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https://www.readbyqxmd.com/read/28646603/comparison-of-oral-contrast-enhanced-transabdominal-ultrasound-imaging-with-transverse-contrast-enhanced-computed-tomography-in-preoperative-tumor-staging-of-advanced-gastric-carcinoma
#1
Xuemei He, Jing Sun, Xiaoling Huang, Chun Zeng, Yinggang Ge, Jun Zhang, Jingxian Wu
OBJECTIVES: This study assessed the diagnostic performance of transabdominal oral contrast-enhanced ultrasound (US) imaging for preoperative tumor staging of advanced gastric carcinoma by comparing it with transverse contrast-enhanced computed tomography (CT). METHODS: This retrospective study included 42 patients with advanced gastric cancer who underwent laparoscopy, radical surgery, or palliative surgery because of serious complications and had a body mass index of less than 25 kg/m(2) ...
June 24, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28645476/relation-of-coronary-artery-calcium-score-and-risk-of-cancer-from-a-danish-population-based-follow-up-study-in-patients-who-underwent-cardiac-computed-tomography
#2
Nicklas Vinter, Amanda M S Christesen, Leif S Mortensen, Jes S Lindholt, Søren P Johnsen, Anne Tjønneland, Lars Frost
Evidence of a causal link between atherosclerosis and cancer is sparse and conflicting. Therefore, we examined the association between extent of coronary atherosclerosis determined by coronary artery calcium score (CACS) and risk of cancer. We conducted a historical population-based cohort study of 28,549 cancer-free patients identified in the Western Denmark Heart Registry. All patients underwent cardiac computed tomography for measurement of CACS for suspected coronary artery disease. The outcome was an incident cancer diagnosis: total, tobacco-related, lung, prostate, breast, and colorectal...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28645267/a-rapid-and-quantitative-method-to-detect-human-circulating-tumor-cells-in-a-preclinical-animal-model
#3
Shih-Hsin Tu, Yi-Chen Hsieh, Li-Chi Huang, Chun-Yu Lin, Kai-Wen Hsu, Wen-Shyang Hsieh, Wei-Ming Chi, Chia-Hwa Lee
BACKGROUND: As cancer metastasis is the deadliest aspect of cancer, causing 90% of human deaths, evaluating the molecular mechanisms underlying this process is the major interest to those in the drug development field. Both therapeutic target identification and proof-of-concept experimentation in anti-cancer drug development require appropriate animal models, such as xenograft tumor transplantation in transgenic and knockout mice. In the progression of cancer metastasis, circulating tumor cells (CTCs) are the most critical factor in determining the prognosis of cancer patients...
June 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28642459/meta-analysis-of-soy-consumption-and-gastrointestinal-cancer-risk
#4
Demin Lu, Chi Pan, Chenyang Ye, Huijie Duan, Fei Xu, Li Yin, Wei Tian, Suzhan Zhang
Soy consumption has received considerable attention for its potential role in reducing cancer incidence and mortality. However, its effects on gastrointestinal (GI) cancer are controversial. Therefore, we performed a meta-analysis to evaluate the association between soy consumption and gastrointestinal cancer risk by searching for prospective studies in PubMed, Web of Science, EMBASE and the reference lists of the included articles. The study-specific odds ratio (OR), relative risk (RR) or hazard ratio (HR) estimates and 95% confidence intervals (CIs) were pooled using either a fixed-effect or random-effect model...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28640693/evaluation-of-screening-us-detected-breast-masses-by-combined-use-of-elastography-and-color-doppler-us-with-b-mode-us-in-women-with-dense-breasts-a-multicenter-prospective-study
#5
Su Hyun Lee, Jin Chung, Hye Young Choi, Seon Hyeong Choi, Eun Bi Ryu, Kyung Hee Ko, Hye Ryoung Koo, Jeong Seon Park, Ann Yi, Ji Hyun Youk, Eun Ju Son, A Jung Chu, Jung Min Chang, Nariya Cho, Myoung-Jin Jang, Shin Ho Kook, Eun Suk Cha, Woo Kyung Moon
Purpose To investigate the value of the combined use of elastography and color Doppler ultrasonography (US) with B-mode US for evaluation of screening US-detected breast masses in women with dense breasts. Materials and Methods This prospective, multicenter study included asymptomatic women with dense breasts who were referred for screening US between November 2013 and December 2014. Eligible women had a newly detected breast mass at conventional B-mode US screening, for which elastography and color Doppler US were performed...
