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https://www.readbyqxmd.com/read/29343989/comparison-of-the-performance-of-five-screening-methods-for-sarcopenia
#1
Médéa Locquet, Charlotte Beaudart, Jean-Yves Reginster, Jean Petermans, Olivier Bruyère
Background: Sarcopenia leads to serious adverse health consequences. There is a dearth of screening tools for this condition, and performances of these instruments have rarely been evaluated. Our aim was to compare the performance of five screening tools for identifying elders at risk of sarcopenia against five diagnostic definitions. Subjects and methods: We gathered cross-sectional data of elders from the SarcoPhAge ("Sarco"penia and "Ph"ysical Impairment with Advancing "Age") study...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29343219/the-preliminary-effect-of-whole-body-vibration-intervention-on-improving-the-skeletal-muscle-mass-index-physical-fitness-and-quality-of-life-among-older-people-with-sarcopenia
#2
Shu-Fang Chang, Pei-Chen Lin, Rong-Sen Yang, Rea-Jeng Yang
BACKGROUND: Studies have shown that sarcopenia easily leads to difficulty moving, disability, and poor quality of life. However, researches on the use of whole-body vibration for older adults with sarcopenia living in institutions have been lacking. Therefore, the main objective of the present study was to investigate the effect of whole-body vibration intervention on improving the skeletal muscle mass index, physical fitness, and quality of life of older adults with sarcopenia living in institutions...
January 17, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29318756/loss-of-skeletal-muscle-during-systemic-chemotherapy-is-prognostic-of-poor-survival-in-patients-with-foregut-cancer
#3
Louise E Daly, Éadaoin B Ní Bhuachalla, Derek G Power, Samantha J Cushen, Karl James, Aoife M Ryan
BACKGROUND: Malnutrition, weight loss, and muscle wasting are common in patients with foregut cancers (oesophagus, stomach, pancreas, liver, and bile ducts) and are associated with adverse clinical outcomes. However, little is known about the changes in body composition that occur in these patients during chemotherapy and its impacts clinical outcomes. PATIENTS AND METHODS: A prospective study of adult foregut cancer patients undergoing chemotherapy between 2012 and 2016 was conducted...
January 9, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29312971/impact-of-sarcopenic-overweight-on-the-outcomes-after-living-donor-liver-transplantation
#4
Ahmed Hammad, Toshimi Kaido, Yuhei Hamaguchi, Shinya Okumura, Atsushi Kobayashi, Hisaya Shirai, Naoko Kamo, Shintaro Yagi, Shinji Uemoto
Background: The effect of body composition disturbances has been recently in focus. Sarcopenic obesity, a co-occurrence of low muscle mass and high body fat was reportedly predictive of high mortality in patients with cirrhosis. However, the impact of the interacting sarcopenia and overweight on the outcomes after liver transplantation is still unclear. Methods: We evaluated 200 patients undergoing adult-to-adult living donor liver transplantation at our institution between January 2008 and November 2013 classified according to BMI and psoas muscle index (PMI) on admission to transplant into 4 subgroups; sarcopenic overweight (SO), sarcopenic non-overweight (SN), non-sarcopenic overweight and non-sarcopenic non-overweight (NN)...
December 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29310892/sarcopenia-is-not-associated-with-morbidity-mortality-or-recurrence-after-esophagectomy-for-cancer
#5
Steve R Siegal, James P Dolan, Elizabeth N Dewey, Alexander R Guimaraes, Brandon H Tieu, Paul H Schipper, John G Hunter
BACKGROUND: Sarcopenia is associated with increased morbidity and mortality in hepatic, pancreatic and colorectal cancer. We examined the effect of sarcopenia on morbidity, mortality, and recurrence after resection for esophageal cancer. METHODS: Retrospective review of consecutive esophagectomies from 2010 to 2015. Computed tomography studies were analyzed for sarcopenia. Morbidity was analyzed using Fischer's test and survival data with Kaplan Meier curves. RESULTS: The sarcopenic group (n = 127) had lower BMI, later stage disease, and higher incidence of neoadjuvant radiation than those without sarcopenia (n = 46)...
