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https://www.readbyqxmd.com/read/28206793/do-positive-spontaneous-thoughts-function-as-incentive-salience
#1
Elise L Rice, Barbara L Fredrickson
The present work explores the theoretical relationship between positive spontaneous thoughts and incentive salience-a psychological property thought to energize wanting and approach motivation by rendering cues that are associated with enjoyment more likely to stand out to the individual when subsequently encountered in the environment (Berridge, 2007). We reasoned that positive spontaneous thoughts may at least be concomitants of incentive salience, and as such, they might likewise mediate the effect of liking on wanting...
February 16, 2017: Emotion
https://www.readbyqxmd.com/read/28199904/cyclic-electron-flow-may-provide-some-protection-against-psii-photoinhibition-in-rice-oryza-sativa-l-leaves-under-heat-stress
#2
Jemaa Essemine, Yi Xiao, Mingnan Qu, Hualing Mi, Xin-Guang Zhu
Previously we have shown that a quick down-regulation in PSI activity compares to that of PSII following short-term heat stress for two rice groups including C4023 and Q4149, studied herein. These accessions were identified to have different natural capacities in driving cyclic electron flow (CEF) around PSI; i.e., low CEF (lcef) and high CEF (hcef) for C4023 and Q4149, respectively. The aim of this study was to investigate whether these two lines have different mechanisms of protecting photosystem II from photodamage under heat stress...
January 30, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28188726/the-roles-of-v-type-h-atpase-and-na-k-atpase-in-energizing-k-and-h-transport-in-larval-drosophila-gut-epithelia
#3
Natalie M D'Silva, Andrew Donini, Michael J O'Donnell
We analyzed V-type H(+)-ATPase (VA) and Na(+)/K(+)-ATPase (NKA) along the caeca and midgut of third instar Drosophila larvae using immunohistochemistry and ATPase activity assays. Corresponding H(+) and K(+) fluxes were characterized using the Scanning Ion-Selective Electrode Technique (SIET), and the roles of transport ATPases in energizing ion transport across the larval gut were investigated by basal application of bafilomycin, a VA inhibitor, and ouabain, a NKA inhibitor. Addition of bafilomycin led to a decrease in H(+) absorption along the caeca and midgut except at the copper cells and large flat cell zone of the middle midgut...
February 7, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28167264/surface-modified-particles-loaded-with-camkii-inhibitor-protect-cardiac-cells-against-mitochondrial-injury
#4
Amaraporn Wongrakpanich, Angie S Morris, Sean M Geary, Mei-Ling A Joiner, Aliasger K Salem
An excess of calcium (Ca(2+)) influx into mitochondria during mitochondrial re-energization is one of the causes of myocardial cell death during ischemic/reperfusion injury. This overload of Ca(2+) triggers the mitochondrial permeability transition pore (mPTP) opening which leads to programmed cell death. During the ischemic/reperfusion stage, the activated Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) enzyme is responsible for Ca(2+) influx. To reduce CaMKII-related cell death, sub-micron particles composed of poly(lactic-co-glycolic acid) (PLGA), loaded with a CaMKII inhibitor peptide were fabricated...
February 3, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28135573/retinal-venous-blood-carbon-monoxide-response-to-bright-light-in-male-pigs-a-preliminary-study
#5
Dan A Oren, Magdalena Duda, Katarzyna Kozioł, Maria Romerowicz-Misielak, Anna Koziorowska, Przemysław Sołek, Sławomir Nowak, Magdalena Kulpa, Marek Koziorowski
The physical mechanism by which light is absorbed in the eye and has antidepressant and energizing effects in Seasonal Affective Disorder and other forms of psychiatric major depression is of scientific interest. This study was designed to explore one specific aspect of a proposed humoral phototransduction mechanism, namely that carbon monoxide (CO) levels increase in retinal venous blood in response to bright light. Eleven mature male pigs approximately six months of age were kept for 7days in darkness and fasted for 12h prior to surgery...
January 21, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28132008/compensatory-changes-in-energy-balance-during-dapagliflozin-treatment-in-type-2-diabetes-mellitus-a-randomised-double-blind-placebo-controlled-cross-over-trial-energize-study-protocol
#6
Surya Panicker Rajeev, Victoria S Sprung, Carl Roberts, Jo A Harrold, Jason C G Halford, Andrej Stancak, Emma J Boyland, Graham J Kemp, Daniel J Cuthbertson, John P H Wilding
INTRODUCTION: Sodium glucose cotransporter 2 (SGLT2) inhibitors are effective blood-glucose-lowering medications with beneficial effects on body weight in patients with type 2 diabetes mellitus (T2DM). However, observed weight loss is less than that predicted from quantified glycosuria, suggesting a compensatory increase in energy intake or a decrease in energy expenditure. Studies using dual-energy X-ray absorptiometry (DEXA) have suggested most body weight change is due to loss of adipose tissue, but organ-specific changes in fat content (eg, liver, skeletal muscle) have not been determined...
