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Dynapenia

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https://www.readbyqxmd.com/read/29421778/prevalence-of-sarcopenia-and-dynapenia-and-their-determinants-in-iranian-peritoneal-dialysis-patients
#1
Atefeh As'habi, Iraj Najafi, Hadi Tabibi, Mehdi Hedayati
INTRODUCTION: Uremic sarcopenia and dynapenia are prevalent in chronic kidney disease patients, including dialysis patients. The present study was designed to determine the prevalence of sarcopenia and dynapenia and their determinants in peritoneal dialysis (PD) patients in Tehran, Iran. MATERIALS AND METHODS: All eligible PD patients at the peritoneal dialysis centers of Tehran were included in this cross-sectional study. Skeletal muscle mass and muscle strength were assessed using bioelectrical impedance analysis and hand grip strength, respectively...
January 2018: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29368427/physical-activity-unveils-the-relationship-between-mitochondrial-energetics-muscle-quality-and-physical-function-in-older-adults
#2
Giovanna Distefano, Robert A Standley, Xiaolei Zhang, Elvis A Carnero, Fanchao Yi, Heather H Cornnell, Paul M Coen
BACKGROUND: The concept of mitochondrial dysfunction in ageing muscle is highly controversial. In addition, emerging evidence suggests that reduced muscle oxidative capacity and efficiency underlie the aetiology of mobility loss in older adults. Here, we hypothesized that studying well-phenotyped older cohorts across a wide range of physical activity would unveil a range of mitochondrial function in skeletal muscle and in turn allow us to more clearly examine the impact of age per se on mitochondrial energetics...
January 24, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29300433/dynapenic-abdominal-obesity-increases-mortality-risk-among-english-and-brazilian-older-adults-a-10-year-follow-up-of-the-elsa-and-sabe-studies
#3
T da Silva Alexandre, S Scholes, J L Ferreira Santos, Y A de Oliveira Duarte, C de Oliveira
BACKGROUND/OBJECTIVE: There is little epidemiological evidence demonstrating that dynapenic abdominal obesity has higher mortality risk than dynapenia and abdominal obesity alone. Our main aim was to investigate whether dynapenia combined with abdominal obesity increases mortality risk among English and Brazilian older adults over ten-year follow-up. DESIGN: Cohort study. SETTING: United Kingdom and Brazil. PARTICIPANTS: Data came from 4,683 individuals from the English Longitudinal Study of Ageing (ELSA) and 1,490 from the Brazilian Health, Well-being and Aging study (SABE), hence the final sample of this study was 6,173 older adults...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29289723/diaphragm-muscle-dysfunction-in-patients-with-heart-failure
#4
Mari Miyagi, Yoshiharu Kinugasa, Takeshi Sota, Kensaku Yamada, Takuya Ishisugi, Masayuki Hirai, Kiyotaka Yanagihara, Nobuhiko Haruki, Koichi Matsubara, Masahiko Kato, Kazuhiro Yamamoto
BACKGROUND: Inspiratory muscle weakness is associated with the development of exercise intolerance in patients with heart failure (HF). Ultrasound assessment of the diaphragm is used to evaluate respiratory muscle function, but its application in patients with HF remains undefined. We examined the relationship of diaphragm function as assessed by ultrasonography with inspiratory muscle strength and exercise tolerance in HF. METHODS AND RESULTS: Seventy-seven patients hospitalized with HF were enrolled...
December 28, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29278424/feasibility-of-systematic-handgrip-strength-testing-in-digestive-cancer-patients-treated-with-chemotherapy-the-fightdigo-study
#5
Marie-Amélie Ordan, Camille Mazza, Coralie Barbe, Marine Perrier, Damien Botsen, Yohann Renard, Johanna Moreau, Mathilde Brasseur, Barbara Taillière, Éric Bertin, Olivier Bouché
BACKGROUND: Handgrip strength (HGS) is a widely studied noninvasive test. Weak strength (dynapenia) seems to be associated with high morbidity and mortality in different populations, notably oncology populations. Despite this, HGS testing is not used in daily practice in oncology. The study was aimed at evaluating the feasibility and acceptability of HGS testing in patients with digestive cancer treated with ambulatory chemotherapy. METHODS: In this prospective, single-center study, enrolled patients were followed for 6 months...
