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https://www.readbyqxmd.com/read/28549078/herod-a-human-ethnic-and-regional-specific-omics-database
#1
Xian Zeng, Lin Tao, Zhang Peng, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng Yong Yang, Zhe Chen, Yu Yang Jiang, Yu Zong Chen
Motivation: Genetic and gene expression variations within and between populations and across geographical regions have substantial effects on the biological phenotypes, diseases, and therapeutic response. The development of precision medicines can be facilitated by the OMICS studies of the patients of specific ethnicity and geographic region. However, there is an inadequate facility for broadly and conveniently accessing the ethnic and regional specific OMICS data. Results: Here, we introduced a new free database, HEROD, a human ethnic and regional specific OMICS database...
May 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28548206/the-phylogeny-and-biogeography-of-hakea-proteaceae-reveals-the-role-of-biome-shifts-in-a-continental-plant-radiation
#2
Marcel Cardillo, Peter H Weston, Zoe K M Reynolds, Peter M Olde, Austin R Mast, Emily Lemmon, Alan R Lemmon, Lindell Bromham
The frequency of evolutionary biome shifts during diversification has important implications for our ability to explain geographic patterns of plant diversity. Recent studies present several examples of biome shifts, but whether frequencies of biome shifts closely reflect geographic proximity or environmental similarity of biomes remains poorly known. We explore this question by using phylogenomic methods to estimate the phylogeny of Hakea, a diverse Australian genus occupying a wide range of biomes. Model-based estimation of ancestral regions indicates that Hakea began diversifying in the Mediterranean biome of southern Australia in the Middle Eocene - Early Oligocene, and dispersed repeatedly into other biomes across the continent...
May 26, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28548188/-epidemiology-of-premature-deaths-in-chile-between-2001-and-2010
#3
Roberto Bächler, Gloria Icaza, Alex Soto, Loreto Núñez, Carolina Orellana, Rolando Monsalve, Marcela Riquelme
BACKGROUND: Years of potential life lost (YPLL) is a parameter that allows to analyze premature deaths. AIM: To study the causes, differences by gender, geographic variations and the trend of premature deaths in the last decade in Chile. MATERIAL AND METHODS: Using death databases published by the Ministry of Health, YPLL were calculated for the decade 2001-2010, using the method proposed by the Organization for Economic Cooperation and Development...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28548005/geographic-variation-in-diagnostic-ability-and-quality-of-care-metrics-a-case-study-of-ankylosing-spondylitis-and-low-back-pain
#4
Jason Shafrin, Jenny Griffith, Jin Joo Shim, Caroline Huber, Arijit Ganguli, Wade Aubry
Studies examining geographic variation in care for low back pain often focus on process and outcome measures conditional on patient diagnosis but generally do not take into account a physician's ability to diagnose the root cause of low back pain. In our case study, we used increased detection of ankylosing spondylitis-a relatively rare inflammatory back disease-as a proxy for diagnostic ability and measured the relationship between ankylosing spondylitis detection, potentially inappropriate low back pain care, and cost...
January 1, 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28547786/the-geography-of-spatial-synchrony
#5
Jonathan A Walter, Lawrence W Sheppard, Thomas L Anderson, Jude H Kastens, Ottar N Bjørnstad, Andrew M Liebhold, Daniel C Reuman
Spatial synchrony, defined as correlated temporal fluctuations among populations, is a fundamental feature of population dynamics, but many aspects of synchrony remain poorly understood. Few studies have examined detailed geographical patterns of synchrony; instead most focus on how synchrony declines with increasing linear distance between locations, making the simplifying assumption that distance decay is isotropic. By synthesising and extending prior work, we show how geography of synchrony, a term which we use to refer to detailed spatial variation in patterns of synchrony, can be leveraged to understand ecological processes including identification of drivers of synchrony, a long-standing challenge...
