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Tomisaku kawasaki 1967

Surjit Singh, Ankur Kumar Jindal
It has been 50 years since the legendary Japanese pediatrician, Dr Tomisaku Kawasaki, published his classic paper in 1967. Little was he to know at that time that this condition would not only be known after his name but would also become the commonest cause of acquired heart disease in children in most of the developed world. The etiology of this condition continues to remain an enigma, and the diagnosis is still based on a set of criteria that are entirely clinical. All pediatricians must be familiar with the various clinical presentations of this disease because delays in diagnosis and treatment can have disastrous consequences...
December 15, 2017: Indian Pediatrics
Tomisaku Kawasaki, Surjit Singh
No abstract text is available yet for this article.
January 2018: International Journal of Rheumatic Diseases
Yosikazu Nakamura
A half of century has passed since Dr. Tomisaku Kawasaki reported his 50 cases with Kawasaki disease (KD) in 1967. Since then, more than 300 000 cases have been reported to the nationwide epidemiologic surveys in Japan. However, the etiology and risk factors of the disease are still unknown. In this paper, the author emphasizes that the epidemiology of KD may indicate an infectious agent to be a potential trigger of disease in susceptible children.
January 2018: International Journal of Rheumatic Diseases
Ajit Bhagwat, Sachin Mukhedkar, Shriganesh Ekbote, John B Gordon
Kawasaki disease (KD) is an acute, self-limited vasculitis that occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric population in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment...
July 2015: Indian Heart Journal
Anil Kumar Singhi, Sreeja Pavithran, Kothandam Sivakumar
All giant Kawasaki aneurysms may not regress fully; some may eventually calcify, undergo thrombosis, and get detected in asymptomatic adults at later age. Tomisaku Kawasaki initially described this illness as mucocutaneous lymph node syndrome in childhood in 1967 and coronary arteritis was recognized later. We present a 58-year-old male, possibly one of the oldest surviving patients with giant coronary aneurysms who presented with large secundum atrial septal defect (ASD) with heart failure. This indicates that the disease was perhaps prevalent outside Japan even before the first Kawasaki's description...
May 2014: Annals of Pediatric Cardiology
Tomisaku Kawasaki, Shiro Naoe
We describe a short history of Kawasaki disease. In 1967, we published a paper entitled 'Infantile acute febrile mucocutaneous lymph node syndrome with specific desquamation of the fingers and toes. Clinical observation of 50 cases'; this was the first report on what is now called Kawasaki disease. Since then, many reports on cardiology, treatment, epidemiology, pathology and etiology of Kawasaki disease have been published. Furthermore, a recent Chapel Hill Consensus Statement on Kawasaki disease in the classification of vasculitis is given, along with a figure on the relationship and classification of childhood vasculitis by autopsy material...
April 2014: Clinical and Experimental Nephrology
Hung-Chi Lue, Lei-Ru Chen, Ming-Tai Lin, Luan-Yin Chang, Jou-Kou Wang, Chin-Yun Lee, Mei-Hwan Wu
BACKGROUND: Kawasaki disease (KD), first described by Dr. Tomisaku Kawasaki in 1967, was found for the first time in Taiwan in 1976. It continued to occur in increased numbers. For the study of incidence rates and epidemiological features of KD, we conducted five nationwide hospital surveys (NHS) in 1987, 1992, 1994, 2001 and 2008, respectively. We estimated also the annual incidence rates of KD during 1996-2007, based on the National Health Insurance (NHI) database, which had been implemented since 1995, covering 98% of the population in Taiwan...
April 2014: Pediatrics and Neonatology
Beverley Almeida, Pauline Gleeson, Kavita Chawla, Paul Brogan
Kawasaki disease was initially described by a Japanese paediatrician, Dr Tomisaku Kawasaki, in 1967. He reported an acute mucocutaneous lymph node syndrome affecting the skin, mucosa and lymph nodes. This initial description has since been expanded and is now recognized as Kawasaki disease, an acute systemic selflimiting vasculitis complicated by coronary arterial aneurysms, and even myocardial infarction in some patients (Shulman et al, 1995; Kato et al, 1996; Brogan et al, 2002).
February 2012: British Journal of Hospital Medicine
Shah Azmoon, David Atkinson, Matthew J Budoff
BACKGROUND: Kawasaki disease (KD) is an immune-mediated vasculitis of unknown etiology with self-limited clinical course that was first described in 1967 by Dr. Tomisaku Kawasaki. It is a disease of early childhood and rare past late adulthood but one that can have detrimental consequences when there is a delay in diagnosis and treatment. Cardiovascular complications causing increased morbidity and mortality may include coronary artery aneurysms, myocardial infarction, heart failure, arrhythmias, and peripheral artery occlusion...
May 2010: Congenital Heart Disease
John B Gordon, Andrew M Kahn, Jane C Burns
Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment...
November 17, 2009: Journal of the American College of Cardiology
Surjit Singh, Tomisaku Kawasaki
Kawasaki disease (KD) was first reported from Japan in 1967 by a young pediatrician, Tomisaku Kawasaki, while working at the Red Cross Hospital in Tokyo. Soon therafter, Marian Melish independently reported children with a similar clinical profile from Hawaii in the United States. KD has now been reported from all parts of the world, including several centers in India. Based on the epidemiology and clinical features, an infectious etiology has been suspected for long but no definitive causative agent has been implicated so far...
