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https://www.readbyqxmd.com/read/29453208/parent-reported-prevalence-and-persistence-of-19-common-child-health-conditions
#1
Tracy Liu, Raghu Lingam, Kate Lycett, Fiona K Mensah, Joshua Muller, Harriet Hiscock, Md Hamidul Huque, Melissa Wake
OBJECTIVE: To estimate prevalence and persistence of 19 common paediatric conditions from infancy to 14-15 years. DESIGN: Population-based prospective cohort study. SETTING: Australia. PARTICIPANTS: Parallel cohorts assessed biennially from 2004 to 2014 from ages 0-1 and 4-5 years to 10-11 and 14-15 years, respectively, in the Longitudinal Study of Australian Children. MAIN OUTCOME MEASURES: 19 health conditions: 17 parent-reported, 2 (overweight/obesity, obesity) directly assessed...
February 16, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29447051/targeting-crosstalk-between-nuclear-factor-erythroid-derived-2-like-2-and-nuclear-factor-kappa-beta-pathway-by-nrf2-activator-dimethyl-fumarate-in-epileptogenesis
#2
Neha Singh, Sheekha Vijayanti, Lekha Saha
Epilepsy is a complex, chronic neurological disorder characterized by increased and abnormal synchronization of neuronal electrical activity, which is manifested as seizures. It is associated with many comorbid conditions such as depression, anxiety, sleep disorder, psychiatric disorder etc. which consequently causes higher mortality rate. The understanding of its cellular and molecular mechanism is partial, because of which it remains an ongoing health problem, despite the increasing availability of newer antiepileptic drugs...
February 15, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29442558/progression-of-convulsive-and-nonconvulsive-seizures-during-epileptogenesis-after-pilocarpine-induced-status-epilepticus
#3
Zachariah Z Smith, Alexander M Benison, Florencia M Bercum, F Edward Dudek, Daniel S Barth
Although convulsive seizures occurring during pilocarpine-induced epileptogenesis have received considerable attention, nonconvulsive seizures have not been closely examined, even though they may reflect the earliest signs of epileptogenesis and potentially guide research on antiepileptogenic interventions. The definition of nonconvulsive seizures based on brain electrical activity alone has been controversial. Here, we define and quantify electrographic properties of convulsive and nonconvulsive seizures in the context of the acquired epileptogenesis that occurs after pilocarpine-induced status epilepticus (SE)...
February 14, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29432568/cellulite-a-surgical-treatment-approach
#4
Carlos Oscar Uebel, Pedro Salomao Piccinini, Alessandra Martinelli, Daniela Feijó Aguiar, Renato Franz Matta Ramos
Background: Cellulite is one of the most common skin and subcutaneous tissue conditions, affecting predominantly the thighs and hips in post-adolescent women. Its etiology is not well defined, and multiple available treatments show variable efficacy. Objective: To describe a technique for treatment of cellulite of the gluteal region, thighs, and hips through superficial liposuction utilizing a special cannula, combined with subcutaneous autologous fat grafting. Methods: A retrospective review was performed of patients treated over 26 years at the Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil...
February 8, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29432506/eating-habits-and-nutritional-status-of-patients-with-affective-disorders-and-schizophrenia
#5
Ewa Stefańska, Magdalena Lech, Agnieszka Wendołowicz, Beata Konarzewska, Napoleon Waszkiewicz, Lucyna Ostrowska
OBJECTIVES: The aim of the study was to assess the nutritional value of the food intake in the group of men and women suffering from recurrent affective disorders and schizophrenia, and also to determine the relation between selected nutritional parameters with anthropometric indices defining the nutritional status of the subjects. METHODS: 219 persons participated in the study (61 patients with recurrent depressive disorders, 60 patients with schizophrenia and 98 healthy volunteers)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29431910/lipomatoses
#6
Philipp Al Ghazal, Lisa-Lena Grönemeyer, Michael P Schön
Lipomatoses are benign proliferations of adipose tissue, often with typical distribution patterns, which usually occur without clear causes. In contrast to circumscribed lipomas, they develop diffusely and symmetrically and are not surrounded by a fibrous pseudocapsule. The most common form is benign symmetric lipomatosis (BSL; Launois-Bensaude syndrome), of which four types are distinguished based on the distribution pattern of hyperplastic adipose tissue. The etiology and pathogenesis of the disease are still largely unknown, although some forms appear to have a hereditary basis or to be associated with increased alcohol consumption...
