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https://www.readbyqxmd.com/read/28092279/association-between-long-term-blood-pressure-control-and-ten-year-progression-in-carotid-arterial-stiffness-among-hypertensive-individuals-the-multiethnic-study-of-atherosclerosis
#1
Yacob G Tedla, Adam D Gepner, Dhananjay Vaidya, Laura Colangelo, James H Stein, Kiang Liu, Philip Greenland
BACKGROUND: Arterial stiffness was shown to be higher among hypertensive patients with diabetes than those without diabetes and among older than younger hypertensive patients. We examined whether the association between long-term blood pressure (BP) control and 10-year progression in carotid arterial stiffness varies by diabetes status and age. METHODS: Participants were 906 individuals with hypertension at baseline and three follow-up visits in the Multi-Ethnic Study of Atherosclerosis (mean age 63...
January 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28091441/process-and-outcome-measures-of-quality-of-care-at-the-diabetes-outpatient-clinic-university-college-hospital-ibadan
#2
J O Adeleye, M A Kuti
OBJECTIVE: The study aims to assess the quality of care provided at a diabetes outpatient clinic of a tertiary hospital in Nigeria using quality indicators approved by the National Diabetes Quality Improvement Alliance (NDQIA). MATERIALS AND METHODS: The medical records of patients who had visited the clinic at least two times within a 12 months period preceding the index visit were reviewed during a 5 month period. Process measure indicators, approved by the NDQIA (evaluating the functioning of the clinic) and outcome measures, published by the American Diabetes Association, (evaluating the health status of the attending patients) were retrieved from the medical records...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28090680/validity-of-noninvasive-composite-scores-to-assess-cardiovascular-risk-in-10-year-old-children
#3
Ø Lerum, E Aadland, L B Andersen, S A Anderssen, G K Resaland
Agreement between and classification accuracy of six different noninvasive composite scores and a cardiovascular disease (CVD) risk factor score were investigated in 911 (466 boys and 445 girls) 10-year-old Norwegian children. A CVD risk factor score (triglyceride, total cholesterol/HDL ratio, homeostasis model assessment of insulin resistance, systolic blood pressure (SBP), waist-to-height ratio (WHtR), and cardiorespiratory fitness) and six noninvasive risk scores (fitness+three different measurements of fatness (body mass index (BMI), WHtR, and skinfolds), with and without inclusion of SBP) were calculated (mean z-score by gender)...
January 16, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28090231/effects-of-ipragliflozin-on-diabetic-nephropathy-and-blood-pressure-in-patients-with-type-2-diabetes-an-open-label-study
#4
Daisuke Ito, Emi Ikuma-Suwa, Kazuyuki Inoue, Kimie Kaneko, Morifumi Yanagisawa, Kouichi Inukai, Mitsuhiko Noda, Akira Shimada
BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are novel agents used to treat type 2 diabetic patients. We investigated the efficacy of the SGLT2 inhibitor ipragliflozin on diabetic nephropathy in Japanese patients with type 2 diabetes. METHODS: A 50 mg dose of ipragliflozin was administered for 24 weeks to 50 patients with type 2 diabetes who were concomitantly managed with diet and exercise therapy alone or antidiabetic medications other than SGLT2 inhibitors...
February 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28090225/efficacy-and-safety-of-combination-therapy-consisting-of-angiotensin-ii-type-1-receptor-blocker-calcium-channel-blocker-and-hydrochlorothiazide-in-patients-with-hypertension
#5
Yuhei Shiga, Shin-Ichiro Miura, Kota Motozato, Yuka Yoshimine, Kenji Norimatsu, Tadaaki Arimura, Rie Koyoshi, Joji Morii, Takashi Kuwano, Ken Inoue, Tetsuro Shirotani, Kazuaki Fujisawa, Eiyu Matsunaga, Keijiro Saku
BACKGROUND: Many patients continue to have high blood pressure (BP) even after treatment with high-dose (H)-angiotensin II type 1 receptor blocker (ARB)/calcium channel blocker (CCB) or middle-dose (M)-ARB/CCB/hydrochlorothiazide (HCTZ). METHODS: Thirty-two hypertensive patients who had the use of H-ARB/CCB or M-ARB/CCB/HCTZ were enrolled in this study. We applied a changeover with a switch to H-ARB (telmisartan 80 mg/day)/CCB (amlodipine 5 mg/day or nifedipine CR 40 mg/day)/HCTZ (12...