January 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28131145/preferred-methods-of-learning-for-nursing-students-in-an-on-line-degree-program
#7
Debra Hampton, Patricia F Pearce, Debra K Moser
Investigators have demonstrated that on-line courses result in effective learning outcomes, but limited information has been published related to preferred teaching strategies. Delivery of on-line courses requires various teaching methods to facilitate interaction between students, content, and technology. The purposes of this study were to understand student teaching/learning preferences in on-line courses to include (a) differences in preferred teaching/learning methods for on-line nursing students across generations and (b) which teaching strategies students found to be most engaging and effective...
January 2017: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/28125491/executive-summary-transforming-moral-distress-into-moral-resilience-in-nursing
#8
Cynda Hylton Rushton, Kathy Schoonover-Shoffner, Maureen Shawn Kennedy
: To examine practices for addressing moral distress, a collaborative project was developed by the Johns Hopkins Berman Institute of Bioethics, the Johns Hopkins School of Nursing, the American Journal of Nursing, and the Journal of Christian Nursing, along with the American Association of Critical-Care Nurses and the American Nurses Association. Its purpose was to identify strategies that individuals and systems can use to mitigate the detrimental effects of moral distress and foster moral resilience. On August 11 and 12, 2016, an invitational symposium, State of the Science: Transforming Moral Distress into Moral Resilience in Nursing, was held at the Johns Hopkins School of Nursing in Baltimore, Maryland...
February 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28119519/supercapacitors-porous-materials-get-energized
#9
Alexandru Vlad, Andrea Balducci
No abstract text is available yet for this article.
January 25, 2017: Nature Materials
https://www.readbyqxmd.com/read/28106310/mechanism-of-type-iii-protein-secretion-regulation-of-flha-conformation-by-a-functionally-critical-charged-residue-cluster
#10
Marc Erhardt, Paige Wheatley, Eun A Kim, Takanori Hirano, Yang Zhang, Mayukh K Sarkar, Kelly T Hughes, David F Blair
The bacterial flagellum contains a specialized secretion apparatus in its base that pumps certain protein subunits through the growing structure to their sites of installation beyond the membrane. A related apparatus functions in the injectisomes of gram-negative pathogens to export virulence factors into host cells. This mode of protein export is termed type-III secretion (T3S). Details of the T3S mechanism are unclear. It is energized by the proton gradient; here, a mutational approach was used to identify proton-binding groups that might function in transport...
January 20, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28098416/motuporamine-derivatives-as-antimicrobial-agents-and-antibiotic-enhancers-against-resistant-gram-negative-bacteria
#11
Diane Borselli, Marine Blanchet, Jean-Michel Bolla, Aaron Muth, Kristen Skruber, Otto Phanstiel, Jean Michel Brunel
Dihydromotuporamine C and its derivatives were evaluated for their in vitro antimicrobial activities and antibiotic enhancement properties against Gram-negative bacteria and clinical isolates. The mechanism of action of one of these derivatives, MOTU-N44, was investigated against Enterobacter aerogenes by using fluorescent dyes to evaluate outer-membrane depolarization and permeabilization. Its efficiency correlated with inhibition of dye transport, thus suggesting that these molecules inhibit drug transporters by de-energization of the efflux pump rather than by direct interaction of the molecule with the pump...
February 1, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28079288/surface-enhanced-raman-spectra-promoted-by-a-finger-press-in-an-all-solid-state-flexible-energy-conversion-and-storage-film
#12
Haitao Li, Han Dai, Yihe Zhang, Wangshu Tong, Hua Gao, Qi An
Electrochemically up-regulated surface-enhanced Raman spectroscopy (E-SERS) effectively increases Raman signal intensities. However, the instrumental requirements and the conventional measurement conditions in an electrolyte cell have hampered its application in fast and on-site detection. To circumvent the inconveniences of E-SERS, we propose a self-energizing substrate that provides electrical potential by converting film deformation from a finger press into stored electrical energy. The substrate combines an energy conversion film and a SERS-active Ag nanowire layer...
