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https://www.readbyqxmd.com/read/28644887/sarcopenia-is-a-predictive-factor-for-intestinal-resection-in-admitted-patients-with-crohn-s-disease
#1
Shigeki Bamba, Masaya Sasaki, Azusa Takaoka, Kenichiro Takahashi, Hirotsugu Imaeda, Atsushi Nishida, Osamu Inatomi, Mitsushige Sugimoto, Akira Andoh
The relationship between skeletal muscle volume and the prognosis of patients with inflammatory bowel disease (IBD) remains undetermined. We conducted a retrospective study of 72 IBD patients who were admitted to the hospital due to disease exacerbation. We enrolled IBD patients who had undergone abdominal computed tomography and assessed the nutritional indices, such as the Onodera's prognostic nutritional index (O-PNI) and the controlling nutritional status (CONUT) index. The L3 skeletal muscle index (SMI), which is the ratio of the cross-sectional area of skeletal muscles at the level of the third lumbar (L3) vertebra to the height squared, was used to identify sarcopenia...
2017: PloS One
https://www.readbyqxmd.com/read/28629717/sarcopenia-screened-by-the-sarc-f-questionnaire-and-physical-performances-of-elderly-women-a-cross-sectional-study
#2
Yves Rolland, Charlotte Dupuy, Gabor Abellan Van Kan, Matteo Cesari, Bruno Vellas, Marie Faruch, Cedric Dray, Philipe de Souto Barreto
OBJECTIVES: Screening for sarcopenia in daily practice can be challenging. Our objective was to explore whether the SARC-F questionnaire is a valid screening tool for sarcopenia (defined by the Foundation for the National Institutes of Health [FNIH] criteria). Moreover, we evaluated the physical performance of older women according to the SARC-F questionnaire. DESIGN: Cross-sectional study. PARTICIPANTS: Data from the Toulouse and Lyon EPIDémiologie de l'OStéoporose study (EPIDOS) on 3025 women living in the community (mean age: 80...
June 16, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28615264/is-the-whole-not-greater-than-the-sum-of-its-parts-the-case-of-sarcopenic-obesity
#3
John A Batsis, Summer B Cook
No abstract text is available yet for this article.
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28604415/sarcopenia-is-a-predictor-of-surgical-morbidity-in-inflammatory-bowel-disease
#4
Mark Pedersen, John Cromwell, Peter Nau
BACKGROUND: Sarcopenia is associated with an increased risk of operative morbidity and mortality. The impact of sarcopenia in inflammatory bowel disease (IBD) has not been evaluated. This study assessed the role of sarcopenia on operative outcomes in IBD. METHODS: A retrospective review of American College of Surgeons National Surgical Quality Improvement Program data of patients with IBD was completed. Records were abstracted for comorbidities and perioperative complications...
June 9, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28600505/malnutrition-sarcopenia-syndrome-predicts-mortality-in-hospitalized-older-patients
#5
Xiaoyi Hu, Lei Zhang, Haozhong Wang, Qiukui Hao, Birong Dong, Ming Yang
A new term, malnutrition-sarcopenia syndrome (MSS), was recently coined to describe the clinical presentation of both malnutrition and sarcopenia. The aim of this study was to investigate the association between MSS and long-term mortality in older inpatients. We conducted a prospective study in acute geriatric wards of two local hospitals in China. Muscle mass and malnutrition were estimated by anthropometric measures and the Mini Nutritional Assessment (MNA). Of the 453 participants, 14 (3.1%) had sarcopenia with normal nutrition, 139 (30...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28597150/erratum-to-sarcopenic-overweight-is-associated-with-early-acute-limiting-toxicity-of-anti-pd1-checkpoint-inhibitors-in-melanoma-patients
#6
Valentine Heidelberger, François Goldwasser, Nora Kramkimel, Anne Jouinot, Olivier Huillard, Pascaline Boudou-Rouquette, Johan Chanal, Jennifer Arrondeau, Nathalie Franck, Jérôme Alexandre, Benoît Blanchet, Karen Leroy, Marie-Françoise Avril, Nicolas Dupin, Sélim Aractingi
No abstract text is available yet for this article.
