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https://www.readbyqxmd.com/read/28714775/the-implementation-of-guided-internet-based-cognitive-behaviour-therapy-for-panic-disorder-in-a-routine-care-setting-effectiveness-and-implementation-efforts
#1
Tine Nordgreen, Rolf Gjestad, Gerhard Andersson, Per Carlbring, Odd E Havik
Panic disorder is a common mental disorder. Guided Internet-based cognitive behavioural therapy (Guided Internet-based cognitive behaviour therapy (ICBT)) is a promising approach to reach more people in need of help. In the present effectiveness study, we investigated the outcome of guided ICBT for panic disorder after implementation in routine care. A total of 124 patients were included in the study, of which 114 started the treatment. Large within-group effect sizes were observed on the primary panic disorder symptoms (post-treatment: d = 1...
July 17, 2017: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/28712090/does-prior-traumatization-affect-the-treatment-outcome-of-cbt-for-panic-disorder-the-potential-role-of-the-maoa-gene-and-depression-symptoms
#2
Sebastian Trautmann, Jan Richter, Markus Muehlhan, Michael Höfler, Hans-Ulrich Wittchen, Katharina Domschke, Andreas Ströhle, Alfons O Hamm, Heike Weber, Tilo Kircher, Volker Arolt, Alexander L Gerlach, Georg W Alpers, Thomas Fydrich, Thomas Lang, Andreas Reif
Although cognitive behavioral therapy (CBT) is highly effective in the treatment of anxiety disorders, many patients still do not benefit. This study investigates whether a history of traumatic event experience is negatively associated with outcomes of CBT for panic disorder. The moderating role of the monoamine oxidase A (MAOA) gene and depression symptoms as well as the association between trauma history and fear reactivity as a potential mechanism are further analyzed. We conducted a post-hoc analysis of 172 male and 60 female patients with panic disorder treated with CBT in a multi-center study...
July 15, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28706039/when-an-emerging-disease-becomes-endemic
#3
REVIEW
Graham F Medley, Anna Vassall
Epidemics, such as HIV in the early 1980s and Ebola in 2014, inspire decisive government investment and action, and individual and societal concern, sometimes bordering on panic. By contrast, endemic diseases, such as HIV in 2017 and tuberculosis, struggle to maintain the same attention. For many, the paradox is that endemic disease, in its totality, continues to impose a far higher public health burden than epidemic disease. Overall, the swift political response to epidemics has resulted in success. It has proven possible to eradicate epidemic diseases, often without the availability of vaccines and other biomedical technologies...
July 14, 2017: Science
https://www.readbyqxmd.com/read/28690014/psychiatric-symptoms-in-myoclonus-dystonia-syndrome-are-just-concomitant-features-regardless-of-the-sgce-gene-mutation
#4
Ji-Young Kim, Woong-Woo Lee, Chae Won Shin, Han-Joon Kim, Sung-Sup Park, Sun Ju Chung, Jin Whan Cho, Ho-Sung Ryu, Tae Ok Son, Beomseok Jeon
INTRODUCTION: Among myoclonus-dystonia syndrome (MD) patients, psychiatric disorders including depression, anxiety, alcohol dependence, obsessive-compulsive disorder (OCD) and panic disorder have been frequently reported to be related with the epsilon-sarcoglycan gene (SGCE) mutation. However, the rate of psychiatric disorders has not been compared between MD patients with the SGCE mutation (SGCE (+)) and without the SGCE mutation (SGCE (-)). We analyzed the psychiatric data in both SGCE (+) and SGCE (-) MD patients to determine the association of the SGCE mutation with psychiatric disorders in MD...
June 23, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28689754/sociodemographic-and-clinical-correlates-of-psychotic-symptoms-in-the-general-population-findings-from-the-mhgp-survey
#5
Baptiste Pignon, Franck Schürhoff, Andrei Szöke, Pierre A Geoffroy, Renaud Jardri, Jean-Luc Roelandt, Benjamin Rolland, Pierre Thomas, Guillaume Vaiva, Ali Amad
BACKGROUND: We aimed to explore the sociodemographic and psychiatric correlates of psychotic symptoms in a large general population sample. METHODS: The French Mental Health in the General Population cross-sectional survey interviewed 38,694 individuals using the Mini International Neuropsychiatric Interview. We looked for associations between the presence of lifetime psychotic symptoms, sociodemographic characteristics (including migrant status over three generations) and clinical characteristics...
July 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28686068/differential-associations-between-excess-body-weight-and-psychiatric-disorders-in-men-and-women
#6
Mathilde M Husky, Carolyn M Mazure, Alexis Ruffault, Cécile Flahault, Viviane Kovess-Masfety
BACKGROUND: The current investigation is the first large-scale population-based study from France that documents the association between excess body weight and common psychiatric disorders, and examines the influence of gender on the association between excess body weight and these disorders. A recent plan has been implemented in France to treat the rising rate of those who are overweight or obese, and we seek to demonstrate whether integrated treatment of excess weight and psychiatric conditions appears as indicated...
