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Uterine fibroids

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https://www.readbyqxmd.com/read/28922305/mayer-rokitansky-k%C3%A3-ster-hauser-syndrome-with-bilateral-ovarian-sertoli-cell-tumors-review-of-the-literature-and-report-of-a-rare-case
#1
Alexander L Juusela, Ilana Naghi, Suresh Thani
BACKGROUND: Patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome are infertile secondary to hypoplasia or complete agenesis of the uterus, yet they remain at risk of primary neoplasms of the ovaries because embryologically the uterus and ovaries develop via separate mechanisms. CASE: A 72-year-old nulliparous woman with a history of primary amenorrhea underwent an exploratory laparotomy for a suspected uterine fibroid. In addition to the pelvic mass, the patient was found to have findings consistent with MRKH syndrome...
September 15, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28919823/updated-approaches-for-management-of-uterine-fibroids
#2
REVIEW
Aymara Mas, Marta Tarazona, Joana Dasí Carrasco, Gloria Estaca, Ignacio Cristóbal, Javier Monleón
Uterine anatomy and uterine fibroids (UFs) characteristics have been classically considered as almost a unique issue in gynecology and reproductive medicine. Nowadays, the management of UF pathology is undergoing an important evolution, with the patient's quality of life being the most important aspect to consider. Accordingly, surgical techniques and aggressive treatments are reserved for only those cases with heavy symptomatology, while the clinical diagnostic based on size and number of UFs remains in a second plane in these situations...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28919793/burden-of-uterine-fibroids-in-italy-epidemiology-treatment-outcomes-and-consumption-of-health-care-resources-in-more-than-5-000-women
#3
Marco Chiumente, Mauro De Rosa, Andrea Messori, Enrica Maria Proli
BACKGROUND AND PURPOSE: Epidemiological studies on uterine fibroids (UFs) are mostly based on surveys or analyses of small samples of patients. In 50% of women, the quality of life is worsened by disease-related symptoms; furthermore, treatments imply a remarkable health care cost. The aim of this observational study was to analyze a large sample of Italian patients with UFs and to assess the epidemiology, the appropriateness of treatments, and the consumption of disease-related resources...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28904795/cervical-superficial-myofibroblastoma-case-report-and-review-of-the-literature
#4
Mohamed Abdelaziz, Noura Eziba, Suash Sharma, Daniel Kleven, Ayman Al-Hendy
Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28900897/ulipristal-acetate-a-review-in-symptomatic-uterine-fibroids
#5
Karly P Garnock-Jones, Sean T Duggan
Oral ulipristal acetate (Esmya(®); Fibristal(®)), a synthetic selective progesterone receptor modulator, is the first selective progesterone modulator to be approved for the treatment of uterine fibroids. It was initially approved for the preoperative treatment of moderate to severe uterine fibroid symptoms in women of reproductive age. Recently, the indication was extended in the EU to include the intermittent treatment of moderate to severe uterine fibroid symptoms. This narrative review summarizes pharmacological, efficacy and tolerability data relevant to the preoperative and intermittent use of ulipristal acetate in patients with symptomatic uterine fibroids...
September 12, 2017: Drugs
https://www.readbyqxmd.com/read/28892210/myoma-and-myomectomy-poor-evidence-concern-in-pregnancy
#6
REVIEW
Giusi Natalia Milazzo, Angelica Catalano, Valentina Badia, Maddalena Mallozzi, Donatella Caserta
AIM: Summarize the results of the many, but often underpowered, studies on pregnancy complicated by myoma or myomectomy. METHODS: Survey of the electronic PubMed database for the last two decades was conducted. We selected reviews, meta-analyses, case series, case reports, clinical studies only with statistical analysis, and guidelines from scientific societies. RESULTS: Delaying childbearing leads to an increased incidence of pregnancy complicated by fibroids or previous myomectomy...
September 11, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28890674/treating-symptomatic-uterine-fibroids-with-myomectomy-current-practice-and-views-of-uk-consultants
#7
R Fusun Sirkeci, Anna Maria Belli, Isaac T Manyonda
BACKGROUND: The demand for uterus-sparing treatments is increasing as more women postpone childbirth to their 30-40s, when fibroids are more symptomatic. With an increasing choice of treatment options and changing care-provider profiles, now is an opportune time to survey current practices and opinions. Using a 25-stem questionnaire, a web-based survey was used to capture the practices and opinions of UK consultant gynecologists on the treatment of symptomatic fibroids, including the types of procedure most frequently used, methods used to reduce blood loss, and awareness and acceptability of treatment options, and to assess the impact of gender and experience of the treating gynecologist...