June 9, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28591061/effects-of-elastic-resistance-exercise-on-body-composition-and-physical-capacity-in-older-women-with-sarcopenic-obesity-a-consort-compliant-prospective-randomized-controlled-trial
#7
Chun-De Liao, Jau-Yih Tsauo, Li-Fong Lin, Shih-Wei Huang, Jan-Wen Ku, Lin-Chuan Chou, Tsan-Hon Liou
BACKGROUND: Sarcopenia is associated with loss of muscle mass and an increased risk of physical disability in elderly people. However, the prevalence of sarcopenia has increased in obese elderly populations. The purpose of this study was to identify the clinical efficacy of elastic resistance exercise training (RET) in patients with sarcopenic obesity. METHODS: This study was conducted at the rehabilitation center of a university-based teaching hospital and was designed as a prospective and randomized controlled trial with an intention-to-treat analysis...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28578881/increased-myogenic-and-protein-turnover-signaling-in-skeletal-muscle-of-chronic-obstructive-pulmonary-disease-patients-with-sarcopenia
#8
Anita E M Kneppers, Ramon C J Langen, Harry R Gosker, Lex B Verdijk, Nanca Cebron Lipovec, Pieter A Leermakers, Marco C J M Kelders, Chiel C de Theije, Daniel Omersa, Mitja Lainscak, Annemie M W J Schols
BACKGROUND: Sarcopenia was recently recognized as an independent condition by an International Classification of Diseases, Tenth Revision, Clinical Modification code, and is a frequently observed comorbidity in chronic obstructive pulmonary disease (COPD). Muscle mass is primarily dictated by the balance between protein degradation and synthesis, but their relative contribution to sarcopenia is unclear. OBJECTIVE: We aimed to assess potential differential molecular regulation of protein degradation and synthesis, as well as myogenesis, in the skeletal muscle of COPD patients with and without sarcopenia...
May 31, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28577161/morphological-and-qualitative-characteristics-of-the-quadriceps-muscle-of-community-dwelling-older-adults-based-on-ultrasound-imaging-classification-using-latent-class-analysis
#9
Hisashi Kawai, Takeshi Kera, Ryo Hirayama, Hirohiko Hirano, Yoshinori Fujiwara, Kazushige Ihara, Motonaga Kojima, Shuichi Obuchi
BACKGROUND: Muscle thickness and echo intensity measured using ultrasound imaging represent both increased muscle volume and connective tissue accumulation. In combination, these ultrasound measurements can be utilized for assessing sarcopenia in community-dwelling older adults. AIMS: This study aimed to determine whether morphological and qualitative characteristics classified by quadriceps muscle thickness and echo intensity measured using ultrasound are associated with muscle strength, physical function, and sarcopenia in community-dwelling older adults...
June 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28542531/new-diagnostic-index-for-sarcopenia-in-patients-with-cardiovascular-diseases
#10
Haruhito Harada, Hisashi Kai, Rei Shibata, Hiroshi Niiyama, Yasuhiro Nishiyama, Toyoaki Murohara, Noriko Yoshida, Atsushi Katoh, Hisao Ikeda
BACKGROUND: Sarcopenia is an aging and disease-related syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, with the risk of frailty and poor quality of life. Sarcopenia is diagnosed by a decrease in skeletal muscle index (SMI) and reduction of either handgrip strength or gait speed. However, measurement of SMI is difficult for general physicians because it requires special equipment for bioelectrical impedance assay or dual-energy X-ray absorptiometry...
