keyword
https://read.qxmd.com/read/38528456/roar-a-re-optimization-based-online-adaptive-radiotherapy-of-anal-cancer-a-prospective-phase-ii-trial-protocol
#21
JOURNAL ARTICLE
Katrine Smedegaard Storm, Lina M Åström, Patrik Sibolt, Claus P Behrens, Gitte F Persson, Eva Serup-Hansen
BACKGROUND: Chemo-radiotherapy with curative intent for anal cancer has high complete remission rates, but acute treatment-related gastrointestinal (GI) toxicity is significant. Toxicity occurs due to irradiation of surrounding normal tissue. Current radiotherapy requires the addition of large planning margins to the radiation field to ensure target coverage regardless of the considerable organ motion in the pelvic region. This increases the irradiated volume and radiation dose to the surrounding normal tissue and thereby toxicity...
March 25, 2024: BMC Cancer
https://read.qxmd.com/read/38527373/an-updated-variable-rbe-model-for-proton-therapy
#22
JOURNAL ARTICLE
Erlend Lyngholm, Camilla Hanqvuist Stokkevåg, Armin Lühr, Liheng Tian, Ilker Meric, Johannes Tjelta, Helge Henjum, Andreas Havsgård Handeland, Kristian Smeland Ytre-Hauge
Objective. While a constant relative biological effectiveness (RBE) of 1.1 forms the basis for clinical proton therapy, variable RBE models are increasingly being used in plan evaluation. However, there is substantial variation across RBE models, and several new in vitro datasets have not yet been included in the existing models. In this study, an updated in vitro proton RBE database was collected and used to examine current RBE model assumptions, and to propose an up-to-date RBE model as a tool for evaluating RBE effects in clinical settings...
March 25, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38527341/the-impact-of-radiation-on-nipple-symmetry-after-bilateral-nipple-sparing-mastectomy-and-implant-based-reconstruction-an-objective-analysis
#23
JOURNAL ARTICLE
Ciara A Brown, Grant W Carlson
INTRODUCTION: Radiation therapy can adversely affect outcomes of implant-based breast reconstruction, potentially complicating procedures like nipple-sparing mastectomy (NSM), which is increasingly popular in breast cancer management. This study aims to evaluate the impact of radiation on nipple symmetry in patients undergoing bilateral NSM with implant-based reconstruction. METHODS: We conducted a retrospective analysis using data from an Emory University review board-approved database...
April 1, 2024: Annals of Plastic Surgery
https://read.qxmd.com/read/38527175/estimation-of-internal-exposure-contribution-in-radiation-dose-exposure-for-boron-neutron-capture-therapy
#24
JOURNAL ARTICLE
Ryosuke Narita, Yoshinori Sakurai
Although boron neutron capture therapy (BNCT) causes minor damage to normal cells owing to the nuclear reactions induced by neutrons with major elements of tissues such as hydrogen and nitrogen, it is useful to estimate the accurate exposure dose for radiation protection. This study aims to estimate the contribution of internal exposure in radiation exposure dose for BNCT. The study was performed by referring to clinical studies at a reactor-based BNCT facility on the basis of computational dosimetry. Five irradiation regions of head and neck were selected for the estimation...
March 25, 2024: Radiation Protection Dosimetry
https://read.qxmd.com/read/38526691/optimizing-precision-rhinoplasty-comprehensive-preoperative-planning-with-nasal-computed-tomography-for-functional-and-aesthetic-enhancement
#25
JOURNAL ARTICLE
Pawel Szychta
BACKGROUND: The evolving field of rhinoplasty increasingly recognizes the importance of clinical expertise over routine preoperative nasal computed tomography (CT) for planning surgical interventions. This study evaluates the clinical utility of preoperative nasal CT in enhancing the precision of open structured rhinoplasty, focusing on both functional and aesthetic outcomes without compromising patient safety through unnecessary radiation exposure. The study aimed to assess the impact of preoperative nasal CT on surgical planning and intraoperative maneuvers...
March 25, 2024: Maxillofacial Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38522866/left-ventricular-outflow-tract-obstruction-in-congenital-heart-disease-the-role-of-cardiovascular-computed-tomography-in-surgical-decision-making
#26
REVIEW
B Kelly Han, Edem Binka, Eric Griffiths, Reilly Hobbs, Aaron Eckhauser, Adil Husain, David Overman
Patients with many forms of congenital heart disease (CHD) and hypertrophic cardiomyopathy undergo surgical intervention to relieve left ventricular outflow tract obstruction (LVOTO). Cardiovascular Computed Tomography (CCT) defines the complex pathway from the ventricle to the outflow tract and can be visualized in 2D, 3D, and 4D (3D in motion) to help define the mechanism and physiologic significance of obstruction. Advanced cardiac visualization may aid in surgical planning to relieve obstruction in the left ventricular outflow tract, aortic or neo-aortic valve and the supravalvular space...