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/28887670/comparison-of-two-endovascular-steerable-robotic-catheters-for-percutaneous-robot-assisted-fibroid-embolization
#8
C Del Giudice, O Pellerin, M Nouri Neville, G Amouyal, I Fitton, C Leré-Déan, M Sapoval
PURPOSE: To compare outcomes of percutaneous robot-assisted uterine fibroid embolization (UFE) using two different endovascular robotic catheters. METHODS: Twenty-one patients with a symptomatic uterine fibroid were prospectively enrolled in a single-center study to be treated with a percutaneous robot-assisted embolization using the Magellan system. Fourteen patients were treated using a first generation steerable robotic catheter, version 1.0 (group 1), and seven were treated using the new version 1...
September 8, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28885274/fertility-preserved-hysteroscopic-approach-for-the-treatment-of-stage-ia-endometrioid-carcinoma
#9
Fangfang Wang, Aijun Yu, Haichao Xu, Xiaojing Zhang, Li Li, Hanmei Lou, Hua Yu, Jun Lin
OBJECTIVE: This study aims to explore the feasibility of a hysteroscopic procedure combined with progestin therapy in young patients with stage Ia endometrioid carcinoma (EC) to avoid sterilization. MATERIALS AND METHODS: Eleven young women with stage Ia EC (International Federation of Gynecology and Obstetrics grade 1) who were treated with a hysteroscopic approach combined with progestin from July 2004 to June 2016 were retrospectively analyzed and followed up to monitor their general recovery and pregnancy outcome...
September 6, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28883630/a-clinical-investigation-treating-different-types-of-fibroids-identified-by-mri-t2wi-imaging-with-ultrasound-guided-high-intensity-focused-ultrasound
#10
Wen-Peng Zhao, Jing Zhang, Zhi-Yu Han, Jin-Peng Yao, Xiang Zhou, Ping Liang
Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified by T2-weighted magnetic resonance imaging (MRI-T2WI). Based on MRI-T2WI signal intensities, uterine fibroids were classified as three types: hypointensive (52 cases), isointensive (64 cases) and hyperintensive (56 cases)...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28876143/anti-m%C3%A3-llerian-hormone-levels-before-and-after-uterine-artery-embolization
#11
Bruce McLucas, William D Voorhees, Scott A Snyder
OBJECTIVE: To determine the effects of uterine artery embolization (UAE) on ovarian reserve as measured by Anti-Müllerian hormone (AMH) levels. MATERIAL AND METHODS: Non-randomized, observational study of 89 women 23-40 years of age who received UAE. Control hormone levels were measured prior to UAE and the first post-embolization measurement was taken at various times post-procedure (mean = 190 ± 229 days). RESULTS: Historical work verified by our earlier work has shown that AMH levels decline with age...
September 6, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28875276/epigenetic-and-genetic-landscape-of-uterine-leiomyomas-a-current-view-over-a-common-gynecological-disease
#12
Antonio Simone Laganà, Daniele Vergara, Alessandro Favilli, Valentina Lucia La Rosa, Andrea Tinelli, Sandro Gerli, Marco Noventa, Amerigo Vitagliano, Onofrio Triolo, Agnese Maria Chiara Rapisarda, Salvatore Giovanni Vitale
PURPOSE: Despite the numerous studies on the factors involved in the genesis and growth of uterine leiomyomas, the pathogenesis of these tumors remains unknown. Intrinsic abnormalities of the myometrium, abnormal myometrial receptors for estrogen, and hormonal changes or altered responses to ischemic damage during the menstrual period may be responsible for the initiation of (epi)genetic changes found in these tumors. Considering these elements, we aimed to offer an overview about epigenetic and genetic landscape of uterine leiomyomas...
September 5, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28871011/economic-impact-of-ulipristal-acetate-on-surgical-procedures-for-uterine-fibroids-in-france
#13
Hervé Fernandez, Olivier Jourdain, Vincent Villefranque, Matthieu Lehmann, Antoine Lafuma, Matthieu Trancart
OBJECTIVE: To assess the budget impact of using ulipristal acetate (UPA) 5 mg to treat women with uterine fibroids (UF) causing moderate to severe symptoms. DESIGN: We modelled trends in the number of surgical procedures for symptomatic UF, with and without the use of UPA for preoperative or intermittent treatment and assessed the budget impact of UPA use from the French national healthcare insurance system perspective. SETTING: A French national hospital database (PMSI) that records admissions and relative procedures to public and private hospitals...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28867860/ayurvedic-management-of-recurrent-abortions-due-to-uterine-fibroid
#14
Shailendra Dadarao Katakdound
Uterine fibroids are present in 30-70% of women of reproductive age. Uterine fibroids distort the uterine cavity. Therefore there is consensus of a negative impact on both the clinical pregnancy and delivery rates.[2] In addition, studies have also reported an increased risk of spontaneous miscarriage with submucosal fibroids. In biomedicine, myomectomy is considered the treatment of choice and Assisted Reproductive Technology is advised to overcome infertility. In Hārita Saṃhitā treatment is given for recurrent abortion (Garbhasrāvī)...