February 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28089459/effect-of-renal-denervation-on-kidney-function-in-patients-with-chronic-kidney-disease
#6
Dagmara Hering, Petra Marusic, Jacqueline Duval, Yusuke Sata, Geoffrey A Head, Kate M Denton, Sally Burrows, Antony S Walton, Murray D Esler, Markus P Schlaich
AIMS: Renal denervation (RDN) can reduce blood pressure (BP) and slow the decline of renal function in chronic kidney disease (CKD) up to one year. Whether this effect is maintained beyond 12months and whether the magnitude of BP reduction affects estimated glomerular filtration rate (eGFR) is unknown. METHODS AND RESULTS: We examined eGFR in 46 CKD patients (baseline eGFR ≤60mL/min/1.73m(2)) on a yearly basis from 60months before to 3, 6, 12 and 24months after RDN...
January 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28089457/a-meta-analysis-of-add-on-use-of-spironolactone-in-patients-with-resistant-hypertension
#7
Di Zhao, Hui Liu, Pingshuan Dong, Jingdong Zhao
OBJECTIVE: The efficacy of add-on use of spironolactone in patients with resistant hypertension has been investigated in several small studies. We performed this meta-analysis evaluating the efficacy of add-on use of spironolactone in these patients. METHODS: We searched Pubmed, Web of Science, and Cochrane Central for all published studies evaluating add-on use of spironolactone in patients with resistant hypertension. Only randomized controlled trials determining antihypertensive effects of spironolactone were considered...
December 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28089168/the-relationship-between-dietary-intake-and-other-cardiovascular-risk-factors-with-blood-pressure-in-individuals-without-a-history-of-a-cardiovascular-event-evidence-based-study-with-5670-subjects
#8
Mohsen Mazidi, Mohsen Nematy, Ali Reza Heidari-Bakavoli, Zahra Namadchian, Majid Ghayour-Mobarhan, Gordon A Ferns
BACKGROUND AND AIM: Raised blood pressure is a leading cause of morbidity and mortality worldwide; improved nutritional approaches to population-wide prevention are required.We aimed to investigate the relationship between dietary intake and other cardiovascular risk factors with blood pressure in individuals without a history of a cardiovascular event in an Iranian cohort. MATERIAL AND METHOD: A cross-sectional study of 5670 healthy subjects [approximately 40% (n=2179) males and 60% (n=3491) females] was undertaken in a sample from northeastern Iran...
December 9, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28088531/the-effect-of-dissolved-organic-matter-on-soybean-peroxidase-mediated-removal-of-triclosan-in-water
#9
Jianhua Li, Ya Zhang, Jianbiao Peng, Xinan Wu, Shixiang Gao, Liang Mao
Dissolved organic matter (DOM) is ubiquitous in water and involved in numerous important chemical processes in aqueous systems, enabling it a unique challenge for a variety of water treatment processes. Soybean peroxidase (SBP)-based enzymatic process, as a promising treatment technique, has been successfully applied to remove pollutants in wastewaters such as coal-tar and refinery wastewater. In this study, the effect of DOM on the removal of polychlorinated aromatic antimicrobials triclosan (TCS) by SBP was investigated...
January 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28086813/information-exchange-networks-of-health-care-providers-and-evidence-based-cardiovascular-risk-management-an-observational-study
#10
Naomi Heijmans, Jan van Lieshout, Michel Wensing
BACKGROUND: Although a wide range of preventive and clinical interventions has targeted cardiovascular risk management (CVRM), outcomes remain suboptimal. Therefore, the question is what additional determinants of CVRM and outcomes can be identified and addressed to optimize CVRM. In this study, we aimed to identify new perspectives for improving healthcare delivery and explored associations between information exchange networks of health care providers and evidence-based CVRM. METHODS: This observational study was performed parallel to a randomized clinical trial which aimed to improve professional performance of practice nurses in the Netherlands...