2024: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://read.qxmd.com/read/38522504/robotic-assisted-uterine-transposition-followed-by-anatomic-pelvic-repositioning-for-a-patient-with-intramural-fibroids-and-rectal-cancer
#27
JOURNAL ARTICLE
Megan E Gornet, Mindy S Christianson, Rebecca L Stone
OBJECTIVE: To report the first described case of robotic-assisted utero-ovarian transposition followed by anatomic repositioning in the pelvis and cervico-vaginal anastomosis in a woman with uterine fibroids, which was performed for fertility preservation in the context of pelvic radiation for rectal cancer. DESIGN: Description of technique and live-action narrated surgical footage showing uterine transposition and repositioning. SUBJECT(S): 36 year-old woman with a new diagnosis of cT3N2M0 rectal adenocarcinoma, planned for neoadjuvant chemotherapy and pelvic radiation, who desired fertility preservation permissive of future pregnancy...
March 22, 2024: Fertility and Sterility
https://read.qxmd.com/read/38521132/long-term-outcomes-after-concurrent-once-or-twice-daily-chemoradiation-in-limited-stage-small-cell-lung-cancer-a-brief-report-from-the-convert-trial
#28
EDITORIAL
Gerard M Walls, Hitesh Mistry, Fabrice Barlesi, Andrea Bezjak, Cecile Le Pechoux, Mary O'Brien, Jan P Van Meerbeeck, Fiona Blackhall, Corinne Faivre-Finn
INTRODUCTION: CONVERT was a phase 3 international randomized clinical trial comparing once-daily (OD) and twice-daily (BD) radiation therapy (RT). This updated analysis describes the 6.5 year outcomes of these regimes delivered with conformal techniques. METHODS: CONVERT (NCT00433563) randomized patients 1:1 between OD RT (66 Gy/33 fractions/6.5 weeks) and BD RT (45 Gy/30 fractions/3 weeks) both delivered with concurrent cisplatin/etoposide. Three-dimensional conformal RT was mandatory, intensity-modulated RT was permitted, and elective nodal irradiation was not allowed...
March 11, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38520859/assessment-of-land-use-land-cover-change-derived-catchment-hydrologic-response-an-integrated-parsimonious-hydrological-modeling-and-alteration-analysis-based-approach
#29
JOURNAL ARTICLE
Sonam Sandeep Dash, Bijayalaxmi Naik, Pradeep Singh Kashyap
Land use/land cover (LULC) change, often a consequence of natural or anthropogenic drivers, plays a decisive role in governing global catchment dynamics, and subsequent impact on regional hydrology. Insight into the complex relationship between the drivers of LULC change and catchment hydrology is of utmost importance to decision makers. Contemplating the dynamic rainfall-runoff response of the Indian catchments, this study proposes an integrated modeling-based approach to identify the drivers and relative contribution to catchment hydrology...
March 22, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38520072/acr-benchmark-testing-of-a-novel-high-speed-ring-gantry-linac-kv-cbct-system
#30
JOURNAL ARTICLE
Allison Haertter, Michael Salerno, Brandon Koger, Christopher Kennedy, Michelle Alonso-Basanta, Lei Dong, Boon-Keng Teo, Taoran Li
A new generation cone-beam computed tomography (CBCT) system with new hardware design and advanced image reconstruction algorithms is available for radiation treatment simulation or adaptive radiotherapy (HyperSight CBCT imaging solution, Varian Medical Systems-a Siemens Healthineers company). This study assesses the CBCT image quality metrics using the criteria routinely used for diagnostic CT scanner accreditation as a first step towards the future use of HyperSight CBCT images for treatment planning and target/organ delineations...