January 2017: Ancient Science of Life
https://www.readbyqxmd.com/read/28866121/focus-on-uterine-fibroids-evolving-options-to-optimize-care
#15
Sukhbir Sony Singh, Erica E Marsh
No abstract text is available yet for this article.
September 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28866098/tissue-extraction-techniques-during-laparoscopic-uterine-surgery
#16
REVIEW
Nisse V Clark, Sarah L Cohen
Morcellation allows minimally invasive approaches to surgery even in the presence of large uteri or fibroids. Recent restrictions in the use of power morcellation as well as concern regarding the potential for morcellation to disseminate malignant tissue have initiated investigation and innovation to find safer methods. Current techniques for tissue extraction during uterine surgery with a focus on contained power morcellation and contained manual morcellation via minilaparotomy or colpotomy are reviewed herein...
August 30, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28863997/micronized-progesterone-pretreatment-affects-the-inflammatory-response-of-human-gestational-tissues-and-the-cervix-to-lipopolysaccharide-stimulation
#17
Tai-Ho Hung, Szu-Fu Chen, Chung-Pu Wu, Meng-Jen Li, Yi-Lin Yeh, T'sang-T'ang Hsieh
INTRODUCTION: Vaginal administration of micronized progesterone (utrogestan capsule, UG) reduces the risk of preterm birth (PTB) in asymptomatic women with a sonographic short cervix at mid-trimester or with a prior history of spontaneous PTB; however, its exact mechanisms remain unclear. We hypothesized that UG limits the inflammatory processes within the gestational tissues and the cervix. METHODS: Fetal membranes and villous tissues were obtained from normal term placentas from women with cesarean delivery before labor onset...
September 2017: Placenta
https://www.readbyqxmd.com/read/28856867/changes-in-anti-m%C3%A3-llerian-hormone-levels-as-a-biomarker-for-ovarian-reserve-after-ultrasound-guided-high-intensity-focused-ultrasound-treatment-of-adenomyosis-and-uterine-fibroid
#18
J-S Lee, G-Y Hong, K-H Lee, T-E Kim
OBJECTIVE: To assess the changes in antimüllerian hormone (AMH) levels after ablation for symptomatic uterine fibroids and adenomyosis using ultrasound-guided high-intensity focused ultrasound (USgHIFU). DESIGN: A prospective study. SETTING: Gynaecological department in multiple hospitals in South Korea. POPULATION: Patients with uterus fibroids and adenomyosis. METHODS: Seventy-nine women with symptomatic uterine fibroids and adenomyosis who met the inclusion criteria were enrolled in our study between January 2014 and December 2014...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28856864/pregnancy-outcomes-in-patients-with-uterine-fibroids-treated-with-ultrasound-guided-high-intensity-focused-ultrasound
#19
M Zou, L Chen, C Wu, C Hu, Y Xiong
OBJECTIVE: To investigate the effect of high-intensity focused ultrasound (HIFU) ablation for uterine fibroids on pregnancy. DESIGN: A retrospective observational study. SETTING: Department of Gynaecology in a single centre in China. POPULATION: Patients with uterine fibroids who wish to become pregnant. METHODS: Patients with uterine fibroids who wished become pregnant and have children, were treated using HIFU from April 2011 to March 2016 at Chongqing Haifu Hospital...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28856860/the-effect-of-exercise-on-high-intensity-focused-ultrasound-treatment-efficacy-in-uterine-fibroids-and-adenomyosis-a-retrospective-study
#20
X Huang, D Yu, M Zou, L Wang, H R Xing, Z Wang
OBJECTIVE: We conducted a retrospective study to evaluate whether exercise after high-intensity focused ultrasound (HIFU) treatment can improve the absorption of uterine fibroids and the relief of dysmenorrhea caused by adenomyosis. DESIGN: A retrospective study. SETTING: Gynaecological department of a single centre in China. POPULATION: Patients with uterine fibroids and adenomyosis. METHOD: From January 2011 to August 2015,83 MRI-confirmed uterine fibroid patients and 102 adenomyosis patients who received HIFU treatment at Chongqing Haifu Hospital and attended the 1-year and 6-month follow up, respectively, were included in our retrospective study...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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