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https://www.readbyqxmd.com/read/29168558/outcomes-in-women-undergoing-robotic-assisted-laparoscopic-hysterectomy-compared-to-conventional-laparoscopic-hysterectomy-at-a-tertiary-hospital-in-western-australia
#1
Vinita A Rajadurai, Jason Tan, Stuart G Salfinger, Paul A Cohen
BACKGROUND: Robotic-assisted laparoscopic hysterectomy (RALH) is associated with improved outcomes compared to open surgery in patients with endometrial cancer but data are conflicting when comparing RALH to conventional total laparoscopic hysterectomy (TLH). In October 2014, a RALH program was established in Perth, Western Australia. AIM: To compare outcomes in patients undergoing RALH with a matched cohort undergoing TLH. MATERIALS AND METHODS: A retrospective matched cohort study compared outcomes in 45 patients who underwent RALH with 45 controls who were patients treated with TLH...
November 23, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29164336/stimulation-of-chemokines-in-human-endometrial-stromal-cells-by-tumor-necrosis-factor-%C3%AE-and-interferon-%C3%AE-is-similar-under-apoptotic-and-non-apoptotic-conditions
#2
Julia Spratte, Henriette Princk, Florian Schütz, Joachim Rom, Marek Zygmunt, Herbert Fluhr
PURPOSE: Tumor necrosis factor (TNF)-α and interferon (IFN)-γ are pro-inflammatory cytokines which have been shown to be involved in the pathophysiology of implantation disorders. Both cytokines in combination are able to sensitize primarily resistant human endometrial stromal cells (ESCs) to Fas-induced apoptosis. Since CCL (CC-chemokine ligand) 5 and CCL2 are important regulators of the endometrial immune cell population, we examined the impact of TNF-α and IFN-γ on these two chemokines under non-apoptotic and apoptotic conditions...
November 21, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29163840/an-improved-nerve-sparing-radical-hysterectomy-technique-for-cervical-cancer-using-the-paravesico-vaginal-space-as-a-new-surgical-landmark
#3
Yuqin Zhang, Tingyan Shi, Sheng Yin, Sining Ma, Di Shi, Jun Guan, Libing Xiang, Yang Liu, Yulan Ren, Deyan Tan, Rongyu Zang
Bladder dysfunction remains a major postoperative challenge for early stage cervical cancer patients. The present prospective phase 2 trial in patients with stage IB1 and IIA1 cervical cancer follows up on our previous, unpublished work describing a new surgical landmark, the paravesico-vaginal space. We describe a novel nerve-sparing radical hysterectomy (NSRH) approach to treat early stage cervical cancer without compromising local control rate or survival. Between September 2015 and August 2016, 49 patients were enrolled to receive NSRH...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29162958/serous-tubal-carcinogenesis-the-recent-concept-of-origin-of-ovarian-primary-peritoneal-and-fallopian-tube-high-grade-serous-carcinoma
#4
Tushar Kar, Asaranti Kar, Ipsita Dhal, Sasmita Panda, Priyadarshini Biswal, Bhagyalaxmi Nayak, Niranjan Rout, Sagarika Samantray
Background: Pelvic (non-uterine) high-grade serous carcinomas (PHGSC) including ovarian, tubal and primary peritoneal serous carcinomas have increased death: incidence ratio due to presentation at advanced stage, rapid progression, poor prognosis and high morbidity. Ambiguity regarding their pathogenesis and lack of a proper screening method is the cause of their late detection and high fatality rate. This study was undertaken to assess the fallopian tube for the presence of precursor lesions in pelvic serous carcinoma...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162957/geriatric-pelvic-organ-prolapse-surgery-going-the-extra-mile
#5
Seethalakshmi Krishnan
Background: To assess the quality of life in geriatric patients after reconstructive and obliterative vaginal surgery for advanced pelvic organ prolapse (POP). Methods: Prospective observational study was conducted between January 2009 and December 2014 at the department of Urogynaecology, Government Kasturbha Gandhi Hospital. A total of 424 women (between the age group of 60 and 94 years) with advanced pelvic organ prolapse underwent vaginal hysterectomy along with vaginal apical suspension procedures which were McCalls culdoplasty (35...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162766/production-and-rearing-of-germ-free-x-scid-pigs
#6
Hiromasa Hara, Hiroaki Shibata, Kazuaki Nakano, Tomoyuki Abe, Hideki Uosaki, Takahiro Ohnuki, Shuji Hishikawa, Satoshi Kunita, Masahito Watanabe, Osamu Nureki, Hiroshi Nagashima, Yutaka Hanazono
Pigs with X-linked severe combined immunodeficiency (X-SCID) caused by a mutation of the interleukin-2 receptor gamma chain gene (IL2RG) are of value for a wide range of studies. However, they do not survive longer than 8 weeks because of their susceptibility to infections. To allow longer survival of X-SCID pigs, the animals must be born and reared under germ-free conditions. Here, we established an efficient system for piglet derivation by hysterectomy and used it to obtain and maintain a germ-free X-SCID pig...