December 26, 2017: Cancer
https://www.readbyqxmd.com/read/29212996/-a-comparison-of-the-associations-of-dynapenia-and-sarcopenia-with-fear-of-falling-in-elderly-diabetic-patients
#6
Satoshi Ida, Kazuya Murata, Yuki Ishihara, Kanako Imataka, Ryutaro Kaneko, Ryoko Fujiwara, Hiroka Takahashi
AIM: To comparatively investigate whether dynapenia and sarcopenia, as defined by the Asian Working Group for Sarcopenia (AWGS), are associated with fear of falling in elderly patients with diabetes. METHODS: The subjects were outpatients with diabetes who were at least 65 years of age when they visited our hospital. Sarcopenia was evaluated based on the AWGS definition. The cutoff values for the appendicular skeletal mass index (multi-frequency bioelectrical impedance method), grip strength, and walking speed were, respectively, 7...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/29091148/relation-between-functional-mobility-and-dynapenia-in-institutionalized-frail-elderly
#7
Antonio Vinicius Soares, Elessandra Marcelino, Késsia Cristina Maia, Noé Gomes Borges
OBJECTIVE: To investigate the relation between functional mobility and dynapenia in institutionalized frail elderly. METHODS: A descriptive, correlational study involving 26 institutionalized elderly men and women, mean age 82.3±6 years. The instruments employed were the Mini Mental State Examination, the Geriatric Depression Scale, the International Physical Activity Questionnaire, the Timed Up and Go test, a handgrip dynamometer and a portable dynamometer for large muscle groups (shoulder, elbow and hip flexors, knee extensors and ankle dorsiflexors)...
July 2017: Einstein
https://www.readbyqxmd.com/read/29033231/the-combination-of-dynapenia-and-abdominal-obesity-as-a-risk-factor-for-worse-trajectories-of-iadl-disability-among-older-adults
#8
Tiago da Silva Alexandre, Shaun Scholes, Jair Licio Ferreira Santos, Yeda Aparecida de Oliveira Duarte, Cesar de Oliveira
BACKGROUND/OBJECTIVES: The concept of dynapenic obesity has been gaining great attention recently. However, there is little epidemiological evidence demonstrating that dynapenic abdominal obese individuals have worse trajectories of disability than those with dynapenia and abdominal obesity alone. Our aim was to investigate whether dynapenia combined with abdominal obesity can result in worse trajectories of instrumental activities of daily living (IADL) among English and Brazilian older adults over eight and ten years of follow-up, respectively...
October 2, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28986697/targeting-mitochondrial-function-and-proteostasis-to-mitigate-dynapenia
#9
REVIEW
Robert V Musci, Karyn L Hamilton, Benjamin F Miller
Traditionally, interventions to treat skeletal muscle aging have largely targeted sarcopenia-the age-related loss of skeletal muscle mass. Dynapenia refers to the age-related loss in skeletal muscle function due to factors outside of muscle mass, which helps to inform treatment strategies for aging skeletal muscle. There is evidence that mechanisms to maintain protein homeostasis and proteostasis, deteriorate with age. One key mechanism to maintain proteostasis is protein turnover, which is an energetically costly process...
October 6, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28827697/gait-speed-rather-than-dynapenia-is-a-simple-indicator-for-complex-care-needs-a-cross-sectional-study-using-minimum-data-set
#10
Tzu-Ya Huang, Chih-Kuang Liang, Hsiu-Chu Shen, Hon-I Chen, Mei-Chen Liao, Ming-Yueh Chou, Yu-Te Lin, Liang-Kung Chen
The impact of dynapenia on the complexity of care for residents of long-term care facilities (LTCF) remains unclear. The present study evaluated associations between dynapenia, care problems and care complexity in 504 residents of Veterans Care Homes (VCHs) in Taiwan. Subjects with dynapenia, defined as low muscle strength (handgrip strength <26 kg), were older adults with lower body mass index (BMI), slow gait speed, and higher numbers of Resident Assessment Protocol (RAP) triggers. After adjusting for age, education, BMI, and Charlson's comorbidity index (CCI), only age, education, BMI and gait speed were independently associated with higher numbers of RAP triggers, but not dynapenia or handgrip strength (kg)...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28676289/differential-characteristics-of-skeletal-muscle-in-community-dwelling-older-adults
#11
Minoru Yamada, Yosuke Kimura, Daisuke Ishiyama, Naohito Nishio, Yuki Abe, Tomohiro Kakehi, Junko Fujimoto, Tomoya Tanaka, Shunsuke Ohji, Yuhei Otobe, Shingo Koyama, Yukiko Okajima, Hidenori Arai
BACKGROUND: Sarcopenia is diagnosed on the basis of skeletal muscle mass and muscle strength/function. However, more simple and accurate measures for muscle mass and muscle strength/function should be explored. OBJECTIVE: The aim of this study was to compare the skeletal muscle characteristics at each stage of sarcopenia (normal, presarcopenia, dynapenia, and sarcopenia) via ultrasonography, multifrequency bioelectrical impedance analysis (BIA), and physical assessment batteries in community-dwelling older adults...