June 21, 2017: Radiology
https://www.readbyqxmd.com/read/28640296/synthesis-and-photophysical-and-magnetic-studies-of-ternary-lanthanide-iii-complexes-of-naphthyl-chromophore-functionalized-imidazo-4-5-f-1-10-phenanthroline-and-dibenzoylmethane
#6
A Josephine Kanimozhi, V Alexander
The luminescent ternary lanthanide(iii) complexes [Ln(DBM)3(L1)] and [Ln(DBM)3(L2)] (Ln = Eu and Tb) of dibenzoylmethane (DBM) and 2-(2-naphthyl)-1H-imidazo[4,5-f][1,10]phenanthroline (L1) and 2-(2-hydroxy-1-naphthyl)-1H-imidazo[4,5-f][1,10]phenanthroline (L2) are reported in this work. The naphthyl chromophore functionalized imidazophenanthroline ligands L1 and L2 are structurally characterized by using single crystal X-ray diffraction: (L1), a = 14.933(4) Å, b = 7.4965(13) Å, c = 15.999(4) Å, α = γ = 90°, β = 102...
June 22, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28638453/the-clinical-impact-of-c-met-over-expression-in-advanced-biliary-tract-cancer-btc
#7
Mi Hwa Heo, Hee Kyung Kim, Hansang Lee, Kyoung-Mee Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park, Seung Tae Kim
Background: c-MET is a proto-oncogene that encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF). Activation of HGF-c-MET signaling involves cell invasiveness and evokes metastasis through direct involvement of tumor angiogenesis. However, the value of c-MET overexpression is still unknown in metastatic biliary tract cancer (BTC). Methods: We analyzed the incidence and clinicopathologic characteristics of c-MET overexpression in advanced BTC. Moreover, we investigated the value of c-MET overexpression in predicting response to gemicitabine plus cisplatin (GC), a first line standard regimen, and as a prognostic marker in metastatic BTC...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28634527/an-atypical-presentation-of-a-re-emerging-disease
#8
Michael Hunter, Patrick Brine
Often referred to as 'The Great Mimicker', syphilis infections have been on the rise since 2000 including cases of primary and secondary syphilis where 19,999 were reported in the USA in 2014. ​​The increase in cases has led the USPSTF to recommend screening for syphilis infection in persons who are at increased risk of infection. ​​Changes in screening and re-emergence of the disease necessitates review of the multitude of circumstances a patient can present for care. Immunocompetent patients begin to show classic symptoms within 10-90 days following infection with the spirochete...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28634067/magnetic-graphene-coated-inorganic-organic-hybrid-nanocomposite-for-enhanced-preconcentration-of-selected-pesticides-in-tomato-and-grape
#9
Hamid Rashidi Nodeh, Hassan Sereshti, Hamid Gaikani, Muhammad Afzal Kamboh, Zahra Afsharsaveh
The new magnetic graphene based hybrid silica-N-[3-(trimethoxysilyl)propyl]ethylenediamine (MG@SiO2-TMSPED) nanocomposite was synthesized via sol-gel process, and used as an effective adsorbent in magnetic solid phase extraction (MSPE) of three selected pesticides followed by gas chromatography micro-electron capture detection (GC-μECD). The adsorbent was characterized using Fourier transform-infrared spectroscopy (FT-IR), Brunauer-Emmett-Teller (BET), Barrett-Joyner-Halenda (BJH), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDXS) techniques...
June 13, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28632255/intake-of-proton-pump-inhibitors-is-associated-with-an-increased-risk-of-dental-implant-failure
#10
Bruno Ramos Chrcanovic, Jenö Kisch, Tomas Albrektsson, Ann Wennerberg
PURPOSE: To investigate the association between the intake of proton pump inhibitors (PPIs) and the risk of dental implant failure. MATERIALS AND METHODS: The present retrospective cohort study is based on patients consecutively treated between 1980 and 2014 with implant-supported/retained prostheses at one specialist clinic. Modern endosseous dental implants with cylindrical or conical design were included, and only complete cases were considered; ie, only those implants with information available for all variables measured were included in the regression model analysis...
