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https://www.readbyqxmd.com/read/28939165/decrease-in-nmda-receptor-signalling-activity-in-the-anterior-cingulate-cortex-diminishes-defensive-behaviour-and-unconditioned-fear-induced-antinociception-elicited-by-gabaergic-tonic-inhibition-impairment-in-the-posterior-hypothalamus
#1
Luiz Luciano Falconi-Sobrinho, Tayllon Dos Anjos-Garcia, Ricardo de Oliveira, Norberto Cysne Coimbra
Acute γ-aminobutyric acid (GABA) disinhibition in the posterior hypothalamus (PH) elicits defensive reactions that are considered anxiety- and panic attack-like behaviour, and these defensive reactions are followed by antinociception. Evidence indicates that the PH connects with the medial prefrontal cortex, particularly the anterior cingulate cortex (ACC), which seems to regulate these unconditioned fear-induced defensive responses. However, few studies have shown the participation of cortical regions in the control of behavioural and antinociceptive responses organised by diencephalic structures...
September 19, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28937941/the-scheduling-of-kratom-and-selective-use-of-data
#2
O Hayden Griffin, Megan E Webb
Kratom is a traditional drug from Southeast Asia that has been an emerging new substance in the United States. On August 30, 2016, the DEA announced the intention to emergency schedule kratom into Schedule I. To support this decision, the DEA cited an increase in drug seizures of kratom and an increase in calls to poison control concerning kratom. However, a short time later, on October 12, 2016, the DEA withdrew the intent to schedule kratom after public and congressional backlash. The withdrawal by the DEA was somewhat unprecedented...
September 22, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28935440/effects-of-acute-restraint-and-unpredictable-chronic-mild-stress-on-brain-corticotrophin-releasing-factor-mrna-in-the-elevated-t-maze
#3
José S de Andrade, Isabel C Céspedes, Renata O Abrão, Joelcimar M da Silva, Ricardo Ceneviva, Daniel Araki Ribeiro, Jackson C Bittencourt, Milena B Viana
Corticotrophin releasing factor (CRF) modulates stress/anxiety-related responses. Previous studies showed that exposure to acute restraint and unpredictable chronic mild stress (UCMS) facilitates elevated T-maze (ETM) avoidance responses, an anxiogenic-like effect. This study verified the role of CRF in the modulation of ETM avoidance and escape reactions, in unstressed rats and in animals exposed to acute restraint or to UCMS, by quantifying CRF mRNA concentrations in stress/anxiety-related brain regions, through semiquantitative in situ hybridization...
September 18, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28927484/validation-of-telephone-based-behavioral-assessments-in-aging-services-clients
#4
Yeates Conwell, Adam Simning, Nicole Driffill, Yinglin Xia, Xin Tu, Susan P Messing, David Oslin
BACKGROUND: The Behavioral Health Laboratory (BHL), a telephone-based mental health assessment, is a cost-effective approach that can improve mental illness identification and management. The individual BHL instruments, which were originally designed to be administered in-person, have not yet been validated with an in-person BHL assessment. This study therefore aims to characterize the concordance between the BHL data gathered by telephone and in-person interviews. METHODS: A cross-sectional study was conducted with English-speaking aging services network (ASN) clients aged 60 years and older in Monroe County, NY who were randomized to a BHL interview either in-person (n = 55) or by telephone (n = 53)...
September 20, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28926674/prior-mental-disorders-and-lifetime-suicidal-behaviors-among-us-army-soldiers-in-the-army-study-to-assess-risk-and-resilience-in-servicemembers-army-starrs
#5
Alexander J Millner, Robert J Ursano, Irving Hwang, Andrew J King, James A Naifeh, Nancy A Sampson, Alan M Zaslavsky, Murray B Stein, Ronald C Kessler, Matthew K Nock
We report on associations of retrospectively reported temporally prior mental disorders and Army career characteristics with subsequent first onset of suicidal behaviors in a large, representative sample of US Army soldiers who participated in the Consolidated All-Army Survey of the Army Study to Assess Risk and Resilience in Servicemembers (N = 29,982). Results reveal that among men and women, all self-reported lifetime disorders measured (some assessed with screening scales) are associated with subsequent onset of suicide ideation...
September 19, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28926359/personality-traits-in-panic-disorder-patients-with-and-without-comorbidities
#6
Morena M Zugliani, Rocio Martin-Santos, Antonio Egidio Nardi, Rafael Christophe Freire
Panic disorder (PD) is often correlated with high neuroticism and low extraversion. This study aims to ascertain whether PD patients differ from healthy controls in regard to personality traits and determine if these traits are correlated with comorbid disorders, anxiety, and depression symptoms. Personality traits of 69 PD patients and 42 controls were compared using the Maudsley Personality Inventory. In PD patients, comorbidities, anxiety, and depression symptoms were also evaluated. PD patients showed higher neuroticism and lower extraversion compared with healthy controls...
