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Facial palsy

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https://www.readbyqxmd.com/read/29344474/corneal-myofibroma-keloid-in-a-young-patient-with-neurofibromatosis-type-2
#1
Lisa Zimmermann, Thomas Reinhard, Clemens Lange, Steffen Heegaard, Claudia Auw-Haedrich
We present a 27-year-old male patient with neurofibromatosis type 2 (NF2), facial palsy, and lagophthalmos following acoustic neuroma removal and an impressing vascularized corneal tumor, which was excised. Histology showed a fibrous tumor with small vessels, and immunohistochemistry was positive for vimentin and negative for smooth muscle actin, S100, and GFAP. We assume a corneal myofibroma (keloid), which in this case rather represents a reactive lesion. This entity has not been described before in NF2 or in facial palsy-associated lagophthalmos in general...
November 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29343679/ramsay-hunt-syndrome-with-multiple-cranial-neuropathy-in-an-human-immunodeficiency-virus-hiv-patient
#2
Divya Arya, Tushar Bajaj, Jose Gonzalez, Rene Elkin
BACKGROUND Ramsay Hunt syndrome is a rare otologic complication resulting from varicella zoster virus reactivation that can present with a myriad of clinical presentations. Most common being triad of ear pain, vesicles at auricle, and ear canal with same side facial palsy. CASE REPORT We report a case of a 29-year-old male with a human immunodeficiency virus (HIV) infection who presented with left facial palsy, vesicles, pain in the left ear, dysphagia, dizziness, and headache resulting from multiple cranial nerves involvement such as cranial nerve V, VII, VIII, IX, and X...
January 18, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29343258/mass-spectrometric-profiling-of-cerebrospinal-fluid-reveals-metabolite-biomarkers-for-cns-involvement-in-varicella-zoster-virus-reactivation
#3
Maike Kuhn, Kurt-Wolfram Sühs, Manas K Akmatov, Frank Klawonn, Junxi Wang, Thomas Skripuletz, Volkhard Kaever, Martin Stangel, Frank Pessler
BACKGROUND: Varicella zoster virus (VZV) reactivation spans the spectrum from uncomplicated segmental herpes zoster to life-threatening disseminated CNS infection. Moreover, in the absence of a small animal model for this human pathogen, studies of pathogenesis at the organismal level depend on analysis of human biosamples. Changes in cerebrospinal fluid (CSF) metabolites may reflect critical aspects of host responses and end-organ damage in neuroinfection and neuroinflammation. We therefore applied a targeted metabolomics screen of CSF to three clinically distinct forms of VZV reactivation and infectious and non-infectious disease controls in order to identify biomarkers for CNS involvement in VZV reactivation...
January 17, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29336632/m%C3%A3-bius-syndrome-with-cardiac-rhabdomyomas
#4
Aimee Verner, Swati Agarwal-Sinha, Frank Yanfeng Han
BACKGROUND: Möbius syndrome is a rare congenital condition which presents not merely with 6th and 7th nerve palsies, but involves gaze paresis associated with craniofacial, limb, and other abnormalities. Heterogeneity is well known in patients with Möbius syndrome and rather than being of familial inheritance based on rare cases, it is much more recognized as a sporadic syndrome. We report an infant with features of congenital Möbius syndrome associated with cardiac rhabdomyomas in the absence of tuberous sclerosis...
January 16, 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29326960/risk-factors-for-clinician-diagnosed-lyme-arthritis-facial-palsy-carditis-and-meningitis-in-patients-from-high-incidence-states
#5
Natalie A Kwit, Christina A Nelson, Ryan Max, Paul S Mead
Background: Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods: Patients from high-incidence states treated for LD during 2005-2014 were identified in a nationwide insurance claims database using the International Classification of Diseases, Ninth Revision code for LD (088...
January 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29325920/twenty-four-syndrome-an-untold-presentation-of-pontine-hemorrhage
#6
Ummer Karadan, Ramesh N Supreeth, Robin George Manappallil, Chellenton Jayakrishnan
Pontine hemorrhages are relatively uncommon. Various atypical manifestations of pontine stroke like eight-and-a-half syndrome, fifteen-and-a-half syndrome, and sixteen syndrome have been described in the past. We came across a case of pontine bleed that presented with bilateral facial palsy, bilateral horizontal gaze palsy, and contralateral sensorineural hearing loss accounting to the hitherto not described "twenty-four syndrome" with Horner's syndrome and left hemiparesis.
January 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29319192/characteristics-of-patients-with-acute-peripheral-facial-palsy-showing-varicella-zoster-virus-dna-in-saliva
#7
Dong Sik Chang, Jun Lee, Sun Ae Shin, Ho Yun Lee
Infection caused by Varicella zoster virus (VZV) is a common etiology of acute peripheral facial palsy (APFP). We aimed to assess the clinical significance of detecting VZV DNA from the saliva of patients with APFP. Saliva collected from thirty-six patients with unilateral APFP at initial visit was analyzed to detect VZV DNA by polymerase chain reaction. The House-Brackmann (HB) scale was used to evaluate FP severity on admission day, at week 2, and at weeks 10-12 after start of treatment. Among the 28 patients without rash, VZV DNA was detected in 3 patients (10...