June 20, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28629554/emphysema-quantification-and-lung-volumetry-in-chest-x-ray-equivalent-ultralow-dose-ct-intra-individual-comparison-with-standard-dose-ct
#11
Michael Messerli, Thorsten Ottilinger, René Warschkow, Sebastian Leschka, Hatem Alkadhi, Simon Wildermuth, Ralf W Bauer
OBJECTIVES: To determine whether ultralow dose chest CT with tin filtration can be used for emphysema quantification and lung volumetry and to assess differences in emphysema measurements and lung volume between standard dose and ultralow dose CT scans using advanced modeled iterative reconstruction (ADMIRE). METHODS: 84 consecutive patients from a prospective, IRB-approved single-center study were included and underwent clinically indicated standard dose chest CT (1...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28627450/impact-of-fixation-artifacts-and-threshold-selection-on-high-resolution-melting-analysis-for-kras-mutation-screening
#12
Wendy Pérez-Báez, Ethel A Garcia-Latorre, Hector Aquiles Maldonado-Martinez, Iris Coronado-Martinez, Leonardo Flores-Garcia, Lucía Taja-Chayeb
INTRODUCTION: Treatment in the metastatic colorectal cancer has expanded with monoclonal antibodies targeting Epidermal Growth Factor Receptor, but is restricted to patients with a wild-type (WT) KRAS mutational status. The most sensitive assays for KRAS mutation detection in formalin-fixed paraffin embedded (FFPE) tissues are based on Real-time PCR. Among them, high resolution melting analysis (HRMA), is a simple, fast, highly sensitive, specific and cost-effective method, proposed as adjunct for KRAS mutation detection...
June 13, 2017: Molecular and Cellular Probes
https://www.readbyqxmd.com/read/28625376/electrocardiographic-abnormalities-and-mortality-in-aging-survivors-of-childhood-cancer-a-report-from-the-st-jude-lifetime-cohort-study
#13
Daniel A Mulrooney, Elsayed Z Soliman, Matthew J Ehrhardt, Lu Lu, Daniel A Duprez, Russell V Luepker, Gregory T Armstrong, Vijaya M Joshi, Daniel M Green, Deokumar Srivastava, Matthew J Krasin, G Stephen Morris, Leslie L Robison, Melissa M Hudson, Kirsten K Ness
BACKGROUND: Electrocardiography (ECG), predictive of adverse outcomes in the general population, has not been studied in cancer survivors. We evaluated the prevalence of ECG abnormalities and associations with mortality among childhood cancer survivors. METHODS: Major and minor abnormalities were coded per the Minnesota Classification system for participants in the St Jude Lifetime Cohort Study (n = 2,715) and community controls (n = 268). Odds ratios (ORs) and 95% CIs were calculated using multivariable logistic regression; and hazard ratios, using Cox proportional hazards regression...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28625236/-eosinophil-could-predict-the-prognosis-of-patients-with-bloodstream-infection-a-retrospective-analysis-of-305-cases
#14
Duan Guo, Chao Jia, Hang Su
OBJECTIVE: To investigate the value of peripheral blood for the prognosis of patients with bloodstream infection. METHODS: A retrospective analysis of patients with bloodstream infection was conducted in the intensive care unit (ICU) of Mianyang Central Hospital of Sichuan from January 2012 to October 2016. According to the 28-day survival, the patients were divided into survival group and death group. The white blood cell (WBC), neutrophils count (NEU), lymphocyte count (LYM), neutrophil/lymphocyte ratio (NLR), monocyte count (MO), eosinophil count (EO), basophil count (BA), hemoglobin (Hb), platelet count (PLT) and procalcitonin (PCT) in peripheral blood were recorded when patients were diagnosed with blood infection...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28624816/circulating-micrornas-as-potential-biomarkers-for-coronary-plaque-rupture
#15
Sufang Li, Chongyou Lee, Junxian Song, Changlin Lu, Jun Liu, Yuxia Cui, Huizhu Liang, Chengfu Cao, Feng Zhang, Hong Chen
Coronary plaque rupture is the most common cause of acute coronary syndrome. However, the timely biomarker-based diagnosis of plaque rupture remains a major unmet clinical challenge. Balloon dilatation and stent implantation during percutaneous coronary intervention (PCI) could cause plaque injury and rupture. Here we aimed to assess the possibility of circulating microRNAs (miRNAs) as biomarkers of acute coronary plaque rupture by virtue of the natural model of PCI-induced plaque rupture. Stable coronary artery disease patients underwent PCI with single stent implantation were recruited and a three-phase approach was conducted in the present study: (i) profiling of plasma miRNAs in a group of patients before (0 h) and after balloon dilatation for 1 h (1 h vs...