July 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28686009/ferrocenyl-ruthenocenyl-and-benzyl-oxamniquine-derivatives-with-cross-species-activity-against-schistosoma-mansoni-and-schistosoma-haematobium
#7
Jeannine Hess, Gordana Panic, Malay Patra, Luciano Mastrobuoni, Bernhard Spingler, Saonli Roy, Jennifer Keiser, Gilles Gasser
Schistosomiasis is a parasitic disease that affects more than 250 million people annually, mostly children in poor, tropical, rural areas. Only one treatment (praziquantel) is available, putting control efforts at risk should resistance occur. In pursuit of treatment alternatives, we derivatized an old antischistosomal agent, oxamniquine (OXA). Four organometallic derivatives of OXA were synthesized and tested against Schistosoma mansoni in vitro and in vivo. Of these, a ferrocenyl derivative, 1, killed larval and adult worms 24 h postexposure in vitro, in contrast to OXA, which lacks in vitro activity against adult worms...
July 18, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28675995/ebola-epidemics-control-origin-and-therapeutics
#8
Da Yong Lu, Hong Ying Wu, Nagendra Sastry Yarla, Ting-Ren Lu, Bin Xu, Jian -Ding
Ebola epidemic in Africa was outbreak again in 2014 that arises a new wave of panic worldwide. There is a high mortality rates (30-70%) among Ebola infected people in virus-stricken areas. The direct communications between affected countries and rest of world were cut off then. But the medical capabilities against this deadly viral disease were provided by a limited number of agents, several patented agents, biotherapies or prophylactic/therapeutic vaccines have been entering into clinical validations and will be further developed into the global markets-including patents of small molecular chemicals, short sequences or oligomers of DNA/RNA, linkages of chemicals with bio-molecules, herbal medicine and so on...
July 3, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28674951/the-impact-of-refugee-mothers-trauma-posttraumatic-stress-and-depression-on-their-children-s-adjustment
#9
Patricia L East, Sheila Gahagan, Wael K Al-Delaimy
The mechanisms linking refugee parents' trauma onto their children's functioning are not well understood. The current study sought to identify how Somali refugee mothers' past trauma and current mental health impact their children's psychosocial adjustment. One hundred and ninety-eight Somali mothers (M age = 39 years) and their children (M age = 10 years; 56% male) were studied. On average, mothers spent 7 years in refugee camps, experienced significant trauma, and some had been tortured. Measures of mothers' posttraumatic stress and depression were analyzed as three symptom clusters: volatility/panic, withdrawn/detached, and depressed mood...
July 3, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28673930/short-term-efficacy-of-psychological-and-psychopharmacological-interventions-for-panic-disorder-appears-not-to-be-different
#10
EDITORIAL
Asle Hoffart
No abstract text is available yet for this article.
July 3, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28670907/recovery-of-percent-vital-capacity-by-breathing-training-in-patients-with-panic-disorder-and-impaired-diaphragmatic-breathing
#11
Tatsuji Yamada, Akiomi Inoue, Kosuke Mafune, Hisanori Hiro, Shoji Nagata
Slow diaphragmatic breathing is one of the therapeutic methods used in behavioral therapy for panic disorder. In practice, we have noticed that some of these patients could not perform diaphragmatic breathing and their percent vital capacity was initially reduced but could be recovered through breathing training. We conducted a comparative study with healthy controls to investigate the relationship between diaphragmatic breathing ability and percent vital capacity in patients with panic disorder. Our findings suggest that percent vital capacity in patients with impaired diaphragmatic breathing was significantly reduced compared with those with normal diaphragmatic breathing and that diaphragmatic breathing could be restored by breathing training...
June 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/28670837/analytical-methodologies-for-the-stereoselective-determination-of-fluoxetine-an-overview
#12
REVIEW
Gabriel Hancu, Melania Cârcu-Dobrin, Monica Budău, Aura Rusu
Fluoxetine is a widely used antidepressant belonging to the selective serotonin reuptake inhibitor class; used in the treatment of major depression, obsessive compulsive, premenstrual dysphoric, panic and post-traumatic stress disorders. Fluoxetine is an optical active pharmaceutical substance, which is used as a racemate in therapy, but stereospecific interactions associated with the serotonin-reuptake carrier, for both the parent drug and its active metabolite, norfluoxetine, has been described in the literature...
July 3, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28670127/suicide-and-lyme-and-associated-diseases
#13
Robert C Bransfield
PURPOSE: The aim of this paper is to investigate the association between suicide and Lyme and associated diseases (LAD). No journal article has previously performed a comprehensive assessment of this subject. INTRODUCTION: Multiple case reports and other references demonstrate a causal association between suicidal risk and LAD. Suicide risk is greater in outdoor workers and veterans, both with greater LAD exposure. Multiple studies demonstrate many infections and the associated proinflammatory cytokines, inflammatory-mediated metabolic changes, and quinolinic acid and glutamate changes alter neural circuits which increase suicidality...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28667086/suitable-support-for-anxious-hospice-patients-what-do-nurses-know-do-and-need-an-explanatory-mixed-method-study
#14
Danielle Zweers, Everlien de Graaf, Saskia Teunissen
OBJECTIVE: To provide insight into what nurses know, do and need to provide support to anxious patients in hospice care (HC). METHODS: A mixed method study consisted of an online survey and focus groups (FGs) about what nurses know, do, and need was conducted. 336 HC nurses were invited to participate. Descriptive statistics were computed using SPSS. The χ(2) and t-tests were conducted to compare. The FGs were transcribed verbatim and thematically analysed. RESULTS: The survey was completed by 265 nurses (79%), and five FGs (n=25) were conducted...
