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https://www.readbyqxmd.com/read/28814844/comparison-between-parameters-of-muscle-performance-and-inflammatory-biomarkers-of-non-sarcopenic-and-sarcopenic-elderly-women
#1
Lygia Paccini Lustosa, Patrícia Parreira Batista, Daniele Sirineu Pereira, Leani Souza Máximo Pereira, Aline Scianni, Giane Amorim Ribeiro-Samora
BACKGROUND: Sarcopenia is a multifactorial geriatric syndrome with complex interrelationships. Increased plasma levels of inflammatory mediators increase the catabolic stimuli of the musculature, thereby causing a decrease in mass and muscular function. OBJECTIVE: The objective of this study was to compare the performance of the knee extensors test (by isokinetic dynamometer) and plasma levels of interleukin-6 (IL-6) and soluble receptors of tumor necrosis factor alpha (sTNFR1) between sarcopenics and non-sarcopenics community-dwelling elderly women residents of Brazil...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28814401/effects-of-protein-supplementation-combined-with-resistance-exercise-on-body-composition-and-physical-function-in-older-adults-a-systematic-review-and-meta-analysis
#2
Chun-De Liao, Jau-Yih Tsauo, Yen-Tzu Wu, Chin-Pao Cheng, Hui-Chuen Chen, Yi-Ching Huang, Hung-Chou Chen, Tsan-Hon Liou
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a beneficial effect on muscle protein synthesis and can be augmented by protein supplementation (PS). However, whether body weight affects the augmentation of muscular and functional performance in response to PS in older people undergoing RET remains unclear.Objective: This study was conducted to identify the effects of PS on the body composition and physical function of older people undergoing RET...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28796017/sarcopenia-prevalence-and-impact-on-operative-and-oncologic-outcomes-in-the-multimodal-management-of-locally-advanced-esophageal-cancer
#3
Jessie A Elliott, Suzanne L Doyle, Conor F Murphy, Sinead King, Emer M Guinan, Peter Beddy, Narayanasamy Ravi, John V Reynolds
OBJECTIVE: The aim of this article was to study the prevalence and significance of sarcopenia in the multimodal management of locally advanced esophageal cancer (LAEC), and to assess its independent impact on operative and oncologic outcomes. SUMMARY OF BACKGROUND DATA: Sarcopenia in cancer may confer negative outcomes, but its prevalence and impact on modern multimodal regimens for LAEC have not been systematically studied. METHODS: Two hundred fifty-two consecutive patients were studied...
August 8, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28777289/sarcopenia-increases-risk-of-long-term-mortality-in-elderly-patients-undergoing-emergency-abdominal-surgery
#4
Erika L Rangel, Arturo J Rios-Diaz, Jennifer W Uyeda, Manuel Castillo-Angeles, Zara Cooper, Olubode A Olufajo, Ali Salim, Aaron D Sodickson
BACKGROUND: Frailty is associated with poor surgical outcomes in elderly patients but is difficult to measure in the emergency setting. Sarcopenia, or the loss of lean muscle mass, is a surrogate for frailty and can be measured using cross-sectional imaging. We sought to determine the impact of sarcopenia on one-year mortality after emergency abdominal surgery in elderly patients. METHODS: Sarcopenia was assessed in patients ≥70 years old who underwent emergency abdominal surgery at a single hospital from 2006-2011...
August 3, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28762310/sarcopenia-aging-and-prospective-interventional-strategies
#5
Tyler B Waltz, Elayne M Fivenson, Marya Morevati, Chuanhao Li, Kevin G Becker, Vilhelm A Bohr, Evandro Fei Fang
Sarcopenia, or age-related muscle decline, occurs in most organisms and burdens both human health and the healthcare system. As our population ages, additional options for treating sarcopenia are needed. Mitochondrial dysfunction is implicated in the onset of sarcopenia, so therapies directed at improving mitochondrial function in muscle should be considered. Many naturally-occurring compounds, derived from commonly consumed foods, possess anti-sarcopenic effects, such asnicotinamide riboside, tomatidine, and Urolithin A...