July 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28647293/dynapenic-obesity-as-an-associated-factor-to-lipid-and-glucose-metabolism-disorders-and-metabolic-syndrome-in-older-adults%C3%A2-%C3%A2-findings-from-sabe-study
#12
Tiago da Silva Alexandre, Mylène Aubertin-Leheudre, Lívia Pinheiro Carvalho, Roberta de Oliveira Máximo, Ligiana Pires Corona, Tábatta Renata Pereira de Brito, Daniella Pires Nunes, Jair Licio Ferreira Santos, Yeda Aparecida de Oliveira Duarte, Maria Lúcia Lebrão
BACKGROUND & AIMS: There is little evidence showing that dynapenic obesity is associated with lipid and glucose metabolism disorders, high blood pressure, chronic disease and metabolic syndrome. Our aim was to analyze whether dynapenic abdominal obesity can be associated with lipid and glucose metabolism disorders, high blood pressure, metabolic syndrome and cardiovascular diseases in older adults living in São Paulo. METHODS: This cross-sectional study included 833 older adults who took part of the third wave of the Health, Well-being and Aging Study in 2010...
June 10, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28549839/vitamin-b12-deficiency-might-be-related-to-sarcopenia-in-older-adults
#13
Esra Ates Bulut, Pinar Soysal, Ali Ekrem Aydin, Ozge Dokuzlar, Suleyman Emre Kocyigit, Ahmet Turan Isik
Sarcopenia and dynapenia are related to repeated falls, mobility restriction, depression, frailty, increased mortality and morbidity. The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults. 403 patients, who attended to outpatient clinic and underwent comprehensive geriatric assessment, were included study. All cases' skeletal muscle mass (SMM), walking speed and hand grip strength were recorded by bioimpedance, 4meter walking test and hand dynamometer respectively...
September 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28462119/whole-body-vibration-as-a-potential-countermeasure-for-dynapenia-and-arterial-stiffness
#14
REVIEW
Arturo Figueroa, Salvador J Jaime, Stacey Alvarez-Alvarado
Age-related decreases in muscle mass and strength are associated with decreased mobility, quality of life, and increased cardiovascular risk. Coupled with the prevalence of obesity, the risk of death becomes substantially greater. Resistance training (RT) has a well-documented beneficial impact on muscle mass and strength in young and older adults, although the high-intensity needed to elicit these adaptations may have a detrimental or negligible impact on vascular function, specifically on arterial stiffness...
September 2016: Integrative Medicine Research
https://www.readbyqxmd.com/read/28329134/dynapenic-abdominal-obesity-as-a-predictor-of-worsening-disability-hospitalization-and-mortality-in-older-adults-results-from-the-inchianti-study
#15
Andrea P Rossi, Lara Bianchi, Stefano Volpato, Stefania Bandinelli, Jack Guralnik, Mauro Zamboni, Luigi Ferrucci
Background: There are relatively few prospective studies evaluating the combined effect of abdominal obesity and low muscle strength on mortality, hospitalization, and incident disability. The aim of this study was to prospectively evaluate the prognostic value of dynapenic abdominal obesity on incident disability, hospitalization, and mortality in the population of the InCHIANTI study. Methods: In 370 men and 476 women aged between 65 and 95 years, handgrip strength, waist circumference (WC), body mass index, interleukin-6, C-reactive protein, education, medications, smoking status, and comorbidities were evaluated at the baseline...
