keyword
https://read.qxmd.com/read/38536160/validation-of-thermal-imaging-and-the-alt-70-prediction-model-to-differentiate-cellulitis-from-pseudocellulitis
#1
JOURNAL ARTICLE
Michael S Pulia, Rebecca J Schwei, Roxana Alexandridis, Michael R Lasarev, Edward Harwick, Robert Glinert, Ambar Haleem, Jamie Hess, Thomas D Keenan, Joseph A McBride, Robert Redwood
IMPORTANCE: Cellulitis is misdiagnosed in up to 30% of cases due to mimic conditions termed pseudocellulitis. The resulting overuse of antibiotics is a threat to patient safety and public health. Surface thermal imaging and the ALT-70 (asymmetry, leukocytosis, tachycardia, and age ≥70 years) prediction model have been proposed as tools to help differentiate cellulitis from pseudocellulitis. OBJECTIVES: To validate differences in skin surface temperatures between patients with cellulitis and patients with pseudocellulitis, assess the optimal temperature measure and cut point for differentiating cellulitis from pseudocellulitis, and compare the performance of skin surface temperature and the ALT-70 prediction model in differentiating cellulitis from pseudocellulitis...
March 27, 2024: JAMA Dermatology
https://read.qxmd.com/read/38532370/elucidating-the-need-for-prostate-cancer-risk-calculators-in-conjunction-with-mpmri-in-initial-risk-assessment-before-prostate-biopsy-at-a-tertiary-prostate-cancer-center
#2
JOURNAL ARTICLE
Philipp Krausewitz, Thomas Büttner, Marthe von Danwitz, Richard Weiten, Alexander Cox, Niklas Klümper, Johannes Stein, Julian Luetkens, Glen Kristiansen, Manuel Ritter, Jörg Ellinger
OBJECTIVE: Utilizing personalized risk assessment for clinically significant prostate cancer (csPCa) incorporating multiparametric magnetic resonance imaging (mpMRI) reduces biopsies and overdiagnosis. We validated both multi- and univariate risk models in biopsy-naïve men, with and without the inclusion of mpMRI data for csPCa detection. METHODS: N = 565 men underwent mpMRI-targeted prostate biopsy, and the diagnostic performance of risk calculators (RCs), mpMRI alone, and clinical measures were compared using receiver operating characteristic curve (ROC) analysis and decision curve analysis (DCA)...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38517462/cancer-screening-with-multicancer-detection-tests-a-translational-science-review
#3
REVIEW
Wendy S Rubinstein, Christos Patriotis, Anthony Dickherber, Paul K J Han, Hormuzd A Katki, Elyse LeeVan, Paul F Pinsky, Philip C Prorok, Amanda L Skarlupka, Sarah M Temkin, Philip E Castle, Lori M Minasian
Multicancer detection (MCD) tests use a single, easily obtainable biospecimen, such as blood, to screen for more than one cancer concurrently. MCD tests can potentially be used to improve early cancer detection, including cancers that currently lack effective screening methods. However, these tests have unknown and unquantified benefits and harms. MCD tests differ from conventional cancer screening tests in that the organ responsible for a positive test is unknown, and a broad diagnostic workup may be necessary to confirm the location and type of underlying cancer...
March 22, 2024: CA: a Cancer Journal for Clinicians
https://read.qxmd.com/read/38517400/letter-to-the-editor-routine-mri-among-patients-with-a-suspected-scaphoid-fracture-risks-overdiagnosis
#4
JOURNAL ARTICLE
Joseph Bernstein
No abstract text is available yet for this article.
March 20, 2024: Clinical Orthopaedics and related Research
https://read.qxmd.com/read/38508616/enablers-and-barriers-to-a-quaternary-prevention-approach-a-qualitative-study-of-field-experts
#5
JOURNAL ARTICLE
Jessica Anneliese Otte, Maria Llargués Pou
OBJECTIVE: There is a growing concern about the sustainability of healthcare and the impacts of 'overuse' on patients and systems. Quaternary prevention (P4), a concept promoting the protection of patients from medical interventions in which harms outweigh benefits, is well positioned to stimulate reflection and inspire solutions, yet has not been widely adopted. We sought to identify enablers and barriers to a P4 approach, according to field experts and advocates in one health system...