September 18, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28923431/both-anxiety-and-joint-laxity-determine-the-olfactory-features-in-panic-disorder
#7
Emma Burón, Antonio Bulbena, Andrea Bulbena-Cabré, Sílvia Rosado, Guillem Pailhez
Previous research showed a high sensitivity in sensorial modalities in panic disorder (PD). This disorder has been consistently associated to the joint hypermobility syndrome (JHS). In non-clinical samples, this collagen alteration has been also related to an enhanced sensitivity in some sensorial modalities. The main aim of this study is to explore the olfactory functioning in PD in relation to JHS. Sixty patients with PD and sixty healthy controls performed the Sniffin' Sticks Test (SST) (threshold subtest), and completed the Affective Impact of Odors scale (AIO), the Relational Scale of Olfaction (EROL), and the Odor Awareness Scale (OAS)...
September 11, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28922735/assessing-the-interplay-of-childhood-adversities-with-more-recent-stressful-life-events-and-conditions-in-predicting-panic-pathology-among-adults-from-the-general-population
#8
E Asselmann, J Stender, H J Grabe, J König, C O Schmidt, A O Hamm, C A Pané-Farré
BACKGROUND: Although research suggests that (a) childhood adversities and more recent stressful life events/conditions are risk factors for panic pathology and that (b) early life stress increases vulnerability to later psychopathology, it remains unclear whether childhood adversities amplify the association between more recent stressful life events/conditions and panic pathology. METHODS: Data were derived from a general population sample (Study of Health in Pomerania, SHIP)...
August 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28918162/how-high-level-of-anxiety-in-panic-disorder-can-interfere-in-working-memory-a-computer-simulation-and-electrophysiological-investigation
#9
Luiza Wanick Di Giorgio Silva, Danielle Aprigio, Jesse Di Giacomo, Mariana Gongora, Henning Budde, Juliana Bittencourt, Mauricio Cagy, Silmar Teixeira, Pedro Ribeiro, Marcele Regine de Carvalho, Rafael Freire, Antonio Egidio Nardi, Luis Fernando Basile, Bruna Velasques
Panic disorder (PD) is characterized by repeated and unexpected attacks of intense anxiety, which are not restricted to a determined situation or circumstance. The coherence function has been used to investigate the communication among brain structures through the quantitative EEG (qEEG). The objective of this study is to analyze if there is a difference in frontoparietal gamma coherence (GC) between panic disorder patients (PDP) and healthy controls (HC) during the Visual oddball paradigm; and verify if high levels of anxiety (produced by a computer simulation) affect PDP's working memory...
September 11, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28913713/ethnic-groups-differ-in-how-poor-self-rated-mental-health-reflects-psychiatric-disorders
#10
Shervin Assari
AIM: This study aimed to explore cross-ethnic variation in the pattern of the associations between psychiatric disorders and self-rated mental health (SRMH) in the USA. METHODS: This cross-sectional study used data from the Collaborative Psychiatric Epidemiology Surveys (CPES), 2001-2003, a national household probability sample. The study enrolled 18,237 individuals who were either Non-Hispanic White (n = 7587), African American (n = 4746), Mexican (n = 1442), Cuban (n = 577), Puerto Rican (n = 495), Other Hispanic (n = 1106), Vietnamese (n = 520), Filipino (n = 508), Chinese (n = 600) or Other Asian (n = 656)...
September 14, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28903165/association-of-panic-disorder-generalized-anxiety-disorder-and-benzodiazepine-treatment-during-pregnancy-with-risk-of-adverse-birth-outcomes
#11
Kimberly Ann Yonkers, Kathryn Gilstad-Hayden, Ariadna Forray, Heather S Lipkind
Importance: Registry data show that maternal panic disorder, or anxiety disorders in general, increase the risk for adverse pregnancy outcomes. However, diagnoses from registries may be imprecise and may not consider potential confounding factors, such as treatment with medication and maternal substance use. Objective: To determine whether panic disorder or generalized anxiety disorder (GAD) in pregnancy, or medications used to treat these conditions, are associated with adverse maternal or neonatal pregnancy outcomes...
September 13, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28900368/testing-lupus-anticoagulants-in-a-real-life-scenario-a-retrospective-cohort-study
#12
Franz Ratzinger, Tanja Panic, Helmuth Haslacher, Thomas Perkmann, Klaus G Schmetterer, Sabine Belik, Georg Maenner, Ingrid Pabinger, Peter Quehenberger
INTRODUCTION: Lupus anticoagulant (LAC) testing is challenging. Most data are derived from a well-controlled study environment with potential alterations to daily routines. The aim of this retrospective cohort study was to assess the capacity of various LAC screening tests and derived mixing tests to predict a positive result in subsequent confirmation tests in a large cohort of patients. MATERIALS AND METHODS: In 5832 individuals, we retrospectively evaluated the accuracy of the aPTT-A, aPTT-LAscreen, aPTT-FS and dRVVTscreen and of their derived mixing tests in detecting a positive confirmation test result within the same blood specimen...
October 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28895128/transitional-justice-as-social-control-political-transitions-human-rights-norms-and-the-reclassification-of-the-past
#13
Ron Dudai
This article offers an interpretation of transitional justice policies - the efforts of post-conflict and post-dictatorship societies to address the legacy of past abuses - as a form of social control. While transitional justice is commonly conceptualized as responding to a core problem of impunity, this article argues that such formulation is too narrow and leads to lack of coherence in the analysis of the diverse array of transitional mechanisms, which include among others trials, truth commissions, reparations for victims and apologies...