November 21, 2017: Experimental Animals
https://www.readbyqxmd.com/read/29161751/the-jellyfish-sign-a-new-sonographic-cervical-marker-to%C3%A2-predict-maternal-morbidity-in-abnormally-invasive-placenta-previa
#7
Emma Bertucci, Filomena Giulia Sileo, Giovanni Grandi, Valentina Fenu, Carlotta Cani, Luciano Mancini, Ema Mataca, Fabio Facchinetti
Purpose To investigate the value of a new cervical sonographic sign, called the jellyfish sign (JS), for predicting the risk of maternal morbidity in cases of abnormally invasive placenta (AIP) previa totalis. Materials and Methods Retrospective evaluation of transvaginal (TV) and transabdominal (TA) scans performed in all singleton pregnancies with placenta previa totalis. JS, i. e. the absence of the normal linear demarcation between the placenta previa and the cervix, was evaluated by TV scans. The presence/severity of AIP and outcomes of maternal morbidity were related to this sign...
November 21, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29160427/review-of-magnetic-resonance-guided-focused-ultrasound-in-the-treatment-of-uterine-fibroids
#8
Pedro Felipe Magalhães Peregrino, Marcos de Lorenzo Messina, Ricardo Dos Santos Simões, José Maria Soares-Júnior, Edmund Chada Baracat
Uterine leiomyoma is the most frequently occurring solid pelvic tumor in women during the reproductive period. Magnetic resonance-guided high-intensity focused ultrasound is a promising technique for decreasing menorrhagia and dysmenorrhea in symptomatic women. The aim of this study is to review the role of Magnetic resonance-guided high-intensity focused ultrasound in the treatment of uterine fibroids in symptomatic patients. We performed a review of the MEDLINE and Cochrane databases up to April 2016. The analysis and data collection were performed using the following keywords: Leiomyoma, High-Intensity Focused Ultrasound Ablation, Ultrasonography, Magnetic Resonance Imaging, Menorrhagia...
October 2017: Clinics
https://www.readbyqxmd.com/read/29159943/retrospective-multicenter-study-of-leaving-the-placenta-in-situ-for-patients-with-placenta-previa-on-a-cesarean-scar
#9
Kei Miyakoshi, Toshimitsu Otani, Eiji Kondoh, Shintaro Makino, Mamoru Tanaka, Satoru Takeda
OBJECTIVE: To investigate maternal outcomes after leaving the placenta in situ for placenta accreta spectrum (PAS) disorders in patients with placenta previa on a cesarean delivery scar. METHODS: The present retrospective study reviewed medical records from women with placenta previa on a cesarean scar underwent perinatal care at secondary- or tertiary-level perinatal centers in Japan between January 1, 2010, and December 31, 2014. Perinatal management was conducted based on each leading obstetrician's discretion...