March 1, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28076263/-a-paradox-persists-when-the-paradigm-is-wrong-pisacano-scholars-reflections-from-the-inaugural-starfield-summit
#13
Noemi Doohan, Anastasia J Coutinho, Jennifer Lochner, Diana Wohler, Jennifer DeVoe
The inaugural Starfield Summit was hosted in April 2016 by the Robert Graham Center for Policy Studies in Family Medicine and Primary Care with additional partners and sponsors, including the Pisacano Leadership Foundation (PLF). The Summit addressed critical topics in primary care and health care delivery, including payment, measurement, and team-based care. Invited participants included an interdisciplinary group of pediatricians, family physicians, internists, behaviorists, trainees, researchers, and advocates...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28013504/macromolecule-biosynthesis-assay-and-fluorescence-spectroscopy-methods-to-explore-antimicrobial-peptide-mode-s-of-action
#14
Bimal Jana, Kristin Renee Baker, Luca Guardabassi
Antimicrobial peptides (AMPs) are viable alternatives to the currently available antimicrobials, and numerous studies have investigated their possible use as therapeutic agents for specific clinical applications. AMPs are a diverse class of antimicrobials that often act upon the bacterial cell membrane but may exhibit additional modes of action. Identification of the multiple modes of action requires a comprehensive study at subinhibitory concentrations and careful data analysis since additional modes of action can be eclipsed by AMP action on the cell membrane...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28011846/two-distinct-membrane-potential-dependent-steps-drive-mitochondrial-matrix-protein-translocation
#15
Alexander Benjamin Schendzielorz, Christian Schulz, Oleksandr Lytovchenko, Anne Clancy, Bernard Guiard, Raffaele Ieva, Martin van der Laan, Peter Rehling
Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is considered to drive translocation of positively charged presequences through the TIM23 complex (presequence translocase), the activity of the Hsp70-powered import motor is crucial for the translocation of the mature protein portion into the matrix. In this study, we show that mitochondrial matrix proteins display surprisingly different dependencies on the Δψ. However, a precursor's hypersensitivity to a reduction of the Δψ is not linked to the respective presequence, but rather to the mature portion of the polypeptide chain...
January 2, 2017: Journal of Cell Biology
https://www.readbyqxmd.com/read/28007968/nitrite-protects-mitochondrial-structure-and-function-under-hypoxia
#16
Kapuganti Jagadis Gupta, Chun Pong Lee, R George Ratcliffe
Oxygen deprivation leads to changes in mitochondrial morphology and impaired flow of reducing equivalents through the electron transport chain. The extent of these changes depends on the duration and severity of the treatment as well as on the species and cell type. Nitrate is known to ameliorate these effects in some instances, but it is possible that it is nitrite, rather than nitrate, that is the key to the mechanism. To test this, mitochondria were isolated from 21-day-old pea (Pisum sativum) roots and incubated for 90 min under normoxia or hypoxia in the presence or absence of 0...
October 25, 2016: Plant & Cell Physiology
https://www.readbyqxmd.com/read/27991824/symbolic-meanings-of-sex-in-relationships-developing-the-meanings-of-sexual-behavior-inventory
#17
Amanda M Shaw, Ronald D Rogge
Consistent with symbolic interactionism and motivation research, the study explored the meanings of sexual behavior in romantic relationships in a sample of 3,003 online respondents. Starting with a pool of 104 respondent-generated items, Exploratory and Confirmatory Factor analyses in separate sample halves revealed a stable set of 9 dimensions within that item pool that formed 2 higher-order factors representing positive (to share pleasure, to bond, to de-stress, to energize the relationship, to learn more about each other) and negative (to manage conflict, as an incentive, to express anger, and to control partner) meanings of sexual behavior within relationships...
December 19, 2016: Psychological Assessment
https://www.readbyqxmd.com/read/27986867/sucrose-transporter-localization-and-function-in-phloem-unloading-in-developing-stems
#18
Ricky J Milne, Jai M Perroux, Anne L Rae, Anke Reinders, John M Ward, Christina E Offler, John W Patrick, Christopher P L Grof
How sucrose transporters (SUTs) regulate phloem unloading in monocot stems is poorly understood and particularly so for species storing high Suc concentrations. To this end, Sorghum bicolor SUTs SbSUT1 and SbSUT5 were characterized by determining their transport properties heterologously expressed in yeast or Xenopus laevis oocytes, and their in planta cellular and subcellular localization. The plasma membrane-localized SbSUT1 and SbSUT5 exhibited a strong selectivity for Suc and high Suc affinities in X. laevis oocytes at pH 5-SbSUT1, 6...
February 2017: Plant Physiology
https://www.readbyqxmd.com/read/27970230/tct-839-acute-safety-and-technical-performance-evaluation-of-a-novel-cto-crossing-device-based-on-a-shock-wave-energized-guidewire
#19
Louis-Philippe Riel, Manuel Charlebois-Ménard, Steven Dion, Stéphane Rinfret, Jean-Franà Ois Tanguay, Marie-Élaine Clavet, Marie-Jeanne Bertrand, Pascale Geoffroy, Simon Berube, Marc-Antoine Despatis, Marianne Brodmann, Éric Thérèse, Andrew Benko, Louis-Georges Guy, Guy LeClerc, Madeleine Chagnon, Martin Brouillette
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27967187/multispecies-plasma-expansion-into-vacuum-the-role-of-secondary-ions-and-suprathermal-electrons
#20
I S Elkamash, I Kourakis
The self-similar expansion of multispecies ion plasma is investigated by a two-ion fluid model with adiabatic equation of state for each ionic species. Our aim is to elucidate the effect of secondary ions on a plasma expansion front, in combination with energetic (suprathermal) electrons in the background, modeled by a kappa-type distribution function. The plasma density, velocity, and electric-field profile is investigated. It is shown that energetic electrons have a significant effect on the expansion front dynamics, essentially energizing the front, thus enhancing the ion acceleration mechanism...
November 2016: Physical Review. E
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