September 12, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28893114/panic-disorder-and-cardiovascular-diseases-an-overview
#14
Sergio Machado, Federica Sancassiani, Flavia Paes, Nuno Rocha, Eric Murillo-Rodriguez, Antonio Egidio Nardi
The association between panic disorder (PD) and cardiovascular diseases (CVD) has been extensively studied in recent years and, although some studies have shown anxiety disorders co-existing or increasing the risk of heart disease, no causal hypothesis has been well established. Thus, a critical review was performed of the studies that evaluated the association between PD and cardiovascular diseases; synthesizing the evidence on the mechanisms mediators that theoretically would be the responsible for the causal pathway between PD and CVD, specifically...
September 12, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28891770/treating-panic-disorder-hypnotically
#15
David B Reid
A hypnosis protocol for treating panic disorder is provided. The implementation of this protocol is demonstrated through a case example involving the successful treatment of a 28-year-old firefighter presenting with a 4-month history of near-daily panic attacks. Core principles associated with this protocol include: (1) Elementary education about the physiology of panic; (2) A review of primary factors contributing to the evolution and manifestation of panic; (3) Encouragement of physical activity; (4) Utilization of hypnosis applications; and (5) Monitoring and measuring progress evidenced by a reduction in the frequency and intensity of panic attacks...
October 2017: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/28890837/why-it-is-not-always-anxiety-a-tough-diagnosis-of-stiff-person-syndrome
#16
Carmen Elena Cervantes, Hsien Lee Lau, Tina Ataian Binazir, Keith O O'Brien, Jonathan S Cross
Anxiety disorder is a commonly used diagnosis that may mask underlying conditions. Stiff person syndrome (SPS) is a rare neuroimmunological disorder characterized by progressive rigidity and painful muscle spasms affecting axial and lower extremity musculature. These episodes can be triggered by sudden movement, noise, or emotional stress, which may present as a psychiatric condition. We report the case of a 30-year-old female who presented with recurrent panic attacks with multiple prior hospital admissions for anxiety, rigidity, and difficulty in walking...
2017: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/28889251/a-10-year-prospective-longitudinal-study-of-daily-hassles-and-incident-psychopathology-among-adolescents-and-young-adults-interactions-with-gender-perceived-coping-efficacy-and-negative-life-events
#17
Eva Asselmann, Hans-Ulrich Wittchen, Roselind Lieb, Katja Beesdo-Baum
PURPOSE: To prospectively examine whether higher daily hassles predict a variety of incident mental disorders and respective associations vary by gender, age, perceived coping efficacy and number of negative life events. METHODS: Data comes from the Early Developmental Stages of Psychopathology Study (EDSP), a prospective-longitudinal study among adolescents and young adults from the community (n = 2797, aged 14-24 at baseline) followed up in up to 3 assessment waves over 10 years...
September 9, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28883770/frequency-of-depression-and-its-correlation-with-quality-of-life-of-patients-with-oral-cavity-cancer
#18
Senada Dzebo, Jasmina Mahmutovic, Hasiba Erkocevic, Faris Foco
INTRODUCTION: the effects of malignant tumors of oral cavity may be reflected through mental, physical, social and emotional well-being and quality of life of patients. Those suffering from malignancies show a large degree of psychological problems (fear, anxiety, depression, panic disorders, phobias) both at the time of diagnosis and during the treatment. AIM: to determine a level of depression in patients with oral cavity cancer and to link quality of life and level of depression of patients with oral cavity cancer...
June 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28878812/an-arabic-translation-reliability-and-validation-of-patient-health-questionnaire-in-a-saudi-sample
#19
Ahmad N AlHadi, Deemah A AlAteeq, Eman Al-Sharif, Hamdah M Bawazeer, Hasan Alanazi, Abdulaziz T AlShomrani, Raafat M Shuqdar, Reem AlOwaybil
BACKGROUND: Psychological disorders including depression and anxiety are not rare in primary care clinics. The Patient Health Questionnaire (PHQ) is a clinical diagnostic tool that is widely utilized by primary health care physicians worldwide because it provides a practical in-clinic tool to screen for psychological disorders. This study evaluated the validity of the Arabic version of the PHQ in all six modules including depression, anxiety, somatic, panic, eating, and alcohol abuse disorders...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28878702/stigma-stop-a-serious-game-against-the-stigma-toward-mental-health-in-educational-settings
#20
Adolfo J Cangas, Noelia Navarro, José M A Parra, Juan J Ojeda, Diego Cangas, Jose A Piedra, Jose Gallego
This paper presents the results from the application of a serious game called Stigma-Stop among a group of high school students with the aim of reducing the stigma toward mental illnesses. The video game features characters with various mental disorders (schizophrenia, depression, bipolar disorder, and panic disorder with agoraphobia) and provides information about these problems. Additionally, the game asks players about whether they have ever felt the same as the characters, if they believe the characters are psychologically well, and if they think they could help these individuals...
2017: Frontiers in Psychology
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