February 12, 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29428124/bipolar-disorder-and-heart-transplantation-a-case-report
#7
Ana María Ramírez-Giraldo, Diana Restrepo
INTRODUCTION: Bipolar disorder is a chronic and recurrent mood disease that includes symptoms that fluctuate from euphoria to depression. As a mood disorder, itis one of the main contraindications for transplantation procedures. The case is presented of a patient with bipolar disorder who had a heart transplant after a cardiac arrest. Heart transplantation is the treatment of choice in patients with heart failure and arrhythmias that do not respond to conventional treatment. METHODS: Case report and narrative review of literature...
January 2018: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29426606/symptomatic-and-functional-recovery-from-major-depressive-disorder-in-the-ibadan-study-of-ageing
#8
Akin Ojagbemi, Taiwo Abiona, Zhehui Luo, Oye Gureje
OBJECTIVES: Very little is known about the association between symptomatic and functional recovery from late-life major depressive disorder (MDD) in sub-Saharan Africa. We investigated factors associated with sustained symptomatic remission (SR) from MDD and the 5-year trajectory of post-MDD physical functioning. DESIGN: 5-year prospective study with three follow-up waves in 2007, 2008, and 2009. SETTING/PARTICIPANTS: Household multistage probability sample of 2,149 Nigerians who were aged 65 years or older...
January 4, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29421266/neural-correlates-of-working-memory-in-first-episode-and-recurrent-depression-an-fmri-study
#9
Dilara Yüksel, Bruno Dietsche, Carsten Konrad, Udo Dannlowski, Tilo Kircher, Axel Krug
BACKGROUND: Patients suffering from major depressive disorder (MDD) show deficits in working memory (WM) performance accompanied by bilateral fronto-parietal signal changes. It is unclear whether patients with a first depressive episode (FDE) exhibit the same BOLD signal changes as patients with recurrent depressive episodes (RDE). METHODS: We investigated seventy-four MDD inpatients (48 RDE, 26 FDE) and 74 healthy control (HC) subjects performing an n-back WM task (0-back, 2-back, 3-back condition) in a 3T-fMRI...
February 5, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29417228/comparison-of-long-term-clinical-outcomes-between-endoscopic-and-surgical-resection-for-early-stage-adenocarcinoma-of-the-esophagogastric-junction
#10
Hyun Ju Kim, Hyunsoo Chung, Sung Kwan Shin, Hyoung-Il Kim, Jun Chul Park, Sang Kil Lee, Woo Jin Hyung, Yong Chan Lee, Sung Hoon Noh
BACKGROUND: The aim of this study was to analyze long-term clinical and oncologic outcomes in patients with early-stage adenocarcinoma of the esophagogastric junction (AEG) managed with either endoscopic resection (ER) or surgery. METHODS: The inclusion criteria were AEG, meeting classic or expanded indications for ER of early gastric cancer, and complete resection. A total of 66 patients with Siewert type II AEG were included (ER group, n = 38; vs. surgery group, n = 28)...
February 7, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29412114/caveolin-1-in-stroke-neuropathology-and-neuroprotection-a-novel-molecular-therapeutic-target-for-ischemic-related-injury
#11
Shanshan Wang, Brian P Head
Cardiovascular disease and associated cerebral stroke are a global epidemic attributed to genetic and epigenetic factors, such as diet, life style and an increasingly sedentary existence due to technological advances in both the developing and developed world. There are approximately 5.9 million stroke-related deaths worldwide annually. Current epidemiological data indicate that nearly 16.9 million people worldwide suffer a new or recurrent stroke yearly. In 2014 alone, 2.4% of adults in the United States (U...