June 30, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28666366/child-maltreatment-and-clinical-outcome-in-individuals-at-ultra-high-risk-for-psychosis-in-the-eu-gei-high-risk-study
#15
Tamar C Kraan, Eva Velthorst, Manouk Themmen, Lucia Valmaggia, Matthew J Kempton, Phillip McGuire, Jim van Os, Bart P F Rutten, Filip Smit, Lieuwe de Haan, Mark van der Gaag
Background: Child maltreatment has been associated with a wide range of mental disorders in adulthood. Whether child maltreatment is specifically associated with psychosis risk in individuals at ultra-high risk (UHR) for psychosis, or leads to a general vulnerability for overall psychopathology in the UHR stage remains unclear. The present study examines the association between child maltreatment and transition to psychosis and other mental disorders. Methods: The sample consisted of 259 UHR individuals from the EUropean network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) study...
June 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28662624/interference-between-family-caregivers-mental-disorders-and-their-estimates-of-quality-of-dying-and-death-qodd-of-their-loved-ones
#16
Maria Heckel, Sonja Bussmann, Martin Weber, Christoph Ostgathe, Stephanie Stiel
BACKGROUND: In studies enrolling informal caregivers of patients in palliative care, it is necessary to ensure that findings are not influenced by factors such as mental disorders. AIM: This study aims to describe the influence of anxiety and depression on bereaved informal caregivers' retrospective ratings of the quality of dying and death (QoDD) of their loved ones. DESIGN: Informal caregivers of deceased patients from 2 German palliative care (PC) units took part in a validation study of the German version of the original QoDD-Deutsch-Angehörige (QoDD-D-Ang) during the fourth week following the patient's death at the earliest...
January 2017: Journal of Palliative Care
https://www.readbyqxmd.com/read/28662619/dsm-5-diagnosis-of-internet-gaming-disorder-some-ways-forward-in-overcoming-issues-and-concerns-in-the-gaming-studies-field
#17
Daria J Kuss, Mark D Griffiths, Halley M Pontes
Background and aims The current DSM-5 diagnosis of Internet Gaming Disorder (IGD; American Psychiatric Association [APA], 2013) has led to a number of issues and concerns that we highlighted in our recent paper (Kuss, Griffiths, & Pontes, 2017). Experts in the field responded to our evaluation of these issues resulting in six commentaries. Methods In this paper, we offer responses to the six commentaries to move the scientific field forward. All of the responses to our original paper highlighted many conceptual, theoretical, and/or methodological problems with the proposed IGD diagnosis as outlined in the DSM-5...
June 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28661950/establishing-normative-data-for-pupillometer-assessment-in-neuroscience-intensive-care-the-end-panic-registry
#18
DaiWai M Olson, Sonja E Stutzman, Folefac Atem, Julia D Kincaide, Thuy-Tien Ho, Byron A Carlisle, Venkatesh Aiyagari
BACKGROUND: Trained medical practitioners have been assessing the pupillary light reflex for more than 2 millennia. However, the interrater reliability of the pupillary light reflex remains low. To overcome the drawbacks of a subjective interpretation of pupillary size and reactivity, automated pupillometers are becoming increasingly commonplace, but practitioners do not have adequate data from which to judge whether the numerical values provided by the pupillometer are "within reference limits...
August 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28659508/resolution-of-refractory-bipolar-disorder-with-psychotic-features-and-suicidality-through-lifestyle-interventions-a-case-report
#19
Kelly Brogan
Background • This case illustrates the relationship between gut, hormonal, and brain function in that dietary change, mindfulness interventions, and detoxification led to resolution of disabling luteally exacerbated psychiatric symptoms. Summary • A 45-y-old, married, Caucasian female with a history of diagnosed bipolar disorder with psychotic features, premenstrual dysphoric disorder, panic disorder, and repeated occurrence of suicide attempts and self-mutilating behavior presented for outpatient management...
April 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28659126/paroxysmal-freezing-of-gait-in-a-patient-with-mesial-frontal-transient-ischemic-attacks
#20
Hee Won Hwang, Seung Ha Lee, Chul Hyoung Lyoo, Myung Sik Lee
BACKGROUND: Rare patients have been reported who developed a mixture of gait disturbances following a focal lesion in the frontal lobe. Thus, the exact location of frontal lesion responsible for a specific gait disturbance is not well defined. CASE PRESENTATION: We describe a 47-year-old man who experienced two episodes of paroxysmal freezing of gait of the right leg. During the attacks, he had no motor weakness, sensory change, or disequilibrium. He had past history of panic attacks...
June 28, 2017: BMC Neurology
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