March 22, 2024: Journal of Applied Clinical Medical Physics
https://read.qxmd.com/read/38519351/can-an-in-person-hands-on-applicator-based-teaching-session-improve-trainee-knowledge-and-comfort-with-complex-gynecologic-brachytherapy
#31
JOURNAL ARTICLE
Abigail Groszkiewicz, Emily Foust, Brett Palestra, Michelle C Ertel, Michelle Boisen, Paniti Sukumvanich, Shannon Kroskie Smith, Ryan P Smith, John A Vargo
INTRODUCTION: With the emergence of imaged-based planning and hybrid applicators the complexity of gynecologic brachytherapy has dramatically increased. Despite the known advantages of brachytherapy, notable national declines in utilization of brachytherapy have been documented. Clearly improved education in the sphere of gynecologic brachytherapy is needed. We hypothesize that a hands-on applicator-based training session would improve trainee comfort with gynecologic brachytherapy. METHODS AND MATERIALS: An in-person, applicator-based, hands-on training session was held with trainees from both radiation and gynecologic oncology programs...
March 21, 2024: Brachytherapy
https://read.qxmd.com/read/38518660/is-my-patient-an-appropriate-candidate-for-sentinel-node-biopsy-less-axillary-surgery-for-the-right-patients-critical-review-and-grades-of-recommendation
#32
REVIEW
Jordana de Faria Bessa, Guilherme Garcia Novita, Laura Testa, Ruffo Freitas-Junior, Gustavo Nader Marta
INTRODUCTION: While general conclusions of historical trials are widely recognized, the nuances regarding precise indications of Sentinel Node Biopsy (SNB) in breast cancer in complex clinical scenarios often remain a source of debate and require further elucidation. METHODS: Two reviewers (JFB and GNM) independently searched electronic databases for studies including SNB as the main intervention. Filters were applied to retrieve only clinical trials (randomized or experimental non-randomized); non-oncological outcomes were excluded...
March 15, 2024: Surgical Oncology
https://read.qxmd.com/read/38518555/radiation-therapy-oncology-group-8502-quad-shot-regimen-using-volumetric-modulated-arc-therapy-for-incurable-head-and-neck-cancer
#33
JOURNAL ARTICLE
Ryo Toya, Yoshiyuki Fukugawa, Tetsuo Saito, Tomohiko Matsuyama, Ryoji Yoshida, Daizo Murakami, Yorihisa Orita, Hideki Nakayama, Natsuo Oya
OBJECTIVES: We aimed to evaluate the outcomes of the Radiation Therapy Oncology Group 8502 "QUAD shot" regimen using volumetric modulated arc therapy (VMAT) for incurable head and neck cancer (HNC). MATERIALS AND METHODS: We included 105 patients with HNC in the study, undergoing at least one QUAD shot regimen cycle. We planned the radiotherapy using VMAT with 6 MV photons. One QUAD shot cycle included 14.8 Gy in 4 fractions with at least 6-hour intervals over 2 consecutive days, repeated every 3-6 weeks up to 3 cycles...
March 21, 2024: Oral Oncology
https://read.qxmd.com/read/38518360/gate-monte-carlo-approach-to-heterogeneity-dose-distribution-in-small-fields-used-in-radiation-therapy
#34
JOURNAL ARTICLE
Zakaria Ait Elcadi, Mostafa El Moussaoui, Souha Aouadi, Renilmon Sukurmaran, Rabih Hammoud, Noora Al-Hammadi, Yassine Toufique, Othmane Bouhali
The Accurate dosage prediction in Radiation Therapy is challenging, prompting a need for precision beyond conventional clinical Treatment Planning Systems (TPS). Monte Carlo-based methods are sought for their superior accuracy.
The aim of this study is to compare dose distributions between the ACUROS algorithm and the GATE platform in various tissue densities and field sizes, focusing on smaller fields. This study was initiated with a homogeneous validation of the TrueBeam STX system, using measurements obtained from the Centre Hospitalier Interregional Edith Cavell (CHIREC) in Brussels...
March 22, 2024: Biomedical Physics & Engineering Express
https://read.qxmd.com/read/38517433/physical-dose-validation-of-dynamic-treatment-for-gamma-knife-radiosurgery
#35
JOURNAL ARTICLE
Benjamin Z Tham, Dionne M Aleman, Robert K Heaton, Håkan Nordström, Catherine Coolens
BACKGROUND: Dynamic treatment in Gamma Knife (GK) radiosurgery systems delivers radiation continuously with couch movement, as opposed to stationary step-and-shoot treatment where radiation is paused when moving between isocenters. Previous studies have shown the potential for dynamic GK treatment to give faster treatment times and improved dose conformity and homogeneity. However, these studies focused only on computational simulations and lack physical validation. PURPOSE: This study aims conduct dynamic treatment dosimetric validation with physical experimental measurements...