February 5, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29408454/effect-of-urethroplasty-on-anxiety-and-depression
#12
Jared P Schober, Kristian D Stensland, Benjamin N Breyer, Bradley A Erickson, Jeremy B Myers, Bryan B Voelzke, Sean P Elliott, Jill C Buckley, Alex J Vanni
INTRODUCTION: and Objective: Anxiety and depression (AD) in patients with urethral stricture disease (USD) and the impact of urethroplasty on mental health has never been explored. We hypothesized that patients with USD will have higher than normal AD levels and urethroplasty would improve mental health. METHODS: Patients undergoing anterior urethroplasty were retrospectively reviewed from a multi-institutional reconstructive urology database. Pre- and postoperative evaluation of AD and overall health was recorded using the validated EQ-5D-3L Questionnaire, while sexual function was evaluated with the International Index of Erectile Function (IIEF) and Men's Sexual Health Questionnaire (MSHQ)...
February 3, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29407668/diagnosed-dementia-and-the-risk-of-motor-vehicle-crash-among-older-drivers
#13
Laura A Fraade-Blanar, Ryan N Hansen, Kwun Chuen G Chan, Jeanne M Sears, Hilaire J Thompson, Paul K Crane, Beth E Ebel
Older adults are an active and growing segment of drivers in the United States. We compared the risk of motor vehicle crash among older licensed drivers diagnosed with dementia to crash risk among older licensed drivers without diagnosis of dementia. This retrospective cohort study used data from Group Health (GH), a Washington State health maintenance organization. Research participants were members of GH, aged 65-79 during the study who lived in Washington State from 1999-2009. Participant health records were linked with police-reported crash and licensure records...
January 25, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29397079/electroencephalography-source-functional-connectivity-reveals-abnormal-high-frequency-communication-among-large-scale-functional-networks-in-depression
#14
Alexis E Whitton, Stephanie Deccy, Manon L Ironside, Poornima Kumar, Miranda Beltzer, Diego A Pizzagalli
BACKGROUND: Functional magnetic resonance imaging studies of resting-state functional connectivity have shown that major depressive disorder (MDD) is characterized by increased connectivity within the default mode network (DMN) and between the DMN and the frontoparietal network (FPN). However, much remains unknown about abnormalities in higher frequency (>1 Hz) synchronization. Findings of abnormal synchronization in specific frequencies would contribute to a better understanding of the potential neurophysiological origins of disrupted functional connectivity in MDD...
January 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29391394/testing-frameworks-for-personalizing-bipolar-disorder
#15
Amy L Cochran, André Schultz, Melvin G McInnis, Daniel B Forger
The hallmark of bipolar disorder is a clinical course of recurrent manic and depressive symptoms of varying severity and duration. Mathematical modeling of bipolar disorder holds the promise of an ability to personalize diagnoses, to predict future mood episodes, to directly compare diverse datasets, and to link basic mechanisms to behavioral data. Several modeling frameworks have been proposed for bipolar disorder, which represent competing hypothesis about the basic framework of the disorder. Here, we test these hypotheses with self-report assessments of mania and depression symptoms from 178 bipolar patients followed prospectively for 4 or more years...
February 2, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29388894/coping-action-patterns-as-mechanisms-of-change-across-psychotherapies-three-case-examples-of-personality-disorders-with-recurrent-major-depression
#16
Claire J Starrs, J Christopher Perry
Maladaptive coping has been shown to be related to increased symptoms of distress and lower levels of well-being, whereas the use of adaptive coping has been shown to diminish distress and improve functioning. This suggests that change in coping may constitute a significant mechanism of change in psychotherapy. Utilizing a novel observer-rating method for assessing coping, the current report examined changes in overall coping functioning (OCF) in three participants with diverse personality disorders who were undergoing two different types of psychotherapy (cognitive-behavioral therapy and dynamic therapy) for recurrent major depression...
