Laura Taguchi, Nathalia M Pinheiro, Clarice R Olivo, Alessandra Choqueta-Toledo, Simone S Grecco, Fernanda D T Q S Lopes, Luciana C Caperuto, Mílton A Martins, Iolanda F L C Tiberio, Niels O Câmara, João Henrique G Lago, Carla M Prado
BACKGROUND: Pulmonary emphysema is characterized by irreversible airflow obstruction, inflammation, oxidative stress imbalance and lung remodeling, resulting in reduced lung function and a lower quality of life. Flavonoids are plant compounds with potential anti-inflammatory and antioxidant effects that have been used in folk medicine. Our aim was to determine whether treatment with sakuranetin, a flavonoid extracted from the aerial parts of Baccharis retusa, interferes with the development of lung emphysema...
June 30, 2015: Respiratory Research