2017: PloS One
https://www.readbyqxmd.com/read/28542196/using-relative-handgrip-strength-to-identify-children-at-risk-of-sarcopenic-obesity
#11
Michal Steffl, Jan Chrudimsky, James J Tufano
Identifying children at risk of developing childhood sarcopenic obesity often requires specialized equipment and costly testing procedures, so cheaper and quicker methods would be advantageous, especially in field-based settings. The purpose of this study was to determine the relationships between the muscle-to-fat ratio (MFR) and relative handgrip strength, and to determine the ability of handgrip strength relative to body mass index (grip-to-BMI) to identify children who are at risk of developing sarcopenic obesity...
2017: PloS One
https://www.readbyqxmd.com/read/28539380/sarcopenic-obesity-weight-loss-and-mortality-the-english-longitudinal-study-of-ageing
#12
Mark Hamer, Gary O'Donovan
Background: Age-related sarcopenia describes the loss of muscle strength and often accompanies an increase in adiposity in the elderly.Objective: We examined the association of sarcopenic obesity and changes in muscle strength and weight with the risk of mortality.Design: Participants (n = 6864) were community-dwelling men and women (45.6% men; 54.4% women; mean ± SD age: 66.2 ± 9.5 y) from the English Longitudinal Study of Ageing. Handgrip strength and body mass index (BMI; in kg/m(2)) were measured at baseline and at a 4-y follow-up...
May 24, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28539168/effectiveness-of-nutritional-supplementation-on-sarcopenia-and-recovery-in-hip-fracture-patients-a-multi-centre-randomized-trial
#13
Vincenzo Malafarina, Francisco Uriz-Otano, Concetta Malafarina, J Alfredo Martinez, M Angeles Zulet
BACKGROUND AND OBJECTIVES: Functional deterioration and reduced mobility in elderly patients with a hip fracture are associated with a loss of both muscle mass and function (sarcopenia). The aim of this study was to assess whether oral nutritional supplementation (ONS) improves muscle mass and nutritional markers (BMI, proteins) in elderly patients with hip fracture. METHODS: Patients aged 65 years and over with hip fractures admitted to either of two rehabilitation facilities were included...
July 2017: Maturitas
https://www.readbyqxmd.com/read/28537342/assessing-the-risk-of-sarcopenia-in-the-elderly-the-mini-sarcopenia-risk-assessment-msra-questionnaire
#14
A P Rossi, R Micciolo, S Rubele, F Fantin, C Caliari, E Zoico, G Mazzali, E Ferrari, S Volpato, M Zamboni
OBJECTIVES: to validate the MSRA questionnaire proposed as prescreening tool for sarcopenia, in a population of community-dwelling elderly subjects. DESIGN: observational study. SETTING: community dwelling elderly subjects. PARTICIPANTS: 274 community dwelling elderly subjects, 177 women and 97 men, aged 66-78 years. MEASUREMENTS: Based on EWGSOP diagnostic criteria subjects were classified as sarcopenic and non-sarcopenic...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28531567/impact-of-body-composition-parameters-on-clinical-outcomes-in-patients-with-metastatic-castrate-resistant-prostate-cancer-treated-with-docetaxel
#15
Samantha J Cushen, Derek G Power, Kevin P Murphy, Ray McDermott, Brendan T Griffin, Marvin Lim, Louise Daly, Peter MacEneaney, Kathleen O' Sullivan, Carla M Prado, Aoife M Ryan
BACKGROUND: Body composition may influence clinical outcomes of certain chemotherapeutic agents. We examined the prognostic significance of skeletal muscle mass and adipose tissue on docetaxel toxicity and overall survival in patients with metastatic castrate resistant prostate cancer (mCRPC). METHODS: A retrospective review of patients medical records with mCRPC, treated with docetaxel was conducted. Body composition parameters (skeletal muscle mass, muscle attenuation [MA], visceral and subcutaneous adipose tissue) were measured at L3 by computed tomography (CT) and defined using previously established cut points...