January 2018: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29382674/study-protocol-for-a-randomised-controlled-platform-trial-estimating-the-effect-of-autobiographical-memory-flexibility-training-memflex-on-relapse-of-recurrent-major-depressive-disorder
#17
Caitlin Hitchcock, Siobhan Gormley, Cliodhna O'Leary, Evangeline Rodrigues, Isobel Wright, Kirsty Griffiths, Julia Gillard, Peter Watson, Emily Hammond, Aliza Werner-Seidler, Tim Dalgleish
INTRODUCTION: Major depressive disorder (MDD) is a chronic condition. Although current treatment approaches are effective in reducing acute depressive symptoms, rates of relapse are high. Chronic and inflexible retrieval of autobiographical memories, and in particular a bias towards negative and overgeneral memories, is a reliable predictor of relapse. This randomised controlled single-blind trial will determine whether a therapist-guided self-help intervention to ameliorate autobiographical memory biases using Memory Flexibility training (MemFlex) will increase the experience of depression-free days, relative to a psychoeducation control condition, in the 12 months following intervention...
January 29, 2018: BMJ Open
https://www.readbyqxmd.com/read/29382584/incidence-of-diabetic-foot-ulcer-in-japanese-patients-with-type-2-diabetes-mellitus-the-fukuoka-diabetes-registry
#18
Masanori Iwase, Hiroki Fujii, Udai Nakamura, Toshiaki Ohkuma, Hitoshi Ide, Tamaki Jodai-Kitamura, Akiko Sumi, Yuji Komorita, Masahito Yoshinari, Takanari Kitazono
AIMS: Although diabetic foot ulcer (DFU) is a serious diabetic complication, there have been no large-scale epidemiological studies of DFU in Japan. We prospectively investigated the incidences of DFU and limb amputation, the risk for developing DFU, and mortality in Japanese patients with type 2 diabetes. METHODS: We followed 4,870 participants (mean age, 65 years) with type 2 diabetes attending an outpatient diabetes clinic for a median of 5.3 years (follow-up rate, 97...
January 27, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29379563/the-relationship-of-parental-pain-catastrophizing-with-parents-reports-of-children-s-anxiety-depression-and-headache-severity
#19
Ghazale Akbarzadeh, Hojjat Daniali, Mohsen Javdzadh, Line Caes, Seyran Ranjbar, Mojtaba Habibi
Objective: Parental pain catastrophizing is a construct recognized to have a significant impact on experience of pain in both children and parents. This research aimed to investigate the probable relationship of parental pain catastrophizing with the parent's reports of children's anxiety, depression and headache severity amongst Iranian parents of children with chronic or recurrent headache. Materials & Methods: This study was conducted in 2015-16, in two pediatric neurological centers located in Tehran, Iran; with a convenience sampling method and 212 parents (120 mothers and 92 fathers) of 132 children with a chronic or recurrent headache (migraine and tension-type)...
2018: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29372545/prospects-of-cannabidiol-for-easing-status-epilepticus-induced-epileptogenesis-and-related-comorbidities
#20
REVIEW
Dinesh Upadhya, Olagide W Castro, Raghavendra Upadhya, Ashok K Shetty
The hippocampus is one of the most susceptible regions in the brain to be distraught with status epilepticus (SE) induced injury. SE can occur from numerous causes and is more frequent in children and the elderly population. Administration of a combination of antiepileptic drugs can abolish acute seizures in most instances of SE but cannot prevent the morbidity typically seen in survivors of SE such as cognitive and mood impairments and spontaneous recurrent seizures. This is primarily due to the inefficiency of antiepileptic drugs to modify the evolution of SE-induced initial precipitating injury into a series of epileptogenic changes followed by a state of chronic epilepsy...
January 25, 2018: Molecular Neurobiology
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