May 26, 2017: Ecology Letters
https://www.readbyqxmd.com/read/28547520/small-scale-intraspecific-patterns-of-adaptive-immunogenetic-polymorphisms-and-neutral-variation-in-lake-superior-lake-trout
#6
Shauna M Baillie, Riley R Hemstock, Andrew M Muir, Charles C Krueger, Paul Bentzen
Many fishes express high levels of intraspecific variability, often linked to resource partitioning. Several studies show that a species' evolutionary trajectory of adaptive divergence can undergo reversals caused by changes in its environment. Such a reversal in neutral genetic and morphological variation among lake trout Salvelinus namaycush ecomorphs appears to be underway in Lake Superior. However, a water depth gradient in neutral genetic divergence was found to be associated with intraspecific diversity in the lake...
May 25, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28547345/where-are-adults-active-an-examination-of-physical-activity-locations-using-gps-in-five-us-cities
#7
Katelyn M Holliday, Annie Green Howard, Michael Emch, Daniel A Rodríguez, Wayne D Rosamond, Kelly R Evenson
Increasing physical activity (PA) at the population level requires appropriately targeting intervention development. Identifying the locations in which participants with various sociodemographic, body weight, and geographic characteristics tend to engage in varying intensities of PA as well as locations these populations underutilize for PA may facilitate this process. A visual location-coding protocol was developed and implemented in Google Fusion Tables and Maps using data from participants (N = 223, age 18-85) in five states...
May 25, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28546940/refractive-errors-among-children-adolescents-and-adults-attending-eye-clinics-in-mexico
#8
Francisco Gomez-Salazar, Abraham Campos-Romero, Humberto Gomez-Campaña, Cinthia Cruz-Zamudio, Mariano Chaidez-Felix, Nidia Leon-Sicairos, Jorge Velazquez-Roman, Hector Flores-Villaseñor, Secundino Muro-Amador, Alma Marlene Guadron-Llanos, Javier J Martinez-Garcia, Joel Murillo-Llanes, Jaime Sanchez-Cuen, Alejando Llausas-Vargas, Gerardo Alapizco-Castro, Ana Irineo-Cabrales, Enrique Graue-Hernandez, Tito Ramirez-Luquin, Adrian Canizalez-Roman
AIM: To assess the proportion of refractive errors in the Mexican population that visited primary care optometry clinics in fourteen states of Mexico. METHODS: Refractive data from 676 856 patients aged 6 to 90y were collected from optometry clinics in fourteen states of Mexico between 2014 and 2015. The refractive errors were classified by the spherical equivalent (SE), as follows: sphere+½ cylinder. Myopia (SE>-0.50 D), hyperopia (SE>+0.50 D), emmetropia (-0...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28546786/the-association-between-higher-nurse-staffing-standards-in-the-fee-schedules-and-the-geographic-distribution-of-hospital-nurses-a-cross-sectional-study-using-nationwide-administrative-data
#9
Noriko Morioka, Jun Tomio, Toshikazu Seto, Yasuki Kobayashi
BACKGROUND: In Japan, the revision of the fee schedules in 2006 introduced a new category of general care ward for more advanced care, with a higher staffing standard, a patient-to-nurse ratio of 7:1. Previous studies have suggested that these changes worsened inequalities in the geographic distribution of nurses, but there have been few quantitative studies evaluating this effect. This study aimed to investigate the association between the distribution of 7:1 beds and the geographic distribution of hospital nursing staffs...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28546554/high-throughput-resistance-profiling-of-plasmodium-falciparum-infections-based-on-custom-dual-indexing-and-illumina-next-generation-sequencing-technology
#10
Sidsel Nag, Marlene D Dalgaard, Poul-Erik Kofoed, Johan Ursing, Marina Crespo, Lee O'Brien Andersen, Frank Møller Aarestrup, Ole Lund, Michael Alifrangis
Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility to antimalarial drugs as well as its geographical origin. Both of these factors are key to monitoring development and spread of antimalarial drug resistance. In this study, we combine multiplex PCR, custom designed dual indexing and Miseq sequencing for high throughput SNP-profiling of 457 malaria infections from Guinea-Bissau, at the cost of 10 USD per sample. By amplifying and sequencing 15 genetic fragments, we cover 20 resistance-conferring SNPs occurring in pfcrt, pfmdr1, pfdhfr, pfdhps, as well as the entire length of pfK13, and the mitochondrial barcode for parasite origin...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546305/national-survey-of-pharmacy-residents-nearing-completion-of-the-2014-15-residency-year
