keyword
https://read.qxmd.com/read/38537025/effects-of-an-early-intensive-blood-pressure-lowering-strategy-using-remifentanil-and-dexmedetomidine-in-patients-with-spontaneous-intracerebral-hemorrhage-a-multicenter-prospective-superiority-randomized-controlled-trial
#1
JOURNAL ARTICLE
Rui Dong, Fen Li, Bin Li, Qiming Chen, Xianjian Huang, Jiehua Zhang, Qibing Huang, Zeli Zhang, Yunxing Cao, Mingbiao Yang, Jianwei Li, Zhanfu Li, Cuiyu Li, Guohua Liu, Shu Zhong, Guang Feng, Ming Zhang, Yumei Xiao, Kangyue Lin, Yunlong Shen, Huanzhang Shao, Yuan Shi, Xiangyou Yu, Xiaopeng Li, Lan Yao, Xinyu Du, Ying Xu, Pei Kang, Guoyi Gao, Bin Ouyang, Wenjin Chen, Zhenhua Zeng, Pingyan Chen, Chunbo Chen, Hong Yang
BACKGROUND: Although it has been established that elevated blood pressure and its variability worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during the acute phase still lacks robust evidence. A blood pressure-lowering regimen using remifentanil and dexmedetomidine might be a reasonable therapeutic option given their analgesic and anti-sympathetic effects. The objective of this superiority trial was to validate the efficacy and safety of this blood pressure-lowering strategy that uses remifentanil and dexmedetomidine in patients with acute intracerebral hemorrhage...
March 27, 2024: Anesthesiology
https://read.qxmd.com/read/38536806/lower-autonomic-arousal-as-a-risk-factor-for-criminal-offending-and-unintentional-injuries-among-female-conscripts
#2
JOURNAL ARTICLE
Sofi Oskarsson, Anneli Andersson, Bridget M Bertoldi, Antti Latvala, Ralf Kuja-Halkola, Brittany Evans, Adrian Raine, Christopher J Patrick, Henrik Larsson, Catherine Tuvblad
BACKGROUND: Lower autonomic arousal is a well-known correlate of criminal offending and other risk-taking behaviors in men, but few studies have investigated this association in women. AIM: To test associations between autonomic arousal and criminal offending as well as unintentional injuries among female conscripts. METHODS: All women born 1958-1994 in Sweden who participated in voluntary military conscription (n = 12,499) were identified by linking Swedish population-based registers...
2024: PloS One
https://read.qxmd.com/read/38535590/genetic-characterization-of-the-rap-1a-and-sbp-4-genes-of-babesia-species-infecting-cattle-from-selangor-malaysia-and-ribah-nigeria
#3
JOURNAL ARTICLE
Adamu Isah Gano, Siti Zubaidah Ramanoon, Nor-Azlina Abdul Aziz, Mazlina Mazlan, Mohd Rosly Shaari, Abdullahi Aliyu, Muhammad Bashir Bello, Mustapha Umar Imam, Hazilawati Hamzah
Bovine babesiosis has substantial economic implications in the cattle industry, emphasizing the need for a thorough understanding of the genetic diversity of the causative apicomplexan pathogen. Although babesiosis has been extensively studied globally, the genetic diversity of Babesia species in Malaysian and Nigerian cattle remains unreported. This study aims to bridge this gap by detecting and characterizing Babesia species in selected cattle herds. Our investigation explores the genetic diversity of Babesia species in cattle from Selangor, Malaysia, and Ribah, Nigeria...
March 13, 2024: Pathogens
https://read.qxmd.com/read/38534970/sars-cov-2-infection-is-an-independent-risk-factor-for-decompensation-in-cirrhosis-patients
#4
JOURNAL ARTICLE
Mark Ayoub, Julton Tomanguillo, Carol Faris, Nadeem Anwar, Harleen Chela, Ebubekir Daglilar
BACKGROUND: SARS-CoV-2 causes varied gastrointestinal symptoms. Cirrhosis patients face higher mortality rates from it, especially those with decompensated cirrhosis. This study examines SARS-CoV-2's impact on decompensation in previously compensated cirrhotic patients. METHODS: We analyzed the Global Collaborative Network, comprising 98 healthcare organizations across sixteen countries, using TriNetX's deidentified research database. Compensated cirrhosis patients were split into two groups: one with SARS-CoV-2-positive patients and another testing negative...