July 31, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28760428/influence-of-nutritional-status-in-the-diagnosis-of-sarcopenia-in-nursing-home-residents
#6
Beatriz Lardiés-Sánchez, Alejandro Sanz-París, Javier Pérez-Nogueras, Antonio Serrano-Oliver, María E Torres-Anoro, Alfonso J Cruz-Jentoft
OBJECTIVES: Malnutrition and sarcopenia frequently coexist in elderly patients. The aim of this study was to assess the effect of nutritional status in the diagnosis of sarcopenia in nursing home residents. METHODS: A cross-sectional study was performed with data collected from 339 elderly patients living in five nursing homes. Sarcopenia was defined according to the consensus definition of the European Working Group on Sarcopenia in Older People. Body mass composition was assessed using bioimpedance analysis, handgrip strength using a dynamometer, and physical performance by 5-m gait speed test...
September 2017: Nutrition
https://www.readbyqxmd.com/read/28760111/differences-in-prevalence-of-muscle-wasting-in-patients-receiving-peritoneal-dialysis-per-dual-energy-x-ray-absorptiometry-due-to-variation-in-guideline-definitions-of-sarcopenia
#7
Rachel Hung, Bethany Wong, Gabrielle Goldet, Andrew Davenport
BACKGROUND: Muscle wasting is associated with increased risk for mortality. There is no agreed universal definition for muscle wasting (sarcopenia), and we wished to determine whether using different criteria altered the prevalence in patients treated by peritoneal dialysis. METHODS: We measured lean body and appendicular lean mass indices in 325 outpatients by dual-energy x-ray absorptiometry, comparing muscle mass with that used to define muscle wasting (sarcopenia) by various clinical guideline publications...
August 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28749192/current-review-of-the-sarqol%C3%A2-a-health-related-quality-of-life-questionnaire-specific-to-sarcopenia
#8
Charlotte Beaudart, Jean-Yves Reginster, Anton Geerinck, Médéa Locquet, Olivier Bruyère
Sarcopenia, defined by a progressive and generalized loss of muscle mass and muscle function, is associated with many harmful clinical consequences. Several studies have reported the impact of sarcopenia on health-related quality of life (HRQoL) using generic quality of life (QoL) questionnaires. The results of these observational studies are quite heterogenous. Indeed, generic tools may not be able to detect subtle effects of sarcopenia on QoL. Recently, a sarcopenia-specific HRQoL questionnaire was developed and validated in a population of sarcopenic subjects to more accurately assess the impact of sarcopenia on QoL...
July 27, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28742506/bioimpedance-analysis-vs-dexa-as-a-screening-tool-for-osteosarcopenia-in-lean-overweight-and-obese-caucasian-postmenopausal-females
#9
Melpomeni Peppa, Charikleia Stefanaki, Athanasios Papaefstathiou, Dario Boschiero, George Dimitriadis, George P Chrousos
BACKGROUND-OBJECTIVES: We aimed at evaluating the efficiency of a newly developed, advanced Bioimpedance Analysis (BIA-ACC®) device as a screening tool for determining the degree of obesity and osteosarcopenia in postmenopausal women with normal or decreased bone density determined by Dual-Energy X-Ray absorptiometry (DEXA) in a representative sample of Greek postmenopausal women. METHODS: This is a single-gate cross-sectional study of body composition measured by BIA-ACC® and DEXA...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28739051/effectiveness-of-nutritional-and-exercise-interventions-to-improve-body-composition-and-muscle-strength-or-function-in-sarcopenic-obese-older-adults-a-systematic-review
#10
REVIEW
Christos Theodorakopoulos, Jacklyn Jones, Elaine Bannerman, Carolyn A Greig
Although sarcopenic obesity (SO) poses a major public health concern, a robust approach for the optimization of body composition and strength/function in SO has not yet been established. The purpose of this systematic review was to assess the effectiveness of nutritional (focusing on energy and protein modulation) and exercise interventions, either individually or combined, on body composition and strength/function in older adults with SO. MEDLINE, the Cochrane Central Register of Controlled Trials, CINAHL and SPORTDiscus were searched...