#11
Bryan M Bishop, Janet A Silvester, Christina Y Martin, Colleen G Bush
PURPOSE: The results of a national survey targeting postgraduate year 1 (PGY1) and postgraduate year 2 (PGY2) resident's perceptions of their residency programs and postresidency job prospects are presented. METHODS: An electronic survey was distributed to PGY1 and PGY2 residents identified through the ASHP membership database. The survey asked basic demographic questions, questions related to the residency experience (satisfaction, hours spent on various general activities such as patient care, research, and staffing), and various questions related to residents' job search and future career plans (search methods, outcomes, and satisfaction with the process)...
June 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28546079/pioneer-study-of-population-genetics-of-rhodnius-ecuadoriensis-hemiptera-reduviidae-from-the-central-coast-and-southern-andean-regions-of-ecuador
#12
Anita G Villacís, Paula L Marcet, César A Yumiseva, Ellen M Dotson, Michel Tibayrenc, Simone Frédérique Brenière, Mario J Grijalva
Effective control of Chagas disease vector populations requires a good understanding of the epidemiological components, including a reliable analysis of the genetic structure of vector populations. Rhodnius ecuadoriensis is the most widespread vector of Chagas disease in Ecuador, occupying domestic, peridomestic and sylvatic habitats. It is widely distributed in the central coast and southern highlands regions of Ecuador, two very different regions in terms of bio-geographical characteristics. To evaluate the genetic relationship among R...
May 22, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28546050/shared-decision-making-in-argentina-in-2017
#13
Mariela Barani, Karin Kopitowski, Carolina Carrara, María Victoria Ruiz Yanzi
Argentina is a high-middle income country located in Southern South America with an estimated population of 44 million inhabitants. The epidemiological profile of the population is characterised by an increase of non-communicable diseases. The health system is heterogeneous, fragmented and loosely integrated. There are no unified research agenda or government initiatives encouraging the implementation of and research on Shared Decision-Making (SDM). Progress has been made lately to respect patient autonomy through the enactment of the 'Patients' Rights Act', which expressly enshrines the right of patients to get information as a key element of decision-making...
May 22, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28546049/gunshot-induced-injuries-in-orthopaedic-trauma-research-a-bibliometric-analysis-of-the-most-influential-literature
#14
REVIEW
Michael Held, Esmee Engelmann, Robert Dunn, Sufian S Ahmad, Maritz Laubscher, Marius J B Keel, Sithombo Maqungo, Sven Hoppe
INTRODUCTION: A growing burden of gunshot injuries demands evidence-based ballistic trauma management. No comprehensive systematic overview of the current knowledge is available to date. This study aims to identify and analyze the most influential publications in the field of orthopedic ballistic trauma research. MATERIAL AND METHODS: All databases available in the Thomson Reuters Web of Knowledge were searched to conduct this bibliometrical study. The most cited orthopedic ballistic trauma articles published between 1950 and 2015 were identified by use of a multi-step approach...
May 22, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28545826/gamified-twitter-microblogging-to-support-resident-preparation-for-the-american-board-of-surgery-in-service-training-examination
#15
Laura C Lamb, Monica M DiFiori, Vijay Jayaraman, Brian D Shames, James M Feeney
OBJECTIVE: We sought to determine if a daily gamified microblogging project improves American Board of Surgery In-Service Training Examination (ABSITE) scores for participants. DESIGN: In July 2016, we instituted a gamified microblogging project using Twitter as the platform and modified questions from one of several available question banks. A question of the day was posted at 7-o׳clock each morning, Monday through Friday. Respondents were awarded points for speed, accuracy, and contribution to discussion topics...