January 10, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29315450/facial-nerve-schwannoma-a-case-report-radiological-features-and-literature-review
#8
Giulia Pilloni, Barbara Massa Mico, Roberto Altieri, Francesco Zenga, Alessandro Ducati, Diego Garbossa, Fulvio Tartara
Facial nerve schwannoma localized in the middle fossa is a rare lesion. We report a case of a facial nerve schwannoma in a 30-year-old male presenting with facial nerve palsy. Magnetic resonance imaging (MRI) showed a 3 cm diameter tumor of the right middle fossa. The tumor was removed using a sub-temporal approach. Intraoperative monitoring allowed for identification of the facial nerve, so it was not damaged during the surgical excision. Neurological clinical examination at discharge demonstrated moderate facial nerve improvement (Grade III House-Brackmann)...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29315193/the-application-of-sigmoid-sinus-tunnel-packing-or-push-packing-of-the-inferior-petrous-sinus-in-the-microsurgical-management-of-jugular-paragangliomas
#9
Mi Jang, Hongyan Liu, Chunfu Dai
OBJECTIVE: To analyze the outcomes of microsurgically treated jugular paragangliomas with control of bleeding from the inferior petrous sinus. STUDY DESIGN: Retrospective patient review. SETTING: A single university hospital. PATIENTS: Forty-three patients with jugular paragangliomas were diagnosed in the past 7 years in our clinic. MAIN OUTCOME MEASURES: Surgical tumor control, intraoperative blood loss, intraoperative management of the facial nerve, and the preoperative and postoperative function of the lower central nerves...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29301803/extramedullary-plasmacytoma-rare-neoplasm-of-parotid-gland
#10
Sehrish Abrar, Nasir Ali, Bilal Mazhar Qureshi, Ahmed Nadeem Abbasi
A 45-year-old man presented with left-sided facial swelling. Initial excisional biopsy was done somewhere else without prior imaging and it came out to be pleomorphic adenoma; local imaging after biopsy showed mass over the left parotid gland with ipsilateral lymphadenopathy. On examination, there was a well-circumscribed mass with signs of left facial nerve palsy. He underwent left radical parotidectomy with ipsilateral modified radical neck dissection, and per operatively, it came out to be neoplastic lesion...
January 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29301560/delayed-facial-nerve-decompression-for-severe-refractory-cases-of-bell-s-palsy-a-25-year-experience
#11
Ilyes Berania, Mohamed Awad, Issam Saliba, Jean-Jacques Dufour, Marc-Elie Nader
BACKGROUND: This study aims to assess the effectiveness of delayed facial nerve decompression for Bell's palsy (BP). METHODS: We performed a retrospective case review of all patients having undergone facial nerve decompression for severe refractory BP between 1984 and 2009 at our tertiary referral center. Demographics, timing between onset of symptoms and surgical decompression, degree of facial nerve dysfunction pre- and post-operatively, follow-up length after surgery and postoperative complications were recorded...
January 4, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29299510/long-term-oncologic-and-functional-outcome-in-pleomorphic-adenomas-of-the-submandibular-gland
#12
Konstantinos Mantsopoulos, Miguel Goncalves, Mirco Schapher, Heinrich Iro
Objectives: The aim of the study was to evaluate the oncologic and functional long-term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. Methods: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulectomy between 2000 and 2016 were studied retrospectively. Patients who had had revision after external primary surgery, as well as patients with insufficient data were excluded from our study sample...
December 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29289389/tubb3-e410k-syndrome-with-osteoporosis-and-cough-syncope-in-a-patient-previously-diagnosed-with-atypical-moebius-syndrome
#13
Yasuko Nakamura, Hiroshi Matsumoto, Kiyotaka Zaha, Kenji Uematsu, Shigeaki Nonoyama
BACKGROUND: A heterozygous c.1228G > A p.E410K mutation in TUBB3 encoding neuronal-specific β-tubulin isotype 3 causes TUBB3 E410K syndrome, which exhibits a wide range of neurological and endocrinological abnormalities. CASE DESCRIPTION: The patient is a 31-year-old Japanese woman who was diagnosed with atypical Moebius syndrome because of congenital facial weakness and extraocular ophthalmoplegia sparing abduction. She suffered a femoral neck fracture at 23 years of age, and radiological and endocrinological studies revealed osteoporosis because of hypogonadotropic hypogonadism...