January 4, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29308681/therapeutic-considerations-of-sarcopenia-in-heart-failure-patients
#6
Masakazu Saitoh, Nicole Ebner, Stephan von Haehling, Stefan D Anker, Jochen Springer
Sarcopenia is a common feature, and affects 20-47% of patients with heart failure (HF). Sarcopenia is also an independent predictor of impaired functional capacity, even after adjusting for clinical relevant variables, which is associated with adverse outcome in patients with HF. Areas covered: Several different pathophysiological pathways are involved in sarcopenic processes including altered nutrient intake and absorption, hormonal factor, inflammatory processes, oxidative stress, cellular proteolysis, and unhealthy lifestyle...
January 7, 2018: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29304744/a-randomised-controlled-intervention-study-investigating-the-efficacy-of-carotenoid-rich-fruits-and-vegetables-and-extra-virgin-olive-oil-on-attenuating-sarcopenic-symptomology-in-overweight-and-obese-older-adults-during-energy-intake-restriction-protocol-paper
#7
Anthony Villani, Hattie Wright, Gary Slater, Jonathan Buckley
BACKGROUND: Weight loss interventions have not been advocated for overweight/obese older adults due to potential loss of skeletal muscle and strength impacting on physical function with potential loss of independence. Carotenoids and polyphenols are inversely associated with sarcopenic symptomology. This paper reports the protocol of a study evaluating the efficacy of a high-protein, energy restricted diet rich in carotenoids and polyphenols on body composition, muscle strength, physical performance and quality of life in overweight and obese older adults...
January 5, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29302020/muscle-function-decline-and-mitochondria-changes-in-middle-age-precede-sarcopenia-in-mice
#8
Andrea Del Campo, Ignacio Contreras-Hernández, Mauricio Castro-Sepúlveda, Cristian A Campos, Reinaldo Figueroa, María Florencia Tevy, Verónica Eisner, Mariana Casas, Enrique Jaimovich
Sarcopenia is the degenerative loss of muscle mass and strength with aging. Although a role of mitochondrial metabolism in muscle function and in the development of many diseases has been described, the role of mitochondrial topology and dynamics in the process of muscle aging is not fully understood. This work shows a time line of changes in both mitochondrial distribution and skeletal muscle function during mice lifespan. We isolated muscle fibers from flexor digitorum brevis of mice of different ages. A fusion-like phenotype of mitochondria, together with a change in orientation perpendicular to the fiber axis was evident in the Adult group compared to Juvenile and Older groups...
January 4, 2018: Aging
https://www.readbyqxmd.com/read/29300839/associations-of-sarcopenia-definitions-and-their-components-with-the-incidence-of-recurrent-falling-and-fractures-the-longitudinal-aging-study-amsterdam
#9
Laura A Schaap, Natasja M van Schoor, Paul Lips, Marjolein Visser
Background: The aim was to investigate the associations of sarcopenia as defined by European Working Group on Sarcopenia in Older People (EWGSOP) and Foundation for the National Institutes of Health (FNIH) Sarcopenia Project, and their underlying components, with the incidence of recurrent falling and fractures. Methods: In 498 older older men and women (mean age 75.2 (SD 6.4)) from the Longitudinal Aging Study Amsterdam (LASA), the sarcopenia components lean mass (DXA), handgrip strength (handheld dynamometer) and gait speed were measured...