March 22, 2024: Medical Physics
https://read.qxmd.com/read/38517359/pet-spect-spectral-ct-cbct-imaging-in-a-small-animal-radiation-therapy-platform-a-monte-carlo-study-part-ii-biologically-guided-radiotherapy
#36
JOURNAL ARTICLE
Xiadong Li, Hui Wang, Lixia Xu, Yu Kuang
BACKGROUND: This study addresses the technical gap between clinical radiation therapy (RT) and preclinical small-animal RT, hindering the comprehensive validation of innovative clinical RT approaches in small-animal models of cancer and the translation of preclinical RT studies into clinical practices. PURPOSE: The main aim was to explore the feasibility of biologically guided RT implemented within a small-animal radiation therapy (SART) platform, with integrated quad-modal on-board positron emission tomography (PET), single-photon emission computed tomography, photon-counting spectral CT, and cone-beam CT (CBCT) imaging, in a Monte Carlo model as a proof-of-concept...
March 22, 2024: Medical Physics
https://read.qxmd.com/read/38516028/an-in-silico-planning-study-of-stereotactic-body-radiation-therapy-for-polymetastatic-patients-with-more-than-ten-extra-cranial-lesions
#37
JOURNAL ARTICLE
Federico Iori, Nathan Torelli, Jan Unkelbach, Stephanie Tanadini-Lang, Sebastian M Christ, Matthias Guckenberger
BACKGROUND AND PURPOSE: Limited data is available about the feasibility of stereotactic body radiation therapy (SBRT) for treating more than five extra-cranial metastases, and almost no data for treating more than ten. The aim of this study was to investigate the feasibility of SBRT in this polymetatstatic setting. MATERIALS AND METHODS: Consecutive metastatic melanoma patients with more than ten extra-cranial metastases and a maximum lesion diameter below 11 cm were selected from a single-center prospective registry for this in-silico planning study...
April 2024: Physics and Imaging in Radiation Oncology
https://read.qxmd.com/read/38515684/smartphone-based-thermography-in-flap-surgery-a-systematic-review-and-meta-analysis-of-perforator-identification
#38
JOURNAL ARTICLE
Loïc Van Dieren, Haïzam Oubari, Louise Callens, Yanis Berkane, Tom Quisenaerts, François Saget, Wiebren Tjalma, Gunther Steenackers, Curtis L Cetrulo, Alexandre G Lellouch, Filip Thiessen Ef
BACKGROUND: Thermography can be used in pre-operative planning of free perforator flap surgeries. Thermography assesses skin temperature by measuring the quantity of infrared radiation observed. In this meta-analysis, authors assess the sensitivity of smartphone-based thermal imaging (SBTI) in the detection of perforators and analyze the difference between static and dynamic imaging. MATERIALS AND METHODS: Authors followed the PRISMA guidelines for systematic reviews and meta-analyses...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38515394/peripheral-doses-beyond-electron-applicators-in-conventional-c-arm-linear-accelerators-a-systematic-literature-review
#39
REVIEW
Kapil Dev Maharaj, Joshua Dass, Mounir Ibrahim, Talat Mahmood, Pejman Rowshanfarzad
Background: This review investigates peripheral dose levels in electron beam treatments, comparing different manufacturers including Varian, Elekta, and Siemens. Accurate measurement of peripheral dose is vital for patient safety and precise radiation delivery in radiation therapy. Methods: This review followed PRISMA standards, conducting a comprehensive literature search from 1978 to July 2023. Emphasis was on identifying studies analyzing peripheral doses related to various electron beam energies, beam angle, field sizes, cutouts, and applicator combinations...
2024: Technology in Cancer Research & Treatment
https://read.qxmd.com/read/38514120/-a-new-preoperative-simulation-using-magnetic-resonance-imaging-bone-like-imaging-with-zero-echo-time-sequence
#40
JOURNAL ARTICLE
Akihiro Inoue, Yasuhiro Shiraishi, Taichi Furumochi, Takeharu Kunieda
This study aimed to evaluate the clinical usefulness of zero-echo time(ZTE)-based magnetic resonance imaging(MRI)in planning an optimal surgical approach and applying ZTE for anatomical guidance during transcranial surgery. P atients who underwent transcranial surgery and carotid endarterectomy and for whom ZTE-based MRI and magnetic resonance angiography(MRA)data were obtained, were analyzed by creating ZTE/MRA fusion images and 3D-ZTE-based MRI models. We examined whether these images and models could be substituted for computed tomography imaging during neurosurgical procedures...
March 2024: No Shinkei Geka. Neurological Surgery
keyword
keyword
20542
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.