January 13, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28081487/comparative-genome-wide-phylogenetic-and-expression-analysis-of-sbp-genes-from-potato-solanum-tuberosum
#11
Musa Kavas, Aslıhan Kurt Kızıldoğan, Büşra Abanoz
Flowering time is a very important phase in transition to reproductive stage of life in higher plants. SQUAMOSA promoter-binding protein (SBP) gene family encodes plant-specific transcription factors that are involved in regulation of several developmental processes, especially flowering. Although SBP-box genes have been identified in different plants, there have been no study indicating the regulatory effect of SBP box in potato flowering. Here, we report for the first time the identification and characterization of SBP-box transcription factors as well as determination of expression level of SBP-box genes in Solanum tuberosum L...
January 4, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28081369/randomized-controlled-ethanol-cookstove-intervention-and-blood-pressure-in-pregnant-nigerian-women
#12
Donee Alexander, Amanda Northcross, Nathaniel Wilson, Anindita Dutta, Rishi Pandya, Tope Ibigbami, Damilola Adu, John Olamijulo, Oludare Morhason-Bello, Theodore Karrison, Oladosu Ojengbede, Christopher O Olopade
RATIONALE: Hypertension during pregnancy is a leading cause of maternal mortality. Exposure to household air pollution (HAP) elevates blood pressure (BP). OBJECTIVES: Investigate ability of clean cookstove intervention to lower BP during pregnancy. METHODS: A randomized, controlled trial (RCT) was conducted in Nigeria. Pregnant women cooking with kerosene or firewood were randomly assigned to ethanol (n = 162) or control arms (n = 162). BP measurements were taken during 6 antenatal visits...
January 12, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28081200/fitter-women-did-not-have-attenuated-hemodynamic-responses-to-psychological-stress-compared-with-age-matched-women-with-lower-levels-of-fitness
#13
Sisitha U Jayasinghe, Susan J Torres, Mais Hussein, Steve F Fraser, Gavin W Lambert, Anne I Turner
According to the 'cross stressor adaptation hypothesis', regular exercise acts as a buffer against the detrimental effects of stress. Nevertheless, evidence that higher levels of cardiorespiratory fitness moderate hemodynamic responses to acute psychological stress is inconclusive, especially in women. Women aged 30-50 years (in the mid-follicular phase of the menstrual cycle) with higher (n = 17) and lower (n = 17) levels of fitness were subjected to a Trier Social Stress Test (TSST). Continuous, non-invasive measurements were made of beat-to-beat, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), cardiac output (CO), left ventricular ejection time (LVET), maximum slope, pulse interval (PI) and total peripheral resistance (TPR)...
2017: PloS One
https://www.readbyqxmd.com/read/28079826/waist-to-height-ratio-is-the-best-anthropometric-predictor-of-hypertension-a-population-based-study-with-women-from-a-state-of-northeast-of-brazil
#14
Tainá C S Caminha, Haroldo S Ferreira, Narithania S Costa, Ricardo P Nakano, Renata Elyonara S Carvalho, Antônio F S Xavier, Monica L Assunção
The WHO recommends the use of some anthropometric parameters as a screening resource for individuals under cardiometabolic risk. However, in the validation of these indicators, Brazilian women were not included. These women have different anthropometric profile compared to women who integrated the samples of the validation studies. We aimed to verify the accuracy of anthropometric indicators as a resource for the screening of women with hypertension. A cross-sectional study, with a probability sample of 3143 women (20-49 years) from the state of Alagoas (northeast of Brazil), was carried out...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28077859/benefits-of-whole-body-vibration-training-on-arterial-function-and-muscle-strength-in-young-overweight-obese-women
#15
Stacey Alvarez-Alvarado, Salvador J Jaime, Michael J Ormsbee, Jeremiah C Campbell, Joy Post, Jacob Pacilio, Arturo Figueroa
The early arterial dysfunction linked with obesity and a sedentary lifestyle heightens the likelihood of suffering from future cardiovascular events. Whole-body vibration training (WBVT) may improve systemic arterial stiffness (brachial-ankle pulse wave velocity (baPWV)) and muscle strength in pre- and post-menopausal women. However, the effectiveness of WBVT to impact the arterial segments included in baPWV is unknown. The aim of this study was to investigate the effects of WBVT on aortic and leg arterial stiffness in young sedentary overweight/obese women...