February 25, 2024: Diseases (Basel)
https://read.qxmd.com/read/38533289/screening-of-individuals-with-type-2-diabetes-on-anti-diabetic-agents-for-probable-hypoglycaemia-using-the-stanford-hypoglycemia-questionnaire-shq-in-outpatient-settings-a-cross-sectional-study-from-outpatient-diabetes-care-centres-in-north-india
#5
JOURNAL ARTICLE
Rajiv Awasthi, Arun K Pande, Kumar P Chandra, Vivek Agarwal, Mukulesh Gupta, Ajoy Tewari, Nitin Gupta, Santosh Chaubey, Sandeep Chaudhary, Sajid Ansari, Dinesh Kumar
INTRODUCTION: The study was aimed at identifying the incidence of unreported probable hypoglycaemia in individuals with type 2 diabetes (T2DM) on anti-diabetic medications, using the screening Stanford Hypoglycemia Questionnaire (SHQ) in real-world situations. METHODS: It was a multicentre cross-sectional study on consecutive individuals attending 10 diabetes care centres in Lucknow, Uttar Pradesh, India. The inclusion criteria were as follows: known individuals with T2DM, literate, age greater than or equal to 18 years, on at least one anti-diabetic agent for more than a month and not engaged in regular self-monitoring of blood glucose (SMBG)...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38533245/correlation-between-tibial-and-femoral-bone-and-cartilage-changes-in-end-stage-knee-osteoarthritis
#6
JOURNAL ARTICLE
Fahimeh Azari, William Colyn, Johan Bellemans, Lennart Scheys, G H van Lenthe
Knee osteoarthritis is a whole joint disease highlighting the coupling of cartilage and bone adaptations. However, the structural properties of the subchondral bone plate (SBP) and underlying subchondral trabecular bone (STB) in the femoral compartment have received less attention compared to the tibial side. Furthermore, how the properties in the femoral compartment relate to those in the corresponding tibial site is unknown. Therefore, this study aimed to quantify the structural bone and cartilage morphology in the femoral compartment and investigate its association with those of the tibial plateau...
April 2024: JBMR Plus
https://read.qxmd.com/read/38533045/a-continuous-cuffless-blood-pressure-measurement-from-optimal-ppg-characteristic-features-using-machine-learning-algorithms
#7
JOURNAL ARTICLE
Araf Nishan, S M Taslim Uddin Raju, Md Imran Hossain, Safin Ahmed Dipto, S M Tanvir Uddin, Asif Sijan, Md Abu Shahid Chowdhury, Ashfaq Ahmad, Md Mahamudul Hasan Khan
BACKGROUND AND OBJECTIVE: Hypertension is a potentially dangerous health condition that can be detected by measuring blood pressure (BP). Blood pressure monitoring and measurement are essential for preventing and treating cardiovascular diseases. Cuff-based devices, on the other hand, are uncomfortable and prevent continuous BP measurement. METHODS: In this study, a new non-invasive and cuff-less method for estimating Systolic Blood Pressure (SBP), Mean Arterial Pressure (MAP), and Diastolic Blood Pressure (DBP) has been proposed using characteristic features of photoplethysmogram (PPG) signals and nonlinear regression algorithms...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38533001/waist-to-height-ratio-is-a-better-predictor-of-hypertension-in-women-during-recovery-from-anesthesia-compared-to-bmi-waist-to-hip-ratio-and-waist-circumference
#8
JOURNAL ARTICLE
Qinqin Cao, Chengjuan Fan, Yufen Fei, Shouxin Zhang, Tong Shen, Haihong Meng