March 19, 2024: BMJ Open
https://read.qxmd.com/read/38505883/artificial-intelligence-in-bone-metastasis-imaging-recent-progresses-from-diagnosis-to-treatment-a-narrative-review
#6
JOURNAL ARTICLE
Elena Caloro, Giulia Gnocchi, Cettina Quarrella, Maurizio Ce, Gianpaolo Carrafiello, Michaela Cellina
The introduction of artificial intelligence (AI) represents an actual revolution in the radiological field, including bone lesion imaging. Bone lesions are often detected both in healthy and oncological patients and the differential diagnosis can be challenging but decisive, because it affects the diagnostic and therapeutic process, especially in case of metastases. Several studies have already demonstrated how the integration of AI-based tools in the current clinical workflow could bring benefits to patients and to healthcare workers...
2024: Critical Reviews in Oncogenesis
https://read.qxmd.com/read/38501072/thyroid-ultrasound-appropriateness-identification-through-natural-language-processing-of-electronic-health-records
#7
JOURNAL ARTICLE
Cristian Soto Jacome, Danny Segura Torres, Jungwei W Fan, Ricardo Loor-Torres, Mayra Duran, Misk Al Zahidy, Esteban Cabezas, Mariana Borras-Osorio, David Toro-Tobon, Yuqi Wu, Yonghui Wu, Naykky Singh Ospina, Juan P Brito
OBJECTIVE: To address thyroid cancer overdiagnosis, we aim to develop a natural language processing (NLP) algorithm to determine the appropriateness of thyroid ultrasounds (TUS). PATIENTS AND METHODS: Between 2017 and 2021, we identified 18,000 TUS patients at Mayo Clinic and selected 628 for chart review to create a ground truth dataset based on consensus. We developed a rule-based NLP pipeline to identify TUS as appropriate TUS (aTUS) or inappropriate TUS (iTUS) using patients' clinical notes and additional meta information...
March 2024: Mayo Clin Proc Digit Health
https://read.qxmd.com/read/38498895/estimating-breast-cancer-overdiagnosis-after-screening-mammography-among-older-women-in-the-united-states
#8
JOURNAL ARTICLE
Per-Henrik Zahl, Karsten J Jørgensen
No abstract text is available yet for this article.
March 2024: Annals of Internal Medicine
https://read.qxmd.com/read/38498894/estimating-breast-cancer-overdiagnosis-after-screening-mammography-among-older-women-in-the-united-states
#9
JOURNAL ARTICLE
Ilana B Richman, Cary P Gross
No abstract text is available yet for this article.
March 2024: Annals of Internal Medicine
https://read.qxmd.com/read/38498875/development-and-evaluation-of-messages-for-reducing-overscreening-of-breast-cancer-in-older-women
#10
JOURNAL ARTICLE
Nancy L Schoenborn, Sarah E Gollust, Mara A Schonberg, Craig E Pollack, Cynthia M Boyd, Qian-Li Xue, Rebekah H Nagler
BACKGROUND: Many older women are screened for breast cancer beyond guideline-recommended thresholds. One contributor is pro-screening messaging from health care professionals, media, and family/friends. In this project, we developed and evaluated messages for reducing overscreening in older women. METHODS: We surveyed women ages 65+ who were members of a nationally representative online panel. We constructed 8 messages describing reasons to consider stopping mammograms, including guideline recommendations, false positives, overdiagnosis, and diminishing benefits from screening due to competing risks...
March 12, 2024: Medical Care
https://read.qxmd.com/read/38494379/does-overgrading-on-targeted-biopsy-of-magnetic-resonance-imaging-visible-lesions-in-prostate-cancer-lead-to-overtreatment
#11
JOURNAL ARTICLE
Michael Baboudjian, Romain Diamand, Alessandro Uleri, Jean-Baptiste Beauval, Alae Touzani, Jean-Baptiste Roche, Vito Lacetera, Thierry Roumeguère, Giuseppe Simone, Daniel Benamran, Alexandre Fourcade, Bastien Gondran-Tellier, Gaelle Fiard, Alexandre Peltier, Guillaume Ploussard
BACKGROUND AND OBJECTIVE: Targeted biopsy of the index prostate cancer (PCa) lesion on multiparametric magnetic resonance imaging (MRI) is effective in reducing the risk of overdiagnosis of indolent PCa. However, it remains to be determined whether MRI-targeted biopsy can lead to a stage shift via overgrading of the index lesion by focusing only on the highest-grade component, and to a subsequent risk of overtreatment. Our aim was to assess whether overgrading on MRI-targeted biopsy may lead to overtreatment, using radical prostatectomy (RP) specimens as the reference standard...