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28528340/evaluation-of-hypocaloric-diet-with-protein-supplementation-in-middle-aged-sarcopenic-obese-women-a-pilot-study
#16
Rosa Sammarco, Maurizio Marra, Maria Luisa Di Guglielmo, Marianna Naccarato, Franco Contaldo, Eleonora Poggiogalle, Lorenzo Maria Donini, Fabrizio Pasanisi
OBJECTIVE: The aim of this study was to evaluate the efficacy of a nutritional program, which is characterized by a different modulation of proteins, in adult patients with sarcopenic obesity. METHODS: We studied 18 obese women aged 41-74 years. Obesity was diagnosed as fat mass > 34.8% and sarcopenia was defined when lean body mass was <90% of the subject's ideal fat free mass. All subjects were randomly assigned to different nutritional interventions: Hypocaloric diet plus placebo (A) and hypocaloric high-protein diet (1...
May 20, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28523992/nutrition-and-exercise-in-sarcopenia
#17
Stephen D Anton, Azumi Hida, Robert Mankowski, Andrew Layne, Lawrence Solberg, Arch G Mainous, Thomas W Buford
Sarcopenia is a debilitating condition that involves loss of muscle mass and function, which affects virtually everyone as they age, and can lead to frailty and ultimately disability. In growing recognition of the importance of both muscle strength and muscle mass relative to body size in contributing to functional decline, recent definitions have now incorporated grip strength and a correction for body mass as part of the key criteria that define sarcopenia. With this new definition, a much larger population of older adults are now at risk of sarcopenia...
December 27, 2016: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28506965/explaining-the-obesity-paradox-the-association-between-body-composition-and-colorectal-cancer-survival-c-scans-study
#18
Bette J Caan, Jeffrey A Meyerhardt, Candyce H Kroenke, Stacey Alexeeff, Jingjie Xiao, Erin Weltzien, Elizabeth Cespedes Feliciano, Adrienne L Castillo, Charles P Quesenberry, Marilyn L Kwan, Carla M Prado
Background: Body composition may partially explain the U-shaped association between body mass index (BMI) and colorectal cancer survival.Methods: Muscle and adiposity at colorectal cancer diagnosis and survival were examined in a retrospective cohort using Kaplan-Meier curves, multivariable Cox regression, and restricted cubic splines in 3,262 early-stage (I-III) male (50%) and female (50%) patients. Sarcopenia was defined using optimal stratification and sex- and BMI-specific cut points. High adiposity was defined as the highest tertile of sex-specific total adipose tissue (TAT)...
May 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28501109/sarcopenia-a-new-predictor-of-postoperative-complications-for-elderly-gastric-cancer-patients-who-underwent-radical-gastrectomy
#19
Chong-Jun Zhou, Feng-Min Zhang, Fei-Yu Zhang, Zhen Yu, Xiao-Lei Chen, Xian Shen, Cheng-Le Zhuang, Xiao-Xi Chen
BACKGROUND: A geriatric assessment is needed to identify high-risk elderly patients with gastric cancer. However, the current geriatric assessment has been considered to be either time-consuming or subjective. The present study aimed to investigate the predictive effect of sarcopenia on the postoperative complications for elderly patients who underwent radical gastrectomy. MATERIALS AND METHODS: We conducted a prospective study of patients who underwent radical gastrectomy from August 2014 to December 2015...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28490866/nonpharmacological-interventions-to-treat-physical-frailty-and-sarcopenia-in-older-patients-a-systematic-overview-the-senator-project-ontop-series
#20
REVIEW
Isabel Lozano-Montoya, Andrea Correa-Pérez, Iosief Abraha, Roy L Soiza, Antonio Cherubini, Denis O'Mahony, Alfonso J Cruz-Jentoft
BACKGROUND: Physical frailty (PF) and sarcopenia are predictors of negative health outcomes such as falls, disability, hospitalization, and death. Some systematic reviews (SRs) have been published on different nonpharmacological treatments of frailty and sarcopenia using heterogeneous definitions of them. OBJECTIVE: To critically appraise the evidence from SRs of the primary studies on nonpharmacological interventions to treat PF (defined by Fried's frailty phenotype) and sarcopenia (defined by the EWGSOP) in older patients...
2017: Clinical Interventions in Aging
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