This was an observational study of patients with benign breast tumors intended to investigate and compare the predictive value of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) for hypertension in the recovery room. Logistic regression analysis was used to determine the association between these body fat anthropometric indices and hypertension. Receiver operating characteristic curve (ROC) analysis was performed to assess the comparative predictive ability...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38532571/biosignatures-of-defective-sebaceous-gland-activity-in-sebum-rich-and-sebum-poor-skin-areas-in-adult-atopic-dermatitis
#9
JOURNAL ARTICLE
Alessia Cavallo, Emanuela Camera, Grazia Bottillo, Miriam Maiellaro, Mauro Truglio, Federico Marini, Marlène Chavagnac-Bonneville, Aurélie Fauger, Eric Perrier, Flavia Pigliacelli, Mauro Picardo, Antonio Cristaudo, Maria Mariano
Atopic dermatitis (AD) is a composite disease presenting disruption of the skin permeability barrier (SPB) in the stratum corneum (SC). Recent evidence supports derangement of the sebaceous gland (SG) activity in the AD pathomechanisms. The objective of this study was to delineate profiles of both sebaceous and epidermal lipids and of aminoacids from SG-rich (SGR) and SG-poor (SGP) areas in AD. Both sebum and SC were sampled from SGR areas, while SC was sampled also from SGP areas in 54 adult patients with AD, consisting of 34 and 20 subjects, respectively with and without clinical involvement of face, and in 44 age and sex-matched controls...
March 2024: Experimental Dermatology
https://read.qxmd.com/read/38532356/the-impact-of-communication-training-on-the-clinical-care-of-hypertension-in-general-practice-a-cluster-randomized-controlled-trial-in-china
#10
JOURNAL ARTICLE
Chuan Zou, Lili Deng, Jianzhao Luo, Hua Dai, Yu Zhang, Ru Guo, Xiaolu Luo, Rong Yang, Haiqi Song, John Spicer, Qian Zhao, Xiaoyang Liao
BACKGROUND: Hypertension is one of the most common chronic diseases with a low control rate globally. The effect of communication skills training contributing to hypertension control remains uncertain. The aim of the present study was to assess the effectiveness of an educational intervention based on the Calgary-Cambridge guide in improving hypertensive management. METHODS: A cluster randomized controlled trial enrolled 27 general practitioners (GPs) and 540 uncontrolled hypertensive patients attending 6 community health centers in Chengdu, China...
March 26, 2024: BMC Prim Care
https://read.qxmd.com/read/38531251/machine-learning-based-predictive-model-for-abdominal-diseases-using-physical-examination-datasets
#11
JOURNAL ARTICLE
Wei Chen, YuJie Zhang, Weili Wu, Hui Yang, Wenxiu Huang
Abdominal ultrasound is a key non-invasive imaging method for diagnosing liver, kidney, and gallbladder diseases, despite its clinical significance, not all individuals can undergo abdominal ultrasonography during routine health check-ups due to limitations in equipment, cost, and time. This study aims to use basic physical examination data to predict the risk of diseases of the liver, kidney, and gallbladder that can be diagnosed via abdominal ultrasound. Basic physical examination data contain gender, age, height, weight, BMI, pulse, systolic blood pressure (SBP), diastolic blood pressure (DBP), high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol, triglycerides, fasting blood glucose (FBG), and uric acid-we established seven single-label predictive models and one multi-label predictive model...