November 21, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29158923/diffuse-subcutaneous-emphysema-pneumomediastinum-and-pneumothorax-following-robotic-assisted-laparoscopic-hysterectomy
#10
Laryssa Patti, William Haussner, Grant Wei
Robotic assisted laparoscopic surgery is becoming more widely available, but despite its multiple benefits, it is not without risk. This case is of a 62-year-old female who presented to the emergency department for dyspnea two days after robotic assisted laparoscopic hysterectomy. Physical exam revealed diffuse facial, neck, upper extremity, torso, and lower extremity crepitus, which was diagnosed as diffuse subcutaneous air on computed tomography (CT). Imaging also revealed right apical pneumothorax and pneumomediastinum...
2017: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/29157931/alternatives-to-hysterectomy-the-burden-of-fibroids-and-the-quality-of-life
#11
REVIEW
Chelsea Fortin, Rebecca Flyckt, Tommaso Falcone
Uterine fibroids are the most common benign tumor in reproductive-aged women. While the majority of women are asymptomatic, those with symptoms may suffer from abnormal uterine bleeding, infertility, pelvic pain or pressure, and urinary dysfunction. Fibroids represent a significant healthcare burden for women and society as a whole. Women with fibroids have compromised overall quality of life and impairment in many specific domains including work productivity, sexuality, self-image, relationships, and social emotional and physical well-being...
October 20, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29157035/a-new-approach-to-fertility-preserving-surgery-in-patients-with-placenta-accretaplacenta-accreta
#12
Sergey Barinov, Yuliya Tirskaya, Irina Medyannikova, Irina Shamina, Inna Shavkun
BACKGROUND: The aim of this study was to evaluate the efficacy of a novel combined surgical approach utilising: (1) two autonomous balloon Zhukovsky catheters (vaginal and uterine), (2) bilateral ligation of the descending uterine artery branches, (3) external supraplacental pleated sutures, and (4) either excision of a small area of placenta accreta or full metroplasty, for the management of uterine bleeding associated with placenta accreta of various severity. MATERIALS AND METHODS: The study included medical records of 92 pregnant women with placenta accreta undergoing caesarean section...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29157027/urinary-tract-injuries-during-cesarean-section-in-patients-with-morbid-placental-adherence-retrospective-cohort-study
#13
Ahmed Alanwar, Helmy M Al-Sayed, Ahmed M Ibrahim, Ahmed M Elkotb, Ahmed Abdelshafy, Rasha Abdelhadi, Ahmed M Abbas, Hend S Abdelmenam, Tamer Fares, Wael Nossair, Ameer A Abdallah, Haitham Sabaa, Maii Nawara
BACKGROUND/OBJECTIVE: The purpose of this study is to evaluate cases of lower urinary tract injuries during cesarean section with or without hysterectomy in cases with morbid placental adherence. METHODS: This record based retrospective study was conducted at Ain Shams University Maternity Hospital in Cairo, Egypt during the period between January 2014 and December 2016. It included all patients who had urinary tract injuries during cesarean section with or without hysterectomy in the cases with morbid placental adherence and they were collected from files of pregnant women who were admitted at hospital planned for termination of pregnancy...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29154933/opioid-prescription-and-patient-use-following-gynecologic-procedures-a-survey-of-patients-and-providers
#14
Kendall C Griffith, Nisse V Clark, Andrea L Zuckerman, Tanaz R Ferzandi, Kelly N Wright
STUDY OBJECTIVE: To describe opioid distribution and patient use following gynecologic procedures. DESIGN: This is a survey study of physicians and patients composed of two parts: 1) a physician survey on opioid prescribing practices following gynecologic procedures, and 2) a patient survey on opioid consumption following hysterectomy. DESIGN CLASSIFICATION: III SETTING: An urban academic tertiary care hospital. SUBJECTS: 96 gynecologists in the Boston-area...
November 14, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29154931/reducing-the-rate-of-abdominal-hysterectomies-experience-from-a-uk-university-teaching-hospital
#15
EDITORIAL
Vasileios Minas, Nahid Gul, Thomas Aust, David Rowlands
No abstract text is available yet for this article.