December 30, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29290364/association-of-sarcopenic-obesity-predicted-by-anthropometric-measurements-and-24-y-all-cause-mortality-in-elderly-men-the-kuakini-honolulu-heart-program
#10
Kiyoshi Sanada, Randi Chen, Bradley Willcox, Tomoyuki Ohara, Aida Wen, Cody Takenaka, Kamal Masaki
OBJECTIVE: The aim of this study was to investigate the association between anthropometric measurements of sarcopenic obesity and all-cause mortality. METHODS: The study included 2309 Japanese-American men ages 71 to 93 y. Mortality data were available for up to 24 y of follow-up. Sarcopenic obesity defined by three patterns of obesity indexes (body mass index [BMI], percent body fat [%BF] and waist circumference [WC]) and skeletal muscle index estimated by anthropometric measurements...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29290349/dxa-assessed-changes-in-body-composition-in-obese-women-following-two-different-weight-loss-programs
#11
Federico Ponti, Valentina Soverini, Andrea Plazzi, Maria Pilar Aparisi Gómez, Daniele Mercatelli, Giuseppe Guglielmi, Giuseppe Battista, Giulio Marchesini, Alberto Bazzocchi
OBJECTIVE: Changes in body composition during weight loss programs might have a significant effect on long-term results. The aim of this study was to test these changes by dual energy x-ray absorptiometry (DXA) in obese women enrolled into two different weight loss medical programs. METHODS: We prospectively studied 71 women assigned to either an intensive 3-mo cognitive-behavioral therapy (CBT) or a 1-mo nutritional counseling plan (NCP). All patients underwent DXA whole-body scan before treatment and after 3, 6, and 12 mo...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29289518/the-association-between-sarcopenia-and-oncologic-outcomes-after-radical-prostatectomy
#12
Ross J Mason, Stephen A Boorjian, Bimal Bhindi, Laureano Rangel, Igor Frank, R Jeffrey Karnes, Matthew K Tollefson
PURPOSE: Sarcopenia is associated with inferior perioperative and oncologic outcomes in patients undergoing surgery for multiple malignancies. The purpose of this study was to evaluate the association between sarcopenia and outcomes after radical prostatectomy (RP) for men with prostate cancer. PATIENTS AND METHODS: Using a representative computed tomographic image from the L3 level, preoperative skeletal muscle indices (SMI) calculated for 698 patients who underwent RP between 2007 and 2010...
December 6, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29287693/ultrasonography-to-measure-swallowing-muscle-mass-and-quality-in-older-patients-with-sarcopenic-dysphagia
#13
Nami Ogawa, Takashi Mori, Ichiro Fujishima, Hidetaka Wakabayashi, Masataka Itoda, Kenjiro Kunieda, Takashi Shigematsu, Shinta Nishioka, Haruka Tohara, Minoru Yamada, Sumito Ogawa
BACKGROUND: Sarcopenic dysphagia is characterized by difficulty swallowing due to a loss of whole-body skeletal and swallowing muscle mass and function. However, no study has reported on swallowing muscle mass and quality in patients with sarcopenic dysphagia. OBJECTIVE: To compare the differences in swallowing muscle mass and quality between sarcopenic and nonsarcopenic dysphagia. METHOD: A cross-sectional study was performed in 55 older patients, who had been recommended to undergo dysphagia assessment and/or rehabilitation...
December 26, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29277040/associations-of-components-of-sarcopenic-obesity-with-bone-health-and-balance-in-older-adults
#14
David Scott, Catherine Shore-Lorenti, Lachlan McMillan, Jakub Mesinovic, Ross A Clark, Alan Hayes, Kerrie M Sanders, Gustavo Duque, Peter R Ebeling
OBJECTIVES: To determine characteristics of sarcopenic obesity that are independently associated with bone health and balance in older adults. STUDY DESIGN: Cross-sectional study of 168 community-dwelling older adults (mean age 67.7 ± 8.4 years; 55% women). MAIN OUTCOME MEASURES: Appendicular lean mass (ALM), whole-body areal BMD (aBMD) and body fat percentage were assessed by dual-energy X-ray absorptiometry. Peripheral quantitative computed tomography assessed muscle density and cortical volumetric BMD (vBMD), area, thickness, and strength-strain index (SSI) at 66% tibial length...
December 16, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29276063/is-sarcopenia-and-sarcopenic-obesity-associated-with-clinical-and-pathological-outcomes-in-patients-undergoing-radical-nephroureterectomy
#15
Neil J Kocher, Syed Jafri, Samyuktha Balabhadra, Erik Lehman, Jacob Gardner, Kanupriya Vijay, Nabeel Sarwani, Jay D Raman
PURPOSE: To investigate the association between sarcopenia and sarcopenic obesity on clinical, perioperative, and oncologic outcomes in patients with upper-tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy (RNU). METHODS: Retrospective review of our institutional UTUC database was performed to identify all patients who underwent radical nephroureterectomy from 2002-2016. Skeletal Muscle Index (SMI) was measured at the L3 vertebral level and standardized according to patient height (cm2/m2)...