March 11, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38530689/efficacy-of-sacubitril-valsartan-on-survival-and-cardiac-remodeling-in-hypotensive-heart-failure-with-reduced-ejection-fraction-a-multicenter-study
#12
JOURNAL ARTICLE
Chien-Yi Hsu, Fa-Po Chung, Chieh-Ju Chao, Ying-Ju Chen, Cho-Kai Wu, Yen-Wen Wu, Jin-Long Huang, Pao-Hsien Chu, Charles Jia-Yin Hou, Hung-Yu Chang, Chung-Lieh Hung
OBJECTIVE: To investigate whether hypotensive patients diagnosed with heart failure and reduced ejection fraction (HFrEF) might benefit from angiotensin receptor-neprilysin inhibitors (ARNis) in real-world practice because patients with baseline systolic blood pressure (SBP) of less than 100 mm Hg have been excluded from landmark trials. PATIENTS AND METHODS: In this multicenter study conducted between January 1, 2013, and December 31, 2021, a total of 7562 symptomatic patients with HFrEF were enrolled and grouped by SBP (hypotension was defined as an SBP of less than 100 mm Hg) and ARNi use as follows: group 1, hypotensive/non-ARNi users (n=484); group 2, hypotensive/ARNi users (n=308); group 3, nonhypotensive/non-ARNi users (n=4560); and group 4, nonhypotensive/ARNi users (n=2210)...
March 26, 2024: Mayo Clinic Proceedings
https://read.qxmd.com/read/38530512/expression-of-long-non-coding-rna-gas5-by-first-trimester-screening-predicts-the-occurrence-of-gestational-hypertension-and-pre-eclampsia
#13
JOURNAL ARTICLE
Li Wang, Jinfeng Chen, Huihui Li, Qianqian Zhou, Chunxia Zhang
AIMS: Hypertensive disorders of pregnancy (HDP) is a unique disease during gestational period, which is detrimental to pregnancy outcome. This study examined the clinical significance of long non-coding RNA GAS5 in gestational hypertension (GH) and preeclampsia (PE), aiming to explore potential biomarkers for the disease detection. METHODS: 180 pregnant women with HPD including 90 cases with GH and 90 cases with PE, and another 100 healthy pregnant women were enrolled...
March 26, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38530295/photobiomodulation-for-blood-pressure-and-heart-rate-reduction-in-mastectomized-women-on-hormone-blockers-a-randomized-controlled-trial
#14
JOURNAL ARTICLE
Juliano Abreu Pacheco, Kelly Fernanda Molena, Eugenia Velludo Veiga
Objective: To assess the impact of intravascular laser irradiation of blood (ILIB) on the primitive carotid artery (PCA) hemodynamic variables, specifically blood pressure (BP) and heart rate (HR), in mastectomized patients undergoing hormone blocker treatments. Materials and methods: This study is a controlled, experimental, and randomized clinical trial. Patients were allocated into two groups: the experimental group (G1)-patients who received ILIB therapy using a 660 nm laser targeted at the PCA, and the control group (G2)-patients who did not receive ILIB therapy...
March 26, 2024: Photobiomodulation, photomedicine, and laser surgery
https://read.qxmd.com/read/38529482/high-intensity-interval-training-improves-respiratory-and-cardiovascular-adjustments-before-and-after-initiation-of-exercise
#15
JOURNAL ARTICLE
Go Ito, Marina Feeley, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Hidehiro Nakahara, Tadayoshi Miyamoto
Purpose: High-intensity interval training (HIIT) may induce training-specific physiological adaptations such as improved respiratory and cardiovascular adjustments before and after the onset of high-intensity exercise, leading to improved exercise performance during high-intensity exercise. The present study investigated the effects of HIIT on time-dependent cardiorespiratory adjustment during maximal exercise and before and after initiation of high-intensity exercise, as well as on maximal exercise performance...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38528480/early-ambulation-protocol-after-diagnostic-transfemoral-cerebral-angiography-an-evidence-based-practice-project
#16
JOURNAL ARTICLE
Hao Liang, Richun Ye, Nana Song, Canhui Zhu, Miaolong Xu, Qiaoyu Ye, Lin Wei, Jiehan Chen
BACKGROUND: No uniform consensus has been achieved regarding the ambulation protocol after transfemoral cerebral angiography (TFA). Until now, in most hospitals patients are prescribed 8-12 h strict immobilization along with bed rest in the supine position after TFA in China, which causes great discomfort to patients. OBJECTIVE: To evaluate the effect of an evidence-based early ambulation protocol on the prevention of vascular complications and general discomfort in patients following transfemoral cerebral angiography (TFA)...