May 22, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28545582/gender-differences-in-hypertension-awareness-antihypertensive-use-and-blood-pressure-control-in-bangladeshi-adults-findings-from-a-national-cross-sectional-survey
#16
Muntasirur Rahman, Gail Williams, Abdullah Al Mamun
BACKGROUND: Bangladesh is facing an epidemiological transition with a growing burden of non-communicable diseases. Traditionally, hypertension and associated complications in women receive less recognition, and there is a dearth of related publications. The study aims to explore gender differences in high blood pressure awareness and antihypertensive use in Bangladeshi adults at the community level. Another objective is to identify factors associated with uncontrolled hypertension among antihypertensive users...
May 25, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28545432/the-impact-of-migratory-flyways-on-the-spread-of-avian-influenza-virus-in-north-america
#17
Mathieu Fourment, Aaron E Darling, Edward C Holmes
BACKGROUND: Wild birds are the major reservoir hosts for influenza A viruses (AIVs) and have been implicated in the emergence of pandemic events in livestock and human populations. Understanding how AIVs spread within and across continents is therefore critical to the development of successful strategies to manage and reduce the impact of influenza outbreaks. In North America many bird species undergo seasonal migratory movements along a North-South axis, thereby providing opportunities for viruses to spread over long distances...
May 25, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28545417/community-level-characteristics-and-environmental-factors-of-child-respiratory-illnesses-in-southern-arizona
#18
Nathan Lothrop, Khaleel Hussaini, Dean Billheimer, Paloma Beamer
BACKGROUND: Lower respiratory illnesses (LRIs) and asthma are common diseases in children <5 years of age. Few studies have investigated the relationships between multiple, home-based social and environmental risk factors and asthma and LRIs in children. Of those that have, none have focused exclusively on children <5 years of age, who are more physiologically vulnerable and spend more time at home compared to older children. Further, no studies have done so at the community level...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28545396/transcriptomic-resources-for-the-medicinal-legume-mucuna-pruriens-de-novo-transcriptome-assembly-annotation-identification-and-validation-of-est-ssr-markers
#19
N Sathyanarayana, Ranjith Kumar Pittala, Pankaj Kumar Tripathi, Ratan Chopra, Heikham Russiachand Singh, Vikas Belamkar, Pardeep Kumar Bhardwaj, Jeff J Doyle, Ashley N Egan
BACKGROUND: The medicinal legume Mucuna pruriens (L.) DC. has attracted attention worldwide as a source of the anti-Parkinson's drug L-Dopa. It is also a popular green manure cover crop that offers many agronomic benefits including high protein content, nitrogen fixation and soil nutrients. The plant currently lacks genomic resources and there is limited knowledge on gene expression, metabolic pathways, and genetics of secondary metabolite production. Here, we present transcriptomic resources for M...
May 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28545386/evolutionary-radiations-in-the-species-rich-mountain-genus-saxifraga-l
#20
J Ebersbach, J Schnitzler, A Favre, A N Muellner-Riehl
BACKGROUND: A large number of taxa have undergone evolutionary radiations in mountainous areas, rendering alpine systems particularly suitable to study the extrinsic and intrinsic factors that have shaped diversification patterns in plants. The species-rich genus Saxifraga L. is widely distributed throughout the Northern Hemisphere, with high species numbers in the regions adjacent to the Qinghai-Tibet Plateau (QTP) in particular the Hengduan Mountains and the Himalayas. Using a dataset of 297 taxa (representing at least 60% of extant Saxifraga species), we explored the variation of infrageneric diversification rates...
May 25, 2017: BMC Evolutionary Biology
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