May 30, 2017: Oncotarget
https://www.readbyqxmd.com/read/28624400/left-ventricular-geometry-determines-prognosis-and-reverse-j-shaped-relation-between-blood-pressure-and-mortality-in-ischemic-stroke-patients
#16
Chan Soon Park, Jun-Bean Park, Yerim Kim, Yeonyee E Yoon, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Goo-Yeong Cho, Dae-Won Sohn, Seung-Hoon Lee
OBJECTIVES: This study sought to investigate the prognostic significance of left ventricular (LV) mass and geometry in ischemic stroke survivors, as well as the LV geometry-specific differences in the blood pressure-mortality relationship. BACKGROUND: LV mass and geometry are well-known prognostic factors in various populations; however, there are no data on their role in ischemic stroke patients. METHODS: We prospectively recruited 2,328 consecutive patients admitted with acute ischemic stroke to our institute between 2002 and 2010...
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28619006/tag-snp-selection-for-prediction-of-tick-resistance-in-brazilian-braford-and-hereford-cattle-breeds-using-bayesian-methods
#17
Bruna P Sollero, Vinícius S Junqueira, Cláudia C G Gomes, Alexandre R Caetano, Fernando F Cardoso
BACKGROUND: Cattle resistance to ticks is known to be under genetic control with a complex biological mechanism within and among breeds. Our aim was to identify genomic segments and tag single nucleotide polymorphisms (SNPs) associated with tick-resistance in Hereford and Braford cattle. The predictive performance of a very low-density tag SNP panel was estimated and compared with results obtained with a 50 K SNP dataset. RESULTS: BayesB (π = 0.99) was initially applied in a genome-wide association study (GWAS) for this complex trait by using deregressed estimated breeding values for tick counts and 41,045 SNP genotypes from 3455 animals raised in southern Brazil...
June 15, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/28618060/clinical-validation-of-the-nursing-diagnosis-of-ineffective-protection-in-hemodialysis-patients
#18
Jéssica Dantas de Sá Tinôco, Maria das Graças Mariano Nunes de Paiva, Cecília Maria Farias de Queiroz Frazão, Kadyjina Daiane Batista Lucio, Maria Isabel da Conceição Dias Fernandes, Marcos Venicios de Oliveira Lopes, Ana Luisa Brandão de Carvalho Lira
AIMS AND OBJECTIVES: The aim of this study was to evaluate the clinical validity of indicators of the nursing diagnosis of "ineffective protection" in hemodialysis patients. BACKGROUND: Hemodialysis patients have reduced protection. Studies on the nursing diagnosis of "ineffective protection" are scarce in the literature. The use of indicators to diagnose "ineffective protection" could improve the care of hemodialysis patients. The clinical usefulness of the indicators requires clinical validation...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28615900/predictors-of-outcome-in-children-with-status-epilepticus-during-resuscitation-in-pediatric-emergency-department-a-retrospective-observational-study
#19
Indumathy Santhanam, Sangeetha Yoganathan, V Akila Sivakumar, Rubini Ramakrishnamurugan, Sharada Sathish, Murali Thandavarayan
OBJECTIVES: To study the clinical profile and predictors of outcome in children with status epilepticus (SE) during resuscitation in pediatric emergency department. MATERIALS AND METHODS: This retrospective study was carried out in a tertiary care teaching hospital. Admission and resuscitation data of children, aged between 1 month and 12 years, treated for SE, between September 2013 and August 2014, were extracted using a standard data collection form. Our SE management protocol had employed a modified pediatric assessment triangle to recognize and treat acute respiratory failure, cardiovascular dysfunction (CD), and subtle SE until all parameters resolved...
April 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28614286/three-dimensional-true-spine-length-a-novel-technique-for-assessing-the-outcomes-of-scoliosis-surgery
#20
Alan J Spurway, Jennifer K Hurry, Luke Gauthier, Ben Orlik, Chukwudi K Chukwunyerenwa, Waleed E Kishta, Ron El-Hawary
BACKGROUND: Current assessment of spine growth for patients undergoing growth friendly surgical treatment for early-onset scoliosis (EOS) is the use of serial, 1-dimensional standard-of-care coronal vertical spine height (SoCVH) measurements. Any growth of the spine out of the coronal plane is missed by the SoCVH, which may underestimate the actual growth of the spine. This study set to validate the novel 3-dimensional true spine length (3DTSL) radiographic measurement technique for measuring growth of EOS patients...
June 13, 2017: Journal of Pediatric Orthopedics
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