January 12, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28077420/polymorphisms-of-leptin-g2548a-and-leptin-receptor-q223r-and-k109r-genes-and-blood-pressure-during-pregnancy-and-the-postpartum-period-a-cohort
#16
Dayana R Farias, Ana B Franco-Sena, Fernanda Rebelo, Gil F Salles, Cláudio J Struchiner, Maisa C Martins, Gilberto Kac
BACKGROUND: The genetic component related to blood pressure (BP) changes during pregnancy is still not elucidated. Thus, the aim of the study was to evaluate the association between leptin and leptin receptor polymorphisms and systolic (SBP) and diastolic BP (DBP) variation during pregnancy and the postpartum period. METHODS: Prospective cohort of 146 women followed at a Public Health Center in Rio de Janeiro, Brazil, during pregnancy and the postpartum. SBP and DBP (mm Hg) were measured using an automatic sphygmomanometer...
February 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28076802/peldor-spectroscopy-reveals-two-defined-states-of-a-sialic-acid-trap-transporter-sbp-in-solution
#17
Janin Glaenzer, Martin F Peter, Gavin H Thomas, Gregor Hagelueken
The tripartite ATP-independent periplasmic (TRAP) transporters are a widespread class of membrane transporters in bacteria and archaea. Typical substrates for TRAP transporters are organic acids including the sialic acid N-acetylneuraminic acid. The substrate binding proteins (SBP) of TRAP transporters are the best studied component and are responsible for initial high-affinity substrate binding. To better understand the dynamics of the ligand binding process, pulsed electron-electron double resonance (PELDOR, also known as DEER) spectroscopy was applied to study the conformational changes in the N-acetylneuraminic acid-specific SBP VcSiaP...
January 10, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28076452/angiotensin-1-7-relieved-renal-injury-induced-by-chronic-intermittent-hypoxia-in-rats-by-reducing-inflammation-oxidative-stress-and-fibrosis
#18
W Lu, J Kang, K Hu, S Tang, X Zhou, S Yu, L Xu
We aimed to study the renal injury and hypertension induced by chronic intermittent hypoxia (CIH) and the protective effects mediated by angiotensin 1-7 [Ang(1-7)]. We randomly assigned 32 male Sprague-Dawley rats (body weight 180-200 g) to normoxia control, CIH, Ang(1-7)-treated normoxia, and Ang(1-7)-treated CIH groups. Systolic blood pressure (SBP) was monitored at the start and end of each week. Renal sympathetic nerve activity (RSNA) was recorded. CTGF and TGF-β were detected by immunohistochemistry and western blotting...
January 9, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28074870/microrna-155-is-upregulated-in-ascites-in-patients-with-spontaneous-bacterial-peritonitis
#19
Philipp Lutz, Mohamed M Haimid, Alessandra Pohlmann, Jennifer Lehmann, Christian Jansen, Robert Schierwagen, Sabine Klein, Christian P Strassburg, Ulrich Spengler, Jonel Trebicka
MircoRNA's (miR) have been recognised as important modulators of gene expression and potential biomarkers. However, they have been rarely investigated in bio fluids apart from blood. We investigated the association of miR-125b and miR-155 with complications of cirrhosis. Ascites was prospectively collected from patients with cirrhosis undergoing paracentesis at our department. miR's were determined in the supernatant using qPCR and normalized by SV-40. Clinical parameters were assessed at paracentesis and during follow-up...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28066111/clinical-effectiveness-and-safety-of-low-cost-versus-innovator-brand-amlodipine-in-hypertension-a-single-blinded-randomized-crossover-noninferiority-trial
#20
Alak Kumar Das, Suparna Chatterjee, Jyotirmoy Pal
OBJECTIVES: A single-blinded, randomized, crossover, noninferiority trial was conducted to evaluate clinical effectiveness and safety of low-cost brand (LCB) versus innovator brand (IB) amlodipine in essential hypertension. MATERIALS AND METHODS: The primary end-point was change of systolic blood pressure (BP) from baseline to study end. Adult patients with Stage 1 hypertension or isolated systolic hypertension were randomized to receive 5 mg amlodipine LCB or IB once daily for 6 weeks in each period in a 2 × 2 crossover manner with three follow-up visits in each sequence...
November 2016: Indian Journal of Pharmacology
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