March 16, 2024: European Urology
https://read.qxmd.com/read/38493159/screening-for-lung-cancer-with-computed-tomography-protocol-for-systematic-reviews-for-the-canadian-task-force-on-preventive-health-care
#12
JOURNAL ARTICLE
Jennifer Pillay, Sholeh Rahman, Scott Klarenbach, Donna L Reynolds, Laure A Tessier, Guylène Thériault, Nav Persaud, Christian Finley, Natasha Leighl, Matthew D F McInnes, Chantelle Garritty, Gregory Traversy, Maria Tan, Lisa Hartling
PURPOSE: Lung cancer is the leading cause of cancer deaths in Canada, and because early cancers are often asymptomatic screening aims to prevent mortality by detecting cancer earlier when treatment is more likely to be curative. These reviews will inform updated recommendations by the Canadian Task Force on Preventive Health Care on screening for lung cancer. METHODS: We will update the review on the benefits and harms of screening with CT conducted for the task force in 2015 and perform de novo reviews on the comparative effects between (i) trial-based selection criteria and use of risk prediction models and (ii) trial-based nodule classification and different nodule classification systems and on patients' values and preferences...
March 16, 2024: Systematic Reviews
https://read.qxmd.com/read/38492551/on-punctate-white-matter-lesions-in-preterm-infants-is-ultrasound-diagnosis-feasible
#13
JOURNAL ARTICLE
Philippe Quétin, Nicolas Leboucq, Charlotte Boyer, Françoise Crozier, Philippe Delachartre, Marilyne Grinand, Philippe Masson, Olivier Claris
OBJECTIVES: To observe hyperechoic nodular or punctate white matter lesions (HNPL) in a population of preterm infants using routine cranial ultrasound (cUS), to describe the characteristics of HNPL, and to compare them with punctate white matter lesions (PWML) detected in magnetic resonance imaging (MRI). DESIGN: Retrospective observational single-center cohort study. SETTING: Level 2B neonatal unit in France. PATIENTS: 307 infants born <33 weeks gestation undergoing routine cUS with a total of 961 cUS performed...
March 1, 2024: European Journal of Paediatric Neurology: EJPN
https://read.qxmd.com/read/38492083/the-contradictive-findings-between-ultrasound-hysteroscopy-and-cytokines-in-women-with-nonhormonal-iuds-suffering-from-menorrhagia-a-prospective-study
#14
JOURNAL ARTICLE
Hadel Watad, Udi Ifrach, David Stockheim, Vered Yulzari, Orly C Meron, Miri Blank, Benjamin Sredni, Boaz Weisz, Shlomo B Cohen
PURPOSE: The objective of this study is to assess the correlation between bleeding irregularities and the accurate placement of the intrauterine device (IUD) device in the uterine cavity, determined through transvaginal ultrasonography and hysteroscopy. In addition, the study aims to examine the cytokine profile in the uterine cavity and serum of patients experiencing bleeding irregularities after the insertion of nonhormonal IUDs. METHODS: A prospective cohort study was conducted at a single tertiary medical center, wherein patients experiencing intermenstrual bleeding and spotting after the insertion of nonhormonal IUDs were enrolled...