July 2017: Nutrition Research
https://www.readbyqxmd.com/read/28736646/sarcopenia-related-to-neoadjuvant-chemotherapy-and-perioperative-outcomes-in-resected-gastric-cancer-a-multi-institutional-analysis
#11
Katelin A Mirkin, Franklyn E Luke, Alexandra Gangi, Jose M Pimiento, Daniel Jeong, Christopher S Hollenbeak, Joyce Wong
BACKGROUND: This study's objective was to evaluate the change in sarcopenia score following neoadjuvant chemotherapy (NAC) and to correlate both sarcopenia and change in score with perioperative outcomes in patients with advanced resected gastric cancer. METHODS: Multi-institutional analysis of patients with gastric cancer who underwent NAC and resection from 2000-2015 was performed. Demographic and perioperative data were included. Sarcopenia score was defined as CT measurement of total psoas muscle at L3, stratified by height (m)...
June 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28733716/osteosarcopenia-where-bone-muscle-and-fat-collide
#12
REVIEW
H P Hirschfeld, R Kinsella, G Duque
As the world's population ages, the prevalence of chronic diseases increases. Sarcopenia and osteoporosis are two conditions that are associated with aging, with similar risk factors that include genetics, endocrine function, and mechanical factors. Additionally, bone and muscle closely interact with each other not only anatomically, but also chemically and metabolically. Fat infiltration, a phenomenon observed in age-related bone and muscle loss, is highly prevalent and more severe in sarcopenic and osteoporotic subjects...
July 22, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28731551/sarcopenia-and-hospitalisation-costs-in-older-adults-a-cross-sectional-study
#13
Ana C Antunes, Daniela A Araújo, Manuel T Veríssimo, Teresa F Amaral
AIM: The impact of sarcopenia on hospitalisation has been under intense investigation; however, little is known about the association between sarcopenia and their costs among hospitalised patients. The aim of the present study was to quantify the association between sarcopenia and hospitalisation costs among older adults. METHODS: A cross-sectional study was conducted in 201 hospitalised older adults in a general hospital. Sarcopenia was identified according to the European Working Group on Sarcopenia in Older People (EWGSOP) criteria...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28726035/evaluation-of-physical-activity-in-sarcopenic-conditions-of-kidney-transplantation-recipients
#14
Masaaki Yanishi, Hiroyasu Tsukaguchi, Yutaka Kimura, Yuya Koito, Kenji Yoshida, Maiko Seo, Eri Jino, Motohiko Sugi, Hidefumi Kinoshita, Tadashi Matsuda
INTRODUCTION: Sarcopenia is an involuntary decline in skeletal muscle mass, strength, and function that normally proceed with aging but may develop faster under some chronic disease conditions. In this study, we compared the physical activity between sarcopenia and non-sarcopenia subgroups in kidney transplant recipients. METHODS: Fifty-eight recipients (42 males and 16 females) were enrolled in this study. Mean age of the recipients was 46.6 ± 12.7 years. Mean duration of dialysis was 2...
July 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28711604/an-animal-model-of-co-existing-sarcopenia-and-osteoporotic-fracture-in-senescence-accelerated-mouse-prone-8-samp8
#15
Ning Zhang, Simon Kwoon Ho Chow, Kwok Sui Leung, Ho Hin Lee, Wing Hoi Cheung
Sarcopenia and osteoporotic fracture are common aging-related musculoskeletal problems. Recent evidences report that osteoporotic fracture patients showed high prevalence of sarcopenia; however, current clinical practice basically does not consider sarcopenia in the treatment or rehabilitation of osteoporotic fracture. There is almost no report studying the relationship of the co-existing of sarcopenia and osteoporotic fracture healing. In this study, we validated aged senescence accelerated mouse prone 8 (SAMP8) and senescence accelerated mouse resistant 1 (SAMR1) as animal models of senile osteoporosis with/without sarcopenia...