December 27, 2017: Brain & Development
https://www.readbyqxmd.com/read/29284561/does-type-2-diabetes-mellitus-affect-the-healing-of-bell-s-palsy-in-adults
#14
Sultan Şevik Eliçora, Duygu Erdem
OBJECTIVES: Bell's palsy (BP) is defined as an acute facial weakness of unknown cause. Many factors affecting the healing of BP have been identified; 1 factor commonly considered relevant is the presence of type 2 diabetes mellitus. Our aim was to investigate the effects of diabetes on the healing of BP. METHODS: Sixty patients with BP were followed up for 1 to 3 years and were divided into 2 groups, those with and those without type 2 diabetes. All were prescribed prednisone (initially 1 mg/kg per day, with a tapered dose reduction) and acyclovir (200 mg orally every 4 h, 5 times daily, for 5 days)...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29283103/a-view-of-the-therapy-for-bell-s-palsy-based-on-molecular-biological-analyses-of-facial-muscles
#15
Hiroshi Moriyama, Nobuyuki Mitsukawa, Masahiro Itoh, Naruhito Otsuka
OBJECTIVE: Details regarding the molecular biological features of Bell's palsy have not been widely reported in textbooks. We genetically analyzed facial muscles and clarified these points. MATERIALS AND METHODS: We performed genetic analysis of facial muscle specimens from Japanese patients with severe (House-Brackmann facial nerve grading system V) and moderate (House-Brackmann facial nerve grading system III) dysfunction due to Bell's palsy. Microarray analysis of gene expression was performed using specimens from the healthy and affected sides, and gene expression was compared...
December 14, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29278020/diagnosis-and-management-of-lyme-neuroborreliosis
#16
John J Halperin
The nervous system is involved in 10-15% of patients infected with B. burgdorferi, B. afzelii and B. garinii. This review will address widespread misconceptions about the clinical phenomenology, diagnostic approach and response to treatment of neuroborreliosis. Areas covered: Improvements in diagnostic testing have allowed better definition of the clinical spectrum of neuroborreliosis, with lymphocytic meningitis and uni- or multifocal inflammation of peripheral/cranial nerves predominating. Despite widespread concern that post-treatment cognitive/behavioral symptoms might be attributable to persisting infection or aberrant inflammation within the central nervous system a large body of evidence indicates this is extremely improbable...
January 2018: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29250758/refractory-facial-paralysis-a-case-report
#17
Yu-Wei Hsu, Jiunn-Tay Lee, Yi-Shu Liao, Shin Nieh, Chun-An Cheng, Chia-Kuang Tsai
PURPOSE: To present a case of salivary gland malignancy initially mimicking Bell's palsy. CASE REPORT: A 75-year-old woman with hypertension visited our neurological outpatient department,complaining of persistent right facial paralysis for more than a year after oral glucocorticoid therapy with recent development of vertigo and unsteady gait. She was previously diagnosed as having Bell's palsy and was prescribed oral glucocorticoid. However, her right facial muscles were still completely paralyzed, with no signs of improvement...
June 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29245281/spontaneous-spinal-epidural-hematoma-mimicking-transient-ischemic-attack-a-case-report
#18
Chuqiao Li, Rui He, Xiaoqiang Li, Yulan Zhong, Li Ling, Fangming Li
RATIONALE: Spontaneous spinal epidural hematoma (SSEH) is a rare but highly disabling neurological emergency. The initial presentations are variable. Most patients of SSEH present with paraplegia or tetraplegia clinically, but recurrent hemiparesis with complete spontaneous recovery, mimicking transient ischemic attack (TIA), is a very rare initial presentation of SSEH. PATIENT CONCERNS: A 71-year-old female presented to the emergency department with 2 episodes of transient right hemiparesis in 5 hours...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29243534/eight-and-a-half-syndrome-caused-by-a-pontine-hemorrhage-a-case-report-and-review-of-the-literature
#19
Nian-Ge Xia, Yan-Yan Chen, Jia Li, Xi Chen, Zu-Sen Ye, Si-Yan Chen, Zhen-Guo Zhu
BACKGROUND: Eight-and-a-half syndrome is caused by a lesion in the dorsal tegmentum of the caudal pons involving parapontine reticular formation (PPRF) and the median longitudinal fasciculus (MLF), as well as the nucleus and/or the fasciculus of the facial nerve. It is characterized by one-and-a-half syndrome and an ipsilateral cranial nerve VII palsy. There are also many variants of eight-and-a-half syndrome has been described, including nine syndrome, thirteen-and-a-half syndrome, and fifteen-and-a-half syndrome...
December 15, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29238686/mutilating-lesions-of-face
#20
Kavita Sachdeva, Aparaajita Upadhyay
The destructive lesions affect midline facial areas causing extensive destruction. These lesions are challenging till date due to peculiarity in presentation and non availability of any single objective test. An attempt has been done to evaluate these different clinical presentations of lesions presenting at a single centre and the challenges faced by us at a tertiary government setup. Prospective study done on 15 patients presenting in department during period of 2006-2016. After a detailed history, hematological and biochemical markers, ESR, radiographical tests, pus culture, C ANCA, CECT PNS and histopathogical evaluation were done...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
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