March 16, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38490856/prostate-cancers-in-the-prostate-specific-antigen-interval-of-1-8-3-ng-ml-results-from-the-g%C3%A3-teborg-2-prostate-cancer-screening-trial
#15
JOURNAL ARTICLE
Fredrik Möller, Marianne Månsson, Jonas Wallström, Mikael Hellström, Jonas Hugosson, Rebecka Arnsrud Godtman
BACKGROUND: Magnetic resonance imaging (MRI) and targeted biopsies reduce overdiagnosis of prostate cancer (PC). It is uncertain how this strategy performs for low prostate-specific antigen (PSA) levels. OBJECTIVE: To investigate the Prostate Imaging Reporting and Data System (PI-RADS) distribution, frequency, and characteristics of screen-detected PC with PSA of 1.8-<3 ng/ml and 3-<10 ng/ml. DESIGN, SETTING, AND PARTICIPANTS: In the population-based Göteborg-2 screening study, 17974 men choose to participate by having a PSA test (2015-2020)...
March 14, 2024: European Urology
https://read.qxmd.com/read/38485207/teaching-to-address-overdiagnosis
#16
JOURNAL ARTICLE
Natalie Edmiston, Iman Hegazi
No abstract text is available yet for this article.
March 14, 2024: BMJ Evidence-Based Medicine
https://read.qxmd.com/read/38480076/evaluating-efficiency-and-adherence-in-asian-lung-cancer-screening-comparing-self-paid-and-clinical-study-approaches-in-taiwan
#17
JOURNAL ARTICLE
Yun-Ju Wu, En-Kuei Tang, Fu-Zong Wu
RATIONALE AND OBJECTIVES: This study aimed to assess how different screening methods, specifically self-paid screening versus participation in clinical studies, affect screening efficiency and adherence in a real-world Asian lung cancer screening population. MATERIALS AND METHODS: This study collected 4166 participants from our hospital imaging database who underwent baseline low-dose computed tomography (LDCT) between January 2014 and August 2021. Adherence status was determined by counting CT scans, with one check indicating non-adherence and two or more checks indicating adherence...
March 12, 2024: Academic Radiology
https://read.qxmd.com/read/38471462/cancer-related-cognitive-dysfunction-a-narrative-review-for-clinical-practice
#18
REVIEW
Oliver Rick, Alexandra Gerhardt, Georgia Schilling
BACKGROUND: Cancer-related cognitive dysfunction (CRCD) is a major functional disorder in patients with cancer. This central nervous dysfunction is found in up to 60 % of patients after tumour therapy, often significantly limits the quality of life and significantly impedes participation in working life. For this reason, diagnosis and treatment of CRCD is of central importance. This narrative review is intended to provide an overview and support for practical clinical care with regard to diagnostics and therapeutic options...
March 12, 2024: Oncology Research and Treatment
https://read.qxmd.com/read/38469728/evolution-of-european-prostate-cancer-screening-protocols-and-summary-of-ongoing-trials
#19
REVIEW
Meike J van Harten, Monique J Roobol, Pim J van Leeuwen, Peter-Paul M Willemse, Roderick C N van den Bergh
Population-based organised repeated screening for prostate cancer has been found to reduce disease-specific mortality, but with substantial overdiagnosis leading to overtreatment. Although only very few countries have implemented a screening programme on a national level, individual prostate-specific antigen (PSA) testing is common. This opportunistic testing may have little favourable impact, while stressing the side-effects. The classic early detection protocols as were state-of-the-art in the 1990s applied a PSA and digital rectal examination threshold for sextant systematic prostate biopsy, with a fixed interval for re-testing, and limited indication for expectant management...
March 12, 2024: BJU International
https://read.qxmd.com/read/38462871/diagnostic-accuracy-of-jes-classification-for-prediction-of-invasion-depth-in-superficial-esophageal-squamous-carcinoma-meta-analysis
#20
JOURNAL ARTICLE
Dou Fu, Hui Zhao, Wenquan Lan, Yuanfa Li
Prediction of the depth of invasion in superficial oesophageal squamous carcinoma (SESC) is an important factor for choosing the treatment. Recently, the Japan Esophageal Society (JES) designed a magnifying endoscopy classification based on the Inoue and Arima classifications. The aim of this study was to conduct a meta-analysis of the published literature on JES classification. Meta-Disc version 1.4, Review Manager 5.4 as well as stata 14.0 were used. The analysis combined sensitivity and specificity with the respective 95% CI, to draw a summary receiver operating characteristic curve (SROC), and estimated the area under curve (AUC) for overdiagnosis and underdiagnosis for each type B...
March 2024: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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