November 14, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29154851/effect-of-surgeon-s-experience-on-complications-from-laparoscopic-hysterectomy
#16
Naveiro-Fuentes Mariña, Rodríguez-Oliver Antonio, Fernández-Parra Jorge, González-Paredes Aida, Aguilar-Romero Teresa, Mozas-Moreno Juan
OBJECTIVE: To analyze the effect of learning in two surgeons on complications and conversion to laparotomy during total and subtotal laparoscopic hysterectomy. MATERIAL AND METHODS: We analyzed retrospectively 236 total and subtotal laparoscopic hysterectomies done by two surgeons from the time they first performed the procedure. The interventions were classified in three groups based on the surgeon's experience: the first 75 hysterectomies ("novice period"), the subsequent 75 hysterectomies ("intermediate"), and the subsequent 86 hysterectomies ("routine period")...
November 14, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/29154448/significance-of-bizarre-cells-in-cervical-screening-liquid-based-cytology-a-prospective-study-of-15-cases
#17
O Ondič, R Ferko, J Kičinová, J Bouda, I Kinkorová-Luňáčková, L Kupcová, M Zůchová, J Chytra, T Waloschek, M Tůmová Bartošková, R Alaghehbandan, J Němcová
OBJECTIVE: The aim of this study was to assess the significance of bizarre cells (cells of squamous origin with a superficial squamous cell-type cytoplasm and characterised by multinucleation that produces bizarre nuclear shapes) in liquid-based cytology (LBC) Papanicoaou (pap) smears with clinical and histological follow-up correlation. METHODS: Fifteen patients, all with LBC samples containing bizarre cells, were identified in routine ThinPrep(®) LBC workload...
November 20, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29153540/prognostic-value-of-pre-treatment-human-papilloma-virus-dna-status-in-cervical-cancer
#18
Gun Oh Chong, Yoon Hee Lee, Hyung Soo Han, Hyun Jung Lee, Ji Young Park, Dae Gy Hong, Yoon Soon Lee, Young Lae Cho
OBJECTIVE: Although the relationship between human papilloma virus (HPV) and cervical cancer is well established, the prognostic value of HPV status has not been determined, largely because previous studies have yielded conflicting results. This study aimed to investigate the prognostic value of pre-treatment HPV DNA for predicting tumor recurrence in cervical cancer. METHODS: The study included 248 eligible patients who provided cervical cell specimens for HPV genotyping before surgery or concurrent chemoradiotherapy (CCRT)...
November 15, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29153060/using-pyruvate-kinase-as-a-predictor-for-patient-with-endometrial-cancer-having-complex-hyperplasia-with-atypia-to-prevent-hysterectomy-and-preserve-fertility-retrospective-immunohistochemical-study
#19
Susan Hosseini Nasab, Neda Jooya, Aryan Esmaeili, Neda Zarrin Khameh, Concepcion Diaz-Arrastia, Mazdak Momeni
OBJECTIVES: To explore whether the metabolic switches proceed or succeed the histological changes in precancerous lesions. To validate pyruvate kinase isoform 1 (PKM1) and pyruvate kinase isoform 2 (PKM2) as a histological biomarker to predict the progression of endometrial hyperplasia into invasive cancer status. METHODS: The records of 56 patients with a primary diagnosis of complex hyperplasia with atypia after endometrial biopsy were selected and analyzed retrospectively...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/29152519/primary-carcinosarcoma-of-the-pancreas-with-cd10-positive-sarcoma-component
#20
Christine J Salibay, Julia Rewerska, Shweta Gupta, Nicholas Ree
Carcinosarcomas of the pancreas are rare entities with a dismal prognosis. We report a rare case of pancreatic carcinosarcoma in a 49-year-old African American female who underwent a total abdominal hysterectomy with right salpingo-oophorectomy and exploration of the pancreatic mass. The surgery revealed a sclerotic mass in the body and tail of the pancreas that was surgically unresectable, and a pancreatic biopsy confirmed the pathology of pancreatic carcinosarcoma. Histologically, the lesion showed a high-grade spindle cell sarcoma and adjacent moderately differentiated adenocarcinoma...
October 2017: Journal of Investigative Medicine High Impact Case Reports
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