August 1, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28198733/clinical-relevance-of-sarcopenia-in-chronic-kidney-disease
#16
Ranjani N Moorthi, Keith G Avin
PURPOSE OF REVIEW: In this article, we review sarcopenia in chronic kidney disease (CKD). We aim to present how definitions of sarcopenia from the general population may pertain to those with CKD, its assessment by clinicians and emerging therapies for sarcopenia in CKD. For this review, we limit our description and recommendations to patients with CKD who are not on dialysis. RECENT FINDINGS: Poorer parameters of lean mass, strength and physical function are associated with worsening patient-centered outcomes such as limiting mobility, falls and mortality in CKD; however, the magnitude of these associations are different in those with and without CKD...
May 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28150387/assessment-of-maximal-handgrip-strength-how-many-attempts-are-needed
#17
Esmee M Reijnierse, Nynke de Jong, Marijke C Trappenburg, Gerard Jan Blauw, Gillian Butler-Browne, Helena Gapeyeva, Jean-Yves Hogrel, Jamie S McPhee, Marco V Narici, Sarianna Sipilä, Lauri Stenroth, Rob C van Lummel, Mirjam Pijnappels, Carel G M Meskers, Andrea B Maier
BACKGROUND: Handgrip strength (HGS) is used to identify individuals with low muscle strength (dynapenia). The influence of the number of attempts on maximal HGS is not yet known and may differ depending on age and health status. This study aimed to assess how many attempts of HGS are required to obtain maximal HGS. METHODS: Three cohorts (939 individuals) differing in age and health status were included. HGS was assessed three times and explored as continuous and dichotomous variable...
June 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28049446/a-cross-sectional-study-of-the-association-between-dynapenia-and-higher-level-functional-capacity-in-daily-living-in-community-dwelling-older-adults-in-japan
#18
Masaki Iwamura, Masao Kanauchi
BACKGROUND: There are many reports that dynapenia, sarcopenia and frailty each have associations with bodily function or with Instrumental Activities of Daily Living (IADL). However, studies that compare all three conditions and their effects on IADL are lacking. The purpose of this study is to examine associations of sarcopenia, frailty, and dynapenia with IADL. METHODS: Participants included 123 community-dwelling older adults (31 men, 92 women,) aged 65 years or older (75...
January 3, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/27914851/dynapenia-and-metabolic-health-in-obese-and-nonobese-adults-aged-70%C3%A2-years-and-older-the-life-study
#19
Mylène Aubertin-Leheudre, Stephen Anton, Daniel P Beavers, Todd M Manini, Roger Fielding, Ann Newman, Tim Church, Stephen B Kritchevsky, David Conroy, Mary M McDermott, Anda Botoseneanu, Michelle E Hauser, Marco Pahor
OBJECTIVE: The purpose of this study was to examine the relationship between dynapenia and metabolic risk factors in obese and nonobese older adults. METHODS: A total of 1453 men and women (age ≥70 years) from the Lifestyle Interventions and Independence for Elders (LIFE) Study were categorized as (1) nondynapenic/nonobese (NDYN-NO), (2) dynapenic/nonobese (DYN-NO), (3) nondynapenic/obese (NDYN-O), or (4) dynapenic/obese (DYN-O), based on muscle strength (Foundation for the National Institute of Health criteria) and body mass index...
April 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27832209/handgrip-strength-and-factors-associated-in-poor-elderly-assisted-at-a-primary-care-unit-in-rio-de-janeiro-brazil
#20
Valéria Teresa Saraiva Lino, Nádia Cristina Pinheiro Rodrigues, Gisele O'Dwyer, Mônica Kramer de Noronha Andrade, Inês Echenique Mattos, Margareth Crisóstomo Portela
INTRODUCTION: Sarcopenia is a condition diagnosed when the patient presents low muscle mass, plus low muscle strength or low physical performance. Muscle weakness in the oldest (dynapenia) is a major public health concern because it predicts future all-cause mortality and is associated with falls, disability, cardiovascular mortality and morbidity. Grip strength is a simple method for assessment of muscle function in clinical practice. OBJECTIVE: To estimate the grip strength and identify factors associated with handgrip strength variation in elderly people with low socioeconomic status...
2016: PloS One
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