July 2009: Indian Pediatrics
W Raith, A Gamillscheg, B Heinzl, B H P Nagel, M Koestenberger, A Beitzke
BACKGROUND: Kawasaki syndrome was described for the first time by Tomisaku Kawasaki in 1967. This disease is characterized by panvasculitis of the small blood vessels of the skin, the mucous membranes, the internal organs and the coronary vessels and has an unclear etiology. Inflammatory changes in the coronary vessels or late diagnosis are prognostically unfavorable for the early and late mortality. AIM OF THE STUDY: Since two of our patients with Kawasaki syndrome with a short, severe course died despite receiving state-of-the-art treatment, we retrospectively evaluated the medical records of all the children we have treated since October 1978 with regard to the symptoms at the time of diagnosis, intervals between the onset of the disease, diagnosis, beginning of treatment and the result of treatment...
March 2009: Klinische P├Ądiatrie
Jun Abe
Kawasaki disease is an acute illness of early childhood primarily affecting coronary arteries accompanied by aneurysms. In his first report of 50 patients in Japanese in 1967, Dr. Tomisaku Kawasaki suggested interesting immunological abnormalities of Kawasaki disease, occasional appearances of autoantibodies and proliferations of reticuloendothelial cells in cervical lymph nodes. This review briefly summarizes the aberrations in the immune systems of patients with Kawasaki disease, in antibody production and in responses of macrophage and monocyte...
February 2008: Nihon Rinsho. Japanese Journal of Clinical Medicine
Tomisaku Kawasaki
Ten years after starting my pediatric career at the Japanese Red Cross Central Hospital (now Japanese Red Cross Medical Center) in Tokyo, I examined on January 5, 1961, a 4 year-3 month old boy, with curious clinical symptom-complex I had never experienced. This patient was a typical Kawasaki disease patient. But at that time I was unable to make a diagnosis. In February 1962, a case of suspected sepsis was referred to me from a neighboring doctor. After admitting the child into the hospital, the patient had a similar clinical course as the previous patient...
February 2008: Nihon Rinsho. Japanese Journal of Clinical Medicine
Amir H Ashrafi, Jenny Wang, Christina A Stockwell, David Lloyd, James B McAlvin, Pierre Russo, Bahig M Shehata
Kawasaki disease (KD) is a systemic vasculitis condition with a relatively unknown etiology. First described in 1967 by Tomisaku Kawasaki in Japan, KD has come to be widely diagnosed in every region of the world. The disease has a high prevalence in children ages 6 months to 5 years, particularly in those of Japanese descent. Patients often present with a high fever, rash, lymphadenopathy, and conjunctival injections, but there is no diagnostic test for KD. This paper presents data from our Kawasaki registry including 99 patients with emphasis on Kawasaki cardiopathy...
November 2007: Pediatric and Developmental Pathology
Jane C Burns
No abstract text is available yet for this article.
November 2002: Pediatric Infectious Disease Journal
Noriko Shibuya, Kazuhiko Shibuya, Hitoshi Kato, Masayoshi Yanagisawa
OBJECTIVE: Kawasaki disease (KD) was first reported by Tomisaku Kawasaki in 1967 in Japan. Large-scale nationwide epidemiologic surveys have been conducted continuously by the Japan Kawasaki Disease Research Committee; however, there were very few reports of KD before 1967. This study was performed to clarify when KD appeared in Japan. DESIGN: We investigated the medical charts of patients who had been hospitalized at Tokyo University Hospital between 1940 and 1965...
August 2002: Pediatrics
A J Lloyd, C Walker, M Wilkinso
Kawasaki disease (KD) is an acute systemic febrile illness of unknown aetiology, predominantly affecting children under five years of age. Initially described in 1967 by Tomisaku Kawasaki, it is now the most common cause of acquired heart disease in children in the developed world. Although normally self-limiting, KD is associated with a range of complications, the most important of which is the development of life-threatening coronary artery abnormalities. Here, we examine the evidence supporting the concept that KD is caused by an infectious agent...
2001: British Journal of Biomedical Science
J C Burns, H I Kushner, J F Bastian, H Shike, C Shimizu, T Matsubara, C L Turner
Tomisaku Kawasaki published the first English-language report of 50 patients with Kawasaki disease (KD) in 1974. Since that time, KD has become the leading cause of acquired heart disease among children in North America and Japan. Although an infectious agent is suspected, the cause remains unknown. However, significant progress has been made toward understanding the natural history of the disease and therapeutic interventions have been developed that halt the immune-mediated destruction of the arterial wall...
August 2000: Pediatrics
J Samuel, J O'Sullivan
Kawasaki disease is an acute vasculitis of small- and medium-sized blood vessels which was first described by Dr Tomisaku Kawasaki in 1967. Involvement of the coronary arteries is common and may be life threatening or cause long-term cardiovascular complications.
January 17, 1996: British Journal of Hospital Medicine
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