March 25, 2024: BMC Neurology
https://read.qxmd.com/read/38525868/associations-of-traditional-cardiovascular-risk-factors-with-15-year-blood-pressure-change-and-trajectories-in-chinese-adults-a-prospective-cohort-study
#17
JOURNAL ARTICLE
Yiqian Zhang, Qiufen Sun, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Huaidong Du, Ling Yang, Yiping Chen, Xiaoming Yang, Xiaofang Chen, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
OBJECTIVE: How traditional cardiovascular disease (CVD) risk factors are related to long-term blood pressure change (BPC) or trajectories remain unclear. We aimed to examine the independent associations of these factors with 15-year BPC and trajectories in Chinese adults. METHODS: We included 15 985 participants who had attended three surveys, including 2004-2008 baseline survey, and 2013-2014 and 2020-2021 resurveys, over 15 years in the China Kadoorie Biobank (CKB)...
March 14, 2024: Journal of Hypertension
https://read.qxmd.com/read/38525393/comparative-evaluation-of-direct-laryngoscopy-versus-glidescope-for-the-purpose-of-laryngoscopy-management-and-intubation-in-candidates-of-cesarean-delivery-with-general-anesthesia
#18
JOURNAL ARTICLE
Azim Honarmand, Mahtab Ebrahim Babaei, Mohammad Jafari, Mohammad Reza Safavi
BACKGROUND: The present study aimed at comparing the hemodynamic responses to laryngoscopy and initiation of intubation with either direct or video-assisted laryngoscopy. MATERIALS AND METHODS: This double-blind clinical trial was performed on 90 pregnant women candidates for cesarean section under general anesthesia. The participants were divided into two groups. In the first group, intubation was performed using direct Macintosh laryngoscope (MCL group). The second group underwent intubation using the GlideScope video laryngoscope (GSL group)...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525193/effects-of-continuous-supplementation-of-acanthopanax-senticosus-harms-on-the-cardiac-autonomic-function-of-community-dwelling-elderly-individuals-during-resting-and-standing-tests-a-randomized-controlled-trial
#19
JOURNAL ARTICLE
Takeru Sato, Takumi Aoki, Yuki Ito, Kan Oishi, Masaki Fujishima, Eri Okumura, Kojiro Ishii
BACKGROUND: Cardiac autonomic function (CAF) decreases with aging, and Acanthopanax senticosus Harms (ASH) consumption reportedly induces anti-stress effects. This study aimed to assess the effect of continuous supplementation of ASH on CAF during resting and standing tests in the elderly population. METHODS: This double-blind, randomized controlled trial was conducted in the morning in a laboratory setting and was carried out between June 2017 and July 2017 at Kambaikan, Doshisha University (Karasuma-higashi-iru, Imadegawa-dori, Kamigyo-ku, Kyoto 602-8580, Japan)...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38525189/the-ratio-of-systolic-and-diastolic-pressure-is-associated-with-carotid-and-femoral-atherosclerosis
#20
JOURNAL ARTICLE
Yuanping Wang, Cheng Chen, Qiaofen Lin, Qingling Su, Yiquan Dai, Hongyu Chen, Tianmin He, Xiantao Li, Ruimei Feng, Wuqing Huang, Zhijian Hu, Jun Chen, Shanshan Du, Pingfan Guo, Weimin Ye
BACKGROUND: Although the impact of hypertension on carotid intima-media thickness (IMT) and plaques has been well established, its association with femoral IMT and plaques has not been extensively examined. In addition, the role of the ratio of systolic and diastolic pressure (SDR) in the subclinical atherosclerosis (AS) risk remains unknown. We assessed the relationship between SDR and carotid and femoral AS in a general population. METHODS: A total of 7,263 participants aged 35-74 years enrolled from January 2019 to June 2021 in a southeast region of China were included in a cross-sectional study...
2024: Frontiers in Cardiovascular Medicine
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