July 12, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28710147/dietary-guidelines-for-breast-cancer-patients-a-critical-review
#16
REVIEW
Ana Teresa Limon-Miro, Veronica Lopez-Teros, Humberto Astiazaran-Garcia
Current dietary guidelines for breast cancer patients (BCPs) fail to address adequate dietary intakes of macro- and micronutrients that may improve patients' nutritional status. This review includes information from the PubMed and Biomed Central databases over the last 15 y concerning dietary guidelines for BCPs and the potential impact of a personalized, nutrient-specific diet on patients' nutritional status during and after antineoplastic treatment. Results indicated that BCPs should receive a nutritional assessment immediately after diagnosis...
July 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28702888/cushing-s-syndrome-a-model-for-sarcopenic-obesity
#17
Michael Drey, Christina M Berr, Martin Reincke, Julia Fazel, Jochen Seissler, Jochen Schopohl, Martin Bidlingmaier, Stefanie Zopp, Nicole Reisch, Felix Beuschlein, Andrea Osswald, Ralf Schmidmaier
PURPOSE: Obesity and its metabolic impairments are discussed as major risk factors for sarcopenia leading to sarcopenic obesity. Cushing's syndrome is known to be associated with obesity and muscle atrophy. We compared Cushing's syndrome with matched obese controls regarding body composition, physical performance, and biochemical markers to test the hypothesis that Cushing's syndrome could be a model for sarcopenic obesity. METHODS: By propensity score matching, 47 controls were selected by body mass index and gender as obese controls...
July 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28702214/involvement-of-oxidative-stress-in-atherosclerosis-development-in-subjects-with-sarcopenic-obesity
#18
R Nakano, N Takebe, M Ono, M Hangai, R Nakagawa, S Yashiro, T Murai, K Nagasawa, Y Takahashi, J Satoh, Y Ishigaki
No abstract text is available yet for this article.
June 2017: Obesity Science & Practice
https://www.readbyqxmd.com/read/28699003/sarcopenia-is-an-independent-predictor-of-complications-after-colorectal-cancer-surgery
#19
Ryota Nakanishi, Eiji Oki, Shun Sasaki, Kosuke Hirose, Tomoko Jogo, Keitaro Edahiro, Shotaro Korehisa, Daisuke Taniguchi, Kensuke Kudo, Junji Kurashige, Masahiko Sugiyama, Yuichiro Nakashima, Kippei Ohgaki, Hiroshi Saeki, Yoshihiko Maehara
PURPOSE: The significance of sarcopenia after colorectal cancer (CRC) resection has only been discussed with relatively small samples or short follow-up periods. This study aimed to clarify the clinical significance of sarcopenia in a large-sample study. METHODS: We retrospectively analyzed the relationship between sarcopenia and clinical factors, surgical outcomes, and the survival in 494 patients who underwent CRC surgery between 2004 and 2013. Sarcopenia was defined based on the sex-specific skeletal muscle mass index measured by preoperative computed tomography...
July 11, 2017: Surgery Today
https://www.readbyqxmd.com/read/28698349/a-pilot-randomised-controlled-trial-of-a-periodised-resistance-training-and-protein-supplementation-intervention-in-prostate-cancer-survivors-on-androgen-deprivation-therapy
#20
Jacqueline L Kiwata, Tanya B Dorff, E Todd Schroeder, George J Salem, Christianne J Lane, Judd C Rice, Mitchell E Gross, Christina M Dieli-Conwright
INTRODUCTION: Prostate cancer survivors (PCS) receiving androgen deprivation therapy (ADT) experience deleterious side effects such as unfavourable changes in cardiometabolic factors that lead to sarcopenic obesity and metabolic syndrome (MetS). While loss of lean body mass (LBM) compromises muscular strength and quality of life, MetS increases the risk of cardiovascular disease and may influence cancer recurrence. Exercise can improve LBM and strength, and may serve as an alternative to the pharmacological management of MetS in PCS on ADT...
July 10, 2017: BMJ Open
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