with nonremission and noncompletion of antidepressant pharmacotherapy in older adults with depression. DESIGN: In this prospective study (July 2009 to May 2014), older adults (aged ≥ 60 years; n = 468) with a DSM-IV-defined major depressive episode diagnosed via structured interview received 12 weeks of venlafaxine extended release with the goal of achieving remission. A hypothesis was made that worse baseline EF would predict both nonremission and noncompletion (primary outcomes)...
April 3, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29659120/patterns-of-depressive-symptom-remission-during-the-treatment-of-seasonal-affective-disorder-with-cognitive-behavioral-therapy-or-light-therapy
#15
Jonah Meyerhoff, Michael A Young, Kelly J Rohan
BACKGROUND: To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light therapy (LT). METHOD: One hundred seventy-seven adults with SAD in a depressive episode were randomized to 6-weeks of CBT-SAD (n = 88) or LT (n = 89)...
April 16, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29656261/young-adult-cognitive-ability-and-subsequent-major-depression-in-a-cohort-of-666-804-danish-men
#16
Gunhild Tidemann Christensen, Maarten Pieter Rozing, Erik Lykke Mortensen, Kaare Christensen, Merete Osler
BACKGROUND: Early life cognitive ability (CA) might influence the risk of developing major depression (MD). The aim was to investigate the association between young adult CA and subsequent MD in relation to different MD disease characteristics. METHODS: Information on CA was assessed at conscription board examinations 1957-1984 (mean age 19 years) and information on MD was based on hospital diagnosis retrieved from Danish Patient registers 1969-2015. Associations between CA and MD were examined using Cox regression analyses...
April 5, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29653349/the-role-of-lifetime-anxiety-history-in-the-course-of-bipolar-spectrum-disorders
#17
Madison K Titone, Rachel D Freed, Jared K O'Garro-Moore, Andrew Gepty, Tommy H Ng, Jonathan P Stange, Lyn Y Abramson, Lauren B Alloy
Individuals with bipolar spectrum disorder (BSD) frequently meet criteria for comorbid anxiety disorders, and anxiety may be an important factor in the etiology and course of BSDs. The current study examined the association of lifetime anxiety disorders with prospective manic/hypomanic versus major depressive episodes. Participants were 244 young adults (aged 17-26) with milder forms of BSDs (i.e., bipolar-II, cyclothymia, BD-NOS). First, bivariate analyses assessed differences in baseline clinical characteristics between participants with and without DSM-IV anxiety diagnoses...
April 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29653348/increased-oxidative-stress-in-the-mitochondria-isolated-from-lymphocytes-of-bipolar-disorder-patients-during-depressive-episodes
#18
Samira S Valvassori, Daniela V Bavaresco, Gustavo Feier, Kelen Cechinel-Recco, Amanda V Steckert, Roger B Varela, Cenita Borges, Milena Carvalho-Silva, Lara M Gomes, Emílio L Streck, João Quevedo
The present study aims to investigate the oxidative stress parameters in isolated mitochondria, as well as looking at mitochondrial complex activity in patients with Bipolar Disorder (BD) during depressive or euthymic episodes. This study evaluated the levels of mitochondrial complex (I, II, II-III and IV) activity in lymphocytes from BD patients. We evaluated the following oxidative stress parameters: superoxide, thiobarbituric acid reactive species (TBARS) and carbonyl levels in submitochondrial particles of lymphocytes from bipolar patients...
April 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29652947/-predictors-of-remission-from-major-depressive-disorder-in-secondary-care
#19
Lilian Salvo, Sandra Saldivia, Carlos Parra, Manuel Cifuentes, Claudio Bustos, Paola Acevedo, Marcela Díaz, Mitza Ormazabal, Ivonne Guerra, Nicol Navarrete, Verónica Bravo, Andrea Castro
Background The knowledge of predictive factors in depression should help to deal with the disease. Aim To assess potential predictors of remission of major depressive disorders (MDD) in secondary care and to propose a predictive model. Material and Methods A 12 month follow-up study was conducted in a sample of 112 outpatients at three psychiatric care centers of Chile, with baseline and quarterly assessments. Demographic, psychosocial, clinical and treatment factors as potential predictors, were assessed. A clinical interview with the checklist of DSM-IV diagnostic criteria, the Hamilton Depression Scale and the List of Threatening Experiences and Multidimensional Scale of Perceived Social Support were applied...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29649805/comparing-the-efficacy-of-cbasp-with-two-versions-of-cbt-for-depression-in-a-routine-care-center-a-randomized-clinical-trial
#20
Winfried Rief, Gabi Bleichhardt, Katharina Dannehl, Frank Euteneuer, Katrin Wambach
BACKGROUND: The cognitive-behavioral analysis system of psychotherapy (CBASP) was developed for the treatment of chronic, early-onset depression. However, it is unclear whether this approach can be recommended for depression in general (episodic and chronic), and no direct comparisons between CBASP with different versions of cognitive-behavioral therapy (CBT) exist. METHODS: A randomized controlled trial compared 3 treatment conditions (all lasting 16 sessions) with a waiting list group (WL): CBASP, CBT with a focus on physical exercise (CBT-E), and CBT with a focus on pleasurable, low-energy and mindful activities (CBT-M)...
April 12, 2018: Psychotherapy and Psychosomatics
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