December 21, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29260401/the-impact-of-post-resistance-exercise-protein-consumption-on-subsequent-appetite-and-daily-energy-intake-of-sarcopenic-older-men-a-pilot-study
#16
Mathieu Maltais, Morgane Du Bois-Dit-Bonclaude, Taha Amamou, Eléonor Riesco, Isabelle J Dionne
BACKGROUND: Because of its satiating effect, it has been widely purported that a high-protein beverage may reduce subsequent appetite and food intake in healthy aged individuals, therefore annihilating any supplemental effect. AIMS: The goal of the study was to examine the impact of a post-exercise protein supplement from dairy products in the hours following resistance exercise on subsequent energy intake, sensation of hunger, appetite and satiety in sarcopenic older men...
December 19, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29234200/nutrition-and-muscle-in-cirrhosis
#17
REVIEW
Anil C Anand
As the cirrhosis progresses, development of complication like ascites, hepatic encephalopathy, variceal bleeding, kidney dysfunction, and hepatocellular carcinoma signify increasing risk of short term mortality. Malnutrition and muscle wasting (sarcopenia) is yet other complications that negatively impact survival, quality of life, and response to stressors, such as infection and surgery in patients with cirrhosis. Conventionally, these are not routinely looked for, because nutritional assessment can be a difficult especially if there is associated fluid retention and/or obesity...
December 2017: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29234165/short-physical-performance-battery-for-cardiovascular-disease-inpatients-implications-for-critical-factors-and-sarcopenia
#18
Tomohiro Yasuda, Toshiaki Nakajima, Tatsuya Sawaguchi, Naohiro Nozawa, Tomoe Arakawa, Reiko Takahashi, Yuta Mizushima, Satoshi Katayanagi, Kazuhisa Matsumoto, Shigeru Toyoda, Teruo Inoue
We examined the relationship between Short Physical Performance Battery (SPPB) and clinical and laboratory factors and the effect of sarcopenia and sarcopenic obesity (SO) on clinical and laboratory factors for cardiovascular disease (CVD) inpatients. CVD male (n = 318) and female (n = 172) inpatients were recruited. A stepwise multiple-regression analysis was performed to predict total SPPB scores and assess clinical and laboratory factors (physical characteristics, functional and morphological assessments, etc...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29231963/body-composition-in-long-term-survivors-of-acute-lymphoblastic-leukemia-diagnosed-in-childhood-and-adolescence-a-focus-on-sarcopenic-obesity
#19
Christopher J C Marriott, Lesley F Beaumont, Troy H Farncombe, Amy N Cranston, Uma H Athale, Valerie N Yakemchuk, Colin E Webber, Ronald D Barr
BACKGROUND: The late effects of treatment for acute lymphoblastic leukemia (ALL) include disordered body composition, especially obesity. Less attention has been focused on the loss of skeletal muscle mass (SMM) and the combined morbidity of sarcopenic obesity. METHODS: A cross-sectional study of body composition was undertaken via dual-energy x-ray absorptiometry in 75 long-term survivors of ALL (more than 10 years after the diagnosis). Measures were obtained of the fat mass (FM), fat-free mass (equivalent to the lean body mass [LBM]), and whole-body bone mineral content...
December 12, 2017: Cancer
https://www.readbyqxmd.com/read/29217429/association-of-platelet-count-with-sarcopenic-obesity-in-postmenopausal-women-a-nationwide-population-based-study
#20
Woo-Jin Park, Dong-Hyuk Jung, Ji-Won Lee, Jae-Yong Shim, Yu-Jin Kwon
OBJECTIVES: The aim of this study was to examine the relationship between platelet count and sarcopenic obesity in postmenopausal women. METHOD: This cross-sectional study was conducted using nationally representative data. A total of 2810 postmenopausal women who participated in the 2008-2011 Korea National Health and Nutrition Examination Survey were included in this study. Sarcopenic obesity was defined by a sarcopenia criterion and an obesity criterion. Platelet counts were divided into quartiles as follows: Q, 150-222; Q2, 223-257; Q3, 258-294, and Q4, 295-